The network for 'defense response to other organism' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

defense response to other organism

Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.

Rattus norvegicus
Name Description Probability Func Analog Organism
Il1b interleukin 1 beta 0.595
Ptprc protein tyrosine phosphatase, receptor type, C 0.460
Cxcl10 chemokine (C-X-C motif) ligand 10 0.370
Slc15a3 solute carrier family 15, member 3 0.170
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.148
Neurl3 neuralized homolog 3 (Drosophila) 0.140
Unc5b unc-5 homolog B (C. elegans) 0.120
Vav1 vav 1 guanine nucleotide exchange factor 0.118
Il1a interleukin 1 alpha 0.111
Cnr2 cannabinoid receptor 2 (macrophage) 0.109
Igsf6 immunoglobulin superfamily, member 6 0.105
Zfp36 zinc finger protein 36 0.101
Mmp8 matrix metallopeptidase 8 0.101
Aif1 allograft inflammatory factor 1 0.095
Tgfbr2 transforming growth factor, beta receptor II 0.084
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.082
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.081
Hck hemopoietic cell kinase 0.077
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.077
Cd86 CD86 molecule 0.070
Cybb cytochrome b-245, beta polypeptide 0.068
Hpx hemopexin 0.066
Il2ra interleukin 2 receptor, alpha 0.066
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.066
Slfn2 schlafen 2 0.063
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.062
Hspb1 heat shock protein 1 0.059
Itgam integrin, alpha M 0.058
Inpp5d inositol polyphosphate-5-phosphatase D 0.057
Np4 defensin NP-4 precursor 0.056
Ccr5 chemokine (C-C motif) receptor 5 0.055
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.054
Tat tyrosine aminotransferase 0.051
Ncr1 natural cytotoxicity triggering receptor 1 0.050
Ubd ubiquitin D 0.050
Sell selectin L 0.047
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.047
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.046
Mca32 mast cell antigen 32 0.046
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.045
Slc12a4 solute carrier family 12 (potassium/chloride transporters), member 4 0.044
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.043
Syk spleen tyrosine kinase 0.043
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.043
Clec9a C-type lectin domain family 9, member a 0.042
Smad7 SMAD family member 7 0.041
Kynu kynureninase (L-kynurenine hydrolase) 0.041
Il7r interleukin 7 receptor 0.040
Calcb calcitonin-related polypeptide, beta 0.039
Casp12 caspase 12 0.039
Zfp260 zinc finger protein 260 0.039
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.038
Bdkrb1 bradykinin receptor B1 0.037
Dcc deleted in colorectal carcinoma 0.037
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.037
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.036
RGD1561143 similar to cell surface receptor FDFACT 0.036
Apol3 apolipoprotein L, 3 0.036
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.036
Reg3g regenerating islet-derived 3 gamma 0.036
Arhgap4 Rho GTPase activating protein 4 0.035
Lst1 leukocyte specific transcript 1 0.035
Il1rn interleukin 1 receptor antagonist 0.035
Il2rb interleukin 2 receptor, beta 0.035
Sirpa signal-regulatory protein alpha 0.035
Ccl3 chemokine (C-C motif) ligand 3 0.035
Socs3 suppressor of cytokine signaling 3 0.035
Hand2 heart and neural crest derivatives expressed 2 0.034
Cd2 Cd2 molecule 0.033
Gabrr2 gamma-aminobutyric acid (GABA) receptor, rho 2 0.033
Chrm2 cholinergic receptor, muscarinic 2 0.032
Dnase1l3 deoxyribonuclease 1-like 3 0.032
Capns1 calpain, small subunit 1 0.031
Phc2 polyhomeotic homolog 2 (Drosophila) 0.031
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.031
