IMP

Process View

Homo sapiens

2 genes annotated in human

Multi-species View

cd4 positive alpha beta t cell proliferation

GO:0035739

The expansion of a CD4-positive, alpha-beta T cell population by cell division.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cd4 positive alpha beta t cell proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cd4 positive alpha beta t cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
CCL4	chemokine (C-C motif) ligand 4	0.996	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.993
CCL5	chemokine (C-C motif) ligand 5	0.991	Human
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.975	Human
CCL2	chemokine (C-C motif) ligand 2	0.956	Human
DPP4	dipeptidyl-peptidase 4	0.941
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.891
IL1B	interleukin 1, beta	0.863
CCL8	chemokine (C-C motif) ligand 8	0.862	Human
IL8	interleukin 8	0.859
CCL19	chemokine (C-C motif) ligand 19	0.821	Human
CCL13	chemokine (C-C motif) ligand 13	0.788	Human
IDE	insulin-degrading enzyme	0.760
CXCL10	chemokine (C-X-C motif) ligand 10	0.705
IL6	interleukin 6 (interferon, beta 2)	0.668
CXCL11	chemokine (C-X-C motif) ligand 11	0.654
CCR7	chemokine (C-C motif) receptor 7	0.648
CXCL2	chemokine (C-X-C motif) ligand 2	0.595
CCL22	chemokine (C-C motif) ligand 22	0.585	Human
TRAF1	TNF receptor-associated factor 1	0.497
IFNG	interferon, gamma	0.478
CXCL13	chemokine (C-X-C motif) ligand 13	0.439
CXCL3	chemokine (C-X-C motif) ligand 3	0.402
VCAM1	vascular cell adhesion molecule 1	0.397
CCR4	chemokine (C-C motif) receptor 4	0.371
CCR1	chemokine (C-C motif) receptor 1	0.317
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.315
RGS1	regulator of G-protein signaling 1	0.300
CCL7	chemokine (C-C motif) ligand 7	0.287	Human
IL2RB	interleukin 2 receptor, beta	0.273
CD83	CD83 molecule	0.259
IL7R	interleukin 7 receptor	0.249
CCL11	chemokine (C-C motif) ligand 11	0.224	Human
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.219
IL10	interleukin 10	0.198
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.193
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.193
NKG7	natural killer cell group 7 sequence	0.164
CPD	carboxypeptidase D	0.147
CXCL5	chemokine (C-X-C motif) ligand 5	0.122
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.121
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.116
TNF	tumor necrosis factor	0.108
CCL20	chemokine (C-C motif) ligand 20	0.107	Human
UBD	ubiquitin D	0.106
IL10RA	interleukin 10 receptor, alpha	0.105
CCL3	chemokine (C-C motif) ligand 3	0.104	Human
CH25H	cholesterol 25-hydroxylase	0.098
DARC	Duffy blood group, chemokine receptor	0.085
IL2RG	interleukin 2 receptor, gamma	0.084
CD69	CD69 molecule	0.080
ADAMDEC1	ADAM-like, decysin 1	0.077
SELE	selectin E	0.076
LAMP3	lysosomal-associated membrane protein 3	0.076
STAT4	signal transducer and activator of transcription 4	0.074
IL1RN	interleukin 1 receptor antagonist	0.072
BCL2A1	BCL2-related protein A1	0.071
EBI3	Epstein-Barr virus induced 3	0.071
FPR3	formyl peptide receptor 3	0.071
ICAM1	intercellular adhesion molecule 1	0.069
CCL21	chemokine (C-C motif) ligand 21	0.068
CCL17	chemokine (C-C motif) ligand 17	0.067	Human
GNLY	granulysin	0.067
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.064
IDO1	indoleamine 2,3-dioxygenase 1	0.057
IL18RAP	interleukin 18 receptor accessory protein	0.055
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.054
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.053
IL1R2	interleukin 1 receptor, type II	0.051
PI3	peptidase inhibitor 3, skin-derived	0.046
SLAMF7	SLAM family member 7	0.045
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.042
SRGN	serglycin	0.041
SLAMF8	SLAM family member 8	0.041
CCR3	chemokine (C-C motif) receptor 3	0.041
CD160	CD160 molecule	0.041
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.039
SLAMF1	signaling lymphocytic activation molecule family member 1	0.039
CD40	CD40 molecule, TNF receptor superfamily member 5	0.037
CCL23	chemokine (C-C motif) ligand 23	0.036	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.035
IL32	interleukin 32	0.035
INHBA	inhibin, beta A	0.035
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.035
IL1A	interleukin 1, alpha	0.034
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.033
C1QB	complement component 1, q subcomponent, B chain	0.033
CXCR3	chemokine (C-X-C motif) receptor 3	0.032
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.032
PLEK	pleckstrin	0.031
MSC	musculin	0.031
ARRB1	arrestin, beta 1	0.029
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.029
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.028
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.027
SOD2	superoxide dismutase 2, mitochondrial	0.027
IL21R	interleukin 21 receptor	0.026
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.026
CST7	cystatin F (leukocystatin)	0.025
BATF	basic leucine zipper transcription factor, ATF-like	0.025
IL18R1	interleukin 18 receptor 1	0.024
RGS16	regulator of G-protein signaling 16	0.024
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.024
GZMK	granzyme K (granzyme 3; tryptase II)	0.023
CCRL2	chemokine (C-C motif) receptor-like 2	0.023
NNMT	nicotinamide N-methyltransferase	0.023
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.023
IRF4	interferon regulatory factor 4	0.022
DNASE1L3	deoxyribonuclease I-like 3	0.022
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.021
C3AR1	complement component 3a receptor 1	0.020
CD1B	CD1b molecule	0.020
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.020
C2	complement component 2	0.020
C5AR1	complement component 5a receptor 1	0.019
AQP9	aquaporin 9	0.019
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.019
LGALS9	lectin, galactoside-binding, soluble, 9	0.019
GPR109B	G protein-coupled receptor 109B	0.018
TM7SF4	transmembrane 7 superfamily member 4	0.018
ICOS	inducible T-cell co-stimulator	0.018
APOC1	apolipoprotein C-I	0.018
PDPN	podoplanin	0.018
CCBP2	chemokine binding protein 2	0.017
CD163	CD163 molecule	0.017
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.017
CLEC10A	C-type lectin domain family 10, member A	0.017
HLA-DQB2	major histocompatibility complex, class II, DQ beta 2	0.017
SAT1	spermidine/spermine N1-acetyltransferase 1	0.017
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.017
CCL1	chemokine (C-C motif) ligand 1	0.017	Human
SCARF1	scavenger receptor class F, member 1	0.017
CD209	CD209 molecule	0.017
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.016
CREM	cAMP responsive element modulator	0.016
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.016
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.016
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.016
CD40LG	CD40 ligand	0.016
LAG3	lymphocyte-activation gene 3	0.015
CD80	CD80 molecule	0.015
CSF1	colony stimulating factor 1 (macrophage)	0.015
DPT	dermatopontin	0.015
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.015
IL13	interleukin 13	0.014
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.014
KYNU	kynureninase	0.014
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.014
IGL@	immunoglobulin lambda locus	0.014
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.014
CD48	CD48 molecule	0.014
PGRMC1	progesterone receptor membrane component 1	0.014
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.014
IL4I1	interleukin 4 induced 1	0.014
IL7	interleukin 7	0.014
LRRC32	leucine rich repeat containing 32	0.014
RUNX3	runt-related transcription factor 3	0.013
GPR171	G protein-coupled receptor 171	0.013
IL11	interleukin 11	0.013
ZC3H12A	zinc finger CCCH-type containing 12A	0.013
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.013
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.013
SNAP23	synaptosomal-associated protein, 23kDa	0.013
PICALM	phosphatidylinositol binding clathrin assembly protein	0.013
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.012
GPR84	G protein-coupled receptor 84	0.012
C1S	complement component 1, s subcomponent	0.012
XCL2	chemokine (C motif) ligand 2	0.012	Human
TNIP3	TNFAIP3 interacting protein 3	0.012
RGL1	ral guanine nucleotide dissociation stimulator-like 1	0.012
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.012
CTSW	cathepsin W	0.012
IL1F5	interleukin 1 family, member 5 (delta)	0.012
CXCR6	chemokine (C-X-C motif) receptor 6	0.012
CXCR4	chemokine (C-X-C motif) receptor 4	0.012
CXCL12	chemokine (C-X-C motif) ligand 12	0.012
IL4	interleukin 4	0.012
PLAUR	plasminogen activator, urokinase receptor	0.012
IL12RB1	interleukin 12 receptor, beta 1	0.011
IL1F9	interleukin 1 family, member 9	0.011
MOXD1	monooxygenase, DBH-like 1	0.011
CHI3L2	chitinase 3-like 2	0.011
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.011
TREM1	triggering receptor expressed on myeloid cells 1	0.011
TM9SF2	transmembrane 9 superfamily member 2	0.011
TBX21	T-box 21	0.011
TARP	TCR gamma alternate reading frame protein	0.011
PLA1A	phospholipase A1 member A	0.011
APCS	amyloid P component, serum	0.011
PLA2G2D	phospholipase A2, group IID	0.011
CHIT1	chitinase 1 (chitotriosidase)	0.011
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.011
OSMR	oncostatin M receptor	0.010
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.010
CSF3	colony stimulating factor 3 (granulocyte)	0.010
CD1C	CD1c molecule	0.010
IL1R1	interleukin 1 receptor, type I	0.010
XCL1	chemokine (C motif) ligand 1	0.010
NLRP3	NLR family, pyrin domain containing 3	0.010
CD226	CD226 molecule	0.010
IL13RA1	interleukin 13 receptor, alpha 1	0.010
EGFL6	EGF-like-domain, multiple 6	0.010
CD9	CD9 molecule	0.010