IMP

Process View

Mus musculus

10 genes annotated in mouse

negative regulation of fatty acid metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of fatty acid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of fatty acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Pparg	peroxisome proliferator activated receptor gamma	0.758
Atf4	activating transcription factor 4	0.741
Pnpla2	patatin-like phospholipase domain containing 2	0.631
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.585
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.566
Brca2	breast cancer 2	0.439
Esr1	estrogen receptor 1 (alpha)	0.417
Lepr	leptin receptor	0.386
Mdm2	transformed mouse 3T3 cell double minute 2	0.313
Irs2	insulin receptor substrate 2	0.201
Kiss1	KiSS-1 metastasis-suppressor	0.169
Trp53	transformation related protein 53	0.119
Mapkap1	mitogen-activated protein kinase associated protein 1	0.118
Akt2	thymoma viral proto-oncogene 2	0.097
Rb1	retinoblastoma 1	0.095
Atr	ataxia telangiectasia and Rad3 related	0.093
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.081
Phyh	phytanoyl-CoA hydroxylase	0.075
Abhd5	abhydrolase domain containing 5	0.068
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.060
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.053
Ncoa3	nuclear receptor coactivator 3	0.051
Ghr	growth hormone receptor	0.041
Slc25a20	solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20	0.040
Clock	circadian locomotor output cycles kaput	0.037
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.036
Rsbn1	rosbin, round spermatid basic protein 1	0.036
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.035
Stk11	serine/threonine kinase 11	0.034
Etfa	electron transferring flavoprotein, alpha polypeptide	0.033
Hsdl2	hydroxysteroid dehydrogenase like 2	0.031
Acad11	acyl-Coenzyme A dehydrogenase family, member 11	0.031
Clpx	caseinolytic peptidase X (E.coli)	0.031
Chmp1b	chromatin modifying protein 1B	0.027
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.026
Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	0.025
Prlr	prolactin receptor	0.024
Mlycd	malonyl-CoA decarboxylase	0.023
Siah1b	seven in absentia 1B	0.023
Plin4	perilipin 4	0.021
Wasf2	WAS protein family, member 2	0.020
Cidec	cell death-inducing DFFA-like effector c	0.020
Hadha	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	0.020
Ccnd1	cyclin D1	0.019
Arpc4	actin related protein 2/3 complex, subunit 4	0.019
Decr1	2,4-dienoyl CoA reductase 1, mitochondrial	0.019
Samd4b	sterile alpha motif domain containing 4B	0.018
Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1	0.018
Per2	period homolog 2 (Drosophila)	0.018
E2f1	E2F transcription factor 1	0.017
Ar	androgen receptor	0.017
Acads	acyl-Coenzyme A dehydrogenase, short chain	0.017
Kcmf1	potassium channel modulatory factor 1	0.016
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.016
Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.015
Cpt2	carnitine palmitoyltransferase 2	0.015
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.015
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.015
Retsat	retinol saturase (all trans retinol 13,14 reductase)	0.015
Ephx2	epoxide hydrolase 2, cytoplasmic	0.015
Ech1	enoyl coenzyme A hydratase 1, peroxisomal	0.014
Aifm2	apoptosis-inducing factor, mitochondrion-associated 2	0.014
Rad51	RAD51 homolog (S. cerevisiae)	0.014
Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2	0.014
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.014
Etfdh	electron transferring flavoprotein, dehydrogenase	0.014
Lipe	lipase, hormone sensitive	0.013
Sp1	trans-acting transcription factor 1	0.013
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.013
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.013
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.013
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.013
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.012
Pex11a	peroxisomal biogenesis factor 11 alpha	0.012
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.012
Pim3	proviral integration site 3	0.012
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.012
Phkb	phosphorylase kinase beta	0.012
Msh2	mutS homolog 2 (E. coli)	0.012
Cbr4	carbonyl reductase 4	0.012
Capzb	capping protein (actin filament) muscle Z-line, beta	0.011
Eci2	enoyl-Coenzyme A delta isomerase 2	0.011
Chpt1	choline phosphotransferase 1	0.011
Acaca	acetyl-Coenzyme A carboxylase alpha	0.011	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.011
Acat1	acetyl-Coenzyme A acetyltransferase 1	0.011
Rfwd2	ring finger and WD repeat domain 2	0.010
Jarid2	jumonji, AT rich interactive domain 2	0.010
Wwox	WW domain-containing oxidoreductase	0.010
Chac1	ChaC, cation transport regulator-like 1 (E. coli)	0.010
Elmod3	ELMO/CED-12 domain containing 3	0.010
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.010
Adipor2	adiponectin receptor 2	0.010