The network for 'cardiac atrium development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cardiac atrium development

The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.

Danio rerio
Name Description Probability Func Analog Organism
kdrl kinase insert domain receptor like 0.864
mib mind bomb 0.735
ccm2 cerebral cavernous malformation 2 0.731
tbx1 T-box 1 0.679
fbn2b fibrillin 2b 0.644
fn1 fibronectin 1 0.633
tbx5a T-box 5a 0.633
alcama activated leukocyte cell adhesion molecule a 0.632
smyhc1 slow myosin heavy chain 1 0.590
cdh2 cadherin 2, neuronal 0.570
mef2cb myocyte enhancer factor 2cb 0.457
fli1a friend leukemia integration 1a 0.422
wnt11 wingless-type MMTV integration site family, member 11 0.370
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.351
tbx16 T-box gene 16 0.345
apc adenomatosis polyposis coli 0.333
clec14a C-type lectin domain family 14, member A 0.327
plcg1 phospholipase C, gamma 1 0.321
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.310
dld deltaD 0.309
vangl2 vang-like 2 (van gogh, Drosophila) 0.303
epb4.1l4 erythrocyte protein band 4.1-like 4 0.299
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.298
krit1 KRIT1, ankyrin repeat containing 0.289
tnnt2a troponin T2a, cardiac 0.277
bmp2b bone morphogenetic protein 2b 0.272
amotl2a angiomotin like 2a 0.209
pdlim7 PDZ and LIM domain 7 0.203
hhex hematopoietically expressed homeobox 0.202
trim33 tripartite motif-containing 33 0.195
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.190
bmp4 bone morphogenetic protein 4 0.182
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.171
chd chordin 0.166
gata5 GATA-binding protein 5 0.163
gata6 GATA-binding protein 6 0.151
hnf1ba HNF1 homeobox Ba 0.151
tpm4 tropomyosin 4 0.150
tnni1b troponin I, skeletal, slow b 0.145
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.144
ndr2 nodal-related 2 0.130
slc25a37 solute carrier family 25, member 37 0.129
lft1 lefty1 0.125
tgfb3 transforming growth factor, beta 3 0.122
myf6 myogenic factor 6 0.115
nkx2.7 NK2 transcription factor related 7 0.114
hand2 heart and neural crest derivatives expressed transcript 2 0.114
pard6gb par-6 partitioning defective 6 homolog gamma B (C. elegans) 0.111
ptf1a pancreas specific transcription factor, 1a 0.110
her7 hairy and enhancer of split related-7 0.109
spaw southpaw 0.108
dla deltaA 0.107
pcdh8 protocadherin 8 0.106
dzip1 DAZ interacting protein 1 0.100
dlc deltaC 0.098
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.097
hspa12b heat shock protein 12B 0.094
tp53 tumor protein p53 0.093
klf4 Kruppel-like factor 4 0.092
zgc:112211 zgc:112211 0.089
bhlhe41 basic helix-loop-helix family, member e41 0.089
tbx24 T-box 24 0.087
jun jun proto-oncogene 0.086
tnni1al troponin I, skeletal, slow like 0.084
ripply1 ripply1 0.084
ripply2 ripply2 0.084
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.084
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.083
pax2a paired box gene 2a 0.082
apobec2a apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a 0.080
smyd1b SET and MYND domain containing 1b 0.080
slc45a2 solute carrier family 45, member 2 0.079
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.078
bmp3 bone morphogenetic protein 3 0.078
gro1 groucho 1 0.076
prkci protein kinase C, iota 0.074
pdlim3b PDZ and LIM domain 3b 0.073
xirp1 xin actin-binding repeat containing 1 0.073
mespb mesoderm posterior b 0.073
limk1 LIM domain kinase 1 0.072
si:dkeyp-50f5.1 si:dkeyp-50f5.1 0.071
foxc1a forkhead box C1a 0.070
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.069
fgf3 fibroblast growth factor 3 0.069
pdlim5 PDZ and LIM domain 5 0.069
notch1a notch homolog 1a 0.069
myod1 myogenic differentiation 1 0.067
myf5 myogenic factor 5 0.066
lmna lamin A 0.066
tmem2 transmembrane protein 2 0.065
desma desmin a 0.065
vegfc vascular endothelial growth factor c 0.065
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.065
ctgf connective tissue growth factor 0.064
acvr1l activin A receptor, type I like 0.063
cxcr4a chemokine (C-X-C motif) receptor 4a 0.063
oep one-eyed pinhead 0.063
runx2b runt-related transcription factor 2b 0.060
shha sonic hedgehog a 0.060
bmpr1ab bone morphogenetic protein receptor, type 1ab 0.060
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
JAG1 jagged 1 1.000
TBX5 T-box 5 0.993
TAL1 T-cell acute lymphocytic leukemia 1 0.990
NOTCH1 notch 1 0.989
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.983
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.979
NOTCH3 notch 3 0.947
SMYD1 SET and MYND domain containing 1 0.902
BMP2 bone morphogenetic protein 2 0.859
FKBP1A FK506 binding protein 1A, 12kDa 0.840
TGFB1 transforming growth factor, beta 1 0.818
TGFB3 transforming growth factor, beta 3 0.570
ENG endoglin 0.539
HNF4A hepatocyte nuclear factor 4, alpha 0.523
GATA4 GATA binding protein 4 0.455
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.395
FSTL1 follistatin-like 1 0.388
GDF5 growth differentiation factor 5 0.266
PRKG1 protein kinase, cGMP-dependent, type I 0.220
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.190
ACVR1 activin A receptor, type I 0.188
PAX8 paired box 8 0.177
DLL1 delta-like 1 (Drosophila) 0.171
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.146
AKAP12 A kinase (PRKA) anchor protein 12 0.141
SPTB spectrin, beta, erythrocytic 0.130
RHAG Rh-associated glycoprotein 0.129
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.121
CTGF connective tissue growth factor 0.114
SMAD7 SMAD family member 7 0.109
CTBP2 C-terminal binding protein 2 0.103
JAG2 jagged 2 0.093
BMPR1A bone morphogenetic protein receptor, type IA 0.088
EHD1 EH-domain containing 1 0.082
GSK3B glycogen synthase kinase 3 beta 0.050
MAPK8 mitogen-activated protein kinase 8 0.049
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.048
XIAP X-linked inhibitor of apoptosis 0.048
NOTCH2NL notch 2 N-terminal like 0.047
MARCKSL1 MARCKS-like 1 0.046
THBS1 thrombospondin 1 0.042
TXNIP thioredoxin interacting protein 0.042
WNT3A wingless-type MMTV integration site family, member 3A 0.041
TGFBR1 transforming growth factor, beta receptor 1 0.038
PDGFC platelet derived growth factor C 0.038
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.037
LRRK2 leucine-rich repeat kinase 2 0.035
TBX1 T-box 1 0.034
SPTA1 spectrin, alpha, erythrocytic 1 (elliptocytosis 2) 0.033
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.031
TNNI1 troponin I type 1 (skeletal, slow) 0.031
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.031
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.029
PDE4DIP phosphodiesterase 4D interacting protein 0.028
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.027
HIC1 hypermethylated in cancer 1 0.026
GATA2 GATA binding protein 2 0.026
DBN1 drebrin 1 0.025
NRP1 neuropilin 1 0.025
SMAD1 SMAD family member 1 0.024
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.024
NKX6-1 NK6 homeobox 1 0.024
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.023
SOX18 SRY (sex determining region Y)-box 18 0.023
NOTCH2 notch 2 0.022
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.022
MYBPC2 myosin binding protein C, fast type 0.020
LBX1 ladybird homeobox 1 0.019
EGFL7 EGF-like-domain, multiple 7 0.019
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.019
TNNT3 troponin T type 3 (skeletal, fast) 0.019
ZFPM1 zinc finger protein, multitype 1 0.018
HOXD12 homeobox D12 0.018
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.018
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.017
BMP4 bone morphogenetic protein 4 0.017
CAV1 caveolin 1, caveolae protein, 22kDa 0.016
ANK1 ankyrin 1, erythrocytic 0.015
NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 0.015
HOXB13 homeobox B13 0.015
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.015
SIX2 SIX homeobox 2 0.014
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.014
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.014
PDX1 pancreatic and duodenal homeobox 1 0.014
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.014
TLX1 T-cell leukemia homeobox 1 0.014
TNNC1 troponin C type 1 (slow) 0.014
FERMT2 fermitin family member 2 0.013
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.012
CKM creatine kinase, muscle 0.012
HAND2 heart and neural crest derivatives expressed 2 0.012
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.012
ANTXR2 anthrax toxin receptor 2 0.012
VEGFA vascular endothelial growth factor A 0.012
BICD1 bicaudal D homolog 1 (Drosophila) 0.012
FZD1 frizzled homolog 1 (Drosophila) 0.012
VWF von Willebrand factor 0.012
DHH desert hedgehog 0.011
TTN titin 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Pitx2 paired-like homeodomain transcription factor 2 1.000
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 1.000
Shh sonic hedgehog 1.000
Gli3 GLI-Kruppel family member GLI3 0.999
Pax3 paired box gene 3 0.999
Fgfr2 fibroblast growth factor receptor 2 0.999
Foxc2 forkhead box C2 0.999
Fgf8 fibroblast growth factor 8 0.999
Tbx3 T-box 3 0.998
Nodal nodal 0.997
Gata4 GATA binding protein 4 0.996
Jag1 jagged 1 0.994
Hand1 heart and neural crest derivatives expressed transcript 1 0.992
Hand2 heart and neural crest derivatives expressed transcript 2 0.991
Fgfr1 fibroblast growth factor receptor 1 0.985
Tgfb2 transforming growth factor, beta 2 0.984
Foxc1 forkhead box C1 0.983
Pax2 paired box gene 2 0.978
Bmp4 bone morphogenetic protein 4 0.975
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.968
Otx2 orthodenticle homolog 2 (Drosophila) 0.966
Sox2 SRY-box containing gene 2 0.961
Notch1 Notch gene homolog 1 (Drosophila) 0.953
Pax6 paired box gene 6 0.951
Sox9 SRY-box containing gene 9 0.945
Tbx1 T-box 1 0.915
Smo smoothened homolog (Drosophila) 0.892
Meox2 mesenchyme homeobox 2 0.891
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.868
Wnt3a wingless-related MMTV integration site 3A 0.857
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.840
Efnb2 ephrin B2 0.828
Tcfap2a transcription factor AP-2, alpha 0.820
Gli2 GLI-Kruppel family member GLI2 0.805
Vangl2 vang-like 2 (van gogh, Drosophila) 0.804
Nog noggin 0.790
Rarg retinoic acid receptor, gamma 0.762
Chd7 chromodomain helicase DNA binding protein 7 0.752
Scn5a sodium channel, voltage-gated, type V, alpha 0.722
Smad6 MAD homolog 6 (Drosophila) 0.694
Tbx5 T-box 5 0.681
Emx2 empty spiracles homolog 2 (Drosophila) 0.672
Bmp7 bone morphogenetic protein 7 0.666
Pitx1 paired-like homeodomain transcription factor 1 0.666
Prrx2 paired related homeobox 2 0.607
Prrx1 paired related homeobox 1 0.572
Fgf10 fibroblast growth factor 10 0.571
Hoxd13 homeobox D13 0.567
Hoxa1 homeobox A1 0.566
Dll1 delta-like 1 (Drosophila) 0.560
Alx4 aristaless-like homeobox 4 0.546
Tbx2 T-box 2 0.546
Isl1 ISL1 transcription factor, LIM/homeodomain 0.541
She src homology 2 domain-containing transforming protein E 0.528
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.527
Col13a1 collagen, type XIII, alpha 1 0.505
Rxra retinoid X receptor alpha 0.491
Gata6 GATA binding protein 6 0.487
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.464
Zfpm2 zinc finger protein, multitype 2 0.456
Tbx15 T-box 15 0.450
Psen1 presenilin 1 0.449
Sox11 SRY-box containing gene 11 0.447
Sox7 SRY-box containing gene 7 0.445
Wt1 Wilms tumor 1 homolog 0.438
Msx1 homeobox, msh-like 1 0.436
Dll4 delta-like 4 (Drosophila) 0.422
Gja5 gap junction protein, alpha 5 0.405
Foxf1a forkhead box F1a 0.400
Flt4 FMS-like tyrosine kinase 4 0.397
Fgfr3 fibroblast growth factor receptor 3 0.391
Sall4 sal-like 4 (Drosophila) 0.382
Nos3 nitric oxide synthase 3, endothelial cell 0.354
Foxh1 forkhead box H1 0.343
Pax1 paired box gene 1 0.337
Ptprb protein tyrosine phosphatase, receptor type, B 0.326
Hoxa13 homeobox A13 0.320
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.313
Gbx2 gastrulation brain homeobox 2 0.310
Rarb retinoic acid receptor, beta 0.309
Eya1 eyes absent 1 homolog (Drosophila) 0.309
Zeb1 zinc finger E-box binding homeobox 1 0.298
Tal1 T-cell acute lymphocytic leukemia 1 0.286
Mesp1 mesoderm posterior 1 0.280
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.261
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.260
Wnt11 wingless-related MMTV integration site 11 0.247
Lhx1 LIM homeobox protein 1 0.247
Zic3 zinc finger protein of the cerebellum 3 0.241
Gdnf glial cell line derived neurotrophic factor 0.236
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.232
Gli1 GLI-Kruppel family member GLI1 0.224
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.211
Uncx UNC homeobox 0.211
Fgf18 fibroblast growth factor 18 0.211
Ntf3 neurotrophin 3 0.209
Gpc3 glypican 3 0.196
Hmx3 H6 homeobox 3 0.191
Alx3 aristaless-like homeobox 3 0.188
Sox17 SRY-box containing gene 17 0.185
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism