The network for 'notch signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

notch signaling pathway

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

Name Description Probability Func Analog Organism
Su(H) Suppressor of Hairless 0.994
E(spl) Enhancer of split 0.993
HLHm7 E(spl) region transcript m7 0.974
HLHmgamma E(spl) region transcript mgamma 0.974
Psn Presenilin 0.943
HLHmdelta E(spl) region transcript mdelta 0.940
gbb glass bottom boat 0.939
N Notch 0.939
O-fut1 O-fucosyltransferase 1 0.923
mam mastermind 0.915
Tom Twin of m4 0.914
kuz kuzbanian 0.913
Gp150 CG5820 gene product from transcript CG5820-RA 0.908
m4 E(spl) region transcript m4 0.851
sca scabrous 0.801
lqfR liquid facets-Related 0.766
m2 E(spl) region transcript m2 0.765
HLHm5 E(spl) region transcript m5 0.761
ed echinoid 0.734
Notum CG13076 gene product from transcript CG13076-RB 0.688
malpha E(spl) region transcript malpha 0.671
fng fringe 0.656
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.636
ci cubitus interruptus 0.612
par-6 CG5884 gene product from transcript CG5884-RA 0.606
Vang Van Gogh 0.602
klar klarsicht 0.601
fu fused 0.589
hh hedgehog 0.552
ato atonal 0.547
nej nejire 0.541
sktl skittles 0.529
fj four-jointed 0.519
Crag Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein 0.495
cdi center divider 0.474
CtBP C-terminal Binding Protein 0.470
pbl pebble 0.467
gro groucho 0.457
stck steamer duck 0.415
CG9986 CG9986 gene product from transcript CG9986-RA 0.400
flr flare 0.380
ebi CG4063 gene product from transcript CG4063-RA 0.374
Vps35 Vacuolar protein sorting 35 0.370
Rab5 Rab-protein 5 0.364
nct nicastrin 0.360
CG9772 CG9772 gene product from transcript CG9772-RB 0.350
atl atlastin 0.349
ase asense 0.346
btd buttonhead 0.346
klu klumpfuss 0.345
amos absent MD neurons and olfactory sensilla 0.327
sina seven in absentia 0.321
HLHm3 E(spl) region transcript m3 0.313
Mi-2 CG8103 gene product from transcript CG8103-RA 0.312
Moe Moesin 0.303
sns sticks and stones 0.299
ft fat 0.293
stg string 0.286
Egfr Epidermal growth factor receptor 0.280
jumu jumeau 0.280
Eps-15 Epidermal growth factor receptor pathway substrate clone 15 0.278
Vps25 Vacuolar protein sorting 25 0.278
hbs hibris 0.272
Ten-m Tenascin major 0.268
disp dispatched 0.259
cindr CIN85 and CD2AP orthologue 0.259
sc scute 0.258
Arp14D Actin-related protein 14D 0.256
boi brother of iHog 0.256
Traf4 TNF-receptor-associated factor 4 0.254
H Hairless 0.249
dsh dishevelled 0.247
vps2 CG14542 gene product from transcript CG14542-RA 0.246
M6 CG7540 gene product from transcript CG7540-RA 0.241
Akt1 CG4006 gene product from transcript CG4006-RA 0.240
arr arrow 0.240
dpn deadpan 0.232
rpr reaper 0.226
mib1 mind bomb 1 0.225
Tsp3A Tetraspanin 3A 0.225
numb CG3779 gene product from transcript CG3779-RB 0.223
shn schnurri 0.223
ex expanded 0.220
yki yorkie 0.219
dia diaphanous 0.219
rst roughest 0.209
CG6116 CG6116 gene product from transcript CG6116-RA 0.208
wg wingless 0.203
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.202
hth homothorax 0.200
wls wntless 0.199
ac achaete 0.196
HLHmbeta E(spl) region transcript mbeta 0.193
aop anterior open 0.191
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.190
sav salvador 0.189
kibra kibra ortholog 0.181
RhoGAP100F CG1976 gene product from transcript CG1976-RB 0.181
lsn larsen 0.180
Rheb CG1081 gene product from transcript CG1081-RA 0.179
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.151
ehs-1 Protein EHS-1 0.082
sel-12 Protein SEL-12 0.073
pal-1 Protein PAL-1 0.071
lag-1 Protein LAG-1 0.064
igcm-3 Protein IGCM-3 0.051
eor-2 Protein EOR-2 0.044
CELE_M01B12.4 Protein M01B12.4 0.039
ten-1 Protein TEN-1 0.039
sel-8 Protein SEL-8 0.037
F10D7.5 Protein F10D7.5 0.031
vps-11 Protein VPS-11 0.027
bus-18 Protein BUS-18 0.026
che-13 Protein CHE-13 0.025
lag-2 Protein LAG-2 0.024
pha-4 Protein PHA-4 0.024
cki-2 Protein CKI-2 0.023
