IMP

Process View

Homo sapiens

1 genes annotated in human

mature natural killer cell chemotaxis

The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mature natural killer cell chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mature natural killer cell chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
CCL4	chemokine (C-C motif) ligand 4	1.000	Human
CCL2	chemokine (C-C motif) ligand 2	1.000	Human
CCL5	chemokine (C-C motif) ligand 5	1.000	Human
CXCL9	chemokine (C-X-C motif) ligand 9	1.000
IL8	interleukin 8	1.000
IL1B	interleukin 1, beta	0.997
CXCL10	chemokine (C-X-C motif) ligand 10	0.996
CXCL2	chemokine (C-X-C motif) ligand 2	0.996
CCL8	chemokine (C-C motif) ligand 8	0.994	Human
IL6	interleukin 6 (interferon, beta 2)	0.987
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.986	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.985
CXCL3	chemokine (C-X-C motif) ligand 3	0.977
CCL22	chemokine (C-C motif) ligand 22	0.976	Human
DPP4	dipeptidyl-peptidase 4	0.975
CCR7	chemokine (C-C motif) receptor 7	0.969
CXCL11	chemokine (C-X-C motif) ligand 11	0.964
ICAM1	intercellular adhesion molecule 1	0.942
IDE	insulin-degrading enzyme	0.924
CCL13	chemokine (C-C motif) ligand 13	0.909	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.879
CCL19	chemokine (C-C motif) ligand 19	0.862	Human
CCL3	chemokine (C-C motif) ligand 3	0.843	Human
TNF	tumor necrosis factor	0.835
IFNG	interferon, gamma	0.824
CXCL13	chemokine (C-X-C motif) ligand 13	0.808
CD83	CD83 molecule	0.806
VCAM1	vascular cell adhesion molecule 1	0.798
TRAF1	TNF receptor-associated factor 1	0.763
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.742
CCL20	chemokine (C-C motif) ligand 20	0.734	Human
RGS1	regulator of G-protein signaling 1	0.724
CCR1	chemokine (C-C motif) receptor 1	0.703
IL7R	interleukin 7 receptor	0.687
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.659
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.634
IL10	interleukin 10	0.538
CCL7	chemokine (C-C motif) ligand 7	0.498	Human
SELE	selectin E	0.493
CCR4	chemokine (C-C motif) receptor 4	0.489
CXCL5	chemokine (C-X-C motif) ligand 5	0.486
IL2RB	interleukin 2 receptor, beta	0.462
BCL2A1	BCL2-related protein A1	0.454
UBD	ubiquitin D	0.375
CCL11	chemokine (C-C motif) ligand 11	0.373	Human
IL1RN	interleukin 1 receptor antagonist	0.351
BIRC3	baculoviral IAP repeat containing 3	0.334
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.325
SRGN	serglycin	0.304
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.279
CH25H	cholesterol 25-hydroxylase	0.270
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.207
FPR3	formyl peptide receptor 3	0.192
IL2RG	interleukin 2 receptor, gamma	0.185
CD69	CD69 molecule	0.177
CD40	CD40 molecule, TNF receptor superfamily member 5	0.175
DARC	Duffy blood group, chemokine receptor	0.166
IDO1	indoleamine 2,3-dioxygenase 1	0.161
LAMP3	lysosomal-associated membrane protein 3	0.158
IL10RA	interleukin 10 receptor, alpha	0.149
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.129
EBI3	Epstein-Barr virus induced 3	0.127
ADAMDEC1	ADAM-like, decysin 1	0.126
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.119
PLEK	pleckstrin	0.118
IRF4	interferon regulatory factor 4	0.105
STAT4	signal transducer and activator of transcription 4	0.104
SLAMF8	SLAM family member 8	0.096
SOD2	superoxide dismutase 2, mitochondrial	0.094
SLAMF7	SLAM family member 7	0.091
IL18RAP	interleukin 18 receptor accessory protein	0.088
IL1R2	interleukin 1 receptor, type II	0.088
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.084
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.077
IL21R	interleukin 21 receptor	0.075
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.072
IL2RA	interleukin 2 receptor, alpha	0.071
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.068
ARRB1	arrestin, beta 1	0.068
CXCR3	chemokine (C-X-C motif) receptor 3	0.067
XCL1	chemokine (C motif) ligand 1	0.064
CXCR6	chemokine (C-X-C motif) receptor 6	0.062
RGS16	regulator of G-protein signaling 16	0.060
CCL21	chemokine (C-C motif) ligand 21	0.056
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.049
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.048
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.047
MSC	musculin	0.047
CCR3	chemokine (C-C motif) receptor 3	0.047
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.047
XCL2	chemokine (C motif) ligand 2	0.046	Human
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.043
IL1A	interleukin 1, alpha	0.041
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.040
CCRL2	chemokine (C-C motif) receptor-like 2	0.039
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.036
GNLY	granulysin	0.035
IL15RA	interleukin 15 receptor, alpha	0.034
CSF1	colony stimulating factor 1 (macrophage)	0.034
SLAMF1	signaling lymphocytic activation molecule family member 1	0.033
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.033
CCL23	chemokine (C-C motif) ligand 23	0.032	Human
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.032
IL18R1	interleukin 18 receptor 1	0.032
CCL17	chemokine (C-C motif) ligand 17	0.031	Human
BATF	basic leucine zipper transcription factor, ATF-like	0.030
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.030
CD80	CD80 molecule	0.029
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.029
APOC1	apolipoprotein C-I	0.028
C3AR1	complement component 3a receptor 1	0.027
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.027
NKG7	natural killer cell group 7 sequence	0.027
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.026
CD163	CD163 molecule	0.026
TLR2	toll-like receptor 2	0.026
GPR109B	G protein-coupled receptor 109B	0.025
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.024
NNMT	nicotinamide N-methyltransferase	0.024
C5AR1	complement component 5a receptor 1	0.023
SOCS3	suppressor of cytokine signaling 3	0.023
CD40LG	CD40 ligand	0.022
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.022
C1R	complement component 1, r subcomponent	0.022
AQP9	aquaporin 9	0.022
SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.021
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.021
PTX3	pentraxin 3, long	0.020
TFEC	transcription factor EC	0.020
C2	complement component 2	0.019
INHBA	inhibin, beta A	0.019
RUNX3	runt-related transcription factor 3	0.019
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.019
PDPN	podoplanin	0.019
DNASE1L3	deoxyribonuclease I-like 3	0.019
LRRC32	leucine rich repeat containing 32	0.018
CCL1	chemokine (C-C motif) ligand 1	0.018	Human
IL13	interleukin 13	0.018
OSMR	oncostatin M receptor	0.018
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.017
LAG3	lymphocyte-activation gene 3	0.017
C3	complement component 3	0.017
ZC3H12A	zinc finger CCCH-type containing 12A	0.016
CD48	CD48 molecule	0.016
ICOS	inducible T-cell co-stimulator	0.015
CD209	CD209 molecule	0.015
IL7	interleukin 7	0.015
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.015
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.015
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.014
PI3	peptidase inhibitor 3, skin-derived	0.014
CXCR5	chemokine (C-X-C motif) receptor 5	0.014
G0S2	G0/G1switch 2	0.014
PRDM1	PR domain containing 1, with ZNF domain	0.014
DUSP2	dual specificity phosphatase 2	0.014
GPR183	G protein-coupled receptor 183	0.014
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.013
SCARF1	scavenger receptor class F, member 1	0.013
PLA1A	phospholipase A1 member A	0.013
CD160	CD160 molecule	0.013
NLRP3	NLR family, pyrin domain containing 3	0.013
DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	0.013
C1QB	complement component 1, q subcomponent, B chain	0.013
IL4	interleukin 4	0.013
PDCD1LG2	programmed cell death 1 ligand 2	0.013
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.013
IL4I1	interleukin 4 induced 1	0.013
MMP19	matrix metallopeptidase 19	0.013
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.013
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.013
CXCR4	chemokine (C-X-C motif) receptor 4	0.012
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.012
SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	0.012
TNIP3	TNFAIP3 interacting protein 3	0.012
TREM1	triggering receptor expressed on myeloid cells 1	0.012
CMKLR1	chemokine-like receptor 1	0.012
TYMP	thymidine phosphorylase	0.012
CHI3L2	chitinase 3-like 2	0.012
IL24	interleukin 24	0.012
CHIT1	chitinase 1 (chitotriosidase)	0.011
CCBP2	chemokine binding protein 2	0.011
IL32	interleukin 32	0.011
GPR84	G protein-coupled receptor 84	0.011
CXCL12	chemokine (C-X-C motif) ligand 12	0.011
CST7	cystatin F (leukocystatin)	0.011
CSF3	colony stimulating factor 3 (granulocyte)	0.011
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.010
EGR2	early growth response 2	0.010
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.010
CD86	CD86 molecule	0.010
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.010