IMP

Process View

Homo sapiens

23 genes annotated in human

membrane repolarization

The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the resting potential. For example, the repolarization during an action potential is in the direction from the positive membrane potential towards the negative resting potential.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "membrane repolarization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "membrane repolarization" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	1.000	Human
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	1.000	Human
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	1.000	Human
KCNIP2	Kv channel interacting protein 2	0.993
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.986	Human
DLG4	discs, large homolog 4 (Drosophila)	0.975
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.934
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.911
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.886
SCN5A	sodium channel, voltage-gated, type V, alpha subunit	0.877
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.770	Human
LIN7B	lin-7 homolog B (C. elegans)	0.761
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.746
KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2	0.714	Human
ACTN2	actinin, alpha 2	0.679
CABP1	calcium binding protein 1	0.618
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.618
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.588	Human
SNTG2	syntrophin, gamma 2	0.532	Human
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.487
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.391	Human
MAPK12	mitogen-activated protein kinase 12	0.359
DMD	dystrophin	0.341
TJP1	tight junction protein 1 (zona occludens 1)	0.296
CD177	CD177 molecule	0.227
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.225
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.218
DTNA	dystrobrevin, alpha	0.206
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.186
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.169
SPTB	spectrin, beta, erythrocytic	0.167
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.159	Human
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.152	Human
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.133
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.126
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.123
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.122
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.117
RHAG	Rh-associated glycoprotein	0.111
CLCN3	chloride channel 3	0.094
RYR2	ryanodine receptor 2 (cardiac)	0.090
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.089	Human
KCNIP1	Kv channel interacting protein 1	0.081	Human
RHOA	ras homolog gene family, member A	0.073
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.073	Human
CCKBR	cholecystokinin B receptor	0.072
KCNH1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.069	Human
ZFYVE9	zinc finger, FYVE domain containing 9	0.068
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.065	Human
ANKRD13A	ankyrin repeat domain 13A	0.061
FBXL15	F-box and leucine-rich repeat protein 15	0.060
RNF11	ring finger protein 11	0.056
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.054
NLGN1	neuroligin 1	0.053
SMAD5	SMAD family member 5	0.050
TTN	titin	0.049
DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.049
KCNB2	potassium voltage-gated channel, Shab-related subfamily, member 2	0.049	Human
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.044
KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1	0.044
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.042
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.040
BAI1	brain-specific angiogenesis inhibitor 1	0.039
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.038	Human
SMAD7	SMAD family member 7	0.036
MYOZ1	myozenin 1	0.035
DPP6	dipeptidyl-peptidase 6	0.035
MARK2	MAP/microtubule affinity-regulating kinase 2	0.035
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.035
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.034
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.033
UTRN	utrophin	0.031
KCNJ10	potassium inwardly-rectifying channel, subfamily J, member 10	0.031	Human
KCNG3	potassium voltage-gated channel, subfamily G, member 3	0.031	Human
SRRM4	serine/arginine repetitive matrix 4	0.029
ARHGAP22	Rho GTPase activating protein 22	0.029
FRS2	fibroblast growth factor receptor substrate 2	0.029
ACTL6B	actin-like 6B	0.029
KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9	0.029	Human
FOXD3	forkhead box D3	0.026
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.025
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.025
DLG2	discs, large homolog 2 (Drosophila)	0.025
KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.025	Human
ACHE	acetylcholinesterase	0.023
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.023
EHD1	EH-domain containing 1	0.023
ADRA1D	adrenergic, alpha-1D-, receptor	0.023
CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1	0.022
SMAD1	SMAD family member 1	0.022
GRIK1	glutamate receptor, ionotropic, kainate 1	0.022
SLITRK3	SLIT and NTRK-like family, member 3	0.022
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.022	Human
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.022
SEZ6L	seizure related 6 homolog (mouse)-like	0.021
P2RX6	purinergic receptor P2X, ligand-gated ion channel, 6	0.021
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.021
SCN3B	sodium channel, voltage-gated, type III, beta	0.021
SFN	stratifin	0.021	Human
CADM3	cell adhesion molecule 3	0.021
NPY	neuropeptide Y	0.021
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.020
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.020
HRH3	histamine receptor H3	0.020
ARRDC3	arrestin domain containing 3	0.020
GRM7	glutamate receptor, metabotropic 7	0.020
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.019
PTPRN	protein tyrosine phosphatase, receptor type, N	0.019
GRIA3	glutamate receptor, ionotrophic, AMPA 3	0.019
POU5F1	POU class 5 homeobox 1	0.019
TUBB2B	tubulin, beta 2B	0.019
BSN	bassoon (presynaptic cytomatrix protein)	0.019
USP2	ubiquitin specific peptidase 2	0.019
SMAD4	SMAD family member 4	0.018
RIMS1	regulating synaptic membrane exocytosis 1	0.018
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.018
RIMBP2	RIMS binding protein 2	0.018
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.018
SYN2	synapsin II	0.018
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.018
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.018	Human
ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.018
RGS6	regulator of G-protein signaling 6	0.017
PRKCG	protein kinase C, gamma	0.017
VSTM2A	V-set and transmembrane domain containing 2A	0.017
KCNJ16	potassium inwardly-rectifying channel, subfamily J, member 16	0.017	Human
UNC13A	unc-13 homolog A (C. elegans)	0.017
ING1	inhibitor of growth family, member 1	0.017
ADAM11	ADAM metallopeptidase domain 11	0.016
GRIK5	glutamate receptor, ionotropic, kainate 5	0.016
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.016
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.016
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.016
NELL1	NEL-like 1 (chicken)	0.016
CNTN2	contactin 2 (axonal)	0.015
NECAB2	N-terminal EF-hand calcium binding protein 2	0.015
CACNB4	calcium channel, voltage-dependent, beta 4 subunit	0.015
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.015
KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.015	Human
DTNB	dystrobrevin, beta	0.015
MAP1A	microtubule-associated protein 1A	0.015
NOS1	nitric oxide synthase 1 (neuronal)	0.015
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.015
KCNIP4	Kv channel interacting protein 4	0.015	Human
CPLX2	complexin 2	0.014
SCN2B	sodium channel, voltage-gated, type II, beta	0.014	Human
CXXC5	CXXC finger protein 5	0.014
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.014
DDN	dendrin	0.014
HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	0.014
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.014	Human
ADCYAP1R1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.014
KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.014
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.014
GRIK4	glutamate receptor, ionotropic, kainate 4	0.014
KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6	0.014	Human
PRDM8	PR domain containing 8	0.014
KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.013
WSCD1	WSC domain containing 1	0.013
SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.013
GRM5	glutamate receptor, metabotropic 5	0.013
CDH8	cadherin 8, type 2	0.013
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.013	Human
TRPM3	transient receptor potential cation channel, subfamily M, member 3	0.013
GRM3	glutamate receptor, metabotropic 3	0.013
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.013
GRM1	glutamate receptor, metabotropic 1	0.013
OPRM1	opioid receptor, mu 1	0.013
BZRAP1	benzodiazapine receptor (peripheral) associated protein 1	0.013
NRXN1	neurexin 1	0.012
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.012
WNK1	WNK lysine deficient protein kinase 1	0.012
CCDC48	coiled-coil domain containing 48	0.012
TMEM59L	transmembrane protein 59-like	0.012
PGAM2	phosphoglycerate mutase 2 (muscle)	0.012
MAPK4	mitogen-activated protein kinase 4	0.012
FXYD7	FXYD domain containing ion transport regulator 7	0.012
KIF1A	kinesin family member 1A	0.012
SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.012
PDZK1	PDZ domain containing 1	0.012
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.012
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.012	Human
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
BCAN	brevican	0.012
SLC4A3	solute carrier family 4, anion exchanger, member 3	0.012
FAM5B	family with sequence similarity 5, member B	0.012
ACTN3	actinin, alpha 3	0.012
NDRG2	NDRG family member 2	0.012
SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	0.012
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.011	Human
RNF168	ring finger protein 168	0.011
GRIK3	glutamate receptor, ionotropic, kainate 3	0.011
SNCB	synuclein, beta	0.011
GLRA1	glycine receptor, alpha 1	0.011
KCNJ3	potassium inwardly-rectifying channel, subfamily J, member 3	0.011
LDB3	LIM domain binding 3	0.011
NCAN	neurocan	0.011
MEGF8	multiple EGF-like-domains 8	0.011
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.011
SOX7	SRY (sex determining region Y)-box 7	0.011
GHSR	growth hormone secretagogue receptor	0.011
TMEM130	transmembrane protein 130	0.011
CACNG2	calcium channel, voltage-dependent, gamma subunit 2	0.011
LPHN1	latrophilin 1	0.011
KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	0.011	Human
JPH3	junctophilin 3	0.011
ESRRB	estrogen-related receptor beta	0.011
RIT2	Ras-like without CAAX 2	0.011
CRIPT	cysteine-rich PDZ-binding protein	0.011
OPRK1	opioid receptor, kappa 1	0.011
FXYD1	FXYD domain containing ion transport regulator 1	0.011
CACNG3	calcium channel, voltage-dependent, gamma subunit 3	0.011
KCNH6	potassium voltage-gated channel, subfamily H (eag-related), member 6	0.011	Human
LRTM2	leucine-rich repeats and transmembrane domains 2	0.010
CNTN6	contactin 6	0.010
FBXO40	F-box protein 40	0.010
GFAP	glial fibrillary acidic protein	0.010
ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	0.010
KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	0.010
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.010
HPCA	hippocalcin	0.010
BAD	BCL2-associated agonist of cell death	0.010
ADCY8	adenylate cyclase 8 (brain)	0.010
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	0.010
SCN2A	sodium channel, voltage-gated, type II, alpha subunit	0.010
CA10	carbonic anhydrase X	0.010
TTYH1	tweety homolog 1 (Drosophila)	0.010
TACR1	tachykinin receptor 1	0.010
HPCAL4	hippocalcin like 4	0.010