hnd-1 Protein HND-1 0.021
CELE_Y60A3A.9 Protein Y60A3A.9 0.021
dnj-25 Protein DNJ-25 0.021
tlf-1 Protein TLF-1 0.020
crml-1 Protein CRML-1 0.020
CELE_Y47G6A.18 Protein Y47G6A.18 0.020
nab-1 Protein NAB-1 0.019
C27C12.1 Protein C27C12.1 0.019
sur-2 Protein SUR-2 0.019
dab-1 Protein DAB-1 0.019
F52A8.1 Protein F52A8.1 0.019
dpy-26 Protein DPY-26 0.019
F23H11.4 Protein F23H11.4 0.018
eif-1.A Protein EIF-1.A 0.018
let-502 Protein LET-502 0.018
ubr-1 Protein UBR-1 0.018
C14A4.11 Protein C14A4.11 0.018
exoc-7 Protein EXOC-7 0.017
apb-1 Protein APB-1 0.017
lin-40 Protein LIN-40 0.017
figl-1 Protein FIGL-1 0.017
che-3 Protein CHE-3 0.017
pmp-3 Protein PMP-3 0.016
osm-3 Protein OSM-3 0.016
hlh-2 Protein HLH-2 0.016
lin-12 Protein LIN-12 0.016
mls-2 Protein MLS-2 0.016
zyg-1 Protein ZYG-1 0.015
let-60 Protein LET-60 0.015
tbx-33 Protein TBX-33 0.015
C31E10.6 Protein C31E10.6 0.015
imb-2 Protein IMB-2 0.015
rer-1 Protein RER-1 0.015
wdr-5.3 Protein WDR-5.3 0.015
helq-1 Protein HELQ-1 0.014
clh-6 Protein CLH-6 0.014
rab-35 Protein RAB-35 0.014
nath-10 Protein NATH-10 0.014
alx-1 Protein ALX-1 0.014
ndx-4 Protein NDX-4 0.014
ref-1 Protein REF-1 0.014
acl-14 Protein ACL-14 0.014
Y87G2A.7 Protein Y87G2A.7 0.014
nhr-67 Protein NHR-67 0.014
nra-3 Protein NRA-3 0.013
tag-353 Protein TAG-353 0.013
gfi-3 Protein GFI-3 0.013
npp-23 Protein NPP-23 0.013
ZK632.11 Protein ZK632.11 0.013
drap-1 Protein DRAP-1 0.013
tag-231 Protein TAG-231 0.013
inx-3 Protein INX-3 0.012
osm-6 Protein OSM-6 0.012
dre-1 Protein DRE-1 0.012
egl-30 Protein EGL-30 0.012
aps-2 Protein APS-2 0.012
htz-1 Protein HTZ-1 0.012
F43D9.1 Protein F43D9.1 0.012
C52E12.4 Protein C52E12.4 0.012
btbd-10 Protein BTBD-10 0.012
rps-1 Protein RPS-1 0.012
C02F5.13 Protein C02F5.13 0.012
cnd-1 Protein CND-1 0.012
kin-4 Protein KIN-4 0.012
sel-11 Protein SEL-11 0.012
unc-108 Protein UNC-108 0.012
erfa-3 Protein ERFA-3 0.012
cpt-1 Protein CPT-1 0.012
tag-77 Protein TAG-77 0.011
pho-5 Protein PHO-5 0.011
K10C9.3 Protein K10C9.3 0.011
ntl-2 Protein NTL-2 0.011
ocam-1 Protein OCAM-1 0.011
tbc-2 Protein TBC-2 0.011
C13B4.1 Protein C13B4.1 0.011
cit-1.1 Protein CIT-1.1 0.011
unc-53 Protein UNC-53 0.011
toca-1 Protein TOCA-1 0.011
D2030.4 Protein D2030.4 0.011
unc-32 Protein UNC-32 0.011
D2013.6 Protein D2013.6 0.011
Y44E3A.6 Protein Y44E3A.6 0.011
vang-1 Protein VANG-1 0.011
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Danio rerio
Name Description Probability Func Analog Organism
dla deltaA 0.828
mespb mesoderm posterior b 0.817
foxc1a forkhead box C1a 0.802
epb41l5 erythrocyte membrane protein band 4.1 like 5 0.666
wnt5b wingless-type MMTV integration site family, member 5b 0.630
notch1a notch homolog 1a 0.617
wnt11 wingless-type MMTV integration site family, member 11 0.365
axin2 axin 2 (conductin, axil) 0.334
dlc deltaC 0.329
her9 hairy-related 9 0.285
tbx16 T-box gene 16 0.251
wt1b wilms tumor 1b 0.246
wls wntless homolog (Drosophila) 0.237
mespa mesoderm posterior a 0.234
tfap2a transcription factor AP-2 alpha 0.234
crb2a crumbs homolog 2a 0.224
wu:fj39b01 wu:fj39b01 0.224
pea3 ETS-domain transcription factor pea3 0.204
gro2 groucho 2 0.197
il6r interleukin 6 receptor 0.186
ift88 intraflagellar transport 88 homolog 0.185
myf5 myogenic factor 5 0.180
cc2d2a coiled-coil and C2 domain containing 2A 0.175
her15.1 hairy and enhancer of split-related 15.1 0.174
her6 hairy-related 6 0.174
her1 hairy-related 1 0.173
chd chordin 0.169
tbx6 T-box gene 6 0.166
eya1 eyes absent homolog 1 0.162
kif17 kinesin family member 17 0.161
fzd10 frizzled homolog 10 0.153
pou5f1 POU domain, class 5, transcription factor 1 0.152
mib mind bomb 0.148
lfng lunatic fringe homolog 0.147
mmp2 matrix metalloproteinase 2 0.145
dlx5a distal-less homeobox gene 5a 0.139
actn1 actinin, alpha 1 0.137
sesn1 sestrin 1 0.134
ascl1b achaete-scute complex-like 1b (Drosophila) 0.127
nod1 nucleotide-binding oligomerization domain containing 1 0.127
flt4 fms-related tyrosine kinase 4 0.126
neurog1 neurogenin 1 0.125
dld deltaD 0.125
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.124
msxc muscle segment homeobox C 0.123
ephb4b eph receptor B4b 0.121
prkci protein kinase C, iota 0.119
dlb deltaB 0.118
sox3 SRY-box containing gene 3 0.116
meis1 myeloid ecotropic viral integration 1 0.115
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.111
six3b sine oculis homeobox homolog 3b 0.110
pak1 p21/Cdc42/Rac1-activated kinase 1 0.101
pard6gb par-6 partitioning defective 6 homolog gamma B (C. elegans) 0.100
lamb1a laminin, beta 1a 0.099
notch3 notch homolog 3 0.097
pitx3 paired-like homeodomain transcription factor 3 0.095
hlx1 H2.0-like homeo box 1 (Drosophila) 0.094
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.090
plekhg4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.083
pppde1 PPPDE peptidase domain containing 1 0.081
spint1a serine peptidase inhibitor, Kunitz type 1 a 0.081
ripply2 ripply2 0.079
nrarpa notch-regulated ankyrin repeat protein a 0.078
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.078
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.078
bmp2b bone morphogenetic protein 2b 0.074
sars seryl-tRNA synthetase 0.074
ephb4a eph receptor B4a 0.073
LOC100000500 sclerostin-like 0.071
her3 hairy-related 3 0.071
otx2 orthodenticle homolog 2 0.070
rx2 retinal homeobox gene 2 0.070
lamc1 laminin, gamma 1 0.069
hlxb9la homeo box HB9 like a 0.068
zgc:64040 zgc:64040 0.067
zmynd11 zinc finger, MYND domain containing 11 0.067
tm9sf2 transmembrane 9 superfamily member 2 0.067
gja3 gap junction protein, alpha 3 0.067
klf2a Kruppel-like factor 2a 0.066
ascl1a achaete-scute complex-like 1a (Drosophila) 0.065
vegfab vascular endothelial growth factor Ab 0.065
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.064
gyltl1b glycosyltransferase-like 1b 0.063
supt6h suppressor of Ty 6 homolog 0.063
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.063
jag1b jagged 1b 0.063
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.062
msi1 musashi homolog 1 (Drosophila) 0.062
fgf13b fibroblast growth factor 13b 0.062
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.062
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.062
vsx2 visual system homeobox 2 0.062
supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.061
src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.060
olig4 oligodendrocyte transcription factor 4 0.059
bactin2 bactin2 0.059
cdh2 cadherin 2, neuronal 0.058
zgc:112211 zgc:112211 0.057
hoxc6a homeo box C6a 0.057
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Homo sapiens
Name Description Probability Func Analog Organism
NOTCH1 notch 1 0.990
GRB2 growth factor receptor-bound protein 2 0.959
JAG1 jagged 1 0.895
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.833
EPS15 epidermal growth factor receptor pathway substrate 15 0.770
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.662
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.651
SH3KBP1 SH3-domain kinase binding protein 1 0.625
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.573
DVL2 dishevelled, dsh homolog 2 (Drosophila) 0.566
TAL1 T-cell acute lymphocytic leukemia 1 0.531
POU5F1 POU class 5 homeobox 1 0.511
HDAC1 histone deacetylase 1 0.510
NOTCH3 notch 3 0.491
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.477
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.458
ATP13A2 ATPase type 13A2 0.436
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.434
CP110 CP110 protein 0.366
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.355
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.328
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.309
SOS1 son of sevenless homolog 1 (Drosophila) 0.300
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.272
LAT linker for activation of T cells 0.269
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.256
