IMP

Process View

Homo sapiens

11 genes annotated in human

receptor catabolic process

The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "receptor catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "receptor catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD4	SMAD family member 4	0.995
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.993	Human
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.943	Human
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.890	Human
ZFYVE9	zinc finger, FYVE domain containing 9	0.876
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.808
HP	haptoglobin	0.704
GPRASP1	G protein-coupled receptor associated sorting protein 1	0.656
CXXC5	CXXC finger protein 5	0.451
ANKRD13A	ankyrin repeat domain 13A	0.447
ARMCX3	armadillo repeat containing, X-linked 3	0.360
LDLR	low density lipoprotein receptor	0.329
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.290
ALB	albumin	0.287
TGFBR1	transforming growth factor, beta receptor 1	0.280
APOC1	apolipoprotein C-I	0.275
ENG	endoglin	0.262
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.245
SMAD5	SMAD family member 5	0.241
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.177
LCAT	lecithin-cholesterol acyltransferase	0.176
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.165
DTX1	deltex homolog 1 (Drosophila)	0.146
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.126
SMAD6	SMAD family member 6	0.121
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.119
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.115
SMAD1	SMAD family member 1	0.089
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.088
TCEAL4	transcription elongation factor A (SII)-like 4	0.087
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.073
A2M	alpha-2-macroglobulin	0.072
SMAD7	SMAD family member 7	0.072
ARMCX2	armadillo repeat containing, X-linked 2	0.068	Human
SOX7	SRY (sex determining region Y)-box 7	0.061
FBXL15	F-box and leucine-rich repeat protein 15	0.061
FSTL1	follistatin-like 1	0.059
SKIL	SKI-like oncogene	0.056
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.053
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.051
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.051
CABLES1	Cdk5 and Abl enzyme substrate 1	0.049
SNX18	sorting nexin 18	0.045
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.043
RHOA	ras homolog gene family, member A	0.041
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.041
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.039
EEA1	early endosome antigen 1	0.037
TGFB3	transforming growth factor, beta 3	0.036
ADARB1	adenosine deaminase, RNA-specific, B1	0.035
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.033	Human
YAP1	Yes-associated protein 1	0.032
ARMCX1	armadillo repeat containing, X-linked 1	0.031	Human
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.031
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.030
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.029
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.027
EPAS1	endothelial PAS domain protein 1	0.026
KLF5	Kruppel-like factor 5 (intestinal)	0.024
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.023
STAMBP	STAM binding protein	0.023
PLTP	phospholipid transfer protein	0.023
PPIL4	peptidylprolyl isomerase (cyclophilin)-like 4	0.022
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.021
APOC3	apolipoprotein C-III	0.021
RNFT1	ring finger protein, transmembrane 1	0.021
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.020	Human
ALAS1	aminolevulinate, delta-, synthase 1	0.020
PDCD6IP	programmed cell death 6 interacting protein	0.020
RASAL2	RAS protein activator like 2	0.019
CAPNS1	calpain, small subunit 1	0.018
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.018
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.018
DLG1	discs, large homolog 1 (Drosophila)	0.017
CCDC127	coiled-coil domain containing 127	0.016
USP17	ubiquitin specific peptidase 17	0.016
APP	amyloid beta (A4) precursor protein	0.015
MKL2	MKL/myocardin-like 2	0.015
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.015
CEP55	centrosomal protein 55kDa	0.014
FOXD3	forkhead box D3	0.014
SNX33	sorting nexin 33	0.013
POLI	polymerase (DNA directed) iota	0.013
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.012
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.012
CSNK1D	casein kinase 1, delta	0.012
PIK3C3	phosphoinositide-3-kinase, class 3	0.012
TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	0.012
RNF168	ring finger protein 168	0.011
GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	0.011
TTR	transthyretin	0.011
APOC2	apolipoprotein C-II	0.011
DOCK9	dedicator of cytokinesis 9	0.011
WNK1	WNK lysine deficient protein kinase 1	0.011
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.010
CHMP4B	chromatin modifying protein 4B	0.010
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.010