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.031
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.031
Icam1 intercellular adhesion molecule 1 0.030
Gch1 GTP cyclohydrolase 1 0.030
Ptafr platelet-activating factor receptor 0.030
Adcy10 adenylate cyclase 10 (soluble) 0.030
Mx1 myxovirus (influenza virus) resistance 1 0.029
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.029
Ripk3 receptor-interacting serine-threonine kinase 3 0.029
Nras neuroblastoma ras oncogene 0.029
Pld1 phospholipase D1 0.029
Prlh prolactin releasing hormone 0.028
Cav1 caveolin 1, caveolae protein 0.028
RT1-Db1 RT1 class II, locus Db1 0.028
Casp1 caspase 1 0.028
Cd37 CD37 molecule 0.028
Lrp10 low-density lipoprotein receptor-related protein 10 0.028
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.028
Syngr2 synaptogyrin 2 0.027
Jak1 Janus kinase 1 0.027
LOC100361261 rCG23560-like 0.027
LOC100363700 probable N-acetyltransferase CML4-like 0.027
Apob apolipoprotein B 0.027
Myh9 myosin, heavy chain 9, non-muscle 0.026
Gfi1 growth factor independent 1 transcription repressor 0.026
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
CELE_C17H12.8 Protein C17H12.8 0.744
dod-24 Protein DOD-24 0.681
hsp-16.2 Protein HSP-16.2 0.654
scl-2 Protein SCL-2 0.596
hsp-17 Protein HSP-17 0.591
col-157 Protein COL-157 0.570
ilys-3 Protein ILYS-3 0.561
lys-2 Protein LYS-2 0.521
hsp-16.1 Protein HSP-16.1 0.489
hsp-16.41 Protein HSP-16.41 0.473
cpr-1 Protein CPR-1 0.460
clec-52 Protein CLEC-52 0.457
hsp-70 Protein HSP-70 0.443
col-34 Protein COL-34 0.437
ncs-2 Protein NCS-2 0.433
clec-67 Protein CLEC-67 0.396
CELE_F55G11.8 Protein F55G11.8 0.390
dpy-13 Protein DPY-13 0.377
daf-14 Protein DAF-14 0.337
dpy-4 Protein DPY-4 0.333
F44E5.4 Protein F44E5.4 0.315
lys-7 Protein LYS-7 0.314
col-43 Protein COL-43 0.308
C34H4.1 Protein C34H4.1 0.304
col-93 Protein COL-93 0.294
clec-63 Protein CLEC-63 0.289
egl-18 Protein EGL-18 0.273
col-133 Protein COL-133 0.260
col-159 Protein COL-159 0.258
ZK970.7 Protein ZK970.7 0.258
hpo-6 Protein HPO-6 0.257
col-103 Protein COL-103 0.255
pgp-6 Protein PGP-6 0.248
CELE_K08D8.5 Protein K08D8.5 0.238
CELE_C32H11.4 Protein C32H11.4 0.233
daf-11 Protein DAF-11 0.220
sqt-3 Protein SQT-3 0.215
col-154 Protein COL-154 0.215
thn-1 Protein THN-1 0.212
hsp-16.48 Protein HSP-16.48 0.212
cnc-4 Protein CNC-4 0.203
col-2 Protein COL-2 0.197
rol-8 Protein ROL-8 0.184
W01A11.1 Protein W01A11.1 0.184
col-104 Protein COL-104 0.184
col-184 Protein COL-184 0.183
col-146 Protein COL-146 0.181
rol-6 Protein ROL-6 0.181
cnc-2 Protein CNC-2 0.179
nhr-50 Protein NHR-50 0.177
lys-6 Protein LYS-6 0.175
clec-174 Protein CLEC-174 0.175
dpy-7 Protein DPY-7 0.174
col-92 Protein COL-92 0.174
C46C11.3 Protein C46C11.3 0.172
CELE_C17F4.7 Protein C17F4.7 0.168
sqt-1 Protein SQT-1 0.161
spp-4 Protein SPP-4 0.157
sem-5 Protein SEM-5 0.157
cct-2 Protein CCT-2 0.156
php-3 Protein PHP-3 0.154
lipl-2 Protein LIPL-2 0.153
col-80 Protein COL-80 0.145
magu-2 Protein MAGU-2 0.144
col-84 Protein COL-84 0.141
col-49 Protein COL-49 0.140
ech-6 Protein ECH-6 0.138
lys-4 Protein LYS-4 0.138
CELE_ZK896.4 Protein ZK896.4 0.138
nlp-30 Protein NLP-30 0.138
col-13 Protein COL-13 0.137
col-73 Protein COL-73 0.136
col-144 Protein COL-144 0.135
thn-2 Protein THN-2 0.134
irg-1 Protein IRG-1 0.130
col-180 Protein COL-180 0.127
dpy-2 Protein DPY-2 0.121
F28H7.3 Protein F28H7.3 0.121
col-181 Protein COL-181 0.120
nlp-39 Protein NLP-39 0.119
cyn-6 Protein CYN-6 0.119
unc-54 Protein UNC-54 0.119
col-156 Protein COL-156 0.117
F22H10.3 Protein F22H10.3 0.117
dpy-3 Protein DPY-3 0.116
hlh-2 Protein HLH-2 0.116
pmk-3 Protein PMK-3 0.116
B0035.6 Protein B0035.6 0.114
