The network for 'positive regulation of viral entry into host cell' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of viral entry into host cell

Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.

Homo sapiens
Name Description Probability Func Analog Organism
MED15 mediator complex subunit 15 0.983
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.786
TRIM5 tripartite motif containing 5 0.716
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.696
ZNF263 zinc finger protein 263 0.668
TRIM39 tripartite motif containing 39 0.472
IFI44 interferon-induced protein 44 0.269
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.259
SP100 SP100 nuclear antigen 0.222
RNF126 ring finger protein 126 0.215
TRIM43 tripartite motif containing 43 0.204
TRIM17 tripartite motif containing 17 0.189
IRF9 interferon regulatory factor 9 0.171
PML promyelocytic leukemia 0.165
TRIM21 tripartite motif containing 21 0.152
IFI16 interferon, gamma-inducible protein 16 0.149
TRIM8 tripartite motif containing 8 0.147
MCOLN1 mucolipin 1 0.145
RNF5 ring finger protein 5 0.144
SP110 SP110 nuclear body protein 0.139
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.133
PLSCR1 phospholipid scramblase 1 0.130
TRIM26 tripartite motif containing 26 0.125
DAXX death-domain associated protein 0.116
DTX3L deltex 3-like (Drosophila) 0.107
ARIH2 ariadne homolog 2 (Drosophila) 0.096
ZNRF1 zinc and ring finger 1 0.093
TRIM32 tripartite motif containing 32 0.086
ZNF473 zinc finger protein 473 0.084
TRIM34 tripartite motif containing 34 0.081
UBE2U ubiquitin-conjugating enzyme E2U (putative) 0.074
MR1 major histocompatibility complex, class I-related 0.069
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.054
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.052
TRIM41 tripartite motif containing 41 0.049
RNF11 ring finger protein 11 0.042
BTN3A2 butyrophilin, subfamily 3, member A2 0.042
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.041
TRIM35 tripartite motif containing 35 0.040
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.039
RNF4 ring finger protein 4 0.039
CTSO cathepsin O 0.038
TUBGCP4 tubulin, gamma complex associated protein 4 0.037
TRIM52 tripartite motif containing 52 0.036
TRIM6-TRIM34 TRIM6-TRIM34 readthrough 0.036
PIK3C2B phosphoinositide-3-kinase, class 2, beta polypeptide 0.035
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.034
MKRN3 makorin ring finger protein 3 0.034
RTP4 receptor (chemosensory) transporter protein 4 0.032
RNF130 ring finger protein 130 0.032
BFAR bifunctional apoptosis regulator 0.032
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.032
OAS1 2',5'-oligoadenylate synthetase 1, 40/46kDa 0.031
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.031
IRF2 interferon regulatory factor 2 0.031
NMI N-myc (and STAT) interactor 0.030
RNF166 ring finger protein 166 0.028
SAMD9 sterile alpha motif domain containing 9 0.028
PLCD4 phospholipase C, delta 4 0.027
FADD Fas (TNFRSF6)-associated via death domain 0.027
GBP1 guanylate binding protein 1, interferon-inducible 0.027
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.025
MUC4 mucin 4, cell surface associated 0.024
UBE2Z ubiquitin-conjugating enzyme E2Z 0.023
MAGEF1 melanoma antigen family F, 1 0.023
RNF114 ring finger protein 114 0.022
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.022
ZBTB8A zinc finger and BTB domain containing 8A 0.021
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.021
RNF10 ring finger protein 10 0.021
WFDC2 WAP four-disulfide core domain 2 0.020
TRIM4 tripartite motif containing 4 0.020
RNF25 ring finger protein 25 0.020
MEX3B mex-3 homolog B (C. elegans) 0.020
TRIM6 tripartite motif containing 6 0.020
PHF11 PHD finger protein 11 0.019
C19orf66 chromosome 19 open reading frame 66 0.019
UBTD1 ubiquitin domain containing 1 0.019
SREBF1 sterol regulatory element binding transcription factor 1 0.019
HIPK2 homeodomain interacting protein kinase 2 0.018
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.018
CHFR checkpoint with forkhead and ring finger domains 0.018
ZCCHC6 zinc finger, CCHC domain containing 6 0.018
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.017
TDRD7 tudor domain containing 7 0.017
MAGEA1 melanoma antigen family A, 1 (directs expression of antigen MZ2-E) 0.017
RLIM ring finger protein, LIM domain interacting 0.017
NFYC nuclear transcription factor Y, gamma 0.016
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 0.016
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.016
RHD Rh blood group, D antigen 0.015
MX2 myxovirus (influenza virus) resistance 2 (mouse) 0.015
MYD88 myeloid differentiation primary response gene (88) 0.015
RAB25 RAB25, member RAS oncogene family 0.015
FAS Fas (TNF receptor superfamily, member 6) 0.014
PDZK1IP1 PDZK1 interacting protein 1 0.013
OSBP2 oxysterol binding protein 2 0.013
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.013
VIL1 villin 1 0.013
SPTB spectrin, beta, erythrocytic 0.013
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
N Notch 0.239
Ras85D Ras oncogene at 85D 0.115
phl pole hole 0.037
dpp decapentaplegic 0.036
Egfr Epidermal growth factor receptor 0.034
Dl Delta 0.034
put punt 0.029
wg wingless 0.027
arm armadillo 0.022
gl glass 0.022
E(z) Enhancer of zeste 0.022
spi spitz 0.012
EcR Ecdysone receptor 0.012
sax saxophone 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Trim30d tripartite motif-containing 30D 0.975
Trim30a tripartite motif-containing 30A 0.923
Stat1 signal transducer and activator of transcription 1 0.692
Gbp7 guanylate binding protein 7 0.665
Trim12a tripartite motif-containing 12A 0.543
Stat2 signal transducer and activator of transcription 2 0.536
Usp18 ubiquitin specific peptidase 18 0.535
Irf9 interferon regulatory factor 9 0.515
Parp14 poly (ADP-ribose) polymerase family, member 14 0.466
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.447
Rtp4 receptor transporter protein 4 0.384
Ifi44 interferon-induced protein 44 0.313
Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 0.308
Gbp3 guanylate binding protein 3 0.274
Ifi203 interferon activated gene 203 0.259
Irgm1 immunity-related GTPase family M member 1 0.210
Herc6 hect domain and RLD 6 0.174
Trim34a tripartite motif-containing 34A 0.143
Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.143
Ifi47 interferon gamma inducible protein 47 0.132
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.123
Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 0.119
Ifih1 interferon induced with helicase C domain 1 0.118
Oas1b 2'-5' oligoadenylate synthetase 1B 0.116
Trim12c tripartite motif-containing 12C 0.112
Irgm2 immunity-related GTPase family M member 2 0.104
Samd9l sterile alpha motif domain containing 9-like 0.100
Parp9 poly (ADP-ribose) polymerase family, member 9 0.098
Trim5 tripartite motif-containing 5 0.092
Sp100 nuclear antigen Sp100 0.090
Txndc5 thioredoxin domain containing 5 0.083
Iigp1 interferon inducible GTPase 1 0.083
Lrrc59 leucine rich repeat containing 59 0.079
Rsad2 radical S-adenosyl methionine domain containing 2 0.074
Mx1 myxovirus (influenza virus) resistance 1 0.074
Trim21 tripartite motif-containing 21 0.074
Dtx3l deltex 3-like (Drosophila) 0.071
Clk2 CDC-like kinase 2 0.067
Epsti1 epithelial stromal interaction 1 (breast) 0.063
Anks3 ankyrin repeat and sterile alpha motif domain containing 3 0.061
Oasl2 2'-5' oligoadenylate synthetase-like 2 0.059
Kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.054
Gbp2 guanylate binding protein 2 0.050
Srm spermidine synthase 0.048
BC006779 cDNA sequence BC006779 0.048
Pyhin1 pyrin and HIN domain family, member 1 0.048
Surf4 surfeit gene 4 0.044
Csprs component of Sp100-rs 0.043
Cmpk2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.043
Oas3 2'-5' oligoadenylate synthetase 3 0.042
Uba7 ubiquitin-like modifier activating enzyme 7 0.040
Mnda myeloid cell nuclear differentiation antigen 0.039
Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.035
B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.035
Zc3hav1 zinc finger CCCH type, antiviral 1 0.035
Gorasp2 golgi reassembly stacking protein 2 0.034
Gpa33 glycoprotein A33 (transmembrane) 0.033
Trmt2a TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae) 0.032
Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.032
Fam193b family with sequence similarity 193, member B 0.032
Taf1a TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A 0.031
E4f1 E4F transcription factor 1 0.030
Hyou1 hypoxia up-regulated 1 0.029
Tlr3 toll-like receptor 3 0.028
Xaf1 XIAP associated factor 1 0.027
Asb17 ankyrin repeat and SOCS box-containing 17 0.027
Zbp1 Z-DNA binding protein 1 0.026
Fbxl12 F-box and leucine-rich repeat protein 12 0.026
Nxf1 nuclear RNA export factor 1 homolog (S. cerevisiae) 0.026
Mndal myeloid nuclear differentiation antigen like 0.025
D14Ertd668e DNA segment, Chr 14, ERATO Doi 668, expressed 0.025
Oasl1 2'-5' oligoadenylate synthetase-like 1 0.025
Pydc4 pyrin domain containing 4 0.025
Sfi1 Sfi1 homolog, spindle assembly associated (yeast) 0.024
H2-M3 histocompatibility 2, M region locus 3 0.024
Top3b topoisomerase (DNA) III beta 0.023
Slc35b1 solute carrier family 35, member B1 0.023
Tnk1 tyrosine kinase, non-receptor, 1 0.023
Gbp6 guanylate binding protein 6 0.023
Samhd1 SAM domain and HD domain, 1 0.022
Zufsp zinc finger with UFM1-specific peptidase domain 0.022
2210407C18Rik RIKEN cDNA 2210407C18 gene 0.022
Stx5a syntaxin 5A 0.021
Lrrc45 leucine rich repeat containing 45 0.021
Cd274 CD274 antigen 0.021
Clec2h C-type lectin domain family 2, member h 0.021
Pan2 PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae) 0.021
Ube2l6 ubiquitin-conjugating enzyme E2L 6 0.021
Akap8l A kinase (PRKA) anchor protein 8-like 0.021
Gvin1 GTPase, very large interferon inducible 1 0.020
Gypa glycophorin A 0.020
Ppp1r14d protein phosphatase 1, regulatory (inhibitor) subunit 14D 0.020
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.020
Pml promyelocytic leukemia 0.020
Oas2 2'-5' oligoadenylate synthetase 2 0.019
H2-Q6 histocompatibility 2, Q region locus 6 0.019
Vwa5a von Willebrand factor A domain containing 5A 0.019
Pdia6 protein disulfide isomerase associated 6 0.018
Irf7 interferon regulatory factor 7 0.018
Gm12185 predicted gene 12185 0.018
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism