IMP

Process View

Mus musculus

6 genes annotated in mouse

erythrocyte maturation

A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "erythrocyte maturation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "erythrocyte maturation" (in gray)

Name	Description	Probability	Func Analog Organism
Spna1	spectrin alpha 1	0.999
Ank1	ankyrin 1, erythroid	0.998
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.998
Hbb-b1	hemoglobin, beta adult major chain	0.998
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.997
Shh	sonic hedgehog	0.995
Otx2	orthodenticle homolog 2 (Drosophila)	0.985
Hand2	heart and neural crest derivatives expressed transcript 2	0.966	Mouse
Msx1	homeobox, msh-like 1	0.939
Neurod4	neurogenic differentiation 4	0.933	Mouse
Epor	erythropoietin receptor	0.909
Neurog2	neurogenin 2	0.905	Mouse
Pax6	paired box gene 6	0.884
Neurod1	neurogenic differentiation 1	0.874	Mouse
Spnb1	spectrin beta 1	0.874
Isl1	ISL1 transcription factor, LIM/homeodomain	0.863
Gata1	GATA binding protein 1	0.809
Hand1	heart and neural crest derivatives expressed transcript 1	0.788	Mouse
Tcfap2a	transcription factor AP-2, alpha	0.785
Hbb-b2	hemoglobin, beta adult minor chain	0.704
Fos	FBJ osteosarcoma oncogene	0.680
Exoc6	exocyst complex component 6	0.582
Gata4	GATA binding protein 4	0.561
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.535
Eya1	eyes absent 1 homolog (Drosophila)	0.518
Onecut1	one cut domain, family member 1	0.511
Pax3	paired box gene 3	0.443
Add2	adducin 2 (beta)	0.386
Gli3	GLI-Kruppel family member GLI3	0.359
Gpr50	G-protein-coupled receptor 50	0.347
Dlx2	distal-less homeobox 2	0.329
Pbx1	pre B-cell leukemia transcription factor 1	0.329
Gsc	goosecoid homeobox	0.320
Prrx1	paired related homeobox 1	0.320
Hoxa1	homeobox A1	0.317
Hoxd13	homeobox D13	0.314
Dlx5	distal-less homeobox 5	0.312
Foxc2	forkhead box C2	0.300
Ptf1a	pancreas specific transcription factor, 1a	0.298	Mouse
Klf1	Kruppel-like factor 1 (erythroid)	0.298
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.294
Gypa	glycophorin A	0.269
Nhlh1	nescient helix loop helix 1	0.263	Mouse
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.260
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.254
Mecom	MDS1 and EVI1 complex locus	0.235
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.231
Tal1	T-cell acute lymphocytic leukemia 1	0.228
Ahsp	alpha hemoglobin stabilizing protein	0.228
Insm1	insulinoma-associated 1	0.220
Msx2	homeobox, msh-like 2	0.215
Hoxb1	homeobox B1	0.205
Efna2	ephrin A2	0.200
Fgf15	fibroblast growth factor 15	0.185
Rhag	Rhesus blood group-associated A glycoprotein	0.184
Mab21l2	mab-21-like 2 (C. elegans)	0.181
Sox11	SRY-box containing gene 11	0.181
Pklr	pyruvate kinase liver and red blood cell	0.177
Steap3	STEAP family member 3	0.174
Trim10	tripartite motif-containing 10	0.169
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.157
Pdx1	pancreatic and duodenal homeobox 1	0.137
Pax9	paired box gene 9	0.136
Hoxd3	homeobox D3	0.128
Foxd2	forkhead box D2	0.126
Rhob	ras homolog gene family, member B	0.119
Dusp1	dual specificity phosphatase 1	0.116
Slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.114
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.108
Chrd	chordin	0.106
Alx3	aristaless-like homeobox 3	0.106
Tgfb2	transforming growth factor, beta 2	0.100
Sox9	SRY-box containing gene 9	0.098
Prrx2	paired related homeobox 2	0.097
Foxc1	forkhead box C1	0.097
Zeb1	zinc finger E-box binding homeobox 1	0.097
Foxg1	forkhead box G1	0.096
Tlx3	T-cell leukemia, homeobox 3	0.094
Rhd	Rh blood group, D antigen	0.087
Hif3a	hypoxia inducible factor 3, alpha subunit	0.082
Sox2	SRY-box containing gene 2	0.082
Hoxa2	homeobox A2	0.081
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.075
En1	engrailed 1	0.075