C50F7.5 Protein C50F7.5 0.111
prx-12 Protein PRX-12 0.110
col-114 Protein COL-114 0.110
dpy-8 Protein DPY-8 0.109
CELE_K08D8.4 Protein K08D8.4 0.108
K10C2.3 Protein K10C2.3 0.108
CELE_M01G12.9 Protein M01G12.9 0.107
col-147 Protein COL-147 0.105
F27E5.1 Protein F27E5.1 0.104
daf-1 Protein DAF-1 0.103
T23F4.2 Protein T23F4.2 0.102
sek-1 Protein SEK-1 0.101
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
irf6 interferon regulatory factor 6 0.734
tlr21 toll-like receptor 21 0.709
rnasel1 ribonuclease like 1 0.694
mmp9 matrix metalloproteinase 9 0.669
mmp14a matrix metalloproteinase 14a (membrane-inserted) 0.655
nanos3 nanos homolog 3 0.590
fgfr3 fibroblast growth factor receptor 3 0.527
LOC557072 caspase recruitment domain-containing protein 11-like 0.523
nod1 nucleotide-binding oligomerization domain containing 1 0.477
pglyrp2 peptidoglycan recognition protein 2 0.444
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.421
nod2 nucleotide-binding oligomerization domain containing 2 0.416
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.372
tbx1 T-box 1 0.365
fes feline sarcoma oncogene 0.352
c1qc complement component 1, q subcomponent, C chain 0.325
wnt10a wingless-type MMTV integration site family, member 10a 0.311
sult2st3 sulfotransferase family 2, cytosolic sulfotransferase 3 0.309
tlr3 toll-like receptor 3 0.309
dlb deltaB 0.305
nos2a nitric oxide synthase 2a, inducible 0.294
adipor2 adiponectin receptor 2 0.294
rhogb ras homolog gene family, member Gb 0.294
bmp2b bone morphogenetic protein 2b 0.291
fas Fas (TNF receptor superfamily, member 6) 0.274
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.268
runx2b runt-related transcription factor 2b 0.240
pycard PYD and CARD domain containing 0.238
angptl2 angiopoietin-like 2 0.233
eng2a engrailed 2a 0.209
prkar1aa protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a 0.203
ctsl1a cathepsin L, 1 a 0.203
ahr2 aryl hydrocarbon receptor 2 0.201
myf5 myogenic factor 5 0.197
comta catechol-O-methyltransferase a 0.196
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.195
tlr9 toll-like receptor 9 0.190
atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.185
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.185
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.179
wnt8a wingless-type MMTV integration site family, member 8a 0.172
gpib glucose phosphate isomerase b 0.170
il6st interleukin 6 signal transducer 0.169
calca calcitonin/calcitonin-related polypeptide, alpha 0.168
fgf4 fibroblast growth factor 4 0.168
tnfb tumor necrosis factor b (TNF superfamily, member 2) 0.165
tnfsf10l2 tumor necrosis factor (ligand) superfamily, member 10 like 2 0.163
fam49ba family with sequence similarity 49, member Ba 0.161
tgfb1a transforming growth factor, beta 1a 0.157
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.154
fgf20a fibroblast growth factor 20a 0.154
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.152
otpb orthopedia homolog b 0.150
adipoql adiponectin, C1Q and collagen domain containing, like 0.148
ighm immunoglobulin heavy constant mu and immunoglobulin heavy constant mu 0.146
axin2 axin 2 (conductin, axil) 0.142
il7r interleukin 7 receptor 0.136
tp53 tumor protein p53 0.134
ifnphi1 interferon phi 1 0.132
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.124
tlr18 toll-like receptor 18 0.122
igf1 insulin-like growth factor 1 0.121
zgc:113210 zgc:113210 0.120
smyhc1 slow myosin heavy chain 1 0.118
il17rd interleukin 17 receptor D 0.116
bmp2a bone morphogenetic protein 2a 0.116
igf1ra insulin-like growth factor 1a receptor 0.116
wnt9b wingless-type MMTV integration site family, member 9B 0.113