CREBBP CREB binding protein 0.251
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.249
SMAD4 SMAD family member 4 0.231
MAGEA3 melanoma antigen family A, 3 0.219
ADAM10 ADAM metallopeptidase domain 10 0.212
DBNL drebrin-like 0.209
CSNK1E casein kinase 1, epsilon 0.199
LCK lymphocyte-specific protein tyrosine kinase 0.197
CDK6 cyclin-dependent kinase 6 0.190
SKIL SKI-like oncogene 0.189
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.182
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.182
CSNK1D casein kinase 1, delta 0.182
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.176
BMPR1A bone morphogenetic protein receptor, type IA 0.161
GRB7 growth factor receptor-bound protein 7 0.158
MAGEA6 melanoma antigen family A, 6 0.155
GDA guanine deaminase 0.151
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.146
NCOR1 nuclear receptor corepressor 1 0.145
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.144
DNM1 dynamin 1 0.140
FYN FYN oncogene related to SRC, FGR, YES 0.135
EGFR epidermal growth factor receptor 0.135
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.133
SPEN spen homolog, transcriptional regulator (Drosophila) 0.129
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.128
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.127
SMAD2 SMAD family member 2 0.125
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.124
TNIP1 TNFAIP3 interacting protein 1 0.124
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.124
NAP1L5 nucleosome assembly protein 1-like 5 0.123
CTAG1B cancer/testis antigen 1B 0.123
MAGEA12 melanoma antigen family A, 12 0.121
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.116
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.116
RUNX1 runt-related transcription factor 1 0.115
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.115
CDAN1 congenital dyserythropoietic anemia, type I 0.109
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.103
ZNF496 zinc finger protein 496 0.102
XIAP X-linked inhibitor of apoptosis 0.100
SYK spleen tyrosine kinase 0.099
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.099
NCOR2 nuclear receptor corepressor 2 0.099
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.099
SNX9 sorting nexin 9 0.096
AXIN1 axin 1 0.094
EXOC7 exocyst complex component 7 0.090
SNF8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.087
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.086
PRKCZ protein kinase C, zeta 0.086
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.085
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.082
ASF1B ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.080
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.079
SH3BP2 SH3-domain binding protein 2 0.077
PICALM phosphatidylinositol binding clathrin assembly protein 0.076
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.076
RBPMS RNA binding protein with multiple splicing 0.075
YY1 YY1 transcription factor 0.073
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.072
TEKT4 tektin 4 0.072
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.070
DLL1 delta-like 1 (Drosophila) 0.068
PTCH1 patched 1 0.067
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.066
PML promyelocytic leukemia 0.065
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.065
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.064
TCF4 transcription factor 4 0.064
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.062
CBX5 chromobox homolog 5 0.062
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Mus musculus
Name Description Probability Func Analog Organism
Psen1 presenilin 1 1.000
Notch1 Notch gene homolog 1 (Drosophila) 0.999
Shh sonic hedgehog 0.998
Vangl2 vang-like 2 (van gogh, Drosophila) 0.994
Hes1 hairy and enhancer of split 1 (Drosophila) 0.983
Eya1 eyes absent 1 homolog (Drosophila) 0.960
Sox2 SRY-box containing gene 2 0.960
