IMP

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Homo sapiens

4 genes annotated in human

positive regulation of keratinocyte proliferation

Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of keratinocyte proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of keratinocyte proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000
FGF1	fibroblast growth factor 1 (acidic)	1.000	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	1.000
FGFR1	fibroblast growth factor receptor 1	1.000
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.999	Human
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.999
DSG2	desmoglein 2	0.999
JUP	junction plakoglobin	0.992
FGF10	fibroblast growth factor 10	0.989
PSEN1	presenilin 1	0.971
KRT5	keratin 5	0.941
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.930
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.843
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.802
FGFR3	fibroblast growth factor receptor 3	0.788
FGF2	fibroblast growth factor 2 (basic)	0.731	Human
FGF7	fibroblast growth factor 7	0.653
SATB2	SATB homeobox 2	0.595
CABLES1	Cdk5 and Abl enzyme substrate 1	0.534
GLIS2	GLIS family zinc finger 2	0.486
APC	adenomatous polyposis coli	0.474
DSP	desmoplakin	0.462
PLCG1	phospholipase C, gamma 1	0.455
TCF4	transcription factor 4	0.421
BTRC	beta-transducin repeat containing	0.411
FGF8	fibroblast growth factor 8 (androgen-induced)	0.392
KRT6C	keratin 6C	0.382
FRS2	fibroblast growth factor receptor substrate 2	0.295
EMD	emerin	0.287
CTNND1	catenin (cadherin-associated protein), delta 1	0.272
CTNNBIP1	catenin, beta interacting protein 1	0.235
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.233
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.230
KRT14	keratin 14	0.229
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.215	Human
PKP2	plakophilin 2	0.165
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.145
HNRNPCL1	heterogeneous nuclear ribonucleoprotein C-like 1	0.141
FGFBP1	fibroblast growth factor binding protein 1	0.136
PKP3	plakophilin 3	0.121
CTGF	connective tissue growth factor	0.119
CREBBP	CREB binding protein	0.103
S1PR5	sphingosine-1-phosphate receptor 5	0.102
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.093
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.091
EGFR	epidermal growth factor receptor	0.089
GPR87	G protein-coupled receptor 87	0.085
DSC3	desmocollin 3	0.080	Human
NOSTRIN	nitric oxide synthase trafficker	0.072
CRYAB	crystallin, alpha B	0.071
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.069
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.069
FERMT2	fermitin family member 2	0.069
DSG3	desmoglein 3	0.068
PTHLH	parathyroid hormone-like hormone	0.067
AR	androgen receptor	0.063
GSK3B	glycogen synthase kinase 3 beta	0.063
TGFA	transforming growth factor, alpha	0.060
KRT34	keratin 34	0.058
YAP1	Yes-associated protein 1	0.057
BNC1	basonuclin 1	0.055
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.054
PLEKHA7	pleckstrin homology domain containing, family A member 7	0.054
FGF3	fibroblast growth factor 3	0.048	Human
WNT1	wingless-type MMTV integration site family, member 1	0.046
INHBA	inhibin, beta A	0.046
AXIN1	axin 1	0.043
FGF4	fibroblast growth factor 4	0.043	Human
KRT6A	keratin 6A	0.042
DSG1	desmoglein 1	0.042
KRT1	keratin 1	0.041
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.040	Human
NIPSNAP3A	nipsnap homolog 3A (C. elegans)	0.038
PKP4	plakophilin 4	0.037
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.037
CLCA2	chloride channel accessory 2	0.036
SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.035
IRF6	interferon regulatory factor 6	0.034
G6PC	glucose-6-phosphatase, catalytic subunit	0.033
PVR	poliovirus receptor	0.033
PTK7	PTK7 protein tyrosine kinase 7	0.032
PCDH7	protocadherin 7	0.032
TACSTD2	tumor-associated calcium signal transducer 2	0.032
PTH	parathyroid hormone	0.032
CNTN1	contactin 1	0.031
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	0.031
MPZL2	myelin protein zero-like 2	0.030
FGF19	fibroblast growth factor 19	0.029
SLIT1	slit homolog 1 (Drosophila)	0.029
PRKCA	protein kinase C, alpha	0.028
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.028
PAX8	paired box 8	0.028
ITGB6	integrin, beta 6	0.027
FRMD5	FERM domain containing 5	0.027
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.027
LEF1	lymphoid enhancer-binding factor 1	0.026
COL17A1	collagen, type XVII, alpha 1	0.026
ESRP1	epithelial splicing regulatory protein 1	0.026
RGS4	regulator of G-protein signaling 4	0.026
KRT6B	keratin 6B	0.025
UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	0.025
FERMT1	fermitin family member 1	0.025
WNT3	wingless-type MMTV integration site family, member 3	0.025
FAT2	FAT tumor suppressor homolog 2 (Drosophila)	0.025
SPRR1B	small proline-rich protein 1B	0.025
GFAP	glial fibrillary acidic protein	0.025
COL4A6	collagen, type IV, alpha 6	0.025
TP63	tumor protein p63	0.024	Mouse
EGF	epidermal growth factor	0.024
S100A2	S100 calcium binding protein A2	0.024
ALOX12	arachidonate 12-lipoxygenase	0.024
NDRG1	N-myc downstream regulated 1	0.024
CXADR	coxsackie virus and adenovirus receptor	0.024
MAP1B	microtubule-associated protein 1B	0.023
LYPD3	LY6/PLAUR domain containing 3	0.023
FUS	fused in sarcoma	0.023
FST	follistatin	0.023
TRIM29	tripartite motif containing 29	0.023
MEGF11	multiple EGF-like-domains 11	0.022
CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.022
MAP1A	microtubule-associated protein 1A	0.022
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.022
GJB3	gap junction protein, beta 3, 31kDa	0.021
HMGA2	high mobility group AT-hook 2	0.021
FOXD3	forkhead box D3	0.021
TRIP6	thyroid hormone receptor interactor 6	0.021
TCF7	transcription factor 7 (T-cell specific, HMG-box)	0.020
NAV3	neuron navigator 3	0.020
CLDN1	claudin 1	0.020
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.020
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.020
APP	amyloid beta (A4) precursor protein	0.020
FGFR4	fibroblast growth factor receptor 4	0.020
JPH2	junctophilin 2	0.020
TP73	tumor protein p73	0.019
BDNF	brain-derived neurotrophic factor	0.019
FGF6	fibroblast growth factor 6	0.019	Human
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.019
VEGFC	vascular endothelial growth factor C	0.019
CTU2	cytosolic thiouridylase subunit 2 homolog (S. pombe)	0.019
FGF5	fibroblast growth factor 5	0.019	Human
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.019
ECEL1	endothelin converting enzyme-like 1	0.019
NKX2-1	NK2 homeobox 1	0.019
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.019
VSNL1	visinin-like 1	0.018
OSMR	oncostatin M receptor	0.018
EFCAB4B	EF-hand calcium binding domain 4B	0.018
GRHL2	grainyhead-like 2 (Drosophila)	0.018
PTPRG	protein tyrosine phosphatase, receptor type, G	0.018
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.018
SPINT2	serine peptidase inhibitor, Kunitz type, 2	0.018
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.018
TNS4	tensin 4	0.018
KAL1	Kallmann syndrome 1 sequence	0.018
CDH5	cadherin 5, type 2 (vascular endothelium)	0.017
T	T, brachyury homolog (mouse)	0.017
SFRP1	secreted frizzled-related protein 1	0.017
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.017
APC2	adenomatosis polyposis coli 2	0.017
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.017
TGFB2	transforming growth factor, beta 2	0.017
EPCAM	epithelial cell adhesion molecule	0.017
COL13A1	collagen, type XIII, alpha 1	0.017
HAS2	hyaluronan synthase 2	0.017	Rat
DOK5	docking protein 5	0.017
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.017
CALCA	calcitonin-related polypeptide alpha	0.017
CALB1	calbindin 1, 28kDa	0.017
RSPO3	R-spondin 3 homolog (Xenopus laevis)	0.017
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.017
NKX6-2	NK6 homeobox 2	0.016
BMP7	bone morphogenetic protein 7	0.016
IVL	involucrin	0.016
KLK10	kallikrein-related peptidase 10	0.016
MOS	v-mos Moloney murine sarcoma viral oncogene homolog	0.016
PSG9	pregnancy specific beta-1-glycoprotein 9	0.016
AMOTL1	angiomotin like 1	0.016
WNT9B	wingless-type MMTV integration site family, member 9B	0.016
C11orf41	chromosome 11 open reading frame 41	0.016
KRT75	keratin 75	0.016
SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.016
PERP	PERP, TP53 apoptosis effector	0.016
LRAT	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	0.016
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.016
FZD10	frizzled homolog 10 (Drosophila)	0.016
LAMC2	laminin, gamma 2	0.016
PDPN	podoplanin	0.016
SOX11	SRY (sex determining region Y)-box 11	0.016
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.015
HSPG2	heparan sulfate proteoglycan 2	0.015
NKD2	naked cuticle homolog 2 (Drosophila)	0.015
LPAR1	lysophosphatidic acid receptor 1	0.015
PDE10A	phosphodiesterase 10A	0.015
TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	0.015
KRT31	keratin 31	0.015
TJP1	tight junction protein 1 (zona occludens 1)	0.015
FOXN4	forkhead box N4	0.015
TFCP2L1	transcription factor CP2-like 1	0.015
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.015
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.015
WNT5A	wingless-type MMTV integration site family, member 5A	0.014
EPPK1	epiplakin 1	0.014
POU4F2	POU class 4 homeobox 2	0.014
DGKI	diacylglycerol kinase, iota	0.014
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.014
KCNK2	potassium channel, subfamily K, member 2	0.014
HSPA1B	heat shock 70kDa protein 1B	0.014
NOVA1	neuro-oncological ventral antigen 1	0.014
TBX5	T-box 5	0.014
PPL	periplakin	0.014
GBX1	gastrulation brain homeobox 1	0.014
PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	0.014
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.014
LENG8	leukocyte receptor cluster (LRC) member 8	0.014
SALL1	sal-like 1 (Drosophila)	0.013
NOS1	nitric oxide synthase 1 (neuronal)	0.013
D4S234E	DNA segment on chromosome 4 (unique) 234 expressed sequence	0.013
PGR	progesterone receptor	0.013
ZFHX4	zinc finger homeobox 4	0.013
PRKD1	protein kinase D1	0.013
PDLIM1	PDZ and LIM domain 1	0.013
BMP2	bone morphogenetic protein 2	0.013
GCGR	glucagon receptor	0.013
FLNB	filamin B, beta	0.013
ERAS	ES cell expressed Ras	0.013
ODAM	odontogenic, ameloblast asssociated	0.013
C15orf2	chromosome 15 open reading frame 2	0.013
B3GALT1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.013
SPRR3	small proline-rich protein 3	0.013
KRT8	keratin 8	0.013
OMP	olfactory marker protein	0.013
WWTR1	WW domain containing transcription regulator 1	0.013
SOX9	SRY (sex determining region Y)-box 9	0.013
GRB10	growth factor receptor-bound protein 10	0.013
PRDM12	PR domain containing 12	0.013
IRX4	iroquois homeobox 4	0.013
NPY1R	neuropeptide Y receptor Y1	0.013
CLDN4	claudin 4	0.012
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.012
SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	0.012
LBX1	ladybird homeobox 1	0.012
RHCG	Rh family, C glycoprotein	0.012
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.012
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.012
ANXA3	annexin A3	0.012
JPH3	junctophilin 3	0.012
GSC	goosecoid homeobox	0.012
HOXD1	homeobox D1	0.012
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.012
CDH13	cadherin 13, H-cadherin (heart)	0.012	Human
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.012
STRN3	striatin, calmodulin binding protein 3	0.012
VSX1	visual system homeobox 1	0.012
KRT9	keratin 9	0.012
DNMT3L	DNA (cytosine-5-)-methyltransferase 3-like	0.012
MAB21L1	mab-21-like 1 (C. elegans)	0.012
PTH2	parathyroid hormone 2	0.012
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.012
GDF3	growth differentiation factor 3	0.011
KCNJ14	potassium inwardly-rectifying channel, subfamily J, member 14	0.011
CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.011
NOL4	nucleolar protein 4	0.011
ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif, 3	0.011
NRG1	neuregulin 1	0.011
KLHL1	kelch-like 1 (Drosophila)	0.011
OXTR	oxytocin receptor	0.011
NCAM1	neural cell adhesion molecule 1	0.011
C1orf106	chromosome 1 open reading frame 106	0.011
CD24	CD24 molecule	0.011
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.011
PTPRR	protein tyrosine phosphatase, receptor type, R	0.011
CPA1	carboxypeptidase A1 (pancreatic)	0.011
SHB	Src homology 2 domain containing adaptor protein B	0.011
JRK	jerky homolog (mouse)	0.011
WNT7A	wingless-type MMTV integration site family, member 7A	0.011
EDAR	ectodysplasin A receptor	0.011
CLDN16	claudin 16	0.011
EDN2	endothelin 2	0.011
NLGN1	neuroligin 1	0.011
MSX2	msh homeobox 2	0.011
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.011
DTNA	dystrobrevin, alpha	0.011
KLF15	Kruppel-like factor 15	0.011
LPAR3	lysophosphatidic acid receptor 3	0.011
PTPRF	protein tyrosine phosphatase, receptor type, F	0.011
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.011
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.011
RGS20	regulator of G-protein signaling 20	0.011
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.011
BARHL1	BarH-like homeobox 1	0.011
ETV1	ets variant 1	0.011
GJB2	gap junction protein, beta 2, 26kDa	0.011
EPHA1	EPH receptor A1	0.011
EPHA3	EPH receptor A3	0.011
PTPRD	protein tyrosine phosphatase, receptor type, D	0.011
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.011
PRSS8	protease, serine, 8	0.011
ORM1	orosomucoid 1	0.011
IL11	interleukin 11	0.011
TNIK	TRAF2 and NCK interacting kinase	0.011
NEUROG2	neurogenin 2	0.011
ETV4	ets variant 4	0.011
FOXL1	forkhead box L1	0.010
LAMA3	laminin, alpha 3	0.010
LPPR4	lipid phosphate phosphatase-related protein type 4	0.010
NCSTN	nicastrin	0.010
NEUROG1	neurogenin 1	0.010
CTSL2	cathepsin L2	0.010
CHRND	cholinergic receptor, nicotinic, delta	0.010
CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	0.010
GIGYF1	GRB10 interacting GYF protein 1	0.010
FBN2	fibrillin 2	0.010
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.010
EPHA5	EPH receptor A5	0.010
FLRT3	fibronectin leucine rich transmembrane protein 3	0.010
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.010
MYO1A	myosin IA	0.010
THBS1	thrombospondin 1	0.010
LRP4	low density lipoprotein receptor-related protein 4	0.010
HOXD11	homeobox D11	0.010
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.010
FXYD3	FXYD domain containing ion transport regulator 3	0.010
KRT17	keratin 17	0.010
HAND1	heart and neural crest derivatives expressed 1	0.010
TTPA	tocopherol (alpha) transfer protein	0.010
DCBLD2	discoidin, CUB and LCCL domain containing 2	0.010
KDM5D	lysine (K)-specific demethylase 5D	0.010
ANGPT1	angiopoietin 1	0.010
FOXA1	forkhead box A1	0.010
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.010