IMP
Process View
mitotic centrosome separation
Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mitotic centrosome separation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Pafah1b1 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 | 1.000 | Worm | |
| Ndel1 | nuclear distribution gene E-like homolog 1 (A. nidulans) | 0.972 | ||
| Ccnb1 | cyclin B1 | 0.892 | ||
| Cdk1 | cyclin-dependent kinase 1 | 0.886 | ||
| Nde1 | nuclear distribution gene E homolog 1 (A nidulans) | 0.812 | Mouse | |
| Prc1 | protein regulator of cytokinesis 1 | 0.774 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.697 | ||
| Ccna2 | cyclin A2 | 0.587 | ||
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.528 | ||
| Kif20a | kinesin family member 20A | 0.473 | ||
| Racgap1 | Rac GTPase-activating protein 1 | 0.414 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.333 | ||
| Ckap2 | cytoskeleton associated protein 2 | 0.326 | ||
| Ccnb2 | cyclin B2 | 0.296 | ||
| Birc5 | baculoviral IAP repeat-containing 5 | 0.294 | ||
| Pcna | proliferating cell nuclear antigen | 0.282 | ||
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.251 | ||
| Cdca5 | cell division cycle associated 5 | 0.207 | ||
| Thoc4 | THO complex 4 | 0.197 | ||
| Kif11 | kinesin family member 11 | 0.179 | ||
| Kif22 | kinesin family member 22 | 0.168 | ||
| Pole2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.166 | ||
| Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.160 | ||
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.153 | ||
| Lmnb1 | lamin B1 | 0.149 | ||
| Aurka | aurora kinase A | 0.147 | ||
| H2afx | H2A histone family, member X | 0.143 | ||
| Kif2c | kinesin family member 2C | 0.142 | ||
| Kif4 | kinesin family member 4 | 0.141 | ||
| Uhrf1 | ubiquitin-like, containing PHD and RING finger domains, 1 | 0.140 | ||
| Kif23 | kinesin family member 23 | 0.134 | ||
| Dtl | denticleless homolog (Drosophila) | 0.133 | ||
| Dynll1 | dynein light chain LC8-type 1 | 0.132 | ||
| Ccnf | cyclin F | 0.130 | ||
| Gtse1 | G two S phase expressed protein 1 | 0.129 | ||
| Ccdc99 | coiled-coil domain containing 99 | 0.129 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.121 | ||
| Cdca8 | cell division cycle associated 8 | 0.118 | ||
| Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.093 | ||
| Trip13 | thyroid hormone receptor interactor 13 | 0.079 | ||
| Anln | anillin, actin binding protein | 0.079 | ||
| Ncaph | non-SMC condensin I complex, subunit H | 0.064 | ||
| Smc2 | structural maintenance of chromosomes 2 | 0.063 | ||
| Mcm2 | minichromosome maintenance deficient 2 mitotin (S. cerevisiae) | 0.062 | ||
| Fam64a | family with sequence similarity 64, member A | 0.056 | ||
| Aurkb | aurora kinase B | 0.052 | Fly | |
| Ttk | Ttk protein kinase | 0.052 | ||
| Mad2l1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.050 | ||
| Hmmr | hyaluronan mediated motility receptor (RHAMM) | 0.050 | ||
| Gsg2 | germ cell-specific gene 2 | 0.044 | ||
| Brca1 | breast cancer 1 | 0.041 | ||
| E2f8 | E2F transcription factor 8 | 0.041 | ||
| Tacc3 | transforming, acidic coiled-coil containing protein 3 | 0.039 | ||
| Ptma | prothymosin alpha | 0.037 | ||
| Tfdp1 | transcription factor Dp 1 | 0.036 | ||
| Cdca7 | cell division cycle associated 7 | 0.034 | ||
| Hnrnpab | heterogeneous nuclear ribonucleoprotein A/B | 0.033 | ||
| 2810417H13Rik | RIKEN cDNA 2810417H13 gene | 0.031 | ||
| Rrm2 | ribonucleotide reductase M2 | 0.031 | ||
| Fen1 | flap structure specific endonuclease 1 | 0.030 | ||
| Rcc1 | regulator of chromosome condensation 1 | 0.029 | ||
| Cdc45 | cell division cycle 45 homolog (S. cerevisiae) | 0.029 | ||
| Plk4 | polo-like kinase 4 (Drosophila) | 0.029 | ||
| Diap3 | diaphanous homolog 3 (Drosophila) | 0.029 | ||
| Cdc25c | cell division cycle 25 homolog C (S. pombe) | 0.028 | ||
| Hmgb2 | high mobility group box 2 | 0.028 | ||
| Mis18bp1 | MIS18 binding protein 1 | 0.027 | ||
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.027 | ||
| Exo1 | exonuclease 1 | 0.026 | ||
| Rrm1 | ribonucleotide reductase M1 | 0.025 | ||
| Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | 0.024 | ||
| Cks1b | CDC28 protein kinase 1b | 0.021 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.021 | ||
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.019 | ||
| Mki67 | antigen identified by monoclonal antibody Ki 67 | 0.019 | ||
| Aspm | asp (abnormal spindle)-like, microcephaly associated (Drosophila) | 0.018 | ||
| Clip1 | CAP-GLY domain containing linker protein 1 | 0.018 | ||
| Cenpf | centromere protein F | 0.017 | ||
| Macf1 | microtubule-actin crosslinking factor 1 | 0.017 | ||
| Mcm5 | minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 0.017 | ||
| Eif4a1 | eukaryotic translation initiation factor 4A1 | 0.017 | ||
| Lsm2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.016 | ||
| Ndc80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.016 | ||
| Cdca7l | cell division cycle associated 7 like | 0.016 | ||
| Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.015 | ||
| Nup35 | nucleoporin 35 | 0.015 | ||
| Rpa2 | replication protein A2 | 0.015 | ||
| Rfc3 | replication factor C (activator 1) 3 | 0.014 | ||
| Cenpa | centromere protein A | 0.014 | ||
| Tcf19 | transcription factor 19 | 0.013 | ||
| Eme1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.012 | ||
| Cks2 | CDC28 protein kinase regulatory subunit 2 | 0.012 | ||
| Ywhah | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.012 | ||
| Nxt1 | NTF2-related export protein 1 | 0.012 | ||
| Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.012 | ||
| Sae1 | SUMO1 activating enzyme subunit 1 | 0.012 | ||
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.011 | ||
| Tk1 | thymidine kinase 1 | 0.011 | ||
| Tmpo | thymopoietin | 0.011 | ||
| Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.011 | ||
| Trim59 | tripartite motif-containing 59 | 0.011 | ||
| Vmn1r65 | vomeronasal 1 receptor 65 | 0.011 | ||
| Mxd3 | Max dimerization protein 3 | 0.010 | ||
| Nuf2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.010 | ||
| Psmc3ip | proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein | 0.010 | ||
| Pola1 | polymerase (DNA directed), alpha 1 | 0.010 |