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Process View

Danio rerio

7 genes annotated in zebrafish

lens morphogenesis in camera type eye

GO:0002089

The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lens morphogenesis in camera type eye"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lens morphogenesis in camera type eye" (in gray)

Name	Description	Probability	Func Analog Organism
crygmxl2	crystallin, gamma MX, like 2	0.891
sox2	SRY-box containing gene 2	0.850	Mouse
dlc	deltaC	0.833
zgc:153846	zgc:153846	0.717	Mouse
foxa2	forkhead box A2	0.619	Zebrafish
pax6a	paired box gene 6a	0.551	Zebrafish
crygm6	crystallin, gamma M6	0.533	Mouse
crygm3	crystallin, gamma M3	0.504
pea3	ETS-domain transcription factor pea3	0.372
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.372
mab21l2	mab-21-like 2	0.342
crygm1	crystallin, gamma M1	0.337	Mouse
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.321
otx2	orthodenticle homolog 2	0.297
sox10	SRY-box containing gene 10	0.263
pax6b	paired box gene 6b	0.262
otx1b	orthodenticle homolog 1b	0.207
crygmxl1	crystallin, gamma MX, like 1	0.204	Mouse
foxa3	forkhead box A3	0.190	Zebrafish
cryba4	crystallin, beta A4	0.186
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.184
crygm2f	crystallin, gamma M2f	0.183
cdh2	cadherin 2, neuronal	0.177
crygmx	crystallin, gamma MX	0.168
zgc:103750	zgc:103750	0.168
crybb1	crystallin, beta B1	0.165
crygm2a	crystallin, gamma M2a	0.153	Mouse
bmper	BMP binding endothelial regulator	0.152
crygm2d16	crystallin, gamma M2d16	0.143
crygn2	crystallin, gamma N2	0.139
foxi3b	forkhead box I3b	0.137	Zebrafish
crygn1	crystallin, gamma N1	0.117
crygm2d11	crystallin, gamma M2d11	0.111	Mouse
zgc:171792	zgc:171792	0.111
tp63	tumor protein p63	0.104
crygs4	crystallin, gamma S4	0.103
crygm2d8	crystallin, gamma M2d8	0.101	Mouse
zdhhc8b	zinc finger, DHHC-type containing 8b	0.100
foxi1	forkhead box I1	0.094	Zebrafish
crygm2d15	crystallin, gamma M2d15	0.093	Mouse
crygm2b	crystallin, gamma M2b	0.091
pxn	paxillin	0.090
six3b	sine oculis homeobox homolog 3b	0.082	Mouse
rx3	retinal homeobox gene 3	0.078
rx2	retinal homeobox gene 2	0.076
crygm7	crystallin, gamma M7	0.073	Mouse
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.071
crygm2d13	crystallin, gamma M2d13	0.068	Mouse
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.068
nrarpa	notch-regulated ankyrin repeat protein a	0.068
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.066
crygm2d6	crystallin, gamma M2d6	0.064
her1	hairy-related 1	0.063
rarga	retinoic acid receptor gamma a	0.062
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.059
pitx2	paired-like homeodomain transcription factor 2	0.059
six2a	sine oculis-related homeobox 2a	0.057
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.055
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.055
pax2a	paired box gene 2a	0.054
myod1	myogenic differentiation 1	0.050
crygs1	crystallin, gamma S1	0.050
rbp4	retinol binding protein 4, plasma	0.049
tfe3b	transcription factor binding to IGHM enhancer 3b	0.048
rx1	retinal homeobox gene 1	0.047
efnb2a	ephrin B2a	0.046
crygm2d12	crystallin, gamma M2d12	0.045	Mouse
her6	hairy-related 6	0.044
bmp2b	bone morphogenetic protein 2b	0.044
vcana	versican a	0.043
vsx2	visual system homeobox 2	0.043
fgfrl1b	fibroblast growth factor receptor-like 1b	0.041
hmx4	H6 family homeobox 4	0.038
coe2	coe2	0.036
vwf	von Willebrand factor	0.034
cryba2a	crystallin, beta A2a	0.034
gbx2	gastrulation brain homeo box 2	0.034
boc	brother of CDO	0.034
crygm4	crystallin, gamma M4	0.033	Mouse
emx2	empty spiracles homeobox 2	0.033
pdgfaa	platelet-derived growth factor alpha a	0.032
crygm5	crystallin, gamma M5	0.031	Mouse
crygm2d2	crystallin, gamma M2d2	0.031
