IMP
Process View
cyclin catabolic process
The chemical reactions and pathways resulting in the breakdown of cyclins, proteins whose levels in a cell varies markedly during the cell cycle, and which play key roles in regulating cell cycle phase transitions.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cyclin catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 1.000 | Yeast Fly | |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.993 | Fly | |
| CUL1 | cullin 1 | 0.974 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.968 | ||
| CCNB1 | cyclin B1 | 0.963 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.875 | ||
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.824 | Fly | |
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.816 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.756 | ||
| COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.700 | ||
| CCNA2 | cyclin A2 | 0.669 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.624 | ||
| CCNB2 | cyclin B2 | 0.604 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.433 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.358 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.358 | ||
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.333 | Fly | |
| COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.300 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.265 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.248 | ||
| CUL2 | cullin 2 | 0.239 | Worm | |
| PLK1 | polo-like kinase 1 | 0.238 | ||
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.168 | Fly | |
| FOXM1 | forkhead box M1 | 0.163 | ||
| COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.145 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.142 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.125 | ||
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.124 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.097 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.092 | ||
| COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.083 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.065 | ||
| BIRC5 | baculoviral IAP repeat containing 5 | 0.060 | ||
| GFER | growth factor, augmenter of liver regeneration | 0.057 | ||
| SIRT2 | sirtuin 2 | 0.052 | ||
| CDK1 | cyclin-dependent kinase 1 | 0.044 | ||
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 0.043 | ||
| CUL4A | cullin 4A | 0.041 | ||
| COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.038 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.038 | Yeast | |
| CLSPN | claspin | 0.035 | ||
| MAK | male germ cell-associated kinase | 0.032 | ||
| AURKB | aurora kinase B | 0.032 | ||
| COPS7A | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) | 0.030 | ||
| CUL5 | cullin 5 | 0.028 | ||
| ZYG11B | zyg-11 homolog B (C. elegans) | 0.025 | ||
| LRR1 | leucine rich repeat protein 1 | 0.023 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.022 | ||
| CUL4B | cullin 4B | 0.021 | ||
| SNX9 | sorting nexin 9 | 0.021 | ||
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.021 | ||
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.020 | ||
| C8orf40 | chromosome 8 open reading frame 40 | 0.019 | ||
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.018 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.017 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.016 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.016 | ||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.015 | ||
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.015 | ||
| TXN | thioredoxin | 0.014 | ||
| ANAPC2 | anaphase promoting complex subunit 2 | 0.014 | ||
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.013 | ||
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.012 | ||
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.011 | ||
| JAG2 | jagged 2 | 0.011 | ||
| MYBL2 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | 0.010 |