IMP
Process View
trigeminal nerve development
The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "trigeminal nerve development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| dlx2a | distal-less homeobox gene 2a | 0.978 | ||
| dlx6a | distal-less homeobox gene 6a | 0.758 | Zebrafish | |
| nrp1a | neuropilin 1a | 0.709 | Mouse | |
| dlx4a | distal-less homeobox gene 4a | 0.699 | Zebrafish | |
| dlx1a | distal-less homeobox gene 1a | 0.693 | Zebrafish | |
| dlx4b | distal-less homeobox gene 4b | 0.565 | ||
| dlx3b | distal-less homeobox gene 3b | 0.520 | ||
| dlx2b | distal-less homeobox gene 2b | 0.485 | Zebrafish | |
| sp8a | sp8 transcription factor a | 0.474 | ||
| dla | deltaA | 0.439 | ||
| sox10 | SRY-box containing gene 10 | 0.439 | ||
| sox9a | SRY-box containing gene 9a | 0.432 | ||
| dld | deltaD | 0.364 | ||
| sema3d | semaphorin 3d | 0.364 | ||
| nrp2b | neuropilin 2b | 0.272 | Mouse | |
| lhx6 | LIM homeobox 6 | 0.214 | ||
| insm1a | insulinoma-associated 1a | 0.203 | ||
| dlx5a | distal-less homeobox gene 5a | 0.190 | Zebrafish | |
| flot1 | flotillin 1 | 0.188 | ||
| isl2a | islet2a | 0.183 | ||
| elavl3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.145 | ||
| antxr1 | anthrax toxin receptor 1 | 0.133 | ||
| crestin | crestin | 0.119 | ||
| nrp1b | neuropilin 1b | 0.094 | Mouse | |
| dmbx1a | diencephalon/mesencephalon homeobox 1a | 0.092 | ||
| tfec | transcription factor EC | 0.092 | ||
| dzip1 | DAZ interacting protein 1 | 0.088 | ||
| pax9 | paired box gene 9 | 0.076 | ||
| insm1b | insulinoma-associated 1b | 0.071 | ||
| boc | brother of CDO | 0.068 | ||
| emx3 | empty spiracles homeobox 3 | 0.064 | ||
| barhl2 | BarH-like 2 | 0.061 | ||
| plxna3 | plexin A3 | 0.060 | Mouse | |
| six4a | sine oculis homeobox homolog 4a | 0.058 | ||
| nr4a2b | nuclear receptor subfamily 4, group A, member 2b | 0.057 | ||
| mib | mind bomb | 0.053 | ||
| cntn2 | contactin 2 | 0.052 | ||
| pax2a | paired box gene 2a | 0.051 | ||
| p2rx3a | purinergic receptor P2X, ligand-gated ion channel, 3a | 0.051 | ||
| her6 | hairy-related 6 | 0.050 | ||
| slit3 | slit (Drosophila) homolog 3 | 0.050 | ||
| itga5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.049 | ||
| sema3aa | semaphorin 3aa | 0.047 | Mouse | |
| nadl1.1 | neural adhesion molecule L1.1 | 0.046 | ||
| hdac4 | histone deacetylase 4 | 0.046 | ||
| fras1 | Fraser syndrome 1 | 0.044 | ||
| runx3 | runt-related transcription factor 3 | 0.043 | ||
| arx | aristaless related homeobox | 0.043 | ||
| foxp2 | forkhead box P2 | 0.042 | ||
| msxd | muscle segment homeobox D | 0.042 | ||
| nkx3.2 | NK3 homeobox 2 | 0.040 | ||
| msxe | muscle segment homeobox E | 0.039 | ||
| disp1 | dispatched homolog 1 (Drosophila) | 0.037 | ||
| pitx3 | paired-like homeodomain transcription factor 3 | 0.036 | ||
| tcf7l1a | transcription factor 7-like 1a (T-cell specific, HMG-box) | 0.036 | ||
| tpbgl | trophoblast glycoprotein-like | 0.035 | ||
| wu:fq26c12 | wu:fq26c12 | 0.034 | ||
| pitx2 | paired-like homeodomain transcription factor 2 | 0.034 | ||
| pcdh10b | protocadherin 10b | 0.033 | ||
| phox2b | paired-like homeobox 2b | 0.033 | ||
| zgc:112355 | zgc:112355 | 0.033 | ||
| hoxa3a | homeo box A3a | 0.033 | ||
| emx2 | empty spiracles homeobox 2 | 0.032 | ||
| acana | aggrecan a | 0.032 | ||
| pax6a | paired box gene 6a | 0.032 | ||
| rx3 | retinal homeobox gene 3 | 0.031 | ||
| robo3 | roundabout homolog 3 | 0.031 | ||
| fgf20a | fibroblast growth factor 20a | 0.031 | ||
| th2 | tyrosine hydroxylase 2 | 0.030 | ||
| skia | nuclear oncoprotein skia | 0.030 | ||
| nkx2.3 | NK2 transcription factor related 3 | 0.029 | ||
| sema3e | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.029 | ||
| col14a1 | collagen, type XIV, alpha 1 | 0.029 | ||
| ntn1b | netrin 1b | 0.029 | ||
| six2a | sine oculis-related homeobox 2a | 0.028 | ||
| scrt2 | scratch homolog 2, zinc finger protein (Drosophila) | 0.028 | ||
| fezf2 | FEZ family zinc finger 2 | 0.028 | ||
| wu:fi18a01 | wu:fi18a01 | 0.027 | ||
| mafba | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) | 0.027 | ||
| tbx24 | T-box 24 | 0.026 | ||
| rarga | retinoic acid receptor gamma a | 0.025 | ||
| tgfb2 | transforming growth factor, beta 2 | 0.025 | ||
| onecutl | one cut domain, family member, like | 0.025 | ||
| fzd9b | frizzled homolog 9b | 0.025 | ||
| cd99l2 | CD99 antigen-like 2 | 0.025 | ||
| zgc:85975 | zgc:85975 | 0.025 | ||
| hapln3 | hyaluronan and proteoglycan link protein 3 | 0.024 | ||
| pcdh17 | protocadherin 17 | 0.024 | ||
| zic1 | zic family member 1 (odd-paired homolog, Drosophila) | 0.024 | ||
| wu:fv91b12 | wu:fv91b12 | 0.023 | ||
| chat | choline acetyltransferase | 0.023 | ||
| six3a | sine oculis homeobox homolog 3a | 0.023 | ||
| nadl1.2 | neural adhesion molecule L1.2 | 0.023 | ||
| prickle1b | prickle homolog 1 (Drosophila) b | 0.023 | ||
| sim1a | single-minded homolog 1a (Drosophila) | 0.023 | ||
| tlx2 | T-cell leukemia, homeobox 2 | 0.023 | ||
| fgf24 | fibroblast growth factor 24 | 0.023 | ||
| fli1a | friend leukemia integration 1a | 0.022 | ||
| twist1a | twist1a | 0.022 | ||
| six4b | sine oculis homeobox homolog 4b | 0.022 | ||
| tgfb3 | transforming growth factor, beta 3 | 0.022 | ||
| otx1b | orthodenticle homolog 1b | 0.022 | ||
| pax7b | paired box gene 7b | 0.022 | ||
| tbx22 | T-box 22 | 0.022 | ||
| pax6b | paired box gene 6b | 0.021 | ||
| tal1 | T-cell acute lymphocytic leukemia 1 | 0.021 | ||
| otpa | orthopedia homolog a | 0.021 | ||
| tfap2c | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.021 | ||
| vegfc | vascular endothelial growth factor c | 0.021 | ||
| myf5 | myogenic factor 5 | 0.021 | ||
| foxa1 | forkhead box A1 | 0.020 | ||
| nfasca | neurofascin homolog (chicken) a | 0.020 | ||
| alcama | activated leukocyte cell adhesion molecule a | 0.020 | ||
| tgfbi | transforming growth factor, beta-induced | 0.019 | ||
