The network for 'cellular pigmentation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular pigmentation

The deposition or aggregation of coloring matter in a cell.

Mus musculus
Name Description Probability Func Analog Organism
Lyst lysosomal trafficking regulator 0.997
a nonagouti 0.995
Pldn pallidin 0.975
Rab27a RAB27A, member RAS oncogene family 0.966
Hps1 Hermansky-Pudlak syndrome 1 homolog (human) 0.960
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.953
Mitf microphthalmia-associated transcription factor 0.898
Ap3b1 adaptor-related protein complex 3, beta 1 subunit 0.873
Tyr tyrosinase 0.847
Bbs4 Bardet-Biedl syndrome 4 (human) 0.775
Oca2 oculocutaneous albinism II 0.719
Tyrp1 tyrosinase-related protein 1 0.681
Bbs1 Bardet-Biedl syndrome 1 (human) 0.665
Hps5 Hermansky-Pudlak syndrome 5 homolog (human) 0.583
Muted muted 0.479
Bbs2 Bardet-Biedl syndrome 2 (human) 0.474
Mlph melanophilin 0.458
Hps6 Hermansky-Pudlak syndrome 6 0.335
Ap2m1 adaptor protein complex AP-2, mu1 0.264
Slc24a5 solute carrier family 24, member 5 0.233
Atp6v0b ATPase, H+ transporting, lysosomal V0 subunit B 0.222
Kit kit oncogene 0.189
Pmel premelanosome protein 0.161
Ap3d1 adaptor-related protein complex 3, delta 1 subunit 0.154
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.151
Bax BCL2-associated X protein 0.147
Pi4kb phosphatidylinositol 4-kinase, catalytic, beta polypeptide 0.128
Vapa vesicle-associated membrane protein, associated protein A 0.127
Mc1r melanocortin 1 receptor 0.123
Hps4 Hermansky-Pudlak syndrome 4 homolog (human) 0.101
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.090
Myo5a myosin VA 0.087
Stx7 syntaxin 7 0.087
Ap1g1 adaptor protein complex AP-1, gamma 1 subunit 0.079
Cno cappuccino 0.075
Ap1m1 adaptor-related protein complex AP-1, mu subunit 1 0.070
Rab38 RAB38, member of RAS oncogene family 0.068
Ush1g Usher syndrome 1G homolog (human) 0.068
Cdh23 cadherin 23 (otocadherin) 0.066
Bcl2 B-cell leukemia/lymphoma 2 0.059
Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 0.059
Slc45a2 solute carrier family 45, member 2 0.056
Stx12 syntaxin 12 0.053
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.052
Hps3 Hermansky-Pudlak syndrome 3 homolog (human) 0.051
Dctn2 dynactin 2 0.050
Tmem30a transmembrane protein 30A 0.049
Psap prosaposin 0.046
Kitl kit ligand 0.045
Rab11a RAB11a, member RAS oncogene family 0.043
Csnk1g2 casein kinase 1, gamma 2 0.042
Pld3 phospholipase D family, member 3 0.038
Thrb thyroid hormone receptor beta 0.035
Pax6 paired box gene 6 0.035
Crb3 crumbs homolog 3 (Drosophila) 0.033
Chmp5 chromatin modifying protein 5 0.032
Trpm1 transient receptor potential cation channel, subfamily M, member 1 0.031
Bbs5 Bardet-Biedl syndrome 5 (human) 0.030
Bak1 BCL2-antagonist/killer 1 0.027
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.026
LOC100503041 PDZ domain-containing protein 7-like 0.025
Chmp1a chromatin modifying protein 1A 0.025
Myo15 myosin XV 0.024
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.023
Ttc8 tetratricopeptide repeat domain 8 0.022
Trp53 transformation related protein 53 0.022
Rragc Ras-related GTP binding C 0.022
Anapc2 anaphase promoting complex subunit 2 0.022
Cltc clathrin, heavy polypeptide (Hc) 0.022
Shh sonic hedgehog 0.022
Atp6v1c1 ATPase, H+ transporting, lysosomal V1 subunit C1 0.022
Ush1c Usher syndrome 1C homolog (human) 0.021
Dbnl drebrin-like 0.021
Bbs7 Bardet-Biedl syndrome 7 (human) 0.020
Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C 0.020
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.019
Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.019
Bag6 BCL2-associated athanogene 6 0.019
Clptm1 cleft lip and palate associated transmembrane protein 1 0.019
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.019
Dtnbp1 dystrobrevin binding protein 1 0.019
Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 0.018
Gpr98 G protein-coupled receptor 98 0.018
Nptn neuroplastin 0.018
