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Mus musculus

4 genes annotated in mouse

dopamine uptake involved in synaptic transmission

The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dopamine uptake involved in synaptic transmission"

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Name	Description	Probability	Func Analog Organism
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.994
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.261
Oprm1	opioid receptor, mu 1	0.218
Lhx3	LIM homeobox protein 3	0.168
Drd1a	dopamine receptor D1A	0.159
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.158
Nos1	nitric oxide synthase 1, neuronal	0.112
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.099
Psmb3	proteasome (prosome, macropain) subunit, beta type 3	0.080
Thrb	thyroid hormone receptor beta	0.067
Txndc8	thioredoxin domain containing 8	0.064
Prop1	paired like homeodomain factor 1	0.064
Keg1	kidney expressed gene 1	0.054
Mrps21	mitochondrial ribosomal protein S21	0.048
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.047
Prl	prolactin	0.045
Cd151	CD151 antigen	0.044
Resp18	regulated endocrine-specific protein 18	0.043
Pax4	paired box gene 4	0.043
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.043
Drd2	dopamine receptor D2	0.042
Crhr1	corticotropin releasing hormone receptor 1	0.041
Col4a4	collagen, type IV, alpha 4	0.040
Pitx3	paired-like homeodomain transcription factor 3	0.040
Emx1	empty spiracles homolog 1 (Drosophila)	0.039
Lama5	laminin, alpha 5	0.038
Cml5	camello-like 5	0.038	Mouse
Wt1	Wilms tumor 1 homolog	0.037
Trh	thyrotropin releasing hormone	0.037
Nat8	N-acetyltransferase 8 (GCN5-related, putative)	0.036	Mouse
En1	engrailed 1	0.036
Nphs2	nephrosis 2 homolog, podocin (human)	0.035
Col4a3	collagen, type IV, alpha 3	0.034
Znrf4	zinc and ring finger 4	0.033
Ilk	integrin linked kinase	0.033
Mfn2	mitofusin 2	0.032
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.032
Dlg4	discs, large homolog 4 (Drosophila)	0.032
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.031
Cnr1	cannabinoid receptor 1 (brain)	0.031
Kl	klotho	0.031
Pgr	progesterone receptor	0.030
Acot4	acyl-CoA thioesterase 4	0.030
Slc2a5	solute carrier family 2 (facilitated glucose transporter), member 5	0.028
Pgc	progastricsin (pepsinogen C)	0.028
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.027
Ptgfr	prostaglandin F receptor	0.026
Hyal3	hyaluronoglucosaminidase 3	0.025
H2-Ke2	H2-K region expressed gene 2	0.025
Ubxn10	UBX domain protein 10	0.025
Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	0.024
Gcgr	glucagon receptor	0.024
Fam164c	family with sequence similarity 164, member C	0.024
Cckbr	cholecystokinin B receptor	0.024
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.024
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.024
Srcin1	SRC kinase signaling inhibitor 1	0.023
Gypa	glycophorin A	0.023
Mrpl11	mitochondrial ribosomal protein L11	0.023
Hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.023
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.023
Romo1	reactive oxygen species modulator 1	0.023
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.022
Epha8	Eph receptor A8	0.022
Odf1	outer dense fiber of sperm tails 1	0.022
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.022
Ache	acetylcholinesterase	0.022
Psmb6	proteasome (prosome, macropain) subunit, beta type 6	0.022
Zfp92	zinc finger protein 92	0.021
Tshr	thyroid stimulating hormone receptor	0.021
Lin7b	lin-7 homolog B (C. elegans)	0.021
Adora2a	adenosine A2a receptor	0.021
Plau	plasminogen activator, urokinase	0.021
Cntn2	contactin 2	0.021
N6amt2	N-6 adenine-specific DNA methyltransferase 2 (putative)	0.021
Gm9880	predicted gene 9880	0.021
BC089491	cDNA sequence BC089491	0.020
Ptgs2	prostaglandin-endoperoxide synthase 2	0.020
Foxh1	forkhead box H1	0.020
Sh3gl2	SH3-domain GRB2-like 2	0.020
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.020
Prlr	prolactin receptor	0.020
Defb11	defensin beta 11	0.020
Psmc3	proteasome (prosome, macropain) 26S subunit, ATPase 3	0.020
Mrps15	mitochondrial ribosomal protein S15	0.019
A930018P22Rik	RIKEN cDNA A930018P22 gene	0.019
Spert	spermatid associated	0.019
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.019
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.019
Clpp	caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)	0.018
Lmx1b	LIM homeobox transcription factor 1 beta	0.018
Vax1	ventral anterior homeobox containing gene 1	0.018
Oprd1	opioid receptor, delta 1	0.018
Esyt3	extended synaptotagmin-like protein 3	0.018
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.018
Mrps25	mitochondrial ribosomal protein S25	0.018
Pitx2	paired-like homeodomain transcription factor 2	0.018
Tdrd1	tudor domain containing 1	0.017
Cops6	COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)	0.017
Tmem151a	transmembrane protein 151A	0.017
Snrpd2	small nuclear ribonucleoprotein D2	0.017
Esr2	estrogen receptor 2 (beta)	0.017
Tpi1	triosephosphate isomerase 1	0.017
Npy2r	neuropeptide Y receptor Y2	0.016
Ret	ret proto-oncogene	0.016
Mrpl23	mitochondrial ribosomal protein L23	0.016
Syngr4	synaptogyrin 4	0.016
Gnao1	guanine nucleotide binding protein, alpha O	0.016
Ptprn	protein tyrosine phosphatase, receptor type, N	0.016
Gabrq	gamma-aminobutyric acid (GABA) A receptor, subunit theta	0.016
Gpr27	G protein-coupled receptor 27	0.016
Lama1	laminin, alpha 1	0.016
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.016
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.016
Alk	anaplastic lymphoma kinase	0.015
Sstr1	somatostatin receptor 1	0.015
Cga	glycoprotein hormones, alpha subunit	0.015
Sncb	synuclein, beta	0.015
Vegfa	vascular endothelial growth factor A	0.015
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.015
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.015
Itga3	integrin alpha 3	0.015
Adra2b	adrenergic receptor, alpha 2b	0.015
Hes2	hairy and enhancer of split 2 (Drosophila)	0.015
1700090G07Rik	RIKEN cDNA 1700090G07 gene	0.015
Bcl2	B-cell leukemia/lymphoma 2	0.015
Slc38a3	solute carrier family 38, member 3	0.015
Mrps17	mitochondrial ribosomal protein S17	0.015
Cpsf3	cleavage and polyadenylation specificity factor 3	0.015
Nat3	N-acetyltransferase 3	0.015
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.014
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.014
Nos3	nitric oxide synthase 3, endothelial cell	0.014
Inhbc	inhibin beta-C	0.014
Slc19a3	solute carrier family 19 (sodium/hydrogen exchanger), member 3	0.014
Phb	prohibitin	0.014
Doc2b	double C2, beta	0.014
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.014
Pacrg	PARK2 co-regulated	0.014
Ugt2b37	UDP glucuronosyltransferase 2 family, polypeptide B37	0.013
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.013
Nt5e	5' nucleotidase, ecto	0.013
Gja5	gap junction protein, alpha 5	0.013
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.013
Snap25	synaptosomal-associated protein 25	0.013
Dmgdh	dimethylglycine dehydrogenase precursor	0.013
Cplx2	complexin 2	0.013
Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor	0.013
Gabrr1	gamma-aminobutyric acid (GABA) C receptor, subunit rho 1	0.013
Fshb	follicle stimulating hormone beta	0.013
Dhh	desert hedgehog	0.013
Agtr2	angiotensin II receptor, type 2	0.013
Ihh	Indian hedgehog	0.013
Sult4a1	sulfotransferase family 4A, member 1	0.013
Arl6ip4	ADP-ribosylation factor-like 6 interacting protein 4	0.012
Aqp2	aquaporin 2	0.012
Syt2	synaptotagmin II	0.012
Mettl7b	methyltransferase like 7B	0.012
Vax2	ventral anterior homeobox containing gene 2	0.012
Brsk2	BR serine/threonine kinase 2	0.012
Syn2	synapsin II	0.012
Sstr4	somatostatin receptor 4	0.012
Lamtor2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	0.012
Psmg1	proteasome (prosome, macropain) assembly chaperone 1	0.012
Cpb2	carboxypeptidase B2 (plasma)	0.012
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.012
Wnt8a	wingless-related MMTV integration site 8A	0.012
Akr1c21	aldo-keto reductase family 1, member C21	0.012
Mrps34	mitochondrial ribosomal protein S34	0.012
Tmem223	transmembrane protein 223	0.012
Pick1	protein interacting with C kinase 1	0.012
Slc12a1	solute carrier family 12, member 1	0.012
Treh	trehalase (brush-border membrane glycoprotein)	0.012
Coq7	demethyl-Q 7	0.012
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.011
Nrip2	nuclear receptor interacting protein 2	0.011
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	0.011
Sypl2	synaptophysin-like 2	0.011
Slc7a13	solute carrier family 7, (cationic amino acid transporter, y+ system) member 13	0.011
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.011
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.011
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.011
Irs2	insulin receptor substrate 2	0.011
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.011
Hrh3	histamine receptor H3	0.011
Wfdc6a	WAP four-disulfide core domain 6A	0.011
Upp2	uridine phosphorylase 2	0.011
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.011
Alas2	aminolevulinic acid synthase 2, erythroid	0.011
Ghrhr	growth hormone releasing hormone receptor	0.011
Klk6	kallikrein related-peptidase 6	0.011
Ccl28	chemokine (C-C motif) ligand 28	0.011
Gal	galanin	0.011
Ctrb1	chymotrypsinogen B1	0.011
Ngb	neuroglobin	0.011
Hint1	histidine triad nucleotide binding protein 1	0.011
Lage3	L antigen family, member 3	0.011
Defb15	defensin beta 15	0.011
Mrps28	mitochondrial ribosomal protein S28	0.011
Amh	anti-Mullerian hormone	0.011
Crlf1	cytokine receptor-like factor 1	0.011
Cabyr	calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)	0.011
Pax8	paired box gene 8	0.011
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.011
Rab3a	RAB3A, member RAS oncogene family	0.011
Npy1r	neuropeptide Y receptor Y1	0.011
Pnma5	paraneoplastic antigen family 5	0.011
9130017N09Rik	RIKEN cDNA 9130017N09 gene	0.011
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.011
Pomc	pro-opiomelanocortin-alpha	0.011
Hba-a2	hemoglobin alpha, adult chain 2	0.011
Ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.011
BC027072	cDNA sequence BC027072	0.011
Smcp	sperm mitochondria-associated cysteine-rich protein	0.011
Tmem147	transmembrane protein 147	0.011
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.011
Spinlw1	serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin)	0.010
C1ql1	complement component 1, q subcomponent-like 1	0.010
Fam83g	family with sequence similarity 83, member G	0.010
Mc1r	melanocortin 1 receptor	0.010
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.010
Urod	uroporphyrinogen decarboxylase	0.010
Lcn3	lipocalin 3	0.010
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.010
Rnf112	ring finger protein 112	0.010
Scn10a	sodium channel, voltage-gated, type X, alpha	0.010
Ufc1	ubiquitin-fold modifier conjugating enzyme 1	0.010
Ahsp	alpha hemoglobin stabilizing protein	0.010
Msgn1	mesogenin 1	0.010
Crygs	crystallin, gamma S	0.010