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Danio rerio

11 genes annotated in zebrafish

regulation of innate immune response

Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of innate immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of innate immune response" (in gray)

Name	Description	Probability	Func Analog Organism
nod1	nucleotide-binding oligomerization domain containing 1	0.774
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.593	Mouse
LOC557072	caspase recruitment domain-containing protein 11-like	0.522
ef1a	elongation factor 1-alpha	0.437
tlr21	toll-like receptor 21	0.427
tlr9	toll-like receptor 9	0.241
sgpl1	sphingosine-1-phosphate lyase 1	0.227
pycard	PYD and CARD domain containing	0.196	Human Mouse
tnfb	tumor necrosis factor b (TNF superfamily, member 2)	0.157
atf3	activating transcription factor 3	0.133
ripk2	receptor-interacting serine-threonine kinase 2	0.103
fn1b	fibronectin 1b	0.083
caspa	caspase a	0.080
copa	coatomer protein complex, subunit alpha	0.079
stc1l	stanniocalcin 1, like	0.070
pdlim1	PDZ and LIM domain 1 (elfin)	0.068
si:ch211-195h23.3	si:ch211-195h23.3	0.067
sh3gl1b	SH3-domain GRB2-like 1b	0.067
tlr18	toll-like receptor 18	0.066
ctgf	connective tissue growth factor	0.060
piwil1	piwi-like 1 (Drosophila)	0.060	Fly
fzd2	frizzled homolog 2	0.057
defbl3	defensin, beta-like 3	0.055
pdcd2	programmed cell death 2	0.055
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.054	Mouse
rhag	Rhesus blood group-associated glycoprotein	0.053
zgc:136878	zgc:136878	0.052
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.052
usp10	ubiquitin specific peptidase 10	0.049
cyp3a65	cytochrome P450, family 3, subfamily A, polypeptide 65	0.047
mstnb	myostatin b	0.046
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.042
sparc	secreted acidic cysteine rich glycoprotein	0.041
adrb2a	adrenergic receptor, beta 2a	0.040
adra2a	adrenergic, alpha-2A-, receptor	0.040	Worm
gng2	guanine nucleotide binding protein (G protein), gamma 2	0.040
LOC100534776	toll-like receptor 7-like	0.039
fmnl2b	formin-like 2b	0.039
tlr4bb	toll-like receptor 4b, duplicate b	0.038	Human Mouse
card9	caspase recruitment domain family, member 9	0.037	Mouse
pyya	peptide YYa	0.036
vasa	vasa homolog	0.036
LOC100000934	hypothetical protein LOC100000934	0.036
sult2st1	sulfotransferase family 2, cytosolic sulfotransferase 1	0.035
epor	erythropoietin receptor	0.035
tirap	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.034
eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.033
ighz	immunoglobulin heavy constant zeta	0.033
socs1	suppressor of cytokine signaling 1	0.032
LOC100151531	zinc finger protein Gfi-1b-like	0.030
card14	caspase recruitment domain family, member 14	0.030
hmox1	heme oxygenase (decycling) 1	0.029
tfe3b	transcription factor binding to IGHM enhancer 3b	0.028
mpx	myeloid-specific peroxidase	0.027
fgfr3	fibroblast growth factor receptor 3	0.027	Fly
col15a1a	collagen, type XV, alpha 1a	0.026
tlr2	toll-like receptor 2	0.026	Mouse
si:ch211-212m21.5	si:ch211-212m21.5	0.025	Human
itln3	intelectin 3	0.025
itm2bb	integral membrane protein 2Bb	0.025
vtg1	vitellogenin 1	0.024
boc	brother of CDO	0.024
pitpna	phosphatidylinositol transfer protein, alpha	0.024
shbg	sex hormone binding globulin	0.024
junb	jun B proto-oncogene	0.024
meis1	myeloid ecotropic viral integration 1	0.023
hspa9	heat shock protein 9	0.023
irf11	interferon regulatory factor 11	0.023
otul	OTU like protein	0.023
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.022
cyp51	cytochrome P450, family 51	0.022
sp2	sp2 transcription factor	0.022
efna2	ephrin A2	0.021
pglyrp5	peptidoglycan recognition protein 5	0.021
fibpl	fibroblast growth factor (acidic) intracellular binding protein, like	0.020
lpp	LIM domain containing preferred translocation partner in lipoma	0.020
cx35	connexin 35	0.020
il6r	interleukin 6 receptor	0.020
tmprss4a	transmembrane protease, serine 4a	0.020
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.019
ticam1	toll-like receptor adaptor molecule 1	0.019	Mouse
tlr3	toll-like receptor 3	0.019	Human
serinc2	serine incorporator 2	0.019
si:dkeyp-110g5.2	si:dkeyp-110g5.2	0.019	Human
lsr	lipolysis stimulated lipoprotein receptor	0.019
si:dkey-76b14.4	si:dkey-76b14.4	0.018
zgc:101598	zgc:101598	0.018
adra2b	adrenergic, alpha-2B-, receptor	0.018	Worm
irf9	interferon regulatory factor 9	0.018
rpl37	ribosomal protein L37	0.018
ip6k2	inositol hexaphosphate kinase 2	0.018
cyt1	type I cytokeratin, enveloping layer	0.017
eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	0.017
spint1a	serine peptidase inhibitor, Kunitz type 1 a	0.017
krit1	KRIT1, ankyrin repeat containing	0.017
lipc	lipase, hepatic	0.017
copg2	coatomer protein complex, subunit gamma 2	0.016
cd40lg	CD40 ligand	0.016
il8	interleukin 8	0.016
zmynd11	zinc finger, MYND domain containing 11	0.016
traf6	TNF receptor-associated factor 6	0.016
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.016
ikbkg	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.016
snx8	sorting nexin 8	0.016
stat3	signal transduction and activation of transcription 3	0.016
ctnnb1	catenin (cadherin-associated protein), beta 1	0.016
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.015
bhmt	betaine-homocysteine methyltransferase	0.015
emx3	empty spiracles homeobox 3	0.015
smyd3	SET and MYND domain containing 3	0.015
c1qa	complement component 1, q subcomponent, A chain	0.015
vipr2	vasoactive intestinal peptide receptor 2	0.015
igf1	insulin-like growth factor 1	0.015
hdr	hematopoietic death receptor	0.015
zgc:171553	zgc:171553	0.014
nr3c2	nuclear receptor subfamily 3, group C, member 2	0.014
epas1b	endothelial PAS domain protein 1b	0.014
tbx21	T-box 21	0.014
ahsg	alpha-2-HS-glycoprotein	0.014
c1qc	complement component 1, q subcomponent, C chain	0.014
kpna3	karyopherin (importin) alpha 3	0.014
c1qb	complement component 1, q subcomponent, B chain	0.014
ecscr	endothelial cell-specific chemotaxis regulator	0.014
nitr13	novel immune-type receptor 13	0.013
slc2a13	solute carrier family 2 (facilitated glucose transporter), member 13	0.013
hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.013
f5	coagulation factor V	0.013
illr1	immune-related, lectin-like receptor 1	0.013	Zebrafish
cpne1	copine I	0.013
elovl1b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b	0.013
zp2l2	zona pellucida glycoprotein 2, like 2	0.013
illr4	immune-related, lectin-like receptor 4	0.013	Zebrafish
abcb7	ATP-binding cassette, sub-family B (MDR/TAP), member 7	0.012
calcrla	calcitonin receptor-like a	0.012
ca15a	carbonic anhydrase XV a	0.012
ptch2	patched 2	0.012
zgc:153096	zgc:153096	0.012
ighz2	immunoglobulin heavy constant zeta2	0.012
itln1	intelectin 1	0.012
msi1	musashi homolog 1 (Drosophila)	0.012
cd40	CD40 antigen	0.012
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.012
pcsk9	proprotein convertase subtilisin/kexin type 9	0.012
chuk	conserved helix-loop-helix ubiquitous kinase	0.012	Fly
si:dkey-250d21.1	si:dkey-250d21.1	0.012
lpin1	lipin 1	0.011
LOC100536021	spectrin beta chain, brain 1-like	0.011
c3b	complement component c3b	0.011
tlr4ba	toll-like receptor 4b, duplicate a	0.011	Human Mouse Rat
jak1	Janus kinase 1	0.011
mpzl2	myelin protein zero-like 2	0.011
fabp2	fatty acid binding protein 2, intestinal	0.011
LOC100537975	thyroid receptor-interacting protein 11-like	0.011
il6st	interleukin 6 signal transducer	0.011
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.011
paqr7b	progestin and adipoQ receptor family member VII, b	0.011
thoc2	THO complex 2	0.010
pcsk2	proprotein convertase subtilisin/kexin type 2	0.010
pygb	phosphorylase, glycogen; brain	0.010
tlr20a	toll-like receptor 20a	0.010
sfrp5	secreted frizzled-related protein 5	0.010
gsk3b	glycogen synthase kinase 3 beta	0.010
LOC100004946	transient receptor potential cation channel subfamily M member 4-like	0.010
cav1	caveolin 1	0.010
cd209	CD209 molecule	0.010	Zebrafish
acvr2a	activin receptor IIa	0.010
mc2r	melanocortin 2 receptor	0.010
pth1a	parathyroid hormone 1a	0.010
igf3	insulin-like growth factor 3	0.010