Gli3 GLI-Kruppel family member GLI3 0.951
Tbx1 T-box 1 0.933
Dll1 delta-like 1 (Drosophila) 0.932
Ctnnb1 catenin (cadherin associated protein), beta 1 0.916
Rb1 retinoblastoma 1 0.898
Trp53 transformation related protein 53 0.897
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.890
Hoxb6 homeobox B6 0.886
Hand2 heart and neural crest derivatives expressed transcript 2 0.877
Efnb2 ephrin B2 0.872
Fgfr2 fibroblast growth factor receptor 2 0.861
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.841
Pax3 paired box gene 3 0.804
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.792
Foxc2 forkhead box C2 0.778
Nog noggin 0.755
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.732
Neurod1 neurogenic differentiation 1 0.729
Gsc goosecoid homeobox 0.724
Otx2 orthodenticle homolog 2 (Drosophila) 0.718
Ccnd1 cyclin D1 0.695
Msx1 homeobox, msh-like 1 0.683
Gata4 GATA binding protein 4 0.681
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.664
Dlx2 distal-less homeobox 2 0.661
Dll3 delta-like 3 (Drosophila) 0.643
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.631
Prrx1 paired related homeobox 1 0.628
Foxc1 forkhead box C1 0.620
Meox2 mesenchyme homeobox 2 0.616
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.588
Foxd3 forkhead box D3 0.575
She src homology 2 domain-containing transforming protein E 0.543
Hoxa13 homeobox A13 0.525
Foxa2 forkhead box A2 0.525
Hes5 hairy and enhancer of split 5 (Drosophila) 0.523
Nkx2-1 NK2 homeobox 1 0.512
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.483
Sox4 SRY-box containing gene 4 0.478
Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.470
Ptk7 PTK7 protein tyrosine kinase 7 0.469
App amyloid beta (A4) precursor protein 0.456
Sox18 SRY-box containing gene 18 0.435
Pten phosphatase and tensin homolog 0.424
Dlx5 distal-less homeobox 5 0.423
Hey1 hairy/enhancer-of-split related with YRPW motif 1 0.421
Edar ectodysplasin-A receptor 0.405
Isl1 ISL1 transcription factor, LIM/homeodomain 0.403
Notch3 Notch gene homolog 3 (Drosophila) 0.400
Hoxa11 homeobox A11 0.387
Pax6 paired box gene 6 0.367
Bmp7 bone morphogenetic protein 7 0.363
Pitx3 paired-like homeodomain transcription factor 3 0.352
Hoxa3 homeobox A3 0.351
Tcf21 transcription factor 21 0.350
Wnt3a wingless-related MMTV integration site 3A 0.345
Pax9 paired box gene 9 0.341
Ptch1 patched homolog 1 0.335
Chd7 chromodomain helicase DNA binding protein 7 0.335
Efna2 ephrin A2 0.334
Cyld cylindromatosis (turban tumor syndrome) 0.325
Snai1 snail homolog 1 (Drosophila) 0.322
Fgfr1 fibroblast growth factor receptor 1 0.318
Smad3 MAD homolog 3 (Drosophila) 0.317
Fgf15 fibroblast growth factor 15 0.314
Ptf1a pancreas specific transcription factor, 1a 0.306
Tbx15 T-box 15 0.303
Ebf3 early B-cell factor 3 0.300
Uncx UNC homeobox 0.300
Pitx2 paired-like homeodomain transcription factor 2 0.293
Dll4 delta-like 4 (Drosophila) 0.291
Pou3f3 POU domain, class 3, transcription factor 3 0.285
Foxg1 forkhead box G1 0.285
Pbx1 pre B-cell leukemia transcription factor 1 0.284
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.281
Hoxa2 homeobox A2 0.279
Mdm2 transformed mouse 3T3 cell double minute 2 0.277
Emx1 empty spiracles homolog 1 (Drosophila) 0.273
Padi3 peptidyl arginine deiminase, type III 0.271
Dlg1 discs, large homolog 1 (Drosophila) 0.265
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.263
Bbs2 Bardet-Biedl syndrome 2 (human) 0.261
Tbx2 T-box 2 0.257
Fzd7 frizzled homolog 7 (Drosophila) 0.249
Tcfap2a transcription factor AP-2, alpha 0.248
Hdac1 histone deacetylase 1 0.247
Kitl kit ligand 0.247
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.246
Alx4 aristaless-like homeobox 4 0.243
Tbx3 T-box 3 0.242
Tlx3 T-cell leukemia, homeobox 3 0.235
Smad6 MAD homolog 6 (Drosophila) 0.233
Etv4 ets variant gene 4 (E1A enhancer binding protein, E1AF) 0.229
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism