IMP
Process View
paracrine signaling
The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "paracrine signaling"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Mapk14 | mitogen-activated protein kinase 14 | 0.982 | Fly | |
| Mapk11 | mitogen-activated protein kinase 11 | 0.969 | Fly | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.530 | ||
| Phlda3 | pleckstrin homology-like domain, family A, member 3 | 0.247 | ||
| Mapkapk2 | MAP kinase-activated protein kinase 2 | 0.225 | ||
| Kdr | kinase insert domain protein receptor | 0.220 | ||
| Mknk2 | MAP kinase-interacting serine/threonine kinase 2 | 0.110 | ||
| Itga3 | integrin alpha 3 | 0.076 | ||
| Apoe | apolipoprotein E | 0.073 | ||
| Flt4 | FMS-like tyrosine kinase 4 | 0.073 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.072 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.062 | ||
| Lama5 | laminin, alpha 5 | 0.047 | ||
| Fzd4 | frizzled homolog 4 (Drosophila) | 0.046 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.046 | ||
| Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.045 | ||
| Atf2 | activating transcription factor 2 | 0.044 | ||
| Fbln1 | fibulin 1 | 0.043 | ||
| Mapk12 | mitogen-activated protein kinase 12 | 0.041 | Fly | |
| Egln1 | EGL nine homolog 1 (C. elegans) | 0.040 | ||
| Plxnd1 | plexin D1 | 0.039 | ||
| Hbegf | heparin-binding EGF-like growth factor | 0.036 | ||
| Mknk1 | MAP kinase-interacting serine/threonine kinase 1 | 0.031 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.031 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.029 | ||
| Pdgfc | platelet-derived growth factor, C polypeptide | 0.028 | ||
| Cd151 | CD151 antigen | 0.028 | ||
| Atp2a2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.028 | ||
| Mapk9 | mitogen-activated protein kinase 9 | 0.026 | ||
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.025 | ||
| Gaa | glucosidase, alpha, acid | 0.023 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.023 | ||
| Spry4 | sprouty homolog 4 (Drosophila) | 0.023 | ||
| Prkce | protein kinase C, epsilon | 0.022 | ||
| Kcnh2 | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 0.021 | ||
| Map2k3 | mitogen-activated protein kinase kinase 3 | 0.021 | ||
| Vegfa | vascular endothelial growth factor A | 0.021 | Mouse | |
| Htra1 | HtrA serine peptidase 1 | 0.020 | ||
| Acvr1 | activin A receptor, type 1 | 0.020 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.020 | ||
| Macrod1 | MACRO domain containing 1 | 0.020 | ||
| Pcbp4 | poly(rC) binding protein 4 | 0.019 | ||
| Spint1 | serine protease inhibitor, Kunitz type 1 | 0.019 | ||
| Src | Rous sarcoma oncogene | 0.019 | ||
| Jag2 | jagged 2 | 0.019 | ||
| Gys1 | glycogen synthase 1, muscle | 0.019 | ||
| Aco1 | aconitase 1 | 0.018 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.018 | ||
| Cyhr1 | cysteine and histidine rich 1 | 0.018 | ||
| Phldb2 | pleckstrin homology-like domain, family B, member 2 | 0.018 | ||
| Tspan12 | tetraspanin 12 | 0.018 | ||
| Sox18 | SRY-box containing gene 18 | 0.018 | ||
| Aldh6a1 | aldehyde dehydrogenase family 6, subfamily A1 | 0.017 | ||
| Grsf1 | G-rich RNA sequence binding factor 1 | 0.017 | ||
| Nrp1 | neuropilin 1 | 0.017 | ||
| Met | met proto-oncogene | 0.017 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.016 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.016 | ||
| Wt1 | Wilms tumor 1 homolog | 0.016 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.015 | ||
| Esrp1 | epithelial splicing regulatory protein 1 | 0.015 | ||
| Jag1 | jagged 1 | 0.015 | ||
| Plcb3 | phospholipase C, beta 3 | 0.015 | ||
| She | src homology 2 domain-containing transforming protein E | 0.015 | ||
| Snta1 | syntrophin, acidic 1 | 0.015 | ||
| Ece1 | endothelin converting enzyme 1 | 0.015 | ||
| Cdh1 | cadherin 1 | 0.015 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.014 | ||
| Sfn | stratifin | 0.014 | ||
| Pfkm | phosphofructokinase, muscle | 0.014 | ||
| Thbd | thrombomodulin | 0.014 | ||
| Emp2 | epithelial membrane protein 2 | 0.014 | ||
| Fstl3 | follistatin-like 3 | 0.014 | ||
| Trp53 | transformation related protein 53 | 0.013 | ||
| Krt19 | keratin 19 | 0.013 | ||
| Des | desmin | 0.013 | ||
| Pkdcc | protein kinase domain containing, cytoplasmic | 0.013 | ||
| Ntf3 | neurotrophin 3 | 0.013 | ||
| Irs1 | insulin receptor substrate 1 | 0.013 | ||
| Yap1 | yes-associated protein 1 | 0.012 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.012 | ||
| Lama4 | laminin, alpha 4 | 0.012 | ||
| St14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.012 | ||
| Wnt4 | wingless-related MMTV integration site 4 | 0.012 | ||
| Mark4 | MAP/microtubule affinity-regulating kinase 4 | 0.012 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.012 | ||
| Dmpk | dystrophia myotonica-protein kinase | 0.012 | ||
| Fech | ferrochelatase | 0.012 | ||
| Casp12 | caspase 12 | 0.012 | ||
| Akap2 | A kinase (PRKA) anchor protein 2 | 0.012 | ||
| Ctnnbip1 | catenin beta interacting protein 1 | 0.011 | ||
| Mib1 | mindbomb homolog 1 (Drosophila) | 0.011 | ||
| Jup | junction plakoglobin | 0.011 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.011 | ||
| P4ha2 | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide | 0.011 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.011 | ||
| Hif1an | hypoxia-inducible factor 1, alpha subunit inhibitor | 0.011 | ||
| Ugp2 | UDP-glucose pyrophosphorylase 2 | 0.011 | ||
| Hspb8 | heat shock protein 8 | 0.011 | ||
| Tnks1bp1 | tankyrase 1 binding protein 1 | 0.011 | ||
| Arhgap8 | Rho GTPase activating protein 8 | 0.011 | ||
| Mcart1 | mitochondrial carrier triple repeat 1 | 0.011 | ||
| Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.011 | ||
| Nfic | nuclear factor I/C | 0.011 | ||
| Rcan1 | regulator of calcineurin 1 | 0.010 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.010 | ||
| Eno3 | enolase 3, beta muscle | 0.010 | ||
| Cxcr7 | chemokine (C-X-C motif) receptor 7 | 0.010 |