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.111
lef1 lymphocyte enhancer binding factor 1 0.109
vtg6 vitellogenin 6 0.106
map1lc3b microtubule-associated protein 1 light chain 3 beta 0.103
caspa caspase a 0.101
hgfa hepatocyte growth factor a 0.100
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.099
scinla scinderin like a 0.097
card9 caspase recruitment domain family, member 9 0.092
LOC100000934 hypothetical protein LOC100000934 0.092
rcn1 reticulocalbin 1, EF-hand calcium binding domain 0.091
stat3 signal transduction and activation of transcription 3 0.090
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.090
ctsf cathepsin F 0.088
foxi3a forkhead box I3a 0.088
tal1 T-cell acute lymphocytic leukemia 1 0.087
sri sorcin 0.084
ndr1 nodal-related 1 0.084
otul OTU like protein 0.084
runx3 runt-related transcription factor 3 0.082
rhag Rhesus blood group-associated glycoprotein 0.081
runx2a runt-related transcription factor 2a 0.081
ripk2 receptor-interacting serine-threonine kinase 2 0.080
timp2a tissue inhibitor of metalloproteinase 2a 0.079
card14 caspase recruitment domain family, member 14 0.079
mpzl2 myelin protein zero-like 2 0.078
si:dkey-236e20.2 si:dkey-236e20.2 0.078
dlc deltaC 0.078
aqp8a.2 aquaporin 8a, tandem duplicate 2 0.077
anxa5b annexin A5b 0.076
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.076
itga2b integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) 0.073
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
PGRP-LC Peptidoglycan recognition protein LC 0.999
AttA Attacin-A 0.998
spz spatzle 0.994
Rel Relish 0.992
Rho1 CG8416 gene product from transcript CG8416-RB 0.972
Pvr PDGF- and VEGF-receptor related 0.964
AGO2 Argonaute 2 0.960
grass Gram-positive Specific Serine protease 0.944
Jon99Ciii Jonah 99Ciii 0.942
SPE Spatzle-Processing Enzyme 0.940
Glt Glutactin 0.938
Traf4 TNF-receptor-associated factor 4 0.929
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.925
DptB Diptericin B 0.922
PGRP-SA Peptidoglycan recognition protein SA 0.910
Rbf Retinoblastoma-family protein 0.907
CG6361 CG6361 gene product from transcript CG6361-RA 0.888
Fmr1 CG6203 gene product from transcript CG6203-RC 0.869
Drs Drosomycin 0.858
Spn27A Serpin 27A 0.852
Pten CG5671 gene product from transcript CG5671-RB 0.847
Rab7 Rab-protein 7 0.847
IM18 Immune induced molecule 18 0.841
CG32185 CG32185 gene product from transcript CG32185-RA 0.828
ird5 immune response deficient 5 0.825
key kenny 0.824
Spn1 Serine protease inhibitor 1 0.808
egr eiger 0.800
dome domeless 0.785
lic licorne 0.778
fon fondue 0.777
Tak1 TGF-beta activated kinase 1 0.774
CG13422 CG13422 gene product from transcript CG13422-RA 0.769
Nrx-IV Neurexin IV 0.763
imd immune deficiency 0.747
CG12004 CG12004 gene product from transcript CG12004-RC 0.741
Lsp1alpha Larval serum protein 1 alpha 0.740
CG15065 CG15065 gene product from transcript CG15065-RA 0.736
lwr lesswright 0.731
Hsf Heat shock factor 0.731
CG18594 CG18594 gene product from transcript CG18594-RA 0.729
Sp7 Serine protease 7 0.727
CalpA Calpain-A 0.717
Rab2 Rab-protein 2 0.713
Irc Immune-regulated catalase 0.704
CecC Cecropin C 0.704
Mpk2 CG5475 gene product from transcript CG5475-RB 0.701
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.682
bsk basket 0.669
GNBP1 Gram-negative bacteria binding protein 1 0.665
os outstretched 0.648
Mtk Metchnikowin 0.645
Jon25Bii Jonah 25Bii 0.639
Trx-2 thioredoxin-2 0.620
Atg1 Autophagy-specific gene 1 0.601
Mad Mothers against dpp 0.601
CG15917 CG15917 gene product from transcript CG15917-RA 0.579
aop anterior open 0.572
Amy-d Amylase distal 0.554
Stam Signal transducing adaptor molecule 0.552
PGRP-LF Peptidoglycan recognition protein LF 0.545
