The network for 'regulation of macrophage chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of macrophage chemotaxis

Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
CCL4 chemokine (C-C motif) ligand 4 0.990
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.990
CXCL9 chemokine (C-X-C motif) ligand 9 0.986
APOE apolipoprotein E 0.986
CCL2 chemokine (C-C motif) ligand 2 0.983
CCL5 chemokine (C-C motif) ligand 5 0.959
CXCL10 chemokine (C-X-C motif) ligand 10 0.930
IL1B interleukin 1, beta 0.928
FYN FYN oncogene related to SRC, FGR, YES 0.925
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.865
FN1 fibronectin 1 0.849
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.814
IL8 interleukin 8 0.810
CCL8 chemokine (C-C motif) ligand 8 0.801
CXCL2 chemokine (C-X-C motif) ligand 2 0.782
LAT linker for activation of T cells 0.750
PDCD6IP programmed cell death 6 interacting protein 0.743
C1QB complement component 1, q subcomponent, B chain 0.733
CCR1 chemokine (C-C motif) receptor 1 0.723
IL10 interleukin 10 0.698
CXCL3 chemokine (C-X-C motif) ligand 3 0.651
CCL13 chemokine (C-C motif) ligand 13 0.629
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.602
CXCL11 chemokine (C-X-C motif) ligand 11 0.600
CTNND1 catenin (cadherin-associated protein), delta 1 0.542
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.536
DPP4 dipeptidyl-peptidase 4 0.511
RGS1 regulator of G-protein signaling 1 0.495
C2 complement component 2 0.481
C1QA complement component 1, q subcomponent, A chain 0.479
CD163 CD163 molecule 0.479
BCAR1 breast cancer anti-estrogen resistance 1 0.456
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.451
SLAMF8 SLAM family member 8 0.435
IL6 interleukin 6 (interferon, beta 2) 0.394
APOC1 apolipoprotein C-I 0.369
CCL3 chemokine (C-C motif) ligand 3 0.366
VSIG4 V-set and immunoglobulin domain containing 4 0.361
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.355
C5AR1 complement component 5a receptor 1 0.346
CXCL13 chemokine (C-X-C motif) ligand 13 0.342
TGFB1 transforming growth factor, beta 1 0.334
CFH complement factor H 0.331
PLEK pleckstrin 0.330
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.322
VCAM1 vascular cell adhesion molecule 1 0.318
MET met proto-oncogene (hepatocyte growth factor receptor) 0.302
CXCL5 chemokine (C-X-C motif) ligand 5 0.284
ADAMDEC1 ADAM-like, decysin 1 0.265
TNF tumor necrosis factor 0.258
CFI complement factor I 0.235
MATK megakaryocyte-associated tyrosine kinase 0.225
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.220
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.219
CCL22 chemokine (C-C motif) ligand 22 0.215
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.207
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.205
CCL7 chemokine (C-C motif) ligand 7 0.203
AQP9 aquaporin 9 0.196
IL7R interleukin 7 receptor 0.191
IFNG interferon, gamma 0.190
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.184
MSR1 macrophage scavenger receptor 1 0.183
ICAM1 intercellular adhesion molecule 1 0.173
MAPT microtubule-associated protein tau 0.170
C1S complement component 1, s subcomponent 0.170
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.164
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.154
CCR7 chemokine (C-C motif) receptor 7 0.150
CFB complement factor B 0.149
CD14 CD14 molecule 0.145
CCL19 chemokine (C-C motif) ligand 19 0.144
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.139
UBD ubiquitin D 0.136
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.134
CD83 CD83 molecule 0.126
MS4A4A membrane-spanning 4-domains, subfamily A, member 4 0.125
IL2RB interleukin 2 receptor, beta 0.122
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.122
CCL20 chemokine (C-C motif) ligand 20 0.116
SELE selectin E 0.115
HP haptoglobin 0.107
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.106
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.102
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.098
FPR3 formyl peptide receptor 3 0.095
ARHGAP32 Rho GTPase activating protein 32 0.093
CD2 CD2 molecule 0.092
C1QC complement component 1, q subcomponent, C chain 0.091
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.091
GAB1 GRB2-associated binding protein 1 0.090
CMKLR1 chemokine-like receptor 1 0.089
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.087
NNMT nicotinamide N-methyltransferase 0.083
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.082
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.081
IL18RAP interleukin 18 receptor accessory protein 0.080
CCL21 chemokine (C-C motif) ligand 21 0.079
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.079
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
mitfa microphthalmia-associated transcription factor a 0.699
cdh5 cadherin 5 0.526
etv2 ets variant gene 2 0.076
fli1a friend leukemia integration 1a 0.076
tie1 endothelium-specific receptor tyrosine kinase 1 0.066
tyr tyrosinase 0.066
sox7 SRY-box containing gene 7 0.057
kita kit receptor a 0.045
si:ch211-235f6.2 si:ch211-235f6.2 0.040
runx1 runt-related transcription factor 1 0.033
si:ch73-60e21.1 si:ch73-60e21.1 0.030
ednrb1 endothelin receptor B 0.028
dll4 delta-like 4 (Drosophila) 0.026
dct dopachrome tautomerase 0.026
cmyb transcription factor cmyb 0.025
tal1 T-cell acute lymphocytic leukemia 1 0.024
hbae1 hemoglobin alpha embryonic-1 0.021
tie2 endothelium-specific receptor tyrosine kinase 2 0.018
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.017
pnp4a purine nucleoside phosphorylase 4a 0.016
ltk leukocyte tyrosine kinase 0.015
bdnf brain-derived neurotrophic factor 0.014
cyp1a cytochrome P450, family 1, subfamily A 0.013
vegfaa vascular endothelial growth factor Aa 0.012
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.011
aox3 aldehyde oxidase 3 0.011
pax7b paired box gene 7b 0.011
gpr182 G protein-coupled receptor 182 0.011
slc45a2 solute carrier family 45, member 2 0.010
fabp11a fatty acid binding protein 11a 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Csf1 colony stimulating factor 1 (macrophage) 0.807
Ccr2 chemokine (C-C motif) receptor 2 0.779
Col1a1 collagen, type I, alpha 1 0.334
Msr1 macrophage scavenger receptor 1 0.259
Lox lysyl oxidase 0.206
Clec4d C-type lectin domain family 4, member d 0.203
Tlr4 toll-like receptor 4 0.192
Ccl3 chemokine (C-C motif) ligand 3 0.178
Il1rn interleukin 1 receptor antagonist 0.152
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.150
C3ar1 complement component 3a receptor 1 0.136
Ccr1 chemokine (C-C motif) receptor 1 0.129
Cd44 CD44 antigen 0.122
Mmp8 matrix metallopeptidase 8 0.120
Selp selectin, platelet 0.118
C5ar1 complement component 5a receptor 1 0.113
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.106
Ccl2 chemokine (C-C motif) ligand 2 0.106
Il1b interleukin 1 beta 0.103
Src Rous sarcoma oncogene 0.099
Il6 interleukin 6 0.095
Plau plasminogen activator, urokinase 0.091
Slfn4 schlafen 4 0.087
Fbn1 fibrillin 1 0.085
Cdh5 cadherin 5 0.074
Cxcl2 chemokine (C-X-C motif) ligand 2 0.071
Ccl4 chemokine (C-C motif) ligand 4 0.067
Ccl7 chemokine (C-C motif) ligand 7 0.062
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.061
Aoah acyloxyacyl hydrolase 0.055
Fpr1 formyl peptide receptor 1 0.051
Il1r1 interleukin 1 receptor, type I 0.044
Fcgr1 Fc receptor, IgG, high affinity I 0.042
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.042
Gab2 growth factor receptor bound protein 2-associated protein 2 0.041
Clec4e C-type lectin domain family 4, member e 0.041
Thbs2 thrombospondin 2 0.040
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.039
Saa3 serum amyloid A 3 0.038
Has1 hyaluronan synthase1 0.037
Fpr2 formyl peptide receptor 2 0.036
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.034
Chi3l3 chitinase 3-like 3 0.034
C1qtnf1 C1q and tumor necrosis factor related protein 1 0.033
Mmp9 matrix metallopeptidase 9 0.031
Aebp1 AE binding protein 1 0.030
Bcar1 breast cancer anti-estrogen resistance 1 0.029
Ptgir prostaglandin I receptor (IP) 0.029
Ccr5 chemokine (C-C motif) receptor 5 0.029
Irg1 immunoresponsive gene 1 0.029
Ush1g Usher syndrome 1G homolog (human) 0.028
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.028
Ch25h cholesterol 25-hydroxylase 0.028
Loxl1 lysyl oxidase-like 1 0.027
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.027
Thbs1 thrombospondin 1 0.027
Nos2 nitric oxide synthase 2, inducible 0.024
Mmp12 matrix metallopeptidase 12 0.024
Ush1c Usher syndrome 1C homolog (human) 0.023
Il1a interleukin 1 alpha 0.023
Itgax integrin alpha X 0.022
Plaur plasminogen activator, urokinase receptor 0.022
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.022
Mmp3 matrix metallopeptidase 3 0.022
Mfap5 microfibrillar associated protein 5 0.022
Slfn1 schlafen 1 0.022
Osmr oncostatin M receptor 0.021
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.021
Ctsk cathepsin K 0.019
Dab2 disabled homolog 2 (Drosophila) 0.019
Slpi secretory leukocyte peptidase inhibitor 0.017
Ccl8 chemokine (C-C motif) ligand 8 0.017
Klra2 killer cell lectin-like receptor, subfamily A, member 2 0.017
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.017
Smad3 MAD homolog 3 (Drosophila) 0.017
Srpx sushi-repeat-containing protein 0.017
Cx3cr1 chemokine (C-X3-C) receptor 1 0.017
Dok1 docking protein 1 0.016
Icam1 intercellular adhesion molecule 1 0.016
Cxcl1 chemokine (C-X-C motif) ligand 1 0.016
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.015
Ccl12 chemokine (C-C motif) ligand 12 0.015
Col6a1 collagen, type VI, alpha 1 0.015
Ccl9 chemokine (C-C motif) ligand 9 0.015
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.015
Gfpt2 glutamine fructose-6-phosphate transaminase 2 0.015
Mrc2 mannose receptor, C type 2 0.015
Ngp neutrophilic granule protein 0.014
Timp1 tissue inhibitor of metalloproteinase 1 0.014
Ptgs2 prostaglandin-endoperoxide synthase 2 0.014
Ifitm6 interferon induced transmembrane protein 6 0.014
Cybb cytochrome b-245, beta polypeptide 0.014
Il18rap interleukin 18 receptor accessory protein 0.013
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.013
Adam8 a disintegrin and metallopeptidase domain 8 0.013
Htra3 HtrA serine peptidase 3 0.013
Plat plasminogen activator, tissue 0.012
Il10 interleukin 10 0.012
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.012
Itgam integrin alpha M 0.012
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cd14 CD14 molecule 0.169
C1qc complement component 1, q subcomponent, C chain 0.118
Cxcl10 chemokine (C-X-C motif) ligand 10 0.062
Gzmb granzyme B 0.043
Il1b interleukin 1 beta 0.040
Cd68 Cd68 molecule 0.031
Tlr7 toll-like receptor 7 0.031
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.031
PVR poliovirus receptor 0.030
Hmox1 heme oxygenase (decycling) 1 0.026
Igsf6 immunoglobulin superfamily, member 6 0.026
Clec4a3 C-type lectin domain family 4, member a3 0.025
Laptm5 lysosomal protein transmembrane 5 0.022
Tcrb T-cell receptor beta chain 0.022
Prf1 perforin 1 (pore forming protein) 0.021
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.019
Cd37 CD37 molecule 0.019
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.019
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.018
Nkg7 natural killer cell group 7 sequence 0.018
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.017
Tyrobp Tyro protein tyrosine kinase binding protein 0.016
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.016
Cybb cytochrome b-245, beta polypeptide 0.016
Ier3 immediate early response 3 0.014
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.014
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.014
Pld4 phospholipase D family, member 4 0.014
Il2rb interleukin 2 receptor, beta 0.014
Hck hemopoietic cell kinase 0.013
Epn1 Epsin 1 0.013
Stat6 signal transducer and activator of transcription 6 0.013
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.012
Ptgs2 prostaglandin-endoperoxide synthase 2 0.012
Icam1 intercellular adhesion molecule 1 0.012
Il2rg interleukin 2 receptor, gamma 0.012
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.011
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.011
Igh-6 immunoglobulin heavy chain 6 0.011
Dmbt1 deleted in malignant brain tumors 1 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism