IMP

Process View

Mus musculus

9 genes annotated in mouse

response to peptidoglycan

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to peptidoglycan"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to peptidoglycan" (in gray)

Name	Description	Probability	Func Analog Organism
Tlr4	toll-like receptor 4	0.998	Mouse
Myd88	myeloid differentiation primary response gene 88	0.996
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.844
Cd44	CD44 antigen	0.697
Nlrp3	NLR family, pyrin domain containing 3	0.656	Mouse
Mefv	Mediterranean fever	0.519
Traf6	TNF receptor-associated factor 6	0.504
Irak4	interleukin-1 receptor-associated kinase 4	0.400
Clec4n	C-type lectin domain family 4, member n	0.355
Ccl2	chemokine (C-C motif) ligand 2	0.326
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.210
Il1r1	interleukin 1 receptor, type I	0.176
Msr1	macrophage scavenger receptor 1	0.167
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.152
Irg1	immunoresponsive gene 1	0.148
Cd14	CD14 antigen	0.136
Il10	interleukin 10	0.127
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.120
Ticam1	toll-like receptor adaptor molecule 1	0.118
Fcgr4	Fc receptor, IgG, low affinity IV	0.116
Siglece	sialic acid binding Ig-like lectin E	0.116
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.112
Cd300ld	CD300 molecule-like family member d	0.102
Fpr1	formyl peptide receptor 1	0.096	Mouse
Casp1	caspase 1	0.092
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.081
Il1b	interleukin 1 beta	0.080
Pycard	PYD and CARD domain containing	0.077
Irak3	interleukin-1 receptor-associated kinase 3	0.074
Cd33	CD33 antigen	0.068
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.067
Clec4d	C-type lectin domain family 4, member d	0.065
Plau	plasminogen activator, urokinase	0.052
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.050
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.046
Trem3	triggering receptor expressed on myeloid cells 3	0.043
Il1rn	interleukin 1 receptor antagonist	0.040
Mb	myoglobin	0.038
Tnf	tumor necrosis factor	0.036
Il1f9	interleukin 1 family, member 9	0.036
Clec4e	C-type lectin domain family 4, member e	0.035
Il1a	interleukin 1 alpha	0.034
Nos2	nitric oxide synthase 2, inducible	0.034
Nfam1	Nfat activating molecule with ITAM motif 1	0.032
Irak1	interleukin-1 receptor-associated kinase 1	0.032
Ccr1	chemokine (C-C motif) receptor 1	0.031
Fpr2	formyl peptide receptor 2	0.029	Mouse
Aoah	acyloxyacyl hydrolase	0.028
Mmp8	matrix metallopeptidase 8	0.027
Ticam2	toll-like receptor adaptor molecule 2	0.026
Ccr2	chemokine (C-C motif) receptor 2	0.025
Btk	Bruton agammaglobulinemia tyrosine kinase	0.025
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.021
Pilra	paired immunoglobin-like type 2 receptor alpha	0.020
Tcfec	transcription factor EC	0.020
F7	coagulation factor VII	0.020
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.019
Cblb	Casitas B-lineage lymphoma b	0.019
Gpr35	G protein-coupled receptor 35	0.017
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.017
Fpr3	formyl peptide receptor 3	0.017	Mouse
Cd180	CD180 antigen	0.017	Mouse
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.017
Tifa	TRAF-interacting protein with forkhead-associated domain	0.016
Clec7a	C-type lectin domain family 7, member a	0.016
Aim2	absent in melanoma 2	0.016
C130050O18Rik	RIKEN cDNA C130050O18 gene	0.016
Ccl3	chemokine (C-C motif) ligand 3	0.016
Ly96	lymphocyte antigen 96	0.015
Clec5a	C-type lectin domain family 5, member a	0.015
Mmp9	matrix metallopeptidase 9	0.015
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.014
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.014
Cd300lf	CD300 antigen like family member F	0.014	Mouse
Gbp5	guanylate binding protein 5	0.014
Slfn4	schlafen 4	0.014
Fcgr1	Fc receptor, IgG, high affinity I	0.014
Marco	macrophage receptor with collagenous structure	0.012
Cd84	CD84 antigen	0.012
Tbxas1	thromboxane A synthase 1, platelet	0.012
Tlr8	toll-like receptor 8	0.012	Mouse
Cysltr1	cysteinyl leukotriene receptor 1	0.012
Hcst	hematopoietic cell signal transducer	0.011
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.011
B430306N03Rik	RIKEN cDNA B430306N03 gene	0.011
F10	coagulation factor X	0.011
Slamf8	SLAM family member 8	0.011
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.011
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.011
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.010
Lair1	leukocyte-associated Ig-like receptor 1	0.010
Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	0.010
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.010
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.010