IMP

Process View

Mus musculus

1 genes annotated in mouse

regulation of sphingolipid biosynthetic process

Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of sphingolipid biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of sphingolipid biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Mapkap1	mitogen-activated protein kinase associated protein 1	0.774
Rptor	regulatory associated protein of MTOR, complex 1	0.611
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.505
Rictor	RPTOR independent companion of MTOR, complex 2	0.499
Dusp1	dual specificity phosphatase 1	0.320
Thbs1	thrombospondin 1	0.283
Tnc	tenascin C	0.237
Lox	lysyl oxidase	0.207
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.197
Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)	0.185
Amotl2	angiomotin-like 2	0.176
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.134
F3	coagulation factor III	0.117
Blnk	B-cell linker	0.088
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.079
Thbs2	thrombospondin 2	0.077
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.074
Fos	FBJ osteosarcoma oncogene	0.072
0610007P14Rik	RIKEN cDNA 0610007P14 gene	0.071
Errfi1	ERBB receptor feedback inhibitor 1	0.071
Rpa3	replication protein A3	0.071
Col5a2	collagen, type V, alpha 2	0.067
Fstl1	follistatin-like 1	0.066
Col6a1	collagen, type VI, alpha 1	0.062
Col8a1	collagen, type VIII, alpha 1	0.061
Prrx1	paired related homeobox 1	0.060
Telo2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.055
Gli2	GLI-Kruppel family member GLI2	0.055
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.055
Prss23	protease, serine, 23	0.050
Igh	immunoglobulin heavy chain complex	0.047
Col5a1	collagen, type V, alpha 1	0.045
Tll1	tolloid-like	0.044
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.041
Fgfr3	fibroblast growth factor receptor 3	0.039
Bcl6	B-cell leukemia/lymphoma 6	0.039
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.037
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.037
Fbln2	fibulin 2	0.036
Klf4	Kruppel-like factor 4 (gut)	0.035
Rpe	ribulose-5-phosphate-3-epimerase	0.034
Fgfrl1	fibroblast growth factor receptor-like 1	0.033
Col1a1	collagen, type I, alpha 1	0.030
Col3a1	collagen, type III, alpha 1	0.030
Tmx1	thioredoxin-related transmembrane protein 1	0.029
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.029
Col4a1	collagen, type IV, alpha 1	0.029
Pxmp3	peroxisomal membrane protein 3	0.029
Mfap5	microfibrillar associated protein 5	0.029
Ltbp1	latent transforming growth factor beta binding protein 1	0.029
Creb3l1	cAMP responsive element binding protein 3-like 1	0.028
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.026
Plat	plasminogen activator, tissue	0.026
Prrx2	paired related homeobox 2	0.025
Tfpi2	tissue factor pathway inhibitor 2	0.025
Pthlh	parathyroid hormone-like peptide	0.024
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.024
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.024
Klf6	Kruppel-like factor 6	0.024
Cyb5r4	cytochrome b5 reductase 4	0.024
Sox9	SRY-box containing gene 9	0.024
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.023
Tmem33	transmembrane protein 33	0.023
Fkbp10	FK506 binding protein 10	0.023
Ebag9	estrogen receptor-binding fragment-associated gene 9	0.022
Hbegf	heparin-binding EGF-like growth factor	0.021
Ptgs2	prostaglandin-endoperoxide synthase 2	0.021
Nat2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.021
Vamp7	vesicle-associated membrane protein 7	0.020
Col4a5	collagen, type IV, alpha 5	0.020
Wwtr1	WW domain containing transcription regulator 1	0.019
Osmr	oncostatin M receptor	0.019
Timp1	tissue inhibitor of metalloproteinase 1	0.019
Zeb1	zinc finger E-box binding homeobox 1	0.019
Adm	adrenomedullin	0.018
Vasn	vasorin	0.018
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.018
Kdelr3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.017
Ebp	phenylalkylamine Ca2+ antagonist (emopamil) binding protein	0.017
Wisp1	WNT1 inducible signaling pathway protein 1	0.017	Mouse
Tagln	transgelin	0.016
Sft2d1	SFT2 domain containing 1	0.016
Psmd10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.016
Col15a1	collagen, type XV, alpha 1	0.016
Ldb3	LIM domain binding 3	0.016
Hspa1b	heat shock protein 1B	0.016
Col6a3	collagen, type VI, alpha 3	0.016
Tmem128	transmembrane protein 128	0.015
Ormdl2	ORM1-like 2 (S. cerevisiae)	0.015	Yeast
Tgfb2	transforming growth factor, beta 2	0.015
Col12a1	collagen, type XII, alpha 1	0.015
Kcne4	potassium voltage-gated channel, Isk-related subfamily, gene 4	0.015
Ier3	immediate early response 3	0.015
Gpr133	G protein-coupled receptor 133	0.015
Chac2	ChaC, cation transport regulator homolog 2 (E. coli)	0.015
Rhbdf1	rhomboid family 1 (Drosophila)	0.015
Rps6	ribosomal protein S6	0.015
Egr2	early growth response 2	0.015
Col1a2	collagen, type I, alpha 2	0.014
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.014
Pdpn	podoplanin	0.014
Samd4	sterile alpha motif domain containing 4	0.014
Frmd6	FERM domain containing 6	0.014
Cyr61	cysteine rich protein 61	0.014
Figf	c-fos induced growth factor	0.013
Hrsp12	heat-responsive protein 12	0.013
Ltbp2	latent transforming growth factor beta binding protein 2	0.013
Egr1	early growth response 1	0.013
Lpar1	lysophosphatidic acid receptor 1	0.013
Manf	mesencephalic astrocyte-derived neurotrophic factor	0.013
Lypla1	lysophospholipase 1	0.013
Acta2	actin, alpha 2, smooth muscle, aorta	0.013
Cnn1	calponin 1	0.013
Ctsk	cathepsin K	0.012
1700123O20Rik	RIKEN cDNA 1700123O20 gene	0.012
Jun	Jun oncogene	0.012
Fgf18	fibroblast growth factor 18	0.012
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.012
Col6a2	collagen, type VI, alpha 2	0.012
Phldb2	pleckstrin homology-like domain, family B, member 2	0.012
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.012
Jtb	jumping translocation breakpoint	0.012
Tgds	TDP-glucose 4,6-dehydratase	0.012
Psmd5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	0.012
Postn	periostin, osteoblast specific factor	0.012
Cxcr7	chemokine (C-X-C motif) receptor 7	0.012
Fgf7	fibroblast growth factor 7	0.012
Tm4sf1	transmembrane 4 superfamily member 1	0.012
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.011
Cd40	CD40 antigen	0.011
Timp3	tissue inhibitor of metalloproteinase 3	0.011
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.011
Plk2	polo-like kinase 2 (Drosophila)	0.011
Hr	hairless	0.011
Hspa1a	heat shock protein 1A	0.011
Dysf	dysferlin	0.011
Ctgf	connective tissue growth factor	0.011	Mouse
AI314976	expressed sequence AI314976	0.011
Polr3k	polymerase (RNA) III (DNA directed) polypeptide K	0.011
Adamts5	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)	0.011
Dpysl3	dihydropyrimidinase-like 3	0.010