IMP
Process View
iris morphogenesis
The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "iris morphogenesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Foxc1 | forkhead box C1 | 0.997 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.977 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.917 | ||
| Shh | sonic hedgehog | 0.885 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.805 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.783 | Human | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.741 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.668 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.643 | ||
| Pax3 | paired box gene 3 | 0.642 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.540 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.441 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.399 | ||
| Jag1 | jagged 1 | 0.397 | ||
| Pax6 | paired box gene 6 | 0.391 | Human | |
| Foxc2 | forkhead box C2 | 0.368 | ||
| Sox2 | SRY-box containing gene 2 | 0.345 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.339 | ||
| Vegfa | vascular endothelial growth factor A | 0.330 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.242 | ||
| Rb1 | retinoblastoma 1 | 0.237 | ||
| Egfr | epidermal growth factor receptor | 0.215 | ||
| Rxra | retinoid X receptor alpha | 0.174 | ||
| Rarb | retinoic acid receptor, beta | 0.156 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.156 | ||
| Fgf8 | fibroblast growth factor 8 | 0.146 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.126 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.123 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.119 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.118 | ||
| Foxg1 | forkhead box G1 | 0.089 | ||
| Tbx1 | T-box 1 | 0.085 | ||
| Sox9 | SRY-box containing gene 9 | 0.082 | ||
| Sox11 | SRY-box containing gene 11 | 0.079 | ||
| Meox2 | mesenchyme homeobox 2 | 0.078 | ||
| Mab21l1 | mab-21-like 1 (C. elegans) | 0.078 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.073 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.072 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.059 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.059 | ||
| Pax2 | paired box gene 2 | 0.057 | ||
| Fuz | fuzzy homolog (Drosophila) | 0.056 | ||
| Gata4 | GATA binding protein 4 | 0.053 | ||
| Foxe3 | forkhead box E3 | 0.049 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.048 | ||
| Tbx3 | T-box 3 | 0.046 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.042 | ||
| Neurod1 | neurogenic differentiation 1 | 0.039 | ||
| Tbx4 | T-box 4 | 0.035 | ||
| Rarg | retinoic acid receptor, gamma | 0.034 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.034 | ||
| Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.034 | ||
| Nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.032 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.031 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.029 | ||
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.028 | ||
| Psen1 | presenilin 1 | 0.026 | ||
| Foxf2 | forkhead box F2 | 0.025 | ||
| Msx2 | homeobox, msh-like 2 | 0.025 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.024 | ||
| Fgf10 | fibroblast growth factor 10 | 0.024 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.023 | ||
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.023 | ||
| Mks1 | Meckel syndrome, type 1 | 0.020 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.020 | ||
| Mitf | microphthalmia-associated transcription factor | 0.020 | ||
| Smo | smoothened homolog (Drosophila) | 0.020 | ||
| Myf5 | myogenic factor 5 | 0.019 | ||
| Ccdc39 | coiled-coil domain containing 39 | 0.019 | ||
| Trp53 | transformation related protein 53 | 0.019 | ||
| Sox4 | SRY-box containing gene 4 | 0.018 | ||
| Efnb2 | ephrin B2 | 0.018 | ||
| Gja1 | gap junction protein, alpha 1 | 0.017 | ||
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.017 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.016 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.015 | ||
| Dnahc11 | dynein, axonemal, heavy chain 11 | 0.015 | ||
| Ece1 | endothelin converting enzyme 1 | 0.015 | ||
| Ntf3 | neurotrophin 3 | 0.015 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.014 | ||
| Acvr1 | activin A receptor, type 1 | 0.013 | ||
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.013 | ||
| Insm1 | insulinoma-associated 1 | 0.012 | ||
| Prdm16 | PR domain containing 16 | 0.011 | ||
| Gsc | goosecoid homeobox | 0.011 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.011 | ||
| Dlx5 | distal-less homeobox 5 | 0.011 | ||
| Rara | retinoic acid receptor, alpha | 0.011 |