IMP

Process View

Homo sapiens

3 genes annotated in human

regulation of humoral immune response mediated by circulating immunoglobulin

Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of humoral immune response mediated by circulating immunoglobulin"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of humoral immune response mediated by circulating immunoglobulin" (in gray)

Name	Description	Probability	Func Analog Organism
SYK	spleen tyrosine kinase	1.000
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.991
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.981
CD22	CD22 molecule	0.978
CD164	CD164 molecule, sialomucin	0.864
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.809	Mouse
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.768	Mouse
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.563
EPOR	erythropoietin receptor	0.442
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.279
UBASH3B	ubiquitin associated and SH3 domain containing B	0.279
PECAM1	platelet/endothelial cell adhesion molecule	0.248
CPD	carboxypeptidase D	0.225
PILRA	paired immunoglobin-like type 2 receptor alpha	0.220
ADAM10	ADAM metallopeptidase domain 10	0.204
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.192
CD33	CD33 molecule	0.164
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.156
BLNK	B-cell linker	0.154
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.151
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.122
IL4R	interleukin 4 receptor	0.115
CD19	CD19 molecule	0.108
SIGLEC10	sialic acid binding Ig-like lectin 10	0.107
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.095
CD247	CD247 molecule	0.088
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.080
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.073
CR2	complement component (3d/Epstein Barr virus) receptor 2	0.071	Human
FYB	FYN binding protein	0.060
IFNGR1	interferon gamma receptor 1	0.059
ALOX5	arachidonate 5-lipoxygenase	0.057
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.046
CD72	CD72 molecule	0.038
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.036	Mouse
SLAMF1	signaling lymphocytic activation molecule family member 1	0.036
PLCG1	phospholipase C, gamma 1	0.035
SNAP23	synaptosomal-associated protein, 23kDa	0.035
GPR65	G protein-coupled receptor 65	0.033
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.032
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.032
CLEC7A	C-type lectin domain family 7, member A	0.031
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.030	Mouse
PLEK	pleckstrin	0.028
SIRPB1	signal-regulatory protein beta 1	0.028
KIR2DL1	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	0.027
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.026
PICALM	phosphatidylinositol binding clathrin assembly protein	0.025
SH3BP2	SH3-domain binding protein 2	0.025
CXCR5	chemokine (C-X-C motif) receptor 5	0.024
PRKCQ	protein kinase C, theta	0.024
MNDA	myeloid cell nuclear differentiation antigen	0.022
GRAP2	GRB2-related adaptor protein 2	0.022
TM9SF2	transmembrane 9 superfamily member 2	0.022
IGSF6	immunoglobulin superfamily, member 6	0.022
NCF4	neutrophil cytosolic factor 4, 40kDa	0.022
SAT1	spermidine/spermine N1-acetyltransferase 1	0.021
NAMPT	nicotinamide phosphoribosyltransferase	0.021
CD79B	CD79b molecule, immunoglobulin-associated beta	0.021
TMEM59	transmembrane protein 59	0.020
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.020
SOCS3	suppressor of cytokine signaling 3	0.020
VAV1	vav 1 guanine nucleotide exchange factor	0.019
ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1	0.019
SERINC3	serine incorporator 3	0.019
SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	0.018
CD1C	CD1c molecule	0.017
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.017
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.016
RGS14	regulator of G-protein signaling 14	0.016
CD93	CD93 molecule	0.015
KYNU	kynureninase	0.015
RIOK3	RIO kinase 3 (yeast)	0.015
IL13RA1	interleukin 13 receptor, alpha 1	0.014
IRF4	interferon regulatory factor 4	0.014
CIITA	class II, major histocompatibility complex, transactivator	0.014
DBNL	drebrin-like	0.014
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.013
TYROBP	TYRO protein tyrosine kinase binding protein	0.013
LRMP	lymphoid-restricted membrane protein	0.013
FCRLA	Fc receptor-like A	0.013
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.013
LCK	lymphocyte-specific protein tyrosine kinase	0.013
SH2D2A	SH2 domain containing 2A	0.013
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.013
SH2D1A	SH2 domain containing 1A	0.012
CXCR2	chemokine (C-X-C motif) receptor 2	0.012
RPUSD1	RNA pseudouridylate synthase domain containing 1	0.012
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.012
CD52	CD52 molecule	0.012
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
APCS	amyloid P component, serum	0.011
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.011
CCR6	chemokine (C-C motif) receptor 6	0.011
SIT1	signaling threshold regulating transmembrane adaptor 1	0.010
CPNE3	copine III	0.010
TCL1A	T-cell leukemia/lymphoma 1A	0.010
CD53	CD53 molecule	0.010
CD1D	CD1d molecule	0.010
AQP9	aquaporin 9	0.010