IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

hypothalamus development

GO:0021854

The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hypothalamus development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hypothalamus development" (in gray)

Name	Description	Probability	Func Analog Organism
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.827
CRH	corticotropin releasing hormone	0.709	Rat
CRHR1	corticotropin releasing hormone receptor 1	0.689	Rat
PAX3	paired box 3	0.659
SOX10	SRY (sex determining region Y)-box 10	0.579
VEGFA	vascular endothelial growth factor A	0.573
RHOXF2	Rhox homeobox family, member 2	0.330
NUMBL	numb homolog (Drosophila)-like	0.314
BAK1	BCL2-antagonist/killer 1	0.269
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.246
QKI	quaking homolog, KH domain RNA binding (mouse)	0.218
MYLK2	myosin light chain kinase 2	0.168
BCL2L1	BCL2-like 1	0.144
DAXX	death-domain associated protein	0.142
ESR1	estrogen receptor 1	0.137
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.133
PPP5C	protein phosphatase 5, catalytic subunit	0.113
RNR2	l-rRNA	0.070
DMRTB1	DMRT-like family B with proline-rich C-terminal, 1	0.057
CELF3	CUGBP, Elav-like family member 3	0.056
BIK	BCL2-interacting killer (apoptosis-inducing)	0.047
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.046
TCF4	transcription factor 4	0.043
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.041
MYOD1	myogenic differentiation 1	0.040
BID	BH3 interacting domain death agonist	0.039
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.037
BAD	BCL2-associated agonist of cell death	0.035
MAX	MYC associated factor X	0.035
LENG8	leukocyte receptor cluster (LRC) member 8	0.034
MEOX2	mesenchyme homeobox 2	0.033
RBPMS	RNA binding protein with multiple splicing	0.031
MYBBP1A	MYB binding protein (P160) 1a	0.030
RUNX1	runt-related transcription factor 1	0.029
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.029
RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	0.028
ATXN1	ataxin 1	0.027
TGFB3	transforming growth factor, beta 3	0.027
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.025
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.025
STAT5A	signal transducer and activator of transcription 5A	0.023
SOX1	SRY (sex determining region Y)-box 1	0.023
RBM24	RNA binding motif protein 24	0.022
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.022
SOX11	SRY (sex determining region Y)-box 11	0.022
BIN1	bridging integrator 1	0.021
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.021
SPOP	speckle-type POZ protein	0.021
SP100	SP100 nuclear antigen	0.020
AP1S1	adaptor-related protein complex 1, sigma 1 subunit	0.020
GPR6	G protein-coupled receptor 6	0.018
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.018
C10orf46	chromosome 10 open reading frame 46	0.018
EP300	E1A binding protein p300	0.018
PAX7	paired box 7	0.018
NOVA2	neuro-oncological ventral antigen 2	0.017
VDAC1	voltage-dependent anion channel 1	0.017
FGF4	fibroblast growth factor 4	0.017
PGF	placental growth factor	0.016
GLIS2	GLIS family zinc finger 2	0.016
POU4F1	POU class 4 homeobox 1	0.016
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.016
POU3F3	POU class 3 homeobox 3	0.016
HIPK2	homeodomain interacting protein kinase 2	0.015
FBXW8	F-box and WD repeat domain containing 8	0.015
DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	0.015
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.015
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.015
PCBP4	poly(rC) binding protein 4	0.015
HES2	hairy and enhancer of split 2 (Drosophila)	0.014
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.014
BHLHE23	basic helix-loop-helix family, member e23	0.014
MCRS1	microspherule protein 1	0.014
EMX1	empty spiracles homeobox 1	0.014
PABPC5	poly(A) binding protein, cytoplasmic 5	0.013
HOXB7	homeobox B7	0.013
PRMT2	protein arginine methyltransferase 2	0.013
RHO	rhodopsin	0.013
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.013
PAX6	paired box 6	0.013
PRRX1	paired related homeobox 1	0.013
CELF4	CUGBP, Elav-like family member 4	0.013
KCNK12	potassium channel, subfamily K, member 12	0.012
AKAP13	A kinase (PRKA) anchor protein 13	0.012
INSL3	insulin-like 3 (Leydig cell)	0.012
PELO	pelota homolog (Drosophila)	0.012
PAX5	paired box 5	0.012
FOXN4	forkhead box N4	0.012
TAL1	T-cell acute lymphocytic leukemia 1	0.012
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.012
ALX3	ALX homeobox 3	0.012
SIX6	SIX homeobox 6	0.012
AR	androgen receptor	0.012
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.012
GSX2	GS homeobox 2	0.012
C14orf43	chromosome 14 open reading frame 43	0.012
CLDN7	claudin 7	0.012
BNC2	basonuclin 2	0.012
ACTN2	actinin, alpha 2	0.012
MEF2C	myocyte enhancer factor 2C	0.012
HOXC8	homeobox C8	0.012
FEZ2	fasciculation and elongation protein zeta 2 (zygin II)	0.012
SOX21	SRY (sex determining region Y)-box 21	0.012
OPRD1	opioid receptor, delta 1	0.012
LBX1	ladybird homeobox 1	0.011
FBXW7	F-box and WD repeat domain containing 7	0.011
RUNX2	runt-related transcription factor 2	0.011
VSX1	visual system homeobox 1	0.011
SCN2B	sodium channel, voltage-gated, type II, beta	0.011
FOSL1	FOS-like antigen 1	0.011
FOXD3	forkhead box D3	0.011
HOXD13	homeobox D13	0.011
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.011
BECN1	beclin 1, autophagy related	0.011
NPAS4	neuronal PAS domain protein 4	0.011
TLX2	T-cell leukemia homeobox 2	0.011
GJD2	gap junction protein, delta 2, 36kDa	0.011
CDX2	caudal type homeobox 2	0.011
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.011
NKX2-1	NK2 homeobox 1	0.011
AMELX	amelogenin, X-linked	0.011
NEUROG3	neurogenin 3	0.011
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.011
SIX2	SIX homeobox 2	0.011
TBX1	T-box 1	0.010
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.010
EPAS1	endothelial PAS domain protein 1	0.010
POU3F1	POU class 3 homeobox 1	0.010
OTX2	orthodenticle homeobox 2	0.010
DPYSL2	dihydropyrimidinase-like 2	0.010
POU4F3	POU class 4 homeobox 3	0.010
KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9	0.010
RBM11	RNA binding motif protein 11	0.010
FOXG1	forkhead box G1	0.010
PDX1	pancreatic and duodenal homeobox 1	0.010
DRD2	dopamine receptor D2	0.010
MITF	microphthalmia-associated transcription factor	0.010
SLC32A1	solute carrier family 32 (GABA vesicular transporter), member 1	0.010
HOXB8	homeobox B8	0.010
KCNH1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.010
C1QL1	complement component 1, q subcomponent-like 1	0.010
BBC3	BCL2 binding component 3	0.010
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.010