IMP

Process View

Mus musculus

10 genes annotated in mouse

lung associated mesenchyme development

The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lung associated mesenchyme development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lung associated mesenchyme development" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.997
Fgfr2	fibroblast growth factor receptor 2	0.983
Gli3	GLI-Kruppel family member GLI3	0.982
Pax2	paired box gene 2	0.870
Pax8	paired box gene 8	0.816
Hoxb5	homeobox B5	0.638	Mouse
Hoxa11	homeobox A11	0.633
Fgf8	fibroblast growth factor 8	0.609
Hoxb6	homeobox B6	0.597	Mouse
Hoxd11	homeobox D11	0.569
Bmp4	bone morphogenetic protein 4	0.549
Hoxd9	homeobox D9	0.541
Lhx1	LIM homeobox protein 1	0.540
Gli2	GLI-Kruppel family member GLI2	0.535
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.492
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.475
Tcf21	transcription factor 21	0.421
Hoxa2	homeobox A2	0.389
Hoxa10	homeobox A10	0.380
Fgf10	fibroblast growth factor 10	0.379	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.357	Mouse
Hoxa5	homeobox A5	0.342
Hoxd8	homeobox D8	0.315	Mouse
Hoxc5	homeobox C5	0.312	Mouse
Hoxa9	homeobox A9	0.291
Tbx2	T-box 2	0.273
Hoxb3	homeobox B3	0.256
Fgfr1	fibroblast growth factor receptor 1	0.252
Twist2	twist homolog 2 (Drosophila)	0.242
Gli1	GLI-Kruppel family member GLI1	0.241
Rarg	retinoic acid receptor, gamma	0.212
Hoxc6	homeobox C6	0.208	Mouse
Hoxa4	homeobox A4	0.201	Mouse
Pbx1	pre B-cell leukemia transcription factor 1	0.201
Tbx3	T-box 3	0.200
T	brachyury	0.189
Hoxd3	homeobox D3	0.188
Hoxa3	homeobox A3	0.176
Sox9	SRY-box containing gene 9	0.173
Fgf18	fibroblast growth factor 18	0.170
Hoxb9	homeobox B9	0.169
Nog	noggin	0.167
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.161
Hoxd10	homeobox D10	0.148
Fgf9	fibroblast growth factor 9	0.144
Trp63	transformation related protein 63	0.143
Lmx1a	LIM homeobox transcription factor 1 alpha	0.143
Fgfr3	fibroblast growth factor receptor 3	0.134	Mouse
Emid2	EMI domain containing 2	0.134
Alx4	aristaless-like homeobox 4	0.131
Wt1	Wilms tumor 1 homolog	0.121
Hoxc4	homeobox C4	0.121	Mouse
Hoxd4	homeobox D4	0.117	Mouse
Hoxc8	homeobox C8	0.113	Mouse
Msx2	homeobox, msh-like 2	0.109
Hoxc9	homeobox C9	0.099
Foxa2	forkhead box A2	0.094
Chrd	chordin	0.093
Nodal	nodal	0.086
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.083
Rarb	retinoic acid receptor, beta	0.081
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.080
Gdnf	glial cell line derived neurotrophic factor	0.079
Hoxb2	homeobox B2	0.078
Bnc1	basonuclin 1	0.075
Sox7	SRY-box containing gene 7	0.075
Tbx15	T-box 15	0.073
Pthlh	parathyroid hormone-like peptide	0.071
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.068
Lama5	laminin, alpha 5	0.064
Wnt6	wingless-related MMTV integration site 6	0.064	Mouse
Hoxb4	homeobox B4	0.063	Mouse
Pax3	paired box gene 3	0.063
Pou3f3	POU domain, class 3, transcription factor 3	0.061
Foxb1	forkhead box B1	0.060
En1	engrailed 1	0.056
Tcf15	transcription factor 15	0.056
Efna4	ephrin A4	0.056
Emx2	empty spiracles homolog 2 (Drosophila)	0.056
Fzd8	frizzled homolog 8 (Drosophila)	0.055
Nkx2-1	NK2 homeobox 1	0.055
Ihh	Indian hedgehog	0.052	Mouse
Dhh	desert hedgehog	0.052	Mouse
Hoxd1	homeobox D1	0.050
Meox2	mesenchyme homeobox 2	0.050
Ctnnb1	catenin (cadherin associated protein), beta 1	0.045
Fzd10	frizzled homolog 10 (Drosophila)	0.043
Vangl2	vang-like 2 (van gogh, Drosophila)	0.043
