IMP

Process View

Mus musculus

2 genes annotated in mouse

ral protein signal transduction

A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ral protein signal transduction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ral protein signal transduction" (in gray)

Name	Description	Probability
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.393
Bcl2	B-cell leukemia/lymphoma 2	0.331
Ldb3	LIM domain binding 3	0.322
Vhl	von Hippel-Lindau tumor suppressor	0.276
Akt1	thymoma viral proto-oncogene 1	0.275
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.245
Akt2	thymoma viral proto-oncogene 2	0.217
Prkce	protein kinase C, epsilon	0.191
Rap1gap	Rap1 GTPase-activating protein	0.097
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.092
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.079
Ilk	integrin linked kinase	0.074
Pparg	peroxisome proliferator activated receptor gamma	0.067
Stub1	STIP1 homology and U-Box containing protein 1	0.067
Mapkap1	mitogen-activated protein kinase associated protein 1	0.067
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.060
Actn2	actinin alpha 2	0.060
Vegfa	vascular endothelial growth factor A	0.059
Prkcb	protein kinase C, beta	0.049
Blnk	B-cell linker	0.049
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.048
Cd28	CD28 antigen	0.044
Cd151	CD151 antigen	0.041
Homer1	homer homolog 1 (Drosophila)	0.041
Mapkapk2	MAP kinase-activated protein kinase 2	0.040
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.038
Dlg4	discs, large homolog 4 (Drosophila)	0.037
Igh	immunoglobulin heavy chain complex	0.035
Csnk1g2	casein kinase 1, gamma 2	0.035
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.033
Actn4	actinin alpha 4	0.033
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.033
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.033
Plcb1	phospholipase C, beta 1	0.032
Phf1	PHD finger protein 1	0.032
Npepl1	aminopeptidase-like 1	0.031
Kif3b	kinesin family member 3B	0.030
Bcl3	B-cell leukemia/lymphoma 3	0.030
Git1	G protein-coupled receptor kinase-interactor 1	0.029
Prkca	protein kinase C, alpha	0.028
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.028
Plxnd1	plexin D1	0.027
Sirpa	signal-regulatory protein alpha	0.027
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.027
Trim46	tripartite motif-containing 46	0.026
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.025
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.025
Shank2	SH3/ankyrin domain gene 2	0.025
Man2c1	mannosidase, alpha, class 2C, member 1	0.024
Cd40	CD40 antigen	0.024
Klc1	kinesin light chain 1	0.023
Pdgfb	platelet derived growth factor, B polypeptide	0.023
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.022
Plcg1	phospholipase C, gamma 1	0.022
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.022
Ate1	arginyltransferase 1	0.021
Ctdnep1	CTD nuclear envelope phosphatase 1	0.021
Gramd1a	GRAM domain containing 1A	0.021
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.021
Src	Rous sarcoma oncogene	0.021
Igf1r	insulin-like growth factor I receptor	0.021
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.020
Faah	fatty acid amide hydrolase	0.020
Arhgap1	Rho GTPase activating protein 1	0.020
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.019
Plxna1	plexin A1	0.019
Flii	flightless I homolog (Drosophila)	0.019
Lrp10	low-density lipoprotein receptor-related protein 10	0.019
Fas	Fas (TNF receptor superfamily member 6)	0.019
Lepr	leptin receptor	0.019
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.018
Sh2b3	SH2B adaptor protein 3	0.018
Sec14l1	SEC14-like 1 (S. cerevisiae)	0.018
Rasal1	RAS protein activator like 1 (GAP1 like)	0.018
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.018
Atp13a2	ATPase type 13A2	0.017
Dctn1	dynactin 1	0.017
Add1	adducin 1 (alpha)	0.017
Gtpbp2	GTP binding protein 2	0.017
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.017
Tmem189	transmembrane protein 189	0.016
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.016
Cdc42se1	CDC42 small effector 1	0.016
Adrbk1	adrenergic receptor kinase, beta 1	0.016
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.016
Gna12	guanine nucleotide binding protein, alpha 12	0.016
Mgat4b	mannoside acetylglucosaminyltransferase 4, isoenzyme B	0.016
Vasp	vasodilator-stimulated phosphoprotein	0.016
Pea15a	phosphoprotein enriched in astrocytes 15A	0.016
Mgrn1	mahogunin, ring finger 1	0.016
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.016
Pacs2	phosphofurin acidic cluster sorting protein 2	0.016
Dnm1	dynamin 1	0.016
Ahi1	Abelson helper integration site 1	0.016
Lemd2	LEM domain containing 2	0.015
Srgap2	SLIT-ROBO Rho GTPase activating protein 2	0.015
Braf	Braf transforming gene	0.015
Parp6	poly (ADP-ribose) polymerase family, member 6	0.015
Pip5k1b	phosphatidylinositol-4-phosphate 5-kinase, type 1 beta	0.015
Arf3	ADP-ribosylation factor 3	0.015
Pfkl	phosphofructokinase, liver, B-type	0.014
Ncoa3	nuclear receptor coactivator 3	0.014
Grb7	growth factor receptor bound protein 7	0.014
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.014
Frmd8	FERM domain containing 8	0.014
Gsk3b	glycogen synthase kinase 3 beta	0.014
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.014
Ltbr	lymphotoxin B receptor	0.014
Limk2	LIM motif-containing protein kinase 2	0.013
Dlg2	discs, large homolog 2 (Drosophila)	0.013
Sorl1	sortilin-related receptor, LDLR class A repeats-containing	0.013
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.013
Abca2	ATP-binding cassette, sub-family A (ABC1), member 2	0.013
Mbp	myelin basic protein	0.013
Baiap2l1	BAI1-associated protein 2-like 1	0.013
Adcy6	adenylate cyclase 6	0.013
Myo1c	myosin IC	0.013
Trim35	tripartite motif-containing 35	0.013
Kctd20	potassium channel tetramerisation domain containing 20	0.013
Eif2c3	eukaryotic translation initiation factor 2C, 3	0.013
Coro1c	coronin, actin binding protein 1C	0.013
Dsg1a	desmoglein 1 alpha	0.013
Wdr1	WD repeat domain 1	0.013
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.013
Rasgrp1	RAS guanyl releasing protein 1	0.013
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.013
Dgka	diacylglycerol kinase, alpha	0.013
Mapk3	mitogen-activated protein kinase 3	0.012
Plp1	proteolipid protein (myelin) 1	0.012
Tubb4	tubulin, beta 4	0.012
Slc12a5	solute carrier family 12, member 5	0.012
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.012
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.012
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.012
Slc4a2	solute carrier family 4 (anion exchanger), member 2	0.012
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.012
Usp12	ubiquitin specific peptidase 12	0.012
Fbrs	fibrosin	0.012
Lmna	lamin A	0.012
Vps37b	vacuolar protein sorting 37B (yeast)	0.012
Pygo2	pygopus 2	0.012
Osbpl6	oxysterol binding protein-like 6	0.012
Itpk1	inositol 1,3,4-triphosphate 5/6 kinase	0.012
Nell2	NEL-like 2 (chicken)	0.012
Mapk7	mitogen-activated protein kinase 7	0.012
Ptgds	prostaglandin D2 synthase (brain)	0.011
Pnpla2	patatin-like phospholipase domain containing 2	0.011
Ugt8a	UDP galactosyltransferase 8A	0.011
Efhd1	EF hand domain containing 1	0.011
Bag6	BCL2-associated athanogene 6	0.011
Vps18	vacuolar protein sorting 18 (yeast)	0.011
Ssbp4	single stranded DNA binding protein 4	0.011
Rhog	ras homolog gene family, member G	0.011
Ids	iduronate 2-sulfatase	0.011
Cln3	ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	0.011
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.011
Syn2	synapsin II	0.011
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.011
Raf1	v-raf-leukemia viral oncogene 1	0.011
Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.011
Tbc1d20	TBC1 domain family, member 20	0.011
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	0.011
Hspa4l	heat shock protein 4 like	0.011
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.011
Arc	activity regulated cytoskeletal-associated protein	0.011
Npy1r	neuropeptide Y receptor Y1	0.011
Prss8	protease, serine, 8 (prostasin)	0.011
Dact3	dapper homolog 3, antagonist of beta-catenin (xenopus)	0.011
Mtap7	microtubule-associated protein 7	0.010
Cish	cytokine inducible SH2-containing protein	0.010
Fam171a1	family with sequence similarity 171, member A1	0.010
Mark2	MAP/microtubule affinity-regulating kinase 2	0.010
C230081A13Rik	RIKEN cDNA C230081A13 gene	0.010
Myh14	myosin, heavy polypeptide 14	0.010
Mark4	MAP/microtubule affinity-regulating kinase 4	0.010
Itga3	integrin alpha 3	0.010
Dusp4	dual specificity phosphatase 4	0.010
Pex5	peroxisomal biogenesis factor 5	0.010
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.010
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.010
Plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.010
Samd4b	sterile alpha motif domain containing 4B	0.010
Abca7	ATP-binding cassette, sub-family A (ABC1), member 7	0.010
Rgs11	regulator of G-protein signaling 11	0.010
Capn1	calpain 1	0.010
Tesk1	testis specific protein kinase 1	0.010
Fgf1	fibroblast growth factor 1	0.010
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.010
Sept9	septin 9	0.010
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.010
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.010
Pla2g6	phospholipase A2, group VI	0.010
Clmn	calmin	0.010
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.010