sfrp1b	secreted frizzled-related protein 1b	0.031
foxe3	forkhead box E3	0.030
six3a	sine oculis homeobox homolog 3a	0.029
foxa1	forkhead box A1	0.029	Zebrafish
foxg1a	forkhead box G1a	0.029	Zebrafish
fgf3	fibroblast growth factor 3	0.029
tnc	tenascin C	0.029	Zebrafish
rad21	RAD21 homolog (S. pombe)	0.028
foxi3a	forkhead box I3a	0.028	Zebrafish
bhlhe22	basic helix-loop-helix family, member e22	0.028
emx3	empty spiracles homeobox 3	0.028
pknox2	pbx/knotted 1 homeobox 2	0.027
crygm2d10	crystallin, gamma M2d10	0.027
fgfr2	fibroblast growth factor receptor 2	0.027
sox1a	SRY-box containing gene 1a	0.026
dmrt2a	doublesex and mab-3 related transcription factor 2a	0.025
crygm2c	crystallin, gamma M2c	0.025	Mouse
zgc:112285	zgc:112285	0.025
nkx2.1b	NK2 homeobox 1b	0.025
znf503	zinc finger protein 503	0.024
dlx4a	distal-less homeobox gene 4a	0.024
irx4b	iroquois homeobox protein 4b	0.023
LOC799807	novel protein similar to crystallin, gamma family	0.022
twist1a	twist1a	0.022
eya1	eyes absent homolog 1	0.021
dlx5a	distal-less homeobox gene 5a	0.021
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.021
spry4	sprouty (Drosophila) homolog 4	0.021
zgc:194131	zgc:194131	0.021
zgc:114181	zgc:114181	0.020
dlx1a	distal-less homeobox gene 1a	0.020
shha	sonic hedgehog a	0.020
edn1	endothelin 1	0.019
dnmt6	DNA (cytosine-5-)-methyltransferase 6	0.019
atoh7	atonal homolog 7	0.019
zgc:101859	zgc:101859	0.018
sc:d411	sc:d411	0.018
wif1	wnt inhibitory factor 1	0.018
tgfb1a	transforming growth factor, beta 1a	0.018
crygm2d7	crystallin, gamma M2d7	0.018
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.018
raraa	retinoic acid receptor, alpha a	0.017
notch1a	notch homolog 1a	0.017
jag1b	jagged 1b	0.017
lama5	laminin, alpha 5	0.017
notch3	notch homolog 3	0.017
aldob	aldolase b, fructose-bisphosphate	0.017
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.017
dlx3b	distal-less homeobox gene 3b	0.016
dct	dopachrome tautomerase	0.016
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.016
lctla	lactase-like a	0.016
smoc1	SPARC related modular calcium binding 1	0.015
msxc	muscle segment homeobox C	0.015
ptpra	protein tyrosine phosphatase, receptor type, A	0.015
ptf1a	pancreas specific transcription factor, 1a	0.015
optc	opticin	0.015
lhx1b	LIM homeobox 1b	0.014
gata3	GATA-binding protein 3	0.014
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.014
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.014
dlx4b	distal-less homeobox gene 4b	0.013
id3	inhibitor of DNA binding 3	0.013
barhl2	BarH-like 2	0.013
tfa	transferrin-a	0.013
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.013
im:7164961	im:7164961	0.013
lef1	lymphocyte enhancer binding factor 1	0.013
hoxc9a	homeo box C9a	0.013
dacha	dachshund a	0.013
fbn2b	fibrillin 2b	0.012
cldn5a	claudin 5a	0.012
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.012
tcf12	transcription factor 12	0.012
cryba2b	crystallin, beta A2b	0.011
gh1	growth hormone 1	0.011
frem3	Fras1 related extracellular matrix 3	0.011
six4a	sine oculis homeobox homolog 4a	0.011
ctsl1b	cathepsin L, 1 b	0.011
znf703	zinc finger protein 703	0.011
ctnnd2b	catenin (cadherin-associated protein), delta 2b	0.011
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.011
foxd3	forkhead box D3	0.011	Zebrafish
irx5a	iroquois homeobox protein 5a	0.011
dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.011
hoxb3a	homeo box B3a	0.011
neurod4	neurogenic differentiation 4	0.011
fn1	fibronectin 1	0.010
slc7a6	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6	0.010
ier5l	immediate early response 5-like	0.010
cav1	caveolin 1	0.010
sox19a	SRY-box containing gene 19a	0.010
grhl1	grainyhead-like 1 (Drosophila)	0.010
lgsn	lengsin, lens protein with glutamine synthetase domain	0.010