Lrp2	low density lipoprotein receptor-related protein 2	0.042
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.042
Angpt4	angiopoietin 4	0.041
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.041
Wnt1	wingless-related MMTV integration site 1	0.039	Mouse
Wnt10b	wingless related MMTV integration site 10b	0.039	Mouse
Hoxa7	homeobox A7	0.039	Mouse
Dmrt1	doublesex and mab-3 related transcription factor 1	0.038
Ptch2	patched homolog 2	0.037
Sim2	single-minded homolog 2 (Drosophila)	0.036
Gata6	GATA binding protein 6	0.036
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.036
Sall4	sal-like 4 (Drosophila)	0.035
Tbx1	T-box 1	0.035
Rara	retinoic acid receptor, alpha	0.034
Hoxa1	homeobox A1	0.034
Otx1	orthodenticle homolog 1 (Drosophila)	0.033
Lhx3	LIM homeobox protein 3	0.033
Foxc1	forkhead box C1	0.032
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.032
Rxra	retinoid X receptor alpha	0.032
Kcnk3	potassium channel, subfamily K, member 3	0.032
Foxd2	forkhead box D2	0.032
Edn3	endothelin 3	0.031
Npr3	natriuretic peptide receptor 3	0.031
Psg17	pregnancy specific glycoprotein 17	0.031
Fgf3	fibroblast growth factor 3	0.031	Mouse
Btbd17	BTB (POZ) domain containing 17	0.031
Wnt4	wingless-related MMTV integration site 4	0.030	Mouse
Upk3b	uroplakin 3B	0.029
Smad6	MAD homolog 6 (Drosophila)	0.029
Pax1	paired box gene 1	0.028
Axin2	axin2	0.028
Pitx2	paired-like homeodomain transcription factor 2	0.028
Acan	aggrecan	0.028
Cdx1	caudal type homeobox 1	0.028
Ar	androgen receptor	0.027
Foxf1a	forkhead box F1a	0.027
Efna2	ephrin A2	0.027
Sult5a1	sulfotransferase family 5A, member 1	0.026
Hmx3	H6 homeobox 3	0.026
Col13a1	collagen, type XIII, alpha 1	0.026
Hrc	histidine rich calcium binding protein	0.026
Ptgfr	prostaglandin F receptor	0.026
Fgf15	fibroblast growth factor 15	0.025
Fgfbp1	fibroblast growth factor binding protein 1	0.025
Hoxa13	homeobox A13	0.025
Fgfr4	fibroblast growth factor receptor 4	0.025	Mouse
Efnb1	ephrin B1	0.025
Otx2	orthodenticle homolog 2 (Drosophila)	0.024
Amhr2	anti-Mullerian hormone type 2 receptor	0.024
Ret	ret proto-oncogene	0.024
Lrp6	low density lipoprotein receptor-related protein 6	0.024
Gja5	gap junction protein, alpha 5	0.024
Adra2c	adrenergic receptor, alpha 2c	0.024
Tcfap2c	transcription factor AP-2, gamma	0.023
Stc2	stanniocalcin 2	0.023
Prrx1	paired related homeobox 1	0.023
Smyd1	SET and MYND domain containing 1	0.022
Wnt5a	wingless-related MMTV integration site 5A	0.022	Mouse
Pcdh12	protocadherin 12	0.022
Hoxb8	homeobox B8	0.022	Mouse
Hoxb13	homeobox B13	0.022
Cdh3	cadherin 3	0.022
Bmp7	bone morphogenetic protein 7	0.022
Padi3	peptidyl arginine deiminase, type III	0.021
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.021
Barx1	BarH-like homeobox 1	0.021
Dlx5	distal-less homeobox 5	0.021
Foxf2	forkhead box F2	0.021
Clcnka	chloride channel Ka	0.021
Adra2b	adrenergic receptor, alpha 2b	0.021
Hoxb1	homeobox B1	0.021
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.021
Hes1	hairy and enhancer of split 1 (Drosophila)	0.021
Wnt11	wingless-related MMTV integration site 11	0.020	Mouse
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.020
Gpc3	glypican 3	0.020
Uncx	UNC homeobox	0.020
Rem1	rad and gem related GTP binding protein 1	0.020
Ebf3	early B-cell factor 3	0.019
Foxc2	forkhead box C2	0.019
Tcl1	T-cell lymphoma breakpoint 1	0.019
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.019
Gjb5	gap junction protein, beta 5	0.019
Fzd1	frizzled homolog 1 (Drosophila)	0.019
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.019
Zfp185	zinc finger protein 185	0.019
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.018
Des	desmin	0.018
Col22a1	collagen, type XXII, alpha 1	0.018
Vax1	ventral anterior homeobox containing gene 1	0.018
Cdh6	cadherin 6	0.018
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.018
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.017
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.017
Prx	periaxin	0.017
Kl	klotho	0.017
Ptk7	PTK7 protein tyrosine kinase 7	0.017
Gata5	GATA binding protein 5	0.017
Esrrb	estrogen related receptor, beta	0.017
Foxb2	forkhead box B2	0.017
Clic3	chloride intracellular channel 3	0.016
Msx1	homeobox, msh-like 1	0.016
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.016
Fgf4	fibroblast growth factor 4	0.016	Mouse
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.016
Hoxd13	homeobox D13	0.016
Hoxb7	homeobox B7	0.016	Mouse
Arx	aristaless related homeobox	0.016
Wnt2b	wingless related MMTV integration site 2b	0.016	Mouse
C77370	expressed sequence C77370	0.016
Pou3f1	POU domain, class 3, transcription factor 1	0.016
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.016
Wnt3	wingless-related MMTV integration site 3	0.015	Mouse
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.015
Alx3	aristaless-like homeobox 3	0.015
Myod1	myogenic differentiation 1	0.015
Tcfap2a	transcription factor AP-2, alpha	0.015
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.014
Gm13290	predicted gene 13290	0.014
Foxa1	forkhead box A1	0.014
Foxd3	forkhead box D3	0.014
Gbx2	gastrulation brain homeobox 2	0.014
Epha1	Eph receptor A1	0.014
Pou5f1	POU domain, class 5, transcription factor 1	0.014
Gdf11	growth differentiation factor 11	0.014
Pitx1	paired-like homeodomain transcription factor 1	0.013
Grem1	gremlin 1	0.013
Meis1	Meis homeobox 1	0.013
Rhcg	Rhesus blood group-associated C glycoprotein	0.013
Ntf3	neurotrophin 3	0.013
Prrx2	paired related homeobox 2	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Tacr2	tachykinin receptor 2	0.013
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.013
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.012
Wnt5b	wingless-related MMTV integration site 5B	0.012	Mouse
Nobox	NOBOX oogenesis homeobox	0.012
Barx2	BarH-like homeobox 2	0.012
Zfp503	zinc finger protein 503	0.012
Gjb4	gap junction protein, beta 4	0.012
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.012
Foxh1	forkhead box H1	0.012
Nes	nestin	0.012
Kcna7	potassium voltage-gated channel, shaker-related subfamily, member 7	0.012
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.012
Oprd1	opioid receptor, delta 1	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.011
Foxd1	forkhead box D1	0.011
Tlx2	T-cell leukemia, homeobox 2	0.011
Pkdcc	protein kinase domain containing, cytoplasmic	0.011
Mgat3	mannoside acetylglucosaminyltransferase 3	0.011
Sim1	single-minded homolog 1 (Drosophila)	0.011
Calcoco2	calcium binding and coiled-coil domain 2	0.011
Nkx3-2	NK3 homeobox 2	0.011
Adra1a	adrenergic receptor, alpha 1a	0.011
Bcam	basal cell adhesion molecule	0.011
Scx	scleraxis	0.011
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.011
Fgf22	fibroblast growth factor 22	0.010	Mouse
Tead3	TEA domain family member 3	0.010
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.010
Gpr50	G-protein-coupled receptor 50	0.010
Ctf1	cardiotrophin 1	0.010
Guca2b	guanylate cyclase activator 2b (retina)	0.010