The network for 'axial mesoderm morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

axial mesoderm morphogenesis

The process in which the anatomical structures of the axial mesoderm are generated and organized.

Name Description Probability Func Analog Organism
flh floating head 0.850
pax2a paired box gene 2a 0.811
ntla no tail a 0.802
eya1 eyes absent homolog 1 0.536
oep one-eyed pinhead 0.454
foxa3 forkhead box A3 0.443
sox10 SRY-box containing gene 10 0.344
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.330
shha sonic hedgehog a 0.308
foxi3a forkhead box I3a 0.264
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.256
chd chordin 0.247
ndr2 nodal-related 2 0.231
crb2a crumbs homolog 2a 0.203
dharma dharma 0.176
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.170
cdx4 caudal type homeo box transcription factor 4 0.156
foxi3b forkhead box I3b 0.154
wnt11 wingless-type MMTV integration site family, member 11 0.134
sox2 SRY-box containing gene 2 0.130
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.126
pax6b paired box gene 6b 0.098
zgc:194131 zgc:194131 0.097
notch1a notch homolog 1a 0.086
atoh7 atonal homolog 7 0.085
neurod neurogenic differentiation 0.078
otx1b orthodenticle homolog 1b 0.078
mib mind bomb 0.074
tfe3b transcription factor binding to IGHM enhancer 3b 0.074
foxa2 forkhead box A2 0.072
ass1 argininosuccinate synthetase 1 0.068
pou5f1 POU domain, class 5, transcription factor 1 0.059
gata5 GATA-binding protein 5 0.057
jag1b jagged 1b 0.055
rx3 retinal homeobox gene 3 0.054
dld deltaD 0.053
slc4a1b solute carrier family 4, anion exchanger, member 1b 0.051
szl sizzled 0.051
fgf8a fibroblast growth factor 8 a 0.047
gli1 GLI-Kruppel family member 1 0.046
cldn5a claudin 5a 0.046
foxc1a forkhead box C1a 0.044
gata3 GATA-binding protein 3 0.040
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.040
foxi1 forkhead box I1 0.040
bmper BMP binding endothelial regulator 0.038
vasn vasorin 0.038
nkx2.2b NK2 transcription factor related 2b 0.038
krt4 keratin 4 0.036
vasa vasa homolog 0.035
dact2 dapper homolog 2, antagonist of beta-catenin (xenopus) 0.035
wnt7bb wingless-type MMTV integration site family, member 7Bb 0.034
pkp3 plakophilin 3 0.034
vsx2 visual system homeobox 2 0.034
dlc deltaC 0.033
fn1 fibronectin 1 0.031
fzd10 frizzled homolog 10 0.031
spns2 spinster homolog 2 (Drosophila) 0.030
dao.2 D-amino-acid oxidase 2 0.029
cdh1 cadherin 1, epithelial 0.028
sox32 SRY-box containing gene 32 0.028
fzd8a frizzled homolog 8a 0.027
hnf1ba HNF1 homeobox Ba 0.027
cdh2 cadherin 2, neuronal 0.026
tp63 tumor protein p63 0.026
hlxb9la homeo box HB9 like a 0.025
grhl2b grainyhead-like 2b (Drosophila) 0.023
nrarpa notch-regulated ankyrin repeat protein a 0.022
fgf3 fibroblast growth factor 3 0.022
six4b sine oculis homeobox homolog 4b 0.022
gata2a GATA-binding protein 2a 0.021
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.021
axin1 axin 1 0.021
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.020
lhx1a LIM homeobox 1a 0.020
nr2f5 nuclear receptor subfamily 2, group F, member 5 0.019
adipor2 adiponectin receptor 2 0.018
atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide 0.018
supt6h suppressor of Ty 6 homolog 0.018
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.018
nrf1 nuclear respiratory factor 1 0.017
six3a sine oculis homeobox homolog 3a 0.017
ctsl1b cathepsin L, 1 b 0.017
sox19a SRY-box containing gene 19a 0.017
tal2 T-cell acute lymphocytic leukemia 2 0.016
foxa1 forkhead box A1 0.016
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.016
vwf von Willebrand factor 0.015
tfa transferrin-a 0.015
pou1f1 POU domain, class 1, transcription factor 1 0.015
pard6gb par-6 partitioning defective 6 homolog gamma B (C. elegans) 0.015
vsx1 visual system homeobox 1 homolog, chx10-like 0.015
ccna1 cyclin A1 0.014
slc7a6 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 0.014
pitx2 paired-like homeodomain transcription factor 2 0.014
lef1 lymphocyte enhancer binding factor 1 0.013
gbx2 gastrulation brain homeo box 2 0.013
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.013
nkx2.3 NK2 transcription factor related 3 0.013
nkx2.1b NK2 homeobox 1b 0.013
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Lef1 lymphoid enhancer binding factor 1 0.837
Ctnnb1 catenin (cadherin associated protein), beta 1 0.635
Tcf7 transcription factor 7, T-cell specific 0.614
Bmp7 bone morphogenetic protein 7 0.574
Epha4 Eph receptor A4 0.485
Smad6 MAD homolog 6 (Drosophila) 0.440
Irs1 insulin receptor substrate 1 0.421
Zic3 zinc finger protein of the cerebellum 3 0.226
Kif3a kinesin family member 3A 0.205
Msx1 homeobox, msh-like 1 0.204
Fgfr2 fibroblast growth factor receptor 2 0.187
Efnb1 ephrin B1 0.159
Lrp6 low density lipoprotein receptor-related protein 6 0.137
Gsk3b glycogen synthase kinase 3 beta 0.132
Efnb2 ephrin B2 0.114
Ephb3 Eph receptor B3 0.111
Alx4 aristaless-like homeobox 4 0.097
Gli3 GLI-Kruppel family member GLI3 0.088
Shh sonic hedgehog 0.079
Gata4 GATA binding protein 4 0.078
Lrp5 low density lipoprotein receptor-related protein 5 0.077
Gas1 growth arrest specific 1 0.076
Kcnk2 potassium channel, subfamily K, member 2 0.073
Ephb2 Eph receptor B2 0.070
Tbx3 T-box 3 0.070
Gdf5 growth differentiation factor 5 0.067
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.063
Smad7 MAD homolog 7 (Drosophila) 0.061
Gli2 GLI-Kruppel family member GLI2 0.060
Rpgrip1l Rpgrip1-like 0.059
Hoxd13 homeobox D13 0.055
Nodal nodal 0.051
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.050
Msx2 homeobox, msh-like 2 0.047
Dlx5 distal-less homeobox 5 0.047
Dnahc11 dynein, axonemal, heavy chain 11 0.047
Smo smoothened homolog (Drosophila) 0.045
Bmp4 bone morphogenetic protein 4 0.043
Gata5 GATA binding protein 5 0.042
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.038
Gdf6 growth differentiation factor 6 0.038
Hand1 heart and neural crest derivatives expressed transcript 1 0.036
Fgfr3 fibroblast growth factor receptor 3 0.035
Otx2 orthodenticle homolog 2 (Drosophila) 0.034
Tcf7l1 transcription factor 7-like 1 (T-cell specific, HMG box) 0.033
Tbx2 T-box 2 0.029
Plxna4 plexin A4 0.027
Gata6 GATA binding protein 6 0.026
Tbx6 T-box 6 0.025
Ptk2 PTK2 protein tyrosine kinase 2 0.024
Gpc3 glypican 3 0.024
Sfrp2 secreted frizzled-related protein 2 0.023
Cldn3 claudin 3 0.023
Sult5a1 sulfotransferase family 5A, member 1 0.023
Pbx1 pre B-cell leukemia transcription factor 1 0.022
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.022
Syt2 synaptotagmin II 0.022
Tead2 TEA domain family member 2 0.021
Foxc1 forkhead box C1 0.021
Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.020
Meis2 Meis homeobox 2 0.020
Ptk7 PTK7 protein tyrosine kinase 7 0.019
Lhx1 LIM homeobox protein 1 0.019
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.019
Emid2 EMI domain containing 2 0.019
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.019
Cachd1 cache domain containing 1 0.018
Bnc1 basonuclin 1 0.018
Apc adenomatosis polyposis coli 0.018
Rnf111 ring finger 111 0.018
Wnt3a wingless-related MMTV integration site 3A 0.017
Iqcb1 IQ calmodulin-binding motif containing 1 0.017
Cdx2 caudal type homeobox 2 0.017
Wnt3 wingless-related MMTV integration site 3 0.017
Smad3 MAD homolog 3 (Drosophila) 0.016
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.016
Six2 sine oculis-related homeobox 2 homolog (Drosophila) 0.016
Pcsk6 proprotein convertase subtilisin/kexin type 6 0.016
Sox3 SRY-box containing gene 3 0.016
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.015
Mmp15 matrix metallopeptidase 15 0.015
Tcf21 transcription factor 21 0.015
Efna4 ephrin A4 0.015
Fzd8 frizzled homolog 8 (Drosophila) 0.015
Pnliprp2 pancreatic lipase-related protein 2 0.015
Pou3f1 POU domain, class 3, transcription factor 1 0.014
Sox11 SRY-box containing gene 11 0.014
Mecom MDS1 and EVI1 complex locus 0.014
Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.014
Fgf18 fibroblast growth factor 18 0.014
Fzd7 frizzled homolog 7 (Drosophila) 0.014
Gsc goosecoid homeobox 0.014
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.014
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.014
Cdh1 cadherin 1 0.014
Gdf1 growth differentiation factor 1 0.014
Mmp11 matrix metallopeptidase 11 0.013
Nfia nuclear factor I/A 0.013
Hnf4a hepatic nuclear factor 4, alpha 0.013
Efna3 ephrin A3 0.013
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism