The network for 'regulation of hematopoietic progenitor cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of hematopoietic progenitor cell differentiation

Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.

Homo sapiens
Name Description Probability Func Analog Organism
HIST1H2BH histone cluster 1, H2bh 0.999
HIST1H2BC histone cluster 1, H2bc 0.997
HIST1H2BG histone cluster 1, H2bg 0.986
HIST1H3D histone cluster 1, H3d 0.985
HIST1H2AE histone cluster 1, H2ae 0.941
HIST1H1C histone cluster 1, H1c 0.927
HIST1H2AJ histone cluster 1, H2aj 0.918
HIST1H2BD histone cluster 1, H2bd 0.889
HIST2H2BE histone cluster 2, H2be 0.851
HIST1H3H histone cluster 1, H3h 0.847
HDAC3 histone deacetylase 3 0.786
HIST1H2AM histone cluster 1, H2am 0.759
HIST1H4D histone cluster 1, H4d 0.720
HIST1H4B histone cluster 1, H4b 0.681
HIST1H2AI histone cluster 1, H2ai 0.655
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.651
HIST1H2AL histone cluster 1, H2al 0.626
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.612
HIST1H2BI histone cluster 1, H2bi 0.567
HIST1H3B histone cluster 1, H3b 0.543
CXCL2 chemokine (C-X-C motif) ligand 2 0.504
HIST1H2BF histone cluster 1, H2bf 0.502
HIST1H4A histone cluster 1, H4a 0.473
IL8 interleukin 8 0.461
HIST1H2BJ histone cluster 1, H2bj 0.459
HIST1H1E histone cluster 1, H1e 0.429
CXCL3 chemokine (C-X-C motif) ligand 3 0.426
HIST1H2AB histone cluster 1, H2ab 0.397
NRP1 neuropilin 1 0.391
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.370
HIST1H2BE histone cluster 1, H2be 0.363
HIST1H4F histone cluster 1, H4f 0.348
HIST1H4H histone cluster 1, H4h 0.318
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.299
HIST1H2BM histone cluster 1, H2bm 0.281
PSEN2 presenilin 2 (Alzheimer disease 4) 0.269
HIST1H3A histone cluster 1, H3a 0.246
HIST1H4E histone cluster 1, H4e 0.223
PGF placental growth factor 0.209
HIST1H4C histone cluster 1, H4c 0.209
HMGB2 high mobility group box 2 0.199
SP3 Sp3 transcription factor 0.193
CXCL5 chemokine (C-X-C motif) ligand 5 0.190
TAL1 T-cell acute lymphocytic leukemia 1 0.187
JAG1 jagged 1 0.167
WASL Wiskott-Aldrich syndrome-like 0.167
HIST1H3G histone cluster 1, H3g 0.162
PTMA prothymosin, alpha 0.162
HIST2H2AA4 histone cluster 2, H2aa4 0.161
CXCL11 chemokine (C-X-C motif) ligand 11 0.152
HIST1H2BB histone cluster 1, H2bb 0.149
HIST1H2AK histone cluster 1, H2ak 0.147
HIST1H2BK histone cluster 1, H2bk 0.145
HMG20A high mobility group 20A 0.141
DPP4 dipeptidyl-peptidase 4 0.140
HIST2H4A histone cluster 2, H4a 0.118
HIST1H4J histone cluster 1, H4j 0.118
CCL20 chemokine (C-C motif) ligand 20 0.113
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.110
HIST1H4I histone cluster 1, H4i 0.109
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.102
PTPRB protein tyrosine phosphatase, receptor type, B 0.097
HIST2H2AC histone cluster 2, H2ac 0.097
HIST1H2BO histone cluster 1, H2bo 0.092
HMGB1 high mobility group box 1 0.091
HIST2H4B histone cluster 2, H4b 0.089
ARFIP2 ADP-ribosylation factor interacting protein 2 0.089
HIST1H4L histone cluster 1, H4l 0.085
VEGFA vascular endothelial growth factor A 0.084
HMGA1 high mobility group AT-hook 1 0.082
HIST1H2BN histone cluster 1, H2bn 0.075
HIST1H2AC histone cluster 1, H2ac 0.070
CXCL10 chemokine (C-X-C motif) ligand 10 0.070
HIST2H2AA3 histone cluster 2, H2aa3 0.069
SP1 Sp1 transcription factor 0.061
NOTCH3 notch 3 0.060
HIST1H2AG histone cluster 1, H2ag 0.058
CDH5 cadherin 5, type 2 (vascular endothelium) 0.054
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.051
TP53BP1 tumor protein p53 binding protein 1 0.050
PF4 platelet factor 4 0.045
PHF10 PHD finger protein 10 0.041
HIST3H3 histone cluster 3, H3 0.040
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.040
HMGN2 high mobility group nucleosomal binding domain 2 0.039
IL6 interleukin 6 (interferon, beta 2) 0.036
HIST1H3F histone cluster 1, H3f 0.036
HIST1H3C histone cluster 1, H3c 0.032
HIST1H3I histone cluster 1, H3i 0.031
EFNA1 ephrin-A1 0.031
CYTH2 cytohesin 2 0.029
PLCG1 phospholipase C, gamma 1 0.028
OFCC1 orofacial cleft 1 candidate 1 0.028
CCL8 chemokine (C-C motif) ligand 8 0.027
LAT linker for activation of T cells 0.027
MAML1 mastermind-like 1 (Drosophila) 0.025
HIST1H2BL histone cluster 1, H2bl 0.024
HIST1H2AH histone cluster 1, H2ah 0.024
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.024
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.023
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
wt1b wilms tumor 1b 0.550
etv2 ets variant gene 2 0.403
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.295
her12 hairy-related 12 0.272
tmem88a transmembrane protein 88 a 0.268
pkd2 polycystic kidney disease 2 0.250
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.186
her15.1 hairy and enhancer of split-related 15.1 0.156
mecom MDS1 and EVI1 complex locus 0.149
vegfaa vascular endothelial growth factor Aa 0.145
foxn4 forkhead box N4 0.140
si:ch73-60e21.1 si:ch73-60e21.1 0.136
notch3 notch homolog 3 0.124
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.123
tal1 T-cell acute lymphocytic leukemia 1 0.122
myl7 myosin, light polypeptide 7, regulatory 0.121
tie2 endothelium-specific receptor tyrosine kinase 2 0.121
hmgb2a high-mobility group box 2a 0.120
dla deltaA 0.107
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.106
hmgb1b high-mobility group box 1b 0.098
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.086
olig4 oligodendrocyte transcription factor 4 0.086
aplnrb apelin receptor b 0.083
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.080
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.073
dll4 delta-like 4 (Drosophila) 0.068
hmgb3a high-mobility group box 3a 0.068
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.068
h2afvl H2A histone family, member V, like 0.064
tbx16 T-box gene 16 0.064
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.060
arl4ab ADP-ribosylation factor-like 4ab 0.059
esama endothelial cell adhesion molecule a 0.051
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.051
crb2a crumbs homolog 2a 0.051
sox3 SRY-box containing gene 3 0.049
epas1b endothelial PAS domain protein 1b 0.046
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.046
ascl1a achaete-scute complex-like 1a (Drosophila) 0.045
hmga1a high mobility group AT-hook 1a 0.042
casp8 caspase 8, apoptosis-related cysteine peptidase 0.042
insm1a insulinoma-associated 1a 0.041
osr1 odd-skipped related 1 (Drosophila) 0.041
podxl podocalyxin-like 0.041
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.039
tbx5a T-box 5a 0.039
hmgb2b high-mobility group box 2b 0.039
rad21 RAD21 homolog (S. pombe) 0.038
si:ch211-235f6.2 si:ch211-235f6.2 0.038
sesn1 sestrin 1 0.037
zgc:56136 zgc:56136 0.037
cftr cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) 0.037
psmb9a proteasome (prosome, macropain) subunit, beta type, 9a 0.037
dusp5 dual specificity phosphatase 5 0.035
tlr22 toll-like receptor 22 0.035
her6 hairy-related 6 0.035
wtip Wilms tumor 1 interacting protein 0.034
ubin ataxin-1 ubiquitin-like interacting protein 0.033
dlb deltaB 0.033
plxnd1 plexin D1 0.033
dnmt3 DNA (cytosine-5-)-methyltransferase 3 0.032
sox19a SRY-box containing gene 19a 0.032
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.032
gata1a GATA binding protein 1a 0.030
lama1 laminin, alpha 1 0.029
mef2cb myocyte enhancer factor 2cb 0.029
sox7 SRY-box containing gene 7 0.029
flot1 flotillin 1 0.029
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.029
rab11a RAB11a, member RAS oncogene family 0.028
plaua plasminogen activator, urokinase a 0.028
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.028
eomesa eomesodermin homolog a 0.028
msi1 musashi homolog 1 (Drosophila) 0.028
ptpreb protein tyrosine phosphatase, receptor type, E, b 0.027
ptpn21 protein tyrosine phosphatase, non-receptor type 21 0.027
ttna titin a 0.027
tagln transgelin 0.026
lmo2 LIM domain only 2 (rhombotin-like 1) 0.026
zgc:101614 zgc:101614 0.026
elmo1 engulfment and cell motility 1 (ced-12 homolog, C. elegans) 0.026
itgav integrin, alpha V 0.025
clec14a C-type lectin domain family 14, member A 0.025
rbm24a RNA binding motif protein 24a 0.025
dmrta2 doublesex and mab-3 related transcription factor like family A2 0.025
gper G protein-coupled estrogen receptor 1 0.025
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.025
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.025
LOC566708 FL cytokine receptor-like 0.024
otpb orthopedia homolog b 0.024
cmlc1 cardiac myosin light chain-1 0.024
h3f3a H3 histone, family 3A 0.024
bmp10 bone morphogenetic protein 10 0.024
adora2b adenosine A2b receptor 0.024
defbl3 defensin, beta-like 3 0.023
nf1b neurofibromin 1b 0.023
stat1b signal transducer and activator of transcription 1b 0.023
lhx5 LIM homeobox 5 0.023
mmp17a matrix metallopeptidase 17a 0.023
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Drosophila melanogaster
Name Description Probability Func Analog Organism
HLHmdelta E(spl) region transcript mdelta 0.983
HLHm7 E(spl) region transcript m7 0.971
E(spl) Enhancer of split 0.913
malpha E(spl) region transcript malpha 0.578
HLHm5 E(spl) region transcript m5 0.443
HLHmgamma E(spl) region transcript mgamma 0.434
Tom Twin of m4 0.394
HLHmbeta E(spl) region transcript mbeta 0.338
m2 E(spl) region transcript m2 0.258
ac achaete 0.235
m4 E(spl) region transcript m4 0.164
HLHm3 E(spl) region transcript m3 0.139
sc scute 0.102
ed echinoid 0.054
BobA Brother of Bearded A 0.052
kuz kuzbanian 0.050
emc extra macrochaetae 0.045
gro groucho 0.044
bib big brain 0.035
HIP-R Hsc/Hsp70-interacting protein related 0.033
mbc myoblast city 0.029
ase asense 0.026
Abi Abelson interacting protein 0.025
comm commissureless 0.025
H Hairless 0.023
Su(H) Suppressor of Hairless 0.020
SoxN SoxNeuro 0.020
Notum CG13076 gene product from transcript CG13076-RB 0.020
noc no ocelli 0.019
htl heartless 0.019
tap target of Poxn 0.018
scb scab 0.018
ush u-shaped 0.017
brat brain tumor 0.017
aop anterior open 0.017
mam mastermind 0.016
CG4968 CG4968 gene product from transcript CG4968-RA 0.015
ato atonal 0.015
smt3 CG4494 gene product from transcript CG4494-RA 0.015
en engrailed 0.013
Myd88 CG2078 gene product from transcript CG2078-RA 0.012
m6 E(spl) region transcript m6 0.012
loj logjam 0.012
phyl phyllopod 0.012
Pvr PDGF- and VEGF-receptor related 0.012
JIL-1 CG6297 gene product from transcript CG6297-RA 0.012
kst karst 0.012
da daughterless 0.011
stg string 0.011
klu klumpfuss 0.011
brm brahma 0.011
Usp7 ubiquitin-specific protease 7 0.010
Gsc Goosecoid 0.010
eg eagle 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Nos3 nitric oxide synthase 3, endothelial cell 0.866
Vegfa vascular endothelial growth factor A 0.821
Kdr kinase insert domain protein receptor 0.784
Flt4 FMS-like tyrosine kinase 4 0.714
Dll1 delta-like 1 (Drosophila) 0.691
Gfi1b growth factor independent 1B 0.599
Psen1 presenilin 1 0.500
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.473
Tgfb2 transforming growth factor, beta 2 0.455
Jag1 jagged 1 0.433
Efnb2 ephrin B2 0.319
Gata4 GATA binding protein 4 0.271
Hes1 hairy and enhancer of split 1 (Drosophila) 0.240
Sox2 SRY-box containing gene 2 0.233
Meox2 mesenchyme homeobox 2 0.232
Pitx2 paired-like homeodomain transcription factor 2 0.224
Foxc2 forkhead box C2 0.222
Rxra retinoid X receptor alpha 0.215
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.189
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.189
Emx1 empty spiracles homolog 1 (Drosophila) 0.172
Egfr epidermal growth factor receptor 0.161
Ctnnb1 catenin (cadherin associated protein), beta 1 0.161
Klf3 Kruppel-like factor 3 (basic) 0.155
Setdb1 SET domain, bifurcated 1 0.148
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.142
Gata6 GATA binding protein 6 0.135
Egfl7 EGF-like domain 7 0.128
Bmp4 bone morphogenetic protein 4 0.124
Cbl Casitas B-lineage lymphoma 0.123
Rb1 retinoblastoma 1 0.122
Ikzf1 IKAROS family zinc finger 1 0.117
Shh sonic hedgehog 0.116
Fbxo11 F-box protein 11 0.113
Adam17 a disintegrin and metallopeptidase domain 17 0.108
Tgfbr2 transforming growth factor, beta receptor II 0.108
Grb2 growth factor receptor bound protein 2 0.107
Notch1 Notch gene homolog 1 (Drosophila) 0.105
Tal1 T-cell acute lymphocytic leukemia 1 0.105
Hdac5 histone deacetylase 5 0.105
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.103
Runx1 runt related transcription factor 1 0.101
Fgf8 fibroblast growth factor 8 0.093
Chd7 chromodomain helicase DNA binding protein 7 0.089
Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 0.081
Pdgfb platelet derived growth factor, B polypeptide 0.078
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.075
Csf1 colony stimulating factor 1 (macrophage) 0.072
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.070
Apaf1 apoptotic peptidase activating factor 1 0.069
Gaa glucosidase, alpha, acid 0.067
Foxg1 forkhead box G1 0.066
Gab2 growth factor receptor bound protein 2-associated protein 2 0.065
Pou5f1 POU domain, class 5, transcription factor 1 0.065
Fgfr2 fibroblast growth factor receptor 2 0.064
She src homology 2 domain-containing transforming protein E 0.063
Foxc1 forkhead box C1 0.061
Elk3 ELK3, member of ETS oncogene family 0.061
Qk quaking 0.060
Fzd4 frizzled homolog 4 (Drosophila) 0.060
Sox7 SRY-box containing gene 7 0.059
Pten phosphatase and tensin homolog 0.058
Smad7 MAD homolog 7 (Drosophila) 0.057
Fnip1 folliculin interacting protein 1 0.057
Gja1 gap junction protein, alpha 1 0.048
Smad6 MAD homolog 6 (Drosophila) 0.047
Hdac4 histone deacetylase 4 0.047
Wdr26 WD repeat domain 26 0.047
Psen2 presenilin 2 0.045
Vegfc vascular endothelial growth factor C 0.044
Smad3 MAD homolog 3 (Drosophila) 0.044
Acvr1 activin A receptor, type 1 0.042
Ncoa6 nuclear receptor coactivator 6 0.042
Kit kit oncogene 0.042
Shc1 src homology 2 domain-containing transforming protein C1 0.041
Cdh5 cadherin 5 0.040
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.040
Zfpm2 zinc finger protein, multitype 2 0.040
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.040
Espn espin 0.039
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.039
Kdm2b lysine (K)-specific demethylase 2B 0.038
Notch2 Notch gene homolog 2 (Drosophila) 0.038
Sp3 trans-acting transcription factor 3 0.036
Lrrc58 leucine rich repeat containing 58 0.035
Tek endothelial-specific receptor tyrosine kinase 0.033
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.031
Tbx3 T-box 3 0.031
Gli3 GLI-Kruppel family member GLI3 0.031
Sox17 SRY-box containing gene 17 0.030
Emx2 empty spiracles homolog 2 (Drosophila) 0.030
Ldb2 LIM domain binding 2 0.030
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.030
Epor erythropoietin receptor 0.029
Abi1 abl-interactor 1 0.029
Ets1 E26 avian leukemia oncogene 1, 5' domain 0.028
Tbx2 T-box 2 0.028
Ptprb protein tyrosine phosphatase, receptor type, B 0.028
Plcg1 phospholipase C, gamma 1 0.028
Apc adenomatosis polyposis coli 0.028
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ndufb10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10 0.015
LOC100362298 ribosomal protein S18-like 0.015
Rps26 ribosomal protein S26 0.014
Rpl38 ribosomal protein L38 0.014
Ndufa2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 0.013
Mrps21 mitochondrial ribosomal protein S21 0.011
Rpl27 ribosomal protein L27 0.011
LOC100361944 hypothetical protein LOC100361944 0.011
Rpl9 ribosomal protein L9 0.011
LOC100362751 ribosomal protein P2-like 0.011
Atp5o ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.010
Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 0.010
Myeov2 myeloma overexpressed 2 0.010
Ndufb5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism