IMP
Process View
interferon gamma mediated signaling pathway
A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "interferon gamma mediated signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.851 | Human | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.826 | Human | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.818 | ||
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.504 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.367 | ||
| EGFR | epidermal growth factor receptor | 0.364 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.348 | Human | |
| HCK | hemopoietic cell kinase | 0.326 | Human | |
| JAK2 | Janus kinase 2 | 0.302 | Rat | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.275 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.225 | ||
| IRF9 | interferon regulatory factor 9 | 0.195 | ||
| NMI | N-myc (and STAT) interactor | 0.171 | ||
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.167 | Human | |
| RXRA | retinoid X receptor, alpha | 0.163 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.157 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.156 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.153 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.130 | ||
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.122 | ||
| STAP2 | signal transducing adaptor family member 2 | 0.107 | ||
| INSR | insulin receptor | 0.083 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.080 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.076 | ||
| ESR1 | estrogen receptor 1 | 0.062 | ||
| GHR | growth hormone receptor | 0.057 | ||
| IL4R | interleukin 4 receptor | 0.055 | ||
| SPRR2A | small proline-rich protein 2A | 0.055 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.050 | ||
| SYK | spleen tyrosine kinase | 0.049 | ||
| NCK1 | NCK adaptor protein 1 | 0.046 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.045 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.044 | Human | |
| GRB2 | growth factor receptor-bound protein 2 | 0.042 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.042 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.040 | Human | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.039 | ||
| IL2RB | interleukin 2 receptor, beta | 0.038 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.035 | ||
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.031 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.030 | ||
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.028 | Human | |
| ITK | IL2-inducible T-cell kinase | 0.025 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.025 | ||
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.024 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.024 | ||
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.020 | Human | |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.019 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.019 | ||
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.017 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.017 | ||
| SP1 | Sp1 transcription factor | 0.016 | ||
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.016 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.016 | ||
| GAS7 | growth arrest-specific 7 | 0.015 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.014 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.014 | ||
| MED10 | mediator complex subunit 10 | 0.014 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.013 | Human | |
| DTX3L | deltex 3-like (Drosophila) | 0.013 | ||
| JAK1 | Janus kinase 1 | 0.012 | ||
| PGR | progesterone receptor | 0.012 | ||
| TNS4 | tensin 4 | 0.012 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.012 | ||
| SH2B1 | SH2B adaptor protein 1 | 0.011 | ||
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.011 | ||
| MED28 | mediator complex subunit 28 | 0.011 | ||
| GBP5 | guanylate binding protein 5 | 0.011 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.010 |