Gli2	GLI-Kruppel family member GLI2	0.073
Hoxd1	homeobox D1	0.072
Gbx2	gastrulation brain homeobox 2	0.072
Prox1	prospero-related homeobox 1	0.070
Pitx1	paired-like homeodomain transcription factor 1	0.068
Jag1	jagged 1	0.068
Klf6	Kruppel-like factor 6	0.066	Mouse
Shox2	short stature homeobox 2	0.064
Neurog3	neurogenin 3	0.063	Mouse
Bmp7	bone morphogenetic protein 7	0.063
Btg2	B-cell translocation gene 2, anti-proliferative	0.062
Col9a1	collagen, type IX, alpha 1	0.059
Ebf2	early B-cell factor 2	0.057
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.056
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.055
Hoxc5	homeobox C5	0.054
Bmp4	bone morphogenetic protein 4	0.054
Meox2	mesenchyme homeobox 2	0.054
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.054
Lhx9	LIM homeobox protein 9	0.054
Pou3f2	POU domain, class 3, transcription factor 2	0.052
Lhx5	LIM homeobox protein 5	0.052
Pou4f2	POU domain, class 4, transcription factor 2	0.050
Prph	peripherin	0.050
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.049
Srrm4	serine/arginine repetitive matrix 4	0.045
Ebf3	early B-cell factor 3	0.045
Tbx1	T-box 1	0.045
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.044
Fgf4	fibroblast growth factor 4	0.044
Phox2b	paired-like homeobox 2b	0.043
Hoxd11	homeobox D11	0.042
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.041
Dlx6	distal-less homeobox 6	0.041
Zic2	zinc finger protein of the cerebellum 2	0.041
Sall3	sal-like 3 (Drosophila)	0.039
Foxd1	forkhead box D1	0.039
Pitx3	paired-like homeodomain transcription factor 3	0.038
Ermap	erythroblast membrane-associated protein	0.038
Gp9	glycoprotein 9 (platelet)	0.037
Sox1	SRY-box containing gene 1	0.037
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.037
Dcc	deleted in colorectal carcinoma	0.037
Epb4.2	erythrocyte protein band 4.2	0.035
Erbb2ip	Erbb2 interacting protein	0.034
Hoxb4	homeobox B4	0.033
Foxa2	forkhead box A2	0.033
Nkx3-2	NK3 homeobox 2	0.033
Uncx	UNC homeobox	0.032
Hfe	hemochromatosis	0.032
Pax2	paired box gene 2	0.031
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.031
Evx1	even skipped homeotic gene 1 homolog	0.031
Hoxa5	homeobox A5	0.031
Slc38a5	solute carrier family 38, member 5	0.031
Adra2b	adrenergic receptor, alpha 2b	0.030
Gata6	GATA binding protein 6	0.030
Hoxc8	homeobox C8	0.029
Lmx1a	LIM homeobox transcription factor 1 alpha	0.029
Runx2	runt related transcription factor 2	0.028
Tal2	T-cell acute lymphocytic leukemia 2	0.028	Mouse
Nfe2	nuclear factor, erythroid derived 2	0.027
Gdf11	growth differentiation factor 11	0.027
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.026
Hmga2	high mobility group AT-hook 2	0.026
Tlx2	T-cell leukemia, homeobox 2	0.026
Foxh1	forkhead box H1	0.026
Gfi1b	growth factor independent 1B	0.026
Jun	Jun oncogene	0.025
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.025
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.025
Hoxa10	homeobox A10	0.024
Hoxc6	homeobox C6	0.024
Pitx2	paired-like homeodomain transcription factor 2	0.024
Foxo4	forkhead box O4	0.024
Zswim6	zinc finger, SWIM domain containing 6	0.024
En2	engrailed 2	0.023
Fgf8	fibroblast growth factor 8	0.023
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.023
Gnrh1	gonadotropin releasing hormone 1	0.023
Lef1	lymphoid enhancer binding factor 1	0.023
Alx4	aristaless-like homeobox 4	0.022
Ttc7	tetratricopeptide repeat domain 7	0.022
Ednra	endothelin receptor type A	0.022
Fbn2	fibrillin 2	0.022
Bmp2	bone morphogenetic protein 2	0.022
Dlx1	distal-less homeobox 1	0.022
Ntf3	neurotrophin 3	0.021
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.021
Foxd4	forkhead box D4	0.021
Tcf15	transcription factor 15	0.020	Mouse
Hoxd10	homeobox D10	0.020
Hoxa11	homeobox A11	0.020
Emx1	empty spiracles homolog 1 (Drosophila)	0.020
Matn3	matrilin 3	0.020
Magel2	melanoma antigen, family L, 2	0.020
D530037H12Rik	RIKEN cDNA D530037H12 gene	0.020
Klf4	Kruppel-like factor 4 (gut)	0.020	Mouse
Dcx	doublecortin	0.020
Tcfap2c	transcription factor AP-2, gamma	0.020
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.020
Cdca3	cell division cycle associated 3	0.019
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.019
Sim2	single-minded homolog 2 (Drosophila)	0.019
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.019
Bcl10	B-cell leukemia/lymphoma 10	0.019
Plac1	placental specific protein 1	0.019
Tgfbr2	transforming growth factor, beta receptor II	0.019
Emid2	EMI domain containing 2	0.018
Hoxa13	homeobox A13	0.018
Tbx20	T-box 20	0.018
Sim1	single-minded homolog 1 (Drosophila)	0.018
Hoxa9	homeobox A9	0.018
Apoa1	apolipoprotein A-I	0.018
Zic1	zinc finger protein of the cerebellum 1	0.017
Vsx2	visual system homeobox 2	0.017
Tcf4	transcription factor 4	0.017
Hoxc4	homeobox C4	0.017
Hoxa4	homeobox A4	0.017
Cel	carboxyl ester lipase	0.016
Tacr2	tachykinin receptor 2	0.016
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.016
Arx	aristaless related homeobox	0.016
Tcf21	transcription factor 21	0.016
Mpo	myeloperoxidase	0.016
Evx2	even skipped homeotic gene 2 homolog	0.016
Myog	myogenin	0.015
Dlk1	delta-like 1 homolog (Drosophila)	0.015
Zcchc11	zinc finger, CCHC domain containing 11	0.015
Uros	uroporphyrinogen III synthase	0.014
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.014
Oc90	otoconin 90	0.014
Glra1	glycine receptor, alpha 1 subunit	0.014
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.014
Hoxb5	homeobox B5	0.014
Sall4	sal-like 4 (Drosophila)	0.014
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.014
Irf2bp2	interferon regulatory factor 2 binding protein 2	0.014
Zbtb37	zinc finger and BTB domain containing 37	0.014
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.014
Alx1	ALX homeobox 1	0.014
Crb2	crumbs homolog 2 (Drosophila)	0.014
Mcl1	myeloid cell leukemia sequence 1	0.014
Epx	eosinophil peroxidase	0.013
Dab1	disabled homolog 1 (Drosophila)	0.013
Nkx6-1	NK6 homeobox 1	0.013
Has2	hyaluronan synthase 2	0.013
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.013
Hba-a2	hemoglobin alpha, adult chain 2	0.013
Gcm1	glial cells missing homolog 1 (Drosophila)	0.013
Wdr19	WD repeat domain 19	0.013
Klf7	Kruppel-like factor 7 (ubiquitous)	0.013	Mouse
Pou4f3	POU domain, class 4, transcription factor 3	0.013
Sgk1	serum/glucocorticoid regulated kinase 1	0.012
Bptf	bromodomain PHD finger transcription factor	0.012
T	brachyury	0.012
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.012
Hmx1	H6 homeobox 1	0.012
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.012
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.012
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.012
Myt1	myelin transcription factor 1	0.011
Ush1g	Usher syndrome 1G homolog (human)	0.011
Ep400	E1A binding protein p400	0.011
Dok1	docking protein 1	0.011
Tcf3	transcription factor 3	0.011
Dsg4	desmoglein 4	0.011
Klf2	Kruppel-like factor 2 (lung)	0.011
Cp	ceruloplasmin	0.011
Atoh7	atonal homolog 7 (Drosophila)	0.011	Mouse
Lhx3	LIM homeobox protein 3	0.011
Gpx5	glutathione peroxidase 5	0.011
Galr1	galanin receptor 1	0.011
Irs2	insulin receptor substrate 2	0.011
Kel	Kell blood group	0.011
Efna5	ephrin A5	0.011
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.011	Zebrafish
Zic4	zinc finger protein of the cerebellum 4	0.010
Hemgn	hemogen	0.010
Hes2	hairy and enhancer of split 2 (Drosophila)	0.010
Myod1	myogenic differentiation 1	0.010
Hoxd4	homeobox D4	0.010
Gna13	guanine nucleotide binding protein, alpha 13	0.010
Bnc1	basonuclin 1	0.010
Mn1	meningioma 1	0.010
Ngp	neutrophilic granule protein	0.010