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Process View

Danio rerio

5 genes annotated in zebrafish

spindle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "spindle organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "spindle organization" (in gray)

Name	Description	Probability	Func Analog Organism
top2a	topoisomerase (DNA) II alpha	0.514	Fly
rps29	ribosomal protein S29	0.444
rpl12	ribosomal protein L12	0.192	Fly
rps5	ribosomal protein S5	0.166	Fly
smc4	structural maintenance of chromosomes 4	0.147
rps3a	ribosomal protein S3A	0.142	Fly
pde6c	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	0.109
wu:fi04f09	wu:fi04f09	0.101
kif23	kinesin family member 23	0.079	Human Worm Fly
ahctf1	AT hook containing transcription factor 1	0.075
rpl23a	ribosomal protein L23a	0.072
rplp0	ribosomal protein, large, P0	0.069
rpl13	ribosomal protein L13	0.069	Fly
ccnb1	cyclin B1	0.067	Human
aurkb	aurora kinase B	0.066	Yeast Worm
u2af1	U2(RNU2) small nuclear RNA auxiliary factor 1	0.063	Fly
runx1	runt-related transcription factor 1	0.060
cmyb	transcription factor cmyb	0.059	Fly
zgc:112425	zgc:112425	0.058
lamc1	laminin, gamma 1	0.056
rps11	ribosomal protein S11	0.053	Fly
axin1	axin 1	0.053	Worm
rps15a	ribosomal protein S15a	0.053	Fly
egr1	early growth response 1	0.049
rpl8	ribosomal protein L8	0.048
rpl3	ribosomal protein L3	0.047	Fly
birc5b	baculoviral IAP repeat-containing 5B	0.044
si:ch211-156j22.4	si:ch211-156j22.4	0.042
rpl7	ribosomal protein L7	0.040	Fly
rpl35	ribosomal protein L35	0.040	Fly
mybl2	myeloblastosis oncogene-like 2	0.038	Mouse Fly
si:ch211-69g19.2	si:ch211-69g19.2	0.037
ccna2	cyclin A2	0.037
rps12	ribosomal protein S12	0.036
rpl19	ribosomal protein L19	0.034	Fly
prkci	protein kinase C, iota	0.033
zgc:92237	zgc:92237	0.033
wu:fl55e11	wu:fl55e11	0.033
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.029
rps3	ribosomal protein S3	0.028
brd2a	bromodomain-containing 2a	0.028
rps7	ribosomal protein S7	0.028
sass6	spindle assembly 6 homolog (C. elegans)	0.027
cct6a	chaperonin containing TCP1, subunit 6A (zeta 1)	0.026
eef1g	eukaryotic translation elongation factor 1 gamma	0.025
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.025	Worm Fly
pabpc1a	poly A binding protein, cytoplasmic 1 a	0.024
efnb2a	ephrin B2a	0.024
psma8	proteasome (prosome, macropain) subunit, alpha type, 8	0.024
snx5	sorting nexin 5	0.023
ptch2	patched 2	0.023
rps18	ribosomal protein S18	0.022	Fly
khdrbs1b	KH domain containing, RNA binding, signal transduction associated 1b	0.021
rpl6	ribosomal protein L6	0.021
rps10	ribosomal protein S10	0.021
rps2	ribosomal protein S2	0.021
cct8	chaperonin containing TCP1, subunit 8 (theta)	0.020
snrpc	small nuclear ribonucleoprotein polypeptide C	0.020
psmc3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.019
birc5a	baculoviral IAP repeat-containing 5a	0.019
rpsa	ribosomal protein SA	0.019	Fly
LOC100536090	targeting protein for Xklp2-B-like	0.018
zgc:77702	zgc:77702	0.018
smad2	MAD homolog 2 (Drosophila)	0.018
glulb	glutamate-ammonia ligase (glutamine synthase) b	0.018
tie1	endothelium-specific receptor tyrosine kinase 1	0.018
gli1	GLI-Kruppel family member 1	0.018	Worm
ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.017	Human
gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.016
rpl18a	ribosomal protein L18a	0.016	Fly
apc	adenomatosis polyposis coli	0.016
pbx4	pre-B-cell leukemia transcription factor 4	0.016
fbl	fibrillarin	0.016
zgc:55461	zgc:55461	0.016
ccnb2	cyclin B2	0.015
zgc:123327	zgc:123327	0.015	Fly
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.015
ptbp1b	polypyrimidine tract binding protein 1b	0.015
nup93	nucleoporin 93	0.015
rps9	ribosomal protein S9	0.014
sf3b5	splicing factor 3b, subunit 5	0.014	Fly
ptch1	patched 1	0.014
mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.014
zgc:66100	zgc:66100	0.014
cdc20	cell division cycle 20 homolog	0.014
buc	bucky ball	0.014
rplp1	ribosomal protein, large, P1	0.013
nusap1	nucleolar and spindle associated protein 1	0.013
rpl10	ribosomal protein L10	0.013
sf3b1	splicing factor 3b, subunit 1	0.013
rpl35a	ribosomal protein L35a	0.013
si:ch211-215h6.2	si:ch211-215h6.2	0.013
skp2	S-phase kinase-associated protein 2 (p45)	0.013
kif11	kinesin family member 11	0.013	Human Worm Fly
ruvbl2	RuvB-like 2 (E. coli)	0.013
rpl28	ribosomal protein L28	0.013	Fly
gsna	gelsolin a	0.012
notch3	notch homolog 3	0.012
ncapg	non-SMC condensin I complex, subunit G	0.012
psmb3	proteasome (prosome, macropain) subunit, beta type, 3	0.012
crb2a	crumbs homolog 2a	0.012
LOC554173	abnormal spindles	0.012
nolc1	nucleolar and coiled-body phosphoprotein 1	0.012
rpl36a	ribosomal protein L36A	0.012	Fly
aurka	aurora kinase A	0.012	Human Yeast Mouse Worm
ythdf1	YTH domain family, member 1	0.011
rps8a	ribosomal protein S8a	0.011
rpl10a	ribosomal protein L10a	0.011	Fly
rpl4	ribosomal protein L4	0.011
rps15	ribosomal protein S15	0.011	Fly
nup107	nucleoporin 107	0.011
rpl7a	ribosomal protein L7a	0.011	Fly
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.010
supt6h	suppressor of Ty 6 homolog	0.010
eif5a	eukaryotic translation initiation factor 5A	0.010
map2k4a	mitogen-activated protein kinase kinase 4a	0.010
ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.010
stil	TAL1 (SCL) interrupting locus	0.010
rpl24	ribosomal protein L24	0.010	Fly
rpl34	ribosomal protein L34	0.010
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.010
rpl36	ribosomal protein L36	0.010
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.010
strap	serine/threonine kinase receptor associated protein	0.010