Jon65Aiii Jonah 65Aiii 0.519
GNBP3 Gram-negative bacteria binding protein 3 0.513
epsilonTry epsilonTrypsin 0.500
CG7320 CG7320 gene product from transcript CG7320-RA 0.495
Spn28D Serpin 28D 0.485
Dredd Death related ced-3/Nedd2-like protein 0.484
Dpt Diptericin 0.482
spi spitz 0.477
Hsp22 Heat shock protein 22 0.475
kay kayak 0.459
pie pineapple eye 0.453
CG16718 CG16718 gene product from transcript CG16718-RA 0.448
CecA2 Cecropin A2 0.447
ird1 immune response deficient 1 0.444
Dro Drosocin 0.440
Pp1-87B Protein phosphatase 1 at 87B 0.436
IM1 Immune induced molecule 1 0.436
modSP modular serine protease 0.426
spheroide CG9675 gene product from transcript CG9675-RA 0.425
msn misshapen 0.415
AttC Attacin-C 0.413
pirk poor Imd response upon knock-in 0.402
Unc-76 CG3981 gene product from transcript CG3981-RB 0.401
CHORD CG6198 gene product from transcript CG6198-RA 0.386
PGRP-LB Peptidoglycan recognition protein LB 0.384
IM4 Immune induced molecule 4 0.382
TM9SF4 CG7364 gene product from transcript CG7364-RA 0.382
He Hemese 0.381
pll pelle 0.378
pasha partner of drosha 0.372
Moe Moesin 0.369
betaTry betaTrypsin 0.368
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.366
eater CG6124 gene product from transcript CG6124-RB 0.360
Jafrac1 thioredoxin peroxidase 1 0.359
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.359
Duox Dual oxidase 0.357
Sin3A CG8815 gene product from transcript CG8815-RC 0.355
CG3868 CG3868 gene product from transcript CG3868-RA 0.348
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
STAT1 signal transducer and activator of transcription 1, 91kDa 1.000
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.999
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.996
IFI44 interferon-induced protein 44 0.995
BCL2 B-cell CLL/lymphoma 2 0.993
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.993
SP110 SP110 nuclear body protein 0.990
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.988
PLSCR1 phospholipid scramblase 1 0.987
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.981
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.980
MYD88 myeloid differentiation primary response gene (88) 0.975
ISG15 ISG15 ubiquitin-like modifier 0.972
SMAD4 SMAD family member 4 0.970
IRAK1 interleukin-1 receptor-associated kinase 1 0.968
MX2 myxovirus (influenza virus) resistance 2 (mouse) 0.952
S100A6 S100 calcium binding protein A6 0.950
HIST1H2BD histone cluster 1, H2bd 0.926
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.914
IFI44L interferon-induced protein 44-like 0.909
HIST1H2BE histone cluster 1, H2be 0.905
HIST1H2BF histone cluster 1, H2bf 0.900
MAPK14 mitogen-activated protein kinase 14 0.899
SP100 SP100 nuclear antigen 0.881
GBP1 guanylate binding protein 1, interferon-inducible 0.871
PML promyelocytic leukemia 0.870
IFITM1 interferon induced transmembrane protein 1 (9-27) 0.867
IL8 interleukin 8 0.863
HSPB1 heat shock 27kDa protein 1 0.856
RIPK2 receptor-interacting serine-threonine kinase 2 0.837
OAS1 2',5'-oligoadenylate synthetase 1, 40/46kDa 0.836
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.834
OASL 2'-5'-oligoadenylate synthetase-like 0.827
HIST1H2AC histone cluster 1, H2ac 0.821
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.811
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.811
SQSTM1 sequestosome 1 0.804
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.802
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.799
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.792
IFIH1 interferon induced with helicase C domain 1 0.788
IL4R interleukin 4 receptor 0.771
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.764