Gns glucosamine (N-acetyl)-6-sulfatase 0.017
Mfn2 mitofusin 2 0.017
Tmub2 transmembrane and ubiquitin-like domain containing 2 0.017
Grxcr1 glutaredoxin, cysteine rich 1 0.017
Espn espin 0.016
Bbs9 Bardet-Biedl syndrome 9 (human) 0.016
Npy1r neuropeptide Y receptor Y1 0.016
Wsb2 WD repeat and SOCS box-containing 2 0.016
Napa N-ethylmaleimide sensitive fusion protein attachment protein alpha 0.016
Pomc pro-opiomelanocortin-alpha 0.016
Wbp2 WW domain binding protein 2 0.015
Rheb Ras homolog enriched in brain 0.015
Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.015
Tmem9b TMEM9 domain family, member B 0.015
Sh3glb2 SH3-domain GRB2-like endophilin B2 0.015
Sptlc2 serine palmitoyltransferase, long chain base subunit 2 0.014
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
sc:d812 sc:d812 0.863
pmela premelanosome protein a 0.856
kif17 kinesin family member 17 0.785
mlphb melanophilin b 0.763
atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.738
ift80 intraflagellar transport 80 homolog (Chlamydomonas) 0.733
cc2d2a coiled-coil and C2 domain containing 2A 0.732
tyrp1 tyrosinase-related protein 1 0.713
ift88 intraflagellar transport 88 homolog 0.703
kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 0.682
foxp2 forkhead box P2 0.676
cx41.8 connexin 41.8 0.659
dct dopachrome tautomerase 0.584
barhl1.2 BarH-like 1.2 0.582
barhl2 BarH-like 2 0.565
prl prolactin 0.521
pou1f1 POU domain, class 1, transcription factor 1 0.514
mitfb microphthalmia-associated transcription factor b 0.501
ift57 intraflagellar transport protein 57 0.501
atp6v1e1b ATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b 0.500
hmx2 H6 family homeobox 2 0.420
ttc26 tetratricopeptide repeat domain 26 0.411
mitfa microphthalmia-associated transcription factor a 0.408
zgc:100919 zgc:100919 0.406
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.387
tfap2e transcription factor AP-2 epsilon 0.364
sncb synuclein, beta 0.341
bdnf brain-derived neurotrophic factor 0.339
tshb thyroid stimulating hormone, beta subunit 0.325
tyrp1b tyrosinase-related protein 1b 0.266
pdzd7a PDZ domain containing 7a 0.253
bbs2 Bardet-Biedl syndrome 2 0.244
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.235
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.232
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.215
irx4b iroquois homeobox protein 4b 0.206
tctex1d2 Tctex1 domain containing 2 0.185
zgc:112329 zgc:112329 0.160
ift52 intraflagellar transport protein 52 0.158
tmem199 transmembrane protein 199 0.153
otpb orthopedia homolog b 0.145
atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 0.139
nphs2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.136
dync1h1 dynein, cytoplasmic 1, heavy chain 1 0.132
spra sepiapterin reductase a 0.127
pomca proopiomelanocortin a 0.112
chga chromogranin A 0.110
si:ch211-150c22.3 si:ch211-150c22.3 0.102
arl6 ADP-ribosylation factor-like 6 0.100
slc24a5 solute carrier family 24, member 5 0.099
mks1 meckel syndrome, type 1 0.097
si:dkey-222f8.3 si:dkey-222f8.3 0.093
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.090
ift172 intraflagellar transport 172 0.089
cluap1 clusterin associated protein 1 0.088
atp6v0d1 ATPase, H+ transporting, V0 subunit D isoform 1 0.087
tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) 0.085
commd3 COMM domain containing 3 0.085
cdh6 cadherin 6 0.081
syne2a spectrin repeat containing, nuclear envelope 2a 0.078
sypl2b synaptophysin-like 2b 0.075
scamp2 secretory carrier membrane protein 2 0.075
adcyap1r1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.073
ctbp2 C-terminal binding protein 2 0.071
otx2 orthodenticle homolog 2 0.071
cdh10 cadherin 10, type 2 (T2-cadherin) 0.070
zgc:100994 zgc:100994 0.069
snx5 sorting nexin 5 0.059
hcrt hypocretin (orexin) neuropeptide precursor 0.058
tyr tyrosinase 0.055
arpc5a actin related protein 2/3 complex, subunit 5A 0.054
smtla somatolactin alpha 0.053
ropn1l ropporin 1-like 0.053
atp6v1f ATPase, H+ transporting, V1 subunit F 0.052
adm2 adrenomedullin 2 0.051
slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.050
bbs4 Bardet-Biedl syndrome 4 0.050
uap1l1 UDP-N-acteylglucosamine pyrophosphorylase 1, like 1 0.050
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.049
bbs7 Bardet-Biedl syndrome 7 0.049
ctsd cathepsin D 0.049
slc41a1 solute carrier family 41, member 1 0.048
wnt7aa wingless-type MMTV integration site family, member 7Aa 0.048
snx12 sorting nexin 12 0.048
cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.046
csf1ra colony stimulating factor 1 receptor, a 0.046
ap1s1 adaptor-related protein complex 1, sigma 1 subunit 0.045
mst1rb macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b 0.045
styk1 serine/threonine/tyrosine kinase 1 0.045
tsga14 testis specific, 14 0.044
adcyap1b adenylate cyclase activating polypeptide 1b 0.044
pfn2 profilin 2 0.044
si:dkey-174n20.1 si:dkey-174n20.1 0.043
crabp1a cellular retinoic acid binding protein 1a 0.042
otpa orthopedia homolog a 0.042
flot1 flotillin 1 0.041
arl3 ADP-ribosylation factor-like 3 0.041
rras related RAS viral (r-ras) oncogene homolog 0.040
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.040
cbx1b chromobox homolog 1b (HP1 beta homolog Drosophila) 0.040
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Drosophila melanogaster
Name Description Probability Func Analog Organism
rb ruby 0.805
CdsA CDP diglyceride synthetase 0.720
lt light 0.637
osp outspread 0.355
sina seven in absentia 0.274
or orange 0.246
dysb dysbindin 0.224
rl rolled 0.183
Vps16A Vacuolar protein sorting 16A 0.148
B-H1 BarH1 0.119
bw brown 0.112
Galpha49B G protein alpha49B 0.094
msl-1 male-specific lethal 1 0.078
CG11347 CG11347 gene product from transcript CG11347-RE 0.074
frtz fritz 0.070
CG6116 CG6116 gene product from transcript CG6116-RA 0.065
cn cinnabar 0.065
Rab7 Rab-protein 7 0.059
CG14408 CG14408 gene product from transcript CG14408-RA 0.059
sns sticks and stones 0.056
kirre kin of irre 0.050
CG9418 CG9418 gene product from transcript CG9418-RA 0.047
AP-47 CG9388 gene product from transcript CG9388-RA 0.046
wb wing blister 0.046
ro rough 0.046
eyg eyegone 0.044
Vha68-2 CG3762 gene product from transcript CG3762-RA 0.038
Atg8a Autophagy-specific gene 8a 0.037
eff effete 0.036
drd drop dead 0.035
Vps16B Vacuolar protein sorting 16B 0.034
Stam Signal transducing adaptor molecule 0.034
rt rotated abdomen 0.032
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.031
beta4GalNAcTA CG8536 gene product from transcript CG8536-RA 0.030
car carnation 0.030
mld molting defective 0.029
nau nautilus 0.029
C15 CG7937 gene product from transcript CG7937-RA 0.025
kar karmoisin 0.025
nonA no on or off transient A 0.025
sing singles bar 0.024
Hand CG18144 gene product from transcript CG18144-RA 0.023
sn singed 0.023
sw short wing 0.023
Chc Clathrin heavy chain 0.022
sip1 septin interacting protein 1 0.021
hbs hibris 0.020
Gga CG3002 gene product from transcript CG3002-RB 0.020
Cdk5alpha Cdk5 activator-like protein 0.020
Ilk Integrin linked kinase 0.020
klg klingon 0.020
Nipped-B CG17704 gene product from transcript CG17704-RI 0.020
amos absent MD neurons and olfactory sensilla 0.019
pallidin CG14133 gene product from transcript CG14133-RB 0.019
Hip14 Huntingtin-interacting protein 14 0.019
Npc1a Niemann-Pick type C-1a 0.019
Spt-I Serine palmitoyltransferase subunit I 0.019
Klp64D Kinesin-like protein at 64D 0.018
CG34404 CG34404 gene product from transcript CG34404-RD 0.018
S6kII RPS6-protein kinase-II 0.018
Dlic Dynein light intermediate chain 0.017
Tre1 trapped in endoderm-1 0.017
CG15309 CG15309 gene product from transcript CG15309-RA 0.017
Mocs1 CG33048 gene product from transcript CG33048-RA 0.017
CG30428 CG30428 gene product from transcript CG30428-RA 0.016
CG6490 CG6490 gene product from transcript CG6490-RB 0.016
Ef1alpha48D Elongation factor 1alpha48D 0.016
CG9186 CG9186 gene product from transcript CG9186-RB 0.015
sm smooth 0.015
CG40127 CG40127 gene product from transcript CG40127-RA 0.015
pn prune 0.014
ninaB neither inactivation nor afterpotential B 0.014
Nak Numb-associated kinase 0.014
Vha26 Vacuolar H[+]-ATPase 26kD E subunit 0.014
VhaM9.7-2 CG7625 gene product from transcript CG7625-RA 0.014
CG13287 CG13287 gene product from transcript CG13287-RA 0.013
VhaM9.7-1 CG11589 gene product from transcript CG11589-RA 0.013
l(3)82Fd CG32464 gene product from transcript CG32464-RR 0.013
Vps26 Vacuolar protein sorting 26 0.013
CG31919 CG31919 gene product from transcript CG31919-RC 0.013
CG10681 CG10681 gene product from transcript CG10681-RA 0.013
CG7536 CG7536 gene product from transcript CG7536-RB 0.013
deltaCOP delta-coatomer protein 0.013
yata CG1973 gene product from transcript CG1973-RA 0.013
ltd lightoid 0.012
CG17265 CG17265 gene product from transcript CG17265-RA 0.012
cutlet CG33122 gene product from transcript CG33122-RA 0.012
ERR estrogen-related receptor 0.012
CG4447 CG4447 gene product from transcript CG4447-RA 0.012
nito spenito 0.012
Atg7 Autophagy-specific gene 7 0.011
CG17294 CG17294 gene product from transcript CG17294-RA 0.011
AP-1gamma CG9113 gene product from transcript CG9113-RD 0.011
bur burgundy 0.011
al aristaless 0.011
p115 CG1422 gene product from transcript CG1422-RA 0.011
BG4 CG12297 gene product from transcript CG12297-RA 0.011
hk hook 0.011
rev7 CG2948 gene product from transcript CG2948-RA 0.011
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Homo sapiens
Name Description Probability Func Analog Organism
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 0.761
PLDN pallidin homolog (mouse) 0.731
DTNBP1 dystrobrevin binding protein 1 0.523
VIPAR VPS33B interacting protein, apical-basolateral polarity regulator 0.517
RAB27A RAB27A, member RAS oncogene family 0.204
OCRL oculocerebrorenal syndrome of Lowe 0.133
RAB14 RAB14, member RAS oncogene family 0.089
CTNND1 catenin (cadherin-associated protein), delta 1 0.089
DSG2 desmoglein 2 0.083
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.076
RAB10 RAB10, member RAS oncogene family 0.058
CLASP1 cytoplasmic linker associated protein 1 0.054
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.049
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.044
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.040
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.037
SNAPIN SNAP-associated protein 0.035
MLPH melanophilin 0.035
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.033
BCL2L1 BCL2-like 1 0.031
RAB6A RAB6A, member RAS oncogene family 0.029
RABIF RAB interacting factor 0.028
MAPK1 mitogen-activated protein kinase 1 0.027
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.027
KIF23 kinesin family member 23 0.024
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.023
NEU1 sialidase 1 (lysosomal sialidase) 0.022
AGFG1 ArfGAP with FG repeats 1 0.022
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.019
YAP1 Yes-associated protein 1 0.019
PEBP4 phosphatidylethanolamine-binding protein 4 0.019
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.018
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.017
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.017
MTF1 metal-regulatory transcription factor 1 0.017
TIMP1 TIMP metallopeptidase inhibitor 1 0.015
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.015
BBS2 Bardet-Biedl syndrome 2 0.015
JUP junction plakoglobin 0.014
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.013
RAB11FIP2 RAB11 family interacting protein 2 (class I) 0.013
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.012
LDOC1 leucine zipper, down-regulated in cancer 1 0.012
NAGK N-acetylglucosamine kinase 0.012
MYO5A myosin VA (heavy chain 12, myoxin) 0.012
CD9 CD9 molecule 0.012
DUSP3 dual specificity phosphatase 3 0.012
CCDC53 coiled-coil domain containing 53 0.012
LAMP1 lysosomal-associated membrane protein 1 0.011
CLINT1 clathrin interactor 1 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism