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Danio rerio

8 genes annotated in zebrafish

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defense response to gram negative bacterium

GO:0050829

Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "defense response to gram negative bacterium"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "defense response to gram negative bacterium" (in gray)

Name	Description	Probability	Func Analog Organism
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.227
atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.200
sh3gl1b	SH3-domain GRB2-like 1b	0.151
emx3	empty spiracles homeobox 3	0.141
crabp2a	cellular retinoic acid binding protein 2, a	0.118
igf1rb	insulin-like growth factor 1b receptor	0.107
npc1	Niemann-Pick disease, type C1	0.074
bmp7b	bone morphogenetic protein 7b	0.072
LOC557072	caspase recruitment domain-containing protein 11-like	0.064
fgfrl1b	fibroblast growth factor receptor-like 1b	0.064
tfe3b	transcription factor binding to IGHM enhancer 3b	0.059
tp53	tumor protein p53	0.058
fabp6	fatty acid binding protein 6, ileal (gastrotropin)	0.054
ctsl1a	cathepsin L, 1 a	0.050
nanos3	nanos homolog 3	0.049
cav1	caveolin 1	0.044
pparg	peroxisome proliferator activated receptor gamma	0.044
aqp10b	aquaporin 10b	0.044	Worm
caspa	caspase a	0.043
tlr3	toll-like receptor 3	0.043	Worm
aqp8a.2	aquaporin 8a, tandem duplicate 2	0.042
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.039
copa	coatomer protein complex, subunit alpha	0.038
cldn15a	claudin 15a	0.038
tlr9	toll-like receptor 9	0.037
notch3	notch homolog 3	0.037
aqp7	aquaporin 7	0.035	Worm
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.035
slc15a1b	solute carrier family 15 (oligopeptide transporter), member 1b	0.034
pycard	PYD and CARD domain containing	0.031	Human
axin2	axin 2 (conductin, axil)	0.030
duox	dual oxidase	0.029
tm4sf4	transmembrane 4 L six family member 4	0.029
nkx6.2	NK6 transcription factor related, locus 2	0.028
bmp2a	bone morphogenetic protein 2a	0.028
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.027
etv7	ets variant 7	0.024
rhoub	ras homolog gene family, member Ub	0.023
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.023
tm9sf1	transmembrane 9 superfamily member 1	0.023
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.023
aqp4	aquaporin 4	0.023
aqp11	aquaporin 11	0.022
tjp1	tight junction protein 1 (zona occludens 1)	0.022
hgfa	hepatocyte growth factor a	0.021
fam3c	family with sequence similarity 3, member C	0.021
nr1d2b	nuclear receptor subfamily 1, group D, member 2b	0.021
si:ch211-57k11.10	si:ch211-57k11.10	0.021
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.021
plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.021
ctsd	cathepsin D	0.020	Fly
rarga	retinoic acid receptor gamma a	0.020
igf1	insulin-like growth factor 1	0.020
runx2a	runt-related transcription factor 2a	0.020
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.019
calca	calcitonin/calcitonin-related polypeptide, alpha	0.019
cdx1b	caudal type homeobox 1 b	0.019
bmp3	bone morphogenetic protein 3	0.018
igf1ra	insulin-like growth factor 1a receptor	0.018
epas1b	endothelial PAS domain protein 1b	0.018
adipor1a	adiponectin receptor 1a	0.017
prdm5	PR domain containing 5	0.017
zgc:100919	zgc:100919	0.017
rpl37	ribosomal protein L37	0.017
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.016
pcsk7	proprotein convertase subtilisin/kexin type 7	0.016
fmr1	fragile X mental retardation 1	0.016
prnprs1	prion protein, related sequence 1	0.015
nos2a	nitric oxide synthase 2a, inducible	0.015
ins	preproinsulin	0.015
itpk1	inositol 1,3,4-triphosphate 5/6 kinase	0.015
LOC100005283	Gig2-like protein DreE	0.015
mtp	microsomal triglyceride transfer protein	0.015
zgc:171553	zgc:171553	0.015
il1b	interleukin 1, beta and interleukin 1, beta	0.014
smc1al	structural maintenance of chromosomes 1A, like	0.014
spns1	spinster homolog 1 (Drosophila)	0.014
gata6	GATA-binding protein 6	0.013
wnt9b	wingless-type MMTV integration site family, member 9B	0.013
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.013
LOC100332039	ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like	0.013
fzd5	frizzled homolog 5	0.013
LOC100005232	Gig2-like protein DreD	0.012
nkx2.2a	NK2 transcription factor related 2a	0.012
cpne1	copine I	0.012
hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.012
rnasel1	ribonuclease like 1	0.012
vtg6	vitellogenin 6	0.012
slc9a3.2	solute carrier family 9 (sodium/hydrogen exchanger), member 3.2	0.012
si:ch73-178d14.1	si:ch73-178d14.1	0.012
prkd1	protein kinase D1	0.012
cdk8	cyclin-dependent kinase 8	0.012
ighz2	immunoglobulin heavy constant zeta2	0.012
elnb	elastin b	0.011
ctsc	cathepsin C	0.011
cox7c	cytochrome c oxidase, subunit VIIc	0.011
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.011
fgf20a	fibroblast growth factor 20a	0.011
phf2	PHD finger protein 2	0.011
ptpra	protein tyrosine phosphatase, receptor type, A	0.011
cldn15la	claudin 15-like a	0.010
mc2r	melanocortin 2 receptor	0.010
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.010
tmem106a	transmembrane protein 106A	0.010
hdac4	histone deacetylase 4	0.010
ssrp1b	structure specific recognition protein 1b	0.010
zbtb4	zinc finger and BTB domain containing 4	0.010