IMP

Process View

Homo sapiens

3 genes annotated in human

positive regulation of viral entry into host cell

Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of viral entry into host cell"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of viral entry into host cell" (in gray)

Name	Description	Probability	Func Analog Organism
MED15	mediator complex subunit 15	0.983
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.786
TRIM5	tripartite motif containing 5	0.716	Human Mouse
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.696
ZNF263	zinc finger protein 263	0.668
TRIM39	tripartite motif containing 39	0.472	Human
IFI44	interferon-induced protein 44	0.269
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.259
SP100	SP100 nuclear antigen	0.222
RNF126	ring finger protein 126	0.215
TRIM43	tripartite motif containing 43	0.204
TRIM17	tripartite motif containing 17	0.189	Human
IRF9	interferon regulatory factor 9	0.171
PML	promyelocytic leukemia	0.165
TRIM21	tripartite motif containing 21	0.152	Human Mouse
IFI16	interferon, gamma-inducible protein 16	0.149
TRIM8	tripartite motif containing 8	0.147
MCOLN1	mucolipin 1	0.145
RNF5	ring finger protein 5	0.144
SP110	SP110 nuclear body protein	0.139
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.133
PLSCR1	phospholipid scramblase 1	0.130
TRIM26	tripartite motif containing 26	0.125
DAXX	death-domain associated protein	0.116
DTX3L	deltex 3-like (Drosophila)	0.107
ARIH2	ariadne homolog 2 (Drosophila)	0.096
ZNRF1	zinc and ring finger 1	0.093
TRIM32	tripartite motif containing 32	0.086
ZNF473	zinc finger protein 473	0.084
TRIM34	tripartite motif containing 34	0.081
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.074
MR1	major histocompatibility complex, class I-related	0.069
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.054
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.052
TRIM41	tripartite motif containing 41	0.049	Human
RNF11	ring finger protein 11	0.042
BTN3A2	butyrophilin, subfamily 3, member A2	0.042
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.041
TRIM35	tripartite motif containing 35	0.040
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.039
RNF4	ring finger protein 4	0.039
CTSO	cathepsin O	0.038
TUBGCP4	tubulin, gamma complex associated protein 4	0.037
TRIM52	tripartite motif containing 52	0.036
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.036
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.035
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.034
MKRN3	makorin ring finger protein 3	0.034
RTP4	receptor (chemosensory) transporter protein 4	0.032
RNF130	ring finger protein 130	0.032
BFAR	bifunctional apoptosis regulator	0.032
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.032
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.031
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.031
IRF2	interferon regulatory factor 2	0.031
NMI	N-myc (and STAT) interactor	0.030
RNF166	ring finger protein 166	0.028
SAMD9	sterile alpha motif domain containing 9	0.028
PLCD4	phospholipase C, delta 4	0.027
FADD	Fas (TNFRSF6)-associated via death domain	0.027
GBP1	guanylate binding protein 1, interferon-inducible	0.027
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.025
MUC4	mucin 4, cell surface associated	0.024
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.023
MAGEF1	melanoma antigen family F, 1	0.023
RNF114	ring finger protein 114	0.022
CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	0.022
ZBTB8A	zinc finger and BTB domain containing 8A	0.021
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.021
RNF10	ring finger protein 10	0.021
WFDC2	WAP four-disulfide core domain 2	0.020
TRIM4	tripartite motif containing 4	0.020	Human
RNF25	ring finger protein 25	0.020
MEX3B	mex-3 homolog B (C. elegans)	0.020
TRIM6	tripartite motif containing 6	0.020	Human
PHF11	PHD finger protein 11	0.019
C19orf66	chromosome 19 open reading frame 66	0.019
UBTD1	ubiquitin domain containing 1	0.019
SREBF1	sterol regulatory element binding transcription factor 1	0.019
HIPK2	homeodomain interacting protein kinase 2	0.018
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.018
CHFR	checkpoint with forkhead and ring finger domains	0.018
ZCCHC6	zinc finger, CCHC domain containing 6	0.018
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.017
TDRD7	tudor domain containing 7	0.017
MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	0.017
RLIM	ring finger protein, LIM domain interacting	0.017
NFYC	nuclear transcription factor Y, gamma	0.016
RMND5B	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.016
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.016
RHD	Rh blood group, D antigen	0.015
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.015
MYD88	myeloid differentiation primary response gene (88)	0.015
RAB25	RAB25, member RAS oncogene family	0.015
FAS	Fas (TNF receptor superfamily, member 6)	0.014
PDZK1IP1	PDZK1 interacting protein 1	0.013
OSBP2	oxysterol binding protein 2	0.013
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.013
VIL1	villin 1	0.013
SPTB	spectrin, beta, erythrocytic	0.013
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.013
RHAG	Rh-associated glycoprotein	0.013
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.013
IFIT5	interferon-induced protein with tetratricopeptide repeats 5	0.013
TMC5	transmembrane channel-like 5	0.012
SLC44A4	solute carrier family 44, member 4	0.012
RNF185	ring finger protein 185	0.012
DTX2	deltex homolog 2 (Drosophila)	0.012
SDSL	serine dehydratase-like	0.012
MBD4	methyl-CpG binding domain protein 4	0.012
GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.012
PTPRH	protein tyrosine phosphatase, receptor type, H	0.012
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.012
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.012
B3GNT3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	0.012
RNF31	ring finger protein 31	0.012
RAB17	RAB17, member RAS oncogene family	0.012
FBF1	Fas (TNFRSF6) binding factor 1	0.012
ZBTB48	zinc finger and BTB domain containing 48	0.011
GFI1B	growth factor independent 1B transcription repressor	0.011
TRIM55	tripartite motif containing 55	0.011
PARP12	poly (ADP-ribose) polymerase family, member 12	0.011
EPS8L1	EPS8-like 1	0.011
SAMD9L	sterile alpha motif domain containing 9-like	0.011
FXYD3	FXYD domain containing ion transport regulator 3	0.011
GYPE	glycophorin E (MNS blood group)	0.011
ANXA1	annexin A1	0.011
OVOL1	ovo-like 1(Drosophila)	0.011
GIMAP2	GTPase, IMAP family member 2	0.011
PSCA	prostate stem cell antigen	0.011
TRIM38	tripartite motif containing 38	0.011
DUOX2	dual oxidase 2	0.011
CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	0.011
FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	0.010
ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	0.010
BTN3A3	butyrophilin, subfamily 3, member A3	0.010
MAGEA11	melanoma antigen family A, 11	0.010
PRSS8	protease, serine, 8	0.010
PLA2G10	phospholipase A2, group X	0.010
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.010
TRIM14	tripartite motif containing 14	0.010