IMP

Process View

Mus musculus

4 genes annotated in mouse

response to muscle inactivity involved in regulation of muscle adaptation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to muscle inactivity involved in regulation of muscle adaptation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to muscle inactivity involved in regulation of muscle adaptation" (in gray)

Name	Description	Probability	Func Analog Organism
Eif3f	eukaryotic translation initiation factor 3, subunit F	0.897
Mef2d	myocyte enhancer factor 2D	0.827
Trim63	tripartite motif-containing 63	0.774
Pax7	paired box gene 7	0.659
Trim55	tripartite motif-containing 55	0.625	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.611
Myog	myogenin	0.507
Tbx5	T-box 5	0.484
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.437
Myf5	myogenic factor 5	0.273	Mouse
Myf6	myogenic factor 6	0.270	Mouse
Mstn	myostatin	0.268
Ryr2	ryanodine receptor 2, cardiac	0.246
Xirp1	xin actin-binding repeat containing 1	0.240
Smad3	MAD homolog 3 (Drosophila)	0.218
Mef2c	myocyte enhancer factor 2C	0.196
Grb10	growth factor receptor bound protein 10	0.171
Gjd3	gap junction protein, delta 3	0.136
Mybph	myosin binding protein H	0.122
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.112
Tnnc2	troponin C2, fast	0.109
Rnf11	ring finger protein 11	0.100
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.094
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.089
Tnni2	troponin I, skeletal, fast 2	0.081
Ckmt2	creatine kinase, mitochondrial 2	0.069
Myh8	myosin, heavy polypeptide 8, skeletal muscle, perinatal	0.068
Fbxo32	F-box protein 32	0.068
Tbx3	T-box 3	0.068
Hrc	histidine rich calcium binding protein	0.064
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.060
Myot	myotilin	0.055
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.052
Gtf2i	general transcription factor II I	0.045
Cav3	caveolin 3	0.045
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.042
Hdac5	histone deacetylase 5	0.041	Mouse
Mybpc1	myosin binding protein C, slow-type	0.040
Tbx1	T-box 1	0.037
Hoxa4	homeobox A4	0.037
Gja5	gap junction protein, alpha 5	0.036
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.036
Lmod2	leiomodin 2 (cardiac)	0.036
Myoz2	myozenin 2	0.035
Wbp1	WW domain binding protein 1	0.033
Add1	adducin 1 (alpha)	0.031
Tpm1	tropomyosin 1, alpha	0.031
Smtnl1	smoothelin-like 1	0.030
Sqstm1	sequestosome 1	0.029
Rapsn	receptor-associated protein of the synapse	0.029
Myod1	myogenic differentiation 1	0.028	Mouse
Myom2	myomesin 2	0.028
Asb12	ankyrin repeat and SOCS box-containing 12	0.028
Ldb1	LIM domain binding 1	0.027
Asb10	ankyrin repeat and SOCS box-containing 10	0.027
Ldb3	LIM domain binding 3	0.027
Myom3	myomesin family, member 3	0.027
Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.026
Mll2	myeloid/lymphoid or mixed-lineage leukemia 2	0.026
Mef2a	myocyte enhancer factor 2A	0.023
Lmod3	leiomodin 3 (fetal)	0.023
Myoz1	myozenin 1	0.023
H2afz	H2A histone family, member Z	0.023
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.023
Kbtbd5	kelch repeat and BTB (POZ) domain containing 5	0.022
Csrp3	cysteine and glycine-rich protein 3	0.022
Itgax	integrin alpha X	0.022
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.022
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.022
Art1	ADP-ribosyltransferase 1	0.022
Spnb2	spectrin beta 2	0.022
Klhl24	kelch-like 24 (Drosophila)	0.021
Tnnt3	troponin T3, skeletal, fast	0.021
Pax3	paired box gene 3	0.021
Was	Wiskott-Aldrich syndrome homolog (human)	0.020
Tmem182	transmembrane protein 182	0.020
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.019
Thra	thyroid hormone receptor alpha	0.019
Ypel3	yippee-like 3 (Drosophila)	0.019
Krtap6-1	keratin associated protein 6-1	0.019
Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide	0.018
Hoxb4	homeobox B4	0.018
Gata3	GATA binding protein 3	0.018
Myl1	myosin, light polypeptide 1	0.018
Met	met proto-oncogene	0.018
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.018
Invs	inversin	0.018
Tef	thyrotroph embryonic factor	0.017
Mtap4	microtubule-associated protein 4	0.017
Myh3	myosin, heavy polypeptide 3, skeletal muscle, embryonic	0.017
Phf1	PHD finger protein 1	0.017
Ikzf1	IKAROS family zinc finger 1	0.017
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.017
Tbx4	T-box 4	0.017
2310002L09Rik	RIKEN cDNA 2310002L09 gene	0.016
Prkcq	protein kinase C, theta	0.016
Oaz2-ps	ornithine decarboxylase antizyme 2, pseudogene	0.016
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.016
Rpa3	replication protein A3	0.016
Ptrf	polymerase I and transcript release factor	0.015
Sprr2i	small proline-rich protein 2I	0.015
Neurod4	neurogenic differentiation 4	0.015
Shox2	short stature homeobox 2	0.015
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.015
Smyd1	SET and MYND domain containing 1	0.015
Kera	keratocan	0.014
Kif1b	kinesin family member 1B	0.014
Tbx15	T-box 15	0.014
Rpl3l	ribosomal protein L3-like	0.014
Gtpbp2	GTP binding protein 2	0.014
Fktn	fukutin	0.014
Tmod4	tropomodulin 4	0.013
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.013
Il27ra	interleukin 27 receptor, alpha	0.013
Inpp5k	inositol polyphosphate 5-phosphatase K	0.013
Prrg2	proline-rich Gla (G-carboxyglutamic acid) polypeptide 2	0.013
Chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.013
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.012
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.012
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.012
Creb1	cAMP responsive element binding protein 1	0.012
Hspb3	heat shock protein 3	0.012
Ccl5	chemokine (C-C motif) ligand 5	0.012
Prkch	protein kinase C, eta	0.012
Dag1	dystroglycan 1	0.011
Rnf167	ring finger protein 167	0.011
Trdn	triadin	0.011
Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.011
Smad5	MAD homolog 5 (Drosophila)	0.011
Mms19	MMS19 (MET18 S. cerevisiae)	0.011
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.011
Myl3	myosin, light polypeptide 3	0.011
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.011
Tbc1d10c	TBC1 domain family, member 10c	0.011
Alpk3	alpha-kinase 3	0.011
Synpo2l	synaptopodin 2-like	0.010
Asb11	ankyrin repeat and SOCS box-containing 11	0.010
Pmepa1	prostate transmembrane protein, androgen induced 1	0.010
Usp1	ubiquitin specific peptidase 1	0.010
Anln	anillin, actin binding protein	0.010
Kbtbd10	kelch repeat and BTB (POZ) domain containing 10	0.010
Tnni1	troponin I, skeletal, slow 1	0.010
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.010