EGFR epidermal growth factor receptor 0.761
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.758
S100A8 S100 calcium binding protein A8 0.746
PYCARD PYD and CARD domain containing 0.744
CREBBP CREB binding protein 0.734
BIRC3 baculoviral IAP repeat containing 3 0.728
XAF1 XIAP associated factor 1 0.728
UBC ubiquitin C 0.701
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.684
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.676
SOCS1 suppressor of cytokine signaling 1 0.675
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.672
FGF1 fibroblast growth factor 1 (acidic) 0.642
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.642
TRIM22 tripartite motif containing 22 0.630
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.620
IRF7 interferon regulatory factor 7 0.620
PPL periplakin 0.604
HIST1H1C histone cluster 1, H1c 0.602
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 0.598
SAMD9 sterile alpha motif domain containing 9 0.595
IFI16 interferon, gamma-inducible protein 16 0.595
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.590
ATF2 activating transcription factor 2 0.590
IRF9 interferon regulatory factor 9 0.590
MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 0.580
HIST1H2BG histone cluster 1, H2bg 0.575
HIST1H2BH histone cluster 1, H2bh 0.572
OCRL oculocerebrorenal syndrome of Lowe 0.563
HIST1H2BK histone cluster 1, H2bk 0.561
S100A9 S100 calcium binding protein A9 0.558
GBP2 guanylate binding protein 2, interferon-inducible 0.557
IGSF6 immunoglobulin superfamily, member 6 0.556
RSAD2 radical S-adenosyl methionine domain containing 2 0.556
HIST1H2BC histone cluster 1, H2bc 0.555
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.554
FGFR1 fibroblast growth factor receptor 1 0.553
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.552
CYBB cytochrome b-245, beta polypeptide 0.545
HIST1H2BI histone cluster 1, H2bi 0.536
SMAD3 SMAD family member 3 0.532
ANXA2 annexin A2 0.530
CHUK conserved helix-loop-helix ubiquitous kinase 0.530
IL6 interleukin 6 (interferon, beta 2) 0.519
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.511
PARP12 poly (ADP-ribose) polymerase family, member 12 0.511
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.505
ALOX5 arachidonate 5-lipoxygenase 0.504
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 0.492
SAMD9L sterile alpha motif domain containing 9-like 0.477
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.477
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.472
BMP2 bone morphogenetic protein 2 0.458
PLAU plasminogen activator, urokinase 0.457
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.449
BCL2L1 BCL2-like 1 0.432
HIST1H3D histone cluster 1, H3d 0.412
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Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 1.000
Fas Fas (TNF receptor superfamily member 6) 1.000
Casp4 caspase 4, apoptosis-related cysteine peptidase 1.000
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 1.000
Myd88 myeloid differentiation primary response gene 88 0.999
Lyz2 lysozyme 2 0.999
Tlr4 toll-like receptor 4 0.999
Casp1 caspase 1 0.998
Il10 interleukin 10 0.996
Stat1 signal transducer and activator of transcription 1 0.996
Pten phosphatase and tensin homolog 0.996
Cd40 CD40 antigen 0.995
Gbp7 guanylate binding protein 7 0.994
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.993
Igh immunoglobulin heavy chain complex 0.991
Gbp2 guanylate binding protein 2 0.991
Trim30a tripartite motif-containing 30A 0.990
Ifng interferon gamma 0.990
Stat3 signal transducer and activator of transcription 3 0.989
Ptgs2 prostaglandin-endoperoxide synthase 2 0.987
Nlrp3 NLR family, pyrin domain containing 3 0.987
Ccl4 chemokine (C-C motif) ligand 4 0.986
Ccl2 chemokine (C-C motif) ligand 2 0.983
Nos2 nitric oxide synthase 2, inducible 0.983
Ptprc protein tyrosine phosphatase, receptor type, C 0.983
Trim21 tripartite motif-containing 21 0.983
Ikzf1 IKAROS family zinc finger 1 0.983
Mapk14 mitogen-activated protein kinase 14 0.980
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.980
Irf7 interferon regulatory factor 7 0.977
Il1b interleukin 1 beta 0.975
Clec4d C-type lectin domain family 4, member d 0.975
Gzmb granzyme B 0.974
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.971
Ifi47 interferon gamma inducible protein 47 0.970
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.962
Il6 interleukin 6 0.961
Sfpi1 SFFV proviral integration 1 0.961
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.961
Birc3 baculoviral IAP repeat-containing 3 0.958
Irgm1 immunity-related GTPase family M member 1 0.956
Clec4n C-type lectin domain family 4, member n 0.955
Gbp3 guanylate binding protein 3 0.954
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.953
Gbp1 guanylate binding protein 1 0.951
Irf1 interferon regulatory factor 1 0.946
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.946
Ifih1 interferon induced with helicase C domain 1 0.945
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.945
Batf basic leucine zipper transcription factor, ATF-like 0.941
Stat6 signal transducer and activator of transcription 6 0.939
Trem3 triggering receptor expressed on myeloid cells 3 0.938
Pparg peroxisome proliferator activated receptor gamma 0.938
Il1rn interleukin 1 receptor antagonist 0.938
Iigp1 interferon inducible GTPase 1 0.937
Slfn4 schlafen 4 0.936
Cd96 CD96 antigen 0.933
Itgal integrin alpha L 0.933
Atf2 activating transcription factor 2 0.932
Cd28 CD28 antigen 0.929
Cd180 CD180 antigen 0.929
Siglece sialic acid binding Ig-like lectin E 0.928
Ifi203 interferon activated gene 203 0.926
Icos inducible T-cell co-stimulator 0.925
Fcgr1 Fc receptor, IgG, high affinity I 0.916
Ccr2 chemokine (C-C motif) receptor 2 0.915
Il1r1 interleukin 1 receptor, type I 0.913
Klra2 killer cell lectin-like receptor, subfamily A, member 2 0.912
Ccr1 chemokine (C-C motif) receptor 1 0.911
Csf1 colony stimulating factor 1 (macrophage) 0.910
Ctsg cathepsin G 0.910
Irf9 interferon regulatory factor 9 0.907
Selp selectin, platelet 0.906
Cd44 CD44 antigen 0.905
Cd14 CD14 antigen 0.905
Rtp4 receptor transporter protein 4 0.895
Apoe apolipoprotein E 0.894
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.894
Fcgr4 Fc receptor, IgG, low affinity IV 0.884
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.883
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.881
Fpr2 formyl peptide receptor 2 0.881
Il10ra interleukin 10 receptor, alpha 0.879
Il2rg interleukin 2 receptor, gamma chain 0.877
AF251705 cDNA sequence AF251705 0.870
Pyhin1 pyrin and HIN domain family, member 1 0.862
Fasl Fas ligand (TNF superfamily, member 6) 0.860
Tlr2 toll-like receptor 2 0.857
Ccr7 chemokine (C-C motif) receptor 7 0.856
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.851
Clec4e C-type lectin domain family 4, member e 0.849
Oas3 2'-5' oligoadenylate synthetase 3 0.844
Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b 0.842
Tgtp2 T-cell specific GTPase 2 0.841
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.841
Bcl3 B-cell leukemia/lymphoma 3 0.841
Casp8 caspase 8 0.839
Pycard PYD and CARD domain containing 0.838
Ticam1 toll-like receptor adaptor molecule 1 0.838
Cxcl10 chemokine (C-X-C motif) ligand 10 0.836
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism