IMP
Process View
The network for 'regulation of renin secretion into blood stream' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of renin secretion into blood stream
Any process that modulates the frequency, rate or extent of renin secretion into blood stream.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Scn5a | sodium channel, voltage-gated, type V, alpha | 1.000 | |
| Tbx5 | T-box 5 | 0.996 | |
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.984 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.974 | |
| Tjp1 | tight junction protein 1 | 0.854 | |
| Ryr2 | ryanodine receptor 2, cardiac | 0.818 | |
| Gjb6 | gap junction protein, beta 6 | 0.674 | |
| Pcdh12 | protocadherin 12 | 0.621 | |
| Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.609 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.603 | |
| Tbx3 | T-box 3 | 0.573 | |
| Phldb2 | pleckstrin homology-like domain, family B, member 2 | 0.494 | |
| Gjb2 | gap junction protein, beta 2 | 0.458 | |
| Kel | Kell blood group | 0.396 | |
| Adrb3 | adrenergic receptor, beta 3 | 0.314 | |
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.287 | |
| Gjb4 | gap junction protein, beta 4 | 0.224 | |
| Wnt7a | wingless-related MMTV integration site 7A | 0.211 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.208 | |
| Klk6 | kallikrein related-peptidase 6 | 0.190 | |
| Il1f5 | interleukin 1 family, member 5 (delta) | 0.180 | |
| Aplnr | apelin receptor | 0.178 | |
| Dsc1 | desmocollin 1 | 0.172 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.166 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.165 | |
| Ern2 | endoplasmic reticulum (ER) to nucleus signalling 2 | 0.161 | |
| Fut2 | fucosyltransferase 2 | 0.154 | |
| Rhox6 | reproductive homeobox 6 | 0.144 | |
| Tmem40 | transmembrane protein 40 | 0.141 | |
| Fut1 | fucosyltransferase 1 | 0.139 | |
| Hopx | HOP homeobox | 0.129 | |
| Krt5 | keratin 5 | 0.123 | |
| Ivl | involucrin | 0.123 | |
| Csda | cold shock domain protein A | 0.122 | |
| Cyp2d10 | cytochrome P450, family 2, subfamily d, polypeptide 10 | 0.121 | |
| Cdh1 | cadherin 1 | 0.120 | |
| Kcne1l | potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene | 0.118 | |
| Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | 0.116 | |
| Sstr3 | somatostatin receptor 3 | 0.112 | |
| Foxd2 | forkhead box D2 | 0.110 | |
| Csf1r | colony stimulating factor 1 receptor | 0.109 | |
| Vim | vimentin | 0.108 | |
| Dmd | dystrophin, muscular dystrophy | 0.108 | |
| Krt17 | keratin 17 | 0.105 | |
| Slc26a4 | solute carrier family 26, member 4 | 0.104 | |
| Mt4 | metallothionein 4 | 0.104 | |
| Slurp1 | secreted Ly6/Plaur domain containing 1 | 0.104 | |
| Krt31 | keratin 31 | 0.103 | |
| Slc5a11 | solute carrier family 5 (sodium/glucose cotransporter), member 11 | 0.099 | |
| Gata6 | GATA binding protein 6 | 0.096 | |
| Gucy2e | guanylate cyclase 2e | 0.095 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.090 | |
| Rem1 | rad and gem related GTP binding protein 1 | 0.089 | |
| Dmkn | dermokine | 0.087 | |
| Sox7 | SRY-box containing gene 7 | 0.083 | |
| Nid1 | nidogen 1 | 0.081 | |
| Sstr1 | somatostatin receptor 1 | 0.081 | |
| Htr3b | 5-hydroxytryptamine (serotonin) receptor 3B | 0.081 | |
| Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.080 | |
| Bmp2 | bone morphogenetic protein 2 | 0.080 | |
| Krtap3-3 | keratin associated protein 3-3 | 0.079 | |
| Gja5 | gap junction protein, alpha 5 | 0.079 | |
| Gabrq | gamma-aminobutyric acid (GABA) A receptor, subunit theta | 0.078 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.078 | |
| Krtap3-1 | keratin associated protein 3-1 | 0.077 | |
| Pde3a | phosphodiesterase 3A, cGMP inhibited | 0.077 | |
| Kcnk7 | potassium channel, subfamily K, member 7 | 0.074 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.073 | |
| Slc16a8 | solute carrier family 16 (monocarboxylic acid transporters), member 8 | 0.073 | |
| Krt15 | keratin 15 | 0.072 | |
| Gjb3 | gap junction protein, beta 3 | 0.072 | |
| Cldn6 | claudin 6 | 0.071 | |
| Mog | myelin oligodendrocyte glycoprotein | 0.071 | |
| Tff2 | trefoil factor 2 (spasmolytic protein 1) | 0.071 | |
| Marco | macrophage receptor with collagenous structure | 0.070 | |
| Defa-rs12 | defensin, alpha, related sequence 12 | 0.069 | |
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.069 | |
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.069 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.069 | |
| Fgf17 | fibroblast growth factor 17 | 0.066 | |
| Clic3 | chloride intracellular channel 3 | 0.066 | |
| Fgg | fibrinogen gamma chain | 0.064 | |
| Dsg2 | desmoglein 2 | 0.064 | |
| Edn2 | endothelin 2 | 0.063 | |
| Htr5a | 5-hydroxytryptamine (serotonin) receptor 5A | 0.063 | |
| Fcgbp | Fc fragment of IgG binding protein | 0.063 | |
| Itih3 | inter-alpha trypsin inhibitor, heavy chain 3 | 0.061 | |
| F12 | coagulation factor XII (Hageman factor) | 0.059 | |
| Podxl | podocalyxin-like | 0.059 | |
| Wfdc2 | WAP four-disulfide core domain 2 | 0.059 | |
| Elf5 | E74-like factor 5 | 0.058 | |
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.057 | |
| G6pc2 | glucose-6-phosphatase, catalytic, 2 | 0.057 | |
| Atp4b | ATPase, H+/K+ exchanging, beta polypeptide | 0.057 | |
| Crct1 | cysteine-rich C-terminal 1 | 0.056 | |
| Gja1 | gap junction protein, alpha 1 | 0.056 | |
| Epx | eosinophil peroxidase | 0.056 | |
| Gpr87 | G protein-coupled receptor 87 | 0.056 | |
| Egfr | epidermal growth factor receptor | 0.055 | |
| Gpc3 | glypican 3 | 0.055 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Vdr | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.142 | |
| Olr1500 | olfactory receptor 1500 | 0.119 | |
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 0.108 | |
| Crhbp | corticotropin releasing hormone binding protein | 0.102 | |
| Galnt5 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) | 0.082 | |
| Fgf14 | fibroblast growth factor 14 | 0.082 | |
| Ar | androgen receptor | 0.074 | |
| Gja3 | gap junction protein, alpha 3 | 0.067 | |
| Cga | glycoprotein hormones, alpha polypeptide | 0.066 | |
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.062 | |
| Tacr2 | tachykinin receptor 2 | 0.060 | |
| Kcnh7 | potassium voltage-gated channel, subfamily H (eag-related), member 7 | 0.050 | |
| Fam70b | family with sequence similarity 70, member B | 0.049 | |
| Syt8 | synaptotagmin VIII | 0.047 | |
| Ier5 | immediate early response 5 | 0.046 | |
| Dusp4 | dual specificity phosphatase 4 | 0.044 | |
| Pth | parathyroid hormone | 0.041 | |
| Dlx5 | distal-less homeobox 5 | 0.041 | |
| Il6 | interleukin 6 | 0.040 | |
| Edn1 | endothelin 1 | 0.040 | |
| Olr416 | olfactory receptor 416 | 0.040 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.038 | |
| Cma1 | chymase 1, mast cell | 0.038 | |
| Olr1278 | olfactory receptor 1278 | 0.038 | |
| Trpc4 | transient receptor potential cation channel, subfamily C, member 4 | 0.037 | |
| Strn | striatin, calmodulin binding protein | 0.037 | |
| Kcna3 | potassium voltage-gated channel, shaker-related subfamily, member 3 | 0.036 | |
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.036 | |
| Atp2b4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.036 | |
| RGD1564664 | similar to LOC387763 protein | 0.035 | |
| Hpcal4 | hippocalcin-like 4 | 0.035 | |
| Cckbr | cholecystokinin B receptor | 0.035 | |
| Svs3a | seminal vesicle secretory protein 3A | 0.033 | |
| LOC60591 | calcium-activated potassium channel beta subunit | 0.033 | |
| Ddn | dendrin | 0.033 | |
| Mmp12 | matrix metallopeptidase 12 | 0.033 | |
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.032 | |
| Ctrc | chymotrypsin C (caldecrin) | 0.032 | |
| Slc8a2 | solute carrier family 8 (sodium/calcium exchanger), member 2 | 0.032 | |
| Adora3 | adenosine A3 receptor | 0.032 | |
| Vcsa1 | variable coding sequence A1 | 0.031 | |
| Kalrn | kalirin, RhoGEF kinase | 0.031 | |
| RGD1564327 | similar to integrin alpha 8 | 0.031 | |
| Pcsk1 | proprotein convertase subtilisin/kexin type 1 | 0.031 | |
| Tnfsf4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.031 | |
| Gfi1 | growth factor independent 1 transcription repressor | 0.030 | |
| Cacnb1 | calcium channel, voltage-dependent, beta 1 subunit | 0.030 | |
| Grin2b | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.030 | |
| Drd1a | dopamine receptor D1A | 0.030 | |
| Csf3 | colony stimulating factor 3 (granulocyte) | 0.029 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.028 | |
| Il1rn | interleukin 1 receptor antagonist | 0.028 | |
| Fgf2 | fibroblast growth factor 2 | 0.028 | |
| Cdkn2b | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.027 | |
| Aqp5 | aquaporin 5 | 0.027 | |
| Hnmt | histamine N-methyltransferase | 0.027 | |
| Cxcl6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.027 | |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.027 | |
| Synpo | synaptopodin | 0.026 | |
| Sstr1 | somatostatin receptor 1 | 0.026 | |
| Npy1r | neuropeptide Y receptor Y1 | 0.026 | |
| Dck | deoxycytidine kinase | 0.026 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.026 | |
| Itpkb | inositol 1,4,5-trisphosphate 3-kinase B | 0.026 | |
| Prkcg | protein kinase C, gamma | 0.026 | |
| Tpsb2 | tryptase beta 2 | 0.026 | |
| Cd8b | CD8b molecule | 0.026 | |
| Erbb4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.026 | |
| Oprd1 | opioid receptor, delta 1 | 0.025 | |
| Gria1 | glutamate receptor, ionotropic, AMPA 1 | 0.025 | |
| Phkg1 | phosphorylase kinase, gamma 1 | 0.025 | |
| Cdh6 | cadherin 6 | 0.025 | |
| Gabrr1 | gamma-aminobutyric acid (GABA) receptor, rho 1 | 0.025 | |
| Chrm5 | cholinergic receptor, muscarinic 5 | 0.025 | |
| Fosl1 | fos-like antigen 1 | 0.025 | |
| Zp1 | zona pellucida glycoprotein 1 (sperm receptor) | 0.025 | |
| Mmp13 | matrix metallopeptidase 13 | 0.025 | |
| B3gat1 | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | 0.025 | |
| Csrnp2 | cysteine-serine-rich nuclear protein 2 | 0.024 | |
| Smad3 | SMAD family member 3 | 0.024 | |
| Grik1 | glutamate receptor, ionotropic, kainate 1 | 0.024 | |
| Foxe3 | forkhead box E3 | 0.024 | |
| RGD1562234 | similar to S100 calcium-binding protein, ventral prostate | 0.024 | |
| Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.024 | |
| Gpr6 | G protein-coupled receptor 6 | 0.024 | |
| Col10a1 | collagen, type X, alpha 1 | 0.024 | |
| Prrx1 | paired related homeobox 1 | 0.024 | |
| Chrna7 | cholinergic receptor, nicotinic, alpha 7 | 0.024 | |
| Ptafr | platelet-activating factor receptor | 0.023 | |
| Cyp21a1 | cytochrome P450, family 21, subfamily a, polypeptide 1 | 0.023 | |
| Slc2a3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.023 | |
| C1qtnf6 | C1q and tumor necrosis factor related protein 6 | 0.023 | |
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.023 | |
| Olr287 | olfactory receptor 287 | 0.023 | |
| Vip | vasoactive intestinal peptide | 0.023 | |
| Vom2r44 | vomeronasal 2 receptor 44 | 0.023 | |
| Rup2 | urinary protein 2 | 0.023 | |
| Prl3d1 | Prolactin family 3, subfamily d, member 1 | 0.022 | |
| Lsm6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.022 | |
| Il2ra | interleukin 2 receptor, alpha | 0.022 |