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Danio rerio

2 genes annotated in zebrafish

regulation of sarcomere organization

Any process that modulates the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of sarcomere organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of sarcomere organization" (in gray)

Name	Description	Probability	Func Analog Organism
smyd1b	SET and MYND domain containing 1b	0.999	Zebrafish
mef2cb	myocyte enhancer factor 2cb	0.994	Mouse
mef2ca	myocyte enhancer factor 2ca	0.991	Mouse
myhz1.1	myosin, heavy polypeptide 1.1, skeletal muscle	0.989	Mouse
myhz2	myosin, heavy polypeptide 2, fast muscle specific	0.960	Mouse
chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1	0.954
myog	myogenin	0.919
tnnc1b	troponin C type 1b (slow)	0.889
smyhc1	slow myosin heavy chain 1	0.885
unc45b	unc-45 homolog B (C. elegans)	0.762
myod1	myogenic differentiation 1	0.711
fabp11a	fatty acid binding protein 11a	0.693
actn3a	actinin alpha 3a	0.522
myhc4	myosin heavy chain 4	0.449	Mouse
ryr3	ryanodine receptor 3	0.408
tnni1b	troponin I, skeletal, slow b	0.340
pdlim7	PDZ and LIM domain 7	0.282
smyd2a	SET and MYND domain containing 2a	0.268
ttna	titin a	0.263
ryr1b	ryanodine receptor 1b (skeletal)	0.242
ckma	creatine kinase, muscle a	0.207
tbx5a	T-box 5a	0.203
mstna	myostatin a	0.198
smyd1a	SET and MYND domain containing 1a	0.187	Zebrafish
popdc2	popeye domain containing 2	0.184
hsp90a.1	heat shock protein 90-alpha 1	0.169
mylz2	myosin, light polypeptide 2, skeletal muscle	0.163
stac3	SH3 and cysteine rich domain 3	0.159
pikfyve	phosphoinositide kinase, FYVE finger containing	0.140
xirp1	xin actin-binding repeat containing 1	0.119
vgll2b	vestigial like 2b	0.102
ndrg4	N-myc downstream regulated gene 4	0.097
lama2	laminin, alpha 2	0.094
tgfb3	transforming growth factor, beta 3	0.092
flncb	filamin C, gamma b (actin binding protein 280)	0.092
hspb1	heat shock protein, alpha-crystallin-related, 1	0.084
tpma	alpha-tropomyosin	0.083
fabp3	fatty acid binding protein 3, muscle and heart	0.072
xirp2a	xin actin-binding repeat containing 2a	0.065
lepr	leptin receptor	0.064
fhla	four and a half LIM domains a	0.061
rnasel1	ribonuclease like 1	0.056
hspd1	heat shock 60kD protein 1 (chaperonin)	0.047
rbm24a	RNA binding motif protein 24a	0.046
vmhc	ventricular myosin heavy chain	0.045
lbx2	ladybird homeobox homolog 2 (Drosophila)	0.045
dmrt2b	doublesex and mab-3 related transcription factor 2b	0.042
actn2	actinin, alpha 2	0.039
lamb2	laminin, beta 2 (laminin S)	0.039
six1b	sine oculis homeobox homolog 1b	0.037
tbx20	T-box 20	0.037
rnf41	ring finger protein 41	0.036
apobec2a	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a	0.035
desma	desmin a	0.033
actn3b	actinin alpha 3b	0.032
tnnt1	troponin T1, skeletal, slow	0.031
LOC557072	caspase recruitment domain-containing protein 11-like	0.027
tnni1al	troponin I, skeletal, slow like	0.027
col2a1a	collagen type II, alpha-1a	0.026
map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.025
park7	parkinson disease (autosomal recessive, early onset) 7	0.024
flot1	flotillin 1	0.024
synpo2lb	synaptopodin 2-like b	0.023
sec61b	Sec61 beta subunit	0.023
myf5	myogenic factor 5	0.023
jam2a	junctional adhesion molecule 2a	0.023
mecom	MDS1 and EVI1 complex locus	0.022
LOC100149148	novel protein similar to myosin heavy chain 4 (myhc4)	0.021
acta1a	actin, alpha 1a, skeletal muscle	0.021
LOC100006361	galanin-like	0.020
tfr1a	transferrin receptor 1a	0.020
gfer	growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)	0.019
me2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.018
nsd1b	nuclear receptor binding SET domain protein 1b	0.017
nexn	nexilin (F actin binding protein)	0.017
mylipa	myosin regulatory light chain interacting protein a	0.017
mef2d	myocyte enhancer factor 2d	0.017
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.017
mbnl2	muscleblind-like 2 (Drosophila)	0.017
myl1	myosin, light chain 1, alkali; skeletal, fast	0.016
scinla	scinderin like a	0.016
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.016
tbx5b	T-box 5b	0.015
smyd2b	SET and MYND domain containing 2b	0.015	Zebrafish
lgi1b	leucine-rich, glioma inactivated 1b	0.015
stmn2b	stathmin-like 2b	0.014
epor	erythropoietin receptor	0.014
actn1	actinin, alpha 1	0.014
ckmt2	creatine kinase, mitochondrial 2 (sarcomeric)	0.014
slc39a1	solute carrier family 39 (zinc transporter), member 1	0.014
mybpc3	myosin binding protein C, cardiac	0.014
myhz1.2	myosin, heavy polypeptide 1.2, skeletal muscle	0.014
vegfaa	vascular endothelial growth factor Aa	0.014
sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.013
wu:fv91b12	wu:fv91b12	0.013
scn4ab	sodium channel, voltage-gated, type IV, alpha, b	0.013
alcama	activated leukocyte cell adhesion molecule a	0.013
ryr1a	ryanodine receptor 1a (skeletal)	0.012
LOC566969	similar to MOX-2 protein	0.012
eng1a	engrailed 1a	0.012
si:dkey-228g21.4	si:dkey-228g21.4	0.012
atp2a2a	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a	0.012
pdlim2	PDZ and LIM domain 2 (mystique)	0.012
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.012
setd8b	SET domain containing (lysine methyltransferase) 8b	0.012
zgc:56630	zgc:56630	0.012
thrb	thyroid hormone receptor beta	0.011
zgc:113210	zgc:113210	0.011
nr5a2	nuclear receptor subfamily 5, group A, member 2	0.011
hbae1	hemoglobin alpha embryonic-1	0.011
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.011
tspan18a	tetraspanin 18a	0.011
smyhc2	slow myosin heavy chain 2	0.011
scn1ba	sodium channel, voltage-gated, type I, beta a	0.011
stc1l	stanniocalcin 1, like	0.011
zgc:92666	zgc:92666	0.010
lmbrd2b	LMBR1 domain containing 2b	0.010