| fgfr2 | fibroblast growth factor receptor 2 | 0.019 | ||
| shha | sonic hedgehog a | 0.019 | ||
| vangl2 | vang-like 2 (van gogh, Drosophila) | 0.019 | ||
| jam2b | junctional adhesion molecule 2b | 0.019 | ||
| efnb2a | ephrin B2a | 0.019 | ||
| slc17a6b | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b | 0.019 | ||
| chrna4 | cholinergic receptor, nicotinic, alpha 4 | 0.019 | ||
| olig2 | oligodendrocyte lineage transcription factor 2 | 0.019 | ||
| sb:cb979 | sb:cb979 | 0.019 | ||
| gcm2 | glial cells missing homolog 2 (Drosophila) | 0.018 | ||
| fgf10a | fibroblast growth factor 10a | 0.018 | ||
| lhx3 | LIM homeobox 3 | 0.018 | ||
| six3b | sine oculis homeobox homolog 3b | 0.018 | ||
| runx1 | runt-related transcription factor 1 | 0.018 | ||
| hapln1a | hyaluronan and proteoglycan link protein 1a | 0.018 | ||
| efna2 | ephrin A2 | 0.018 | ||
| hs3st3b1b | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b | 0.018 | ||
| lingo1b | leucine rich repeat and Ig domain containing 1b | 0.018 | ||
| ptch1 | patched 1 | 0.018 | ||
| hoxd9a | homeo box D9a | 0.018 | ||
| cadm4 | cell adhesion molecule 4 | 0.017 | ||
| hoxb2a | homeo box B2a | 0.017 | ||
| olfm2 | olfactomedin 2 | 0.017 | ||
| col15a1b | collagen, type XV, alpha 1b | 0.017 | ||
| foxg1a | forkhead box G1a | 0.017 | ||
| cald1 | caldesmon 1 | 0.016 | ||
| enpp1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.016 | ||
| bmper | BMP binding endothelial regulator | 0.016 | ||
| sema3gb | semaphorin 3gb | 0.016 | ||
| cacnb3a | calcium channel, voltage-dependent, beta 3a | 0.016 | ||
| ephb4a | eph receptor B4a | 0.015 | ||
| ebf3 | early B-cell factor 3 | 0.015 | ||
| hand2 | heart and neural crest derivatives expressed transcript 2 | 0.015 | ||
| wisp1b | WNT1 inducible signaling pathway protein 1b | 0.015 | ||
| fgf16 | fibroblast growth factor 16 | 0.015 | ||
| p2rx3b | purinergic receptor P2X, ligand-gated ion channel, 3b | 0.015 | ||
| sumo2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.015 | ||
| mecom | MDS1 and EVI1 complex locus | 0.015 | ||
| nkx6.1 | NK6 transcription factor related, locus 1 (Drosophila) | 0.015 | ||
| stmn4 | stathmin-like 4 | 0.015 | ||
| p2rx2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.015 | ||
| par1 | paraxis | 0.014 | ||
| pcdh10a | protocadherin 10a | 0.014 | ||
| egr2b | early growth response 2b | 0.014 | ||
| ndel1a | nudE nuclear distribution gene E homolog like 1 (A. nidulans) A | 0.014 | ||
| dlb | deltaB | 0.014 | ||
| edn1 | endothelin 1 | 0.014 | ||
| ek1 | eph-like kinase 1 | 0.014 | ||
| six1a | sine oculis homeobox homolog 1a | 0.014 | ||
| plekhh1 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 | 0.014 | ||
| tcf21 | transcription factor 21 | 0.014 | ||
| dap1b | death associated protein 1b | 0.014 | ||
| sp7 | Sp7 transcription factor | 0.013 | ||
| hic1 | hypermethylated in cancer 1 | 0.013 | ||
| irx5a | iroquois homeobox protein 5a | 0.013 | ||
| sema3c | semaphorin 3c | 0.013 | ||
| smoc1 | SPARC related modular calcium binding 1 | 0.013 | ||
| hlxb9lb | homeo box HB9 like b | 0.013 | ||
| sb:cb774 | sb:cb774 | 0.013 | ||
| hoxa9a | homeo box A9a | 0.013 | ||
| jhdm1da | jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae) | 0.013 | ||
| mnx1 | motor neuron and pancreas homeobox 1 | 0.013 | ||
| tcf7 | transcription factor 7 (T-cell specific, HMG-box) | 0.012 | ||
| mapk4 | mitogen-activated protein kinase 4 | 0.012 | ||
| col10a1 | collagen, type X, alpha 1 | 0.012 | ||
| vasp | vasodilator-stimulated phosphoprotein | 0.012 | ||
| zgc:92242 | zgc:92242 | 0.012 | ||
| lamb1a | laminin, beta 1a | 0.012 | ||
| prdm1a | PR domain containing 1a, with ZNF domain | 0.012 | ||
| iba57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) | 0.012 | ||
| barx1 | BarH-like homeobox 1 | 0.012 | ||
| slit2 | slit (Drosophila) homolog 2 | 0.012 | ||
| stmn2b | stathmin-like 2b | 0.012 | ||
| atl1 | atlastin GTPase 1 | 0.012 | ||
| mpp1 | membrane protein, palmitoylated 1 | 0.012 | ||
| zic4 | zic family member 4 | 0.012 | ||
| serinc5 | serine incorporator 5 | 0.012 | ||
| sulf1 | sulfatase 1 | 0.012 | ||
| plcb3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.012 | ||
| zdhhc8b | zinc finger, DHHC-type containing 8b | 0.012 | ||
| hoxb6a | homeo box B6a | 0.012 | ||
| tnc | tenascin C | 0.011 | ||
| sox2 | SRY-box containing gene 2 | 0.011 | ||
| xylt1 | xylosyltransferase 1 | 0.011 | ||
| hoxd11a | homeo box D11a | 0.011 | ||
| pcdh18b | protocadherin 18b | 0.011 | ||
| LOC569768 | metabotropic glutamate receptor 8-like | 0.011 | ||
| sox1a | SRY-box containing gene 1a | 0.011 | ||
| tmtc2 | transmembrane and tetratricopeptide repeat containing 2 | 0.011 | ||
| barx2 | BarH-like homeobox 2 | 0.011 | ||
| si:ch211-209p5.2 | si:ch211-209p5.2 | 0.011 | ||
| robo2 | roundabout homolog 2 | 0.011 | ||
| zgc:165626 | zgc:165626 | 0.011 | ||
| phox2a | paired-like homeobox 2a | 0.011 | ||
| nin | ninein (GSK3B interacting protein) | 0.011 | ||
| dpysl4 | dihydropyrimidinase-like 4 | 0.011 | ||
| and3 | actinodin3 | 0.011 | ||
| fstl1a | follistatin-like 1a | 0.011 | ||
| arl4cb | ADP-ribosylation factor-like 4Cb | 0.011 | ||
| bambia | BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a | 0.011 | ||
| nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.011 | ||
| flt4 | fms-related tyrosine kinase 4 | 0.010 | ||
| irx7 | iroquois homeobox protein 7 | 0.010 | ||
| mdkb | midkine-related growth factor b | 0.010 | ||
| calm1a | calmodulin 1a | 0.010 | ||
| sema3fb | semaphorin 3fb | 0.010 | Mouse | |
| racgap1 | Rac GTPase-activating protein 1 | 0.010 | ||
| neurog1 | neurogenin 1 | 0.010 | ||
| tph2 | tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) | 0.010 | ||
| tal2 | T-cell acute lymphocytic leukemia 2 | 0.010 | ||
| hlx1 | H2.0-like homeo box 1 (Drosophila) | 0.010 |