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Homo sapiens

17 genes annotated in human

keratinocyte proliferation

The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "keratinocyte proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "keratinocyte proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.998
FGFR2	fibroblast growth factor receptor 2	0.996
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.970	Human
KRT15	keratin 15	0.896
TP63	tumor protein p63	0.729	Mouse
CTNND1	catenin (cadherin-associated protein), delta 1	0.699
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.678
KRT17	keratin 17	0.670
CAV1	caveolin 1, caveolae protein, 22kDa	0.665
BTRC	beta-transducin repeat containing	0.583
FGFR1	fibroblast growth factor receptor 1	0.574
KRT19	keratin 19	0.570
TCF4	transcription factor 4	0.484
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.473
YAP1	Yes-associated protein 1	0.467	Mouse
NCOR2	nuclear receptor corepressor 2	0.456
KRT14	keratin 14	0.449
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.318
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.271
JUP	junction plakoglobin	0.268
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.255
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.248
SRSF6	serine/arginine-rich splicing factor 6	0.223
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.209
KRT18	keratin 18	0.205
PPL	periplakin	0.203
KRT6A	keratin 6A	0.200	Human
HR	hairless homolog (mouse)	0.189
INADL	InaD-like (Drosophila)	0.187
SRSF4	serine/arginine-rich splicing factor 4	0.167	Human
KRT5	keratin 5	0.166	Human
KRT6B	keratin 6B	0.161	Human
RXRA	retinoid X receptor, alpha	0.160
PKP3	plakophilin 3	0.133
TRIM29	tripartite motif containing 29	0.132
KRT6C	keratin 6C	0.118	Human
FGF10	fibroblast growth factor 10	0.117
HIPK2	homeodomain interacting protein kinase 2	0.113
HNF4A	hepatocyte nuclear factor 4, alpha	0.110
FGF1	fibroblast growth factor 1 (acidic)	0.108	Human
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.099
RARA	retinoic acid receptor, alpha	0.097
ESR1	estrogen receptor 1	0.082
KRT1	keratin 1	0.082	Human
KLK10	kallikrein-related peptidase 10	0.079
DSP	desmoplakin	0.067
PSEN1	presenilin 1	0.066
LIN7A	lin-7 homolog A (C. elegans)	0.065
SDC2	syndecan 2	0.065
FBXW11	F-box and WD repeat domain containing 11	0.063
GSK3B	glycogen synthase kinase 3 beta	0.063
AR	androgen receptor	0.060
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.056
C19orf50	chromosome 19 open reading frame 50	0.053
S100A2	S100 calcium binding protein A2	0.051
GJB3	gap junction protein, beta 3, 31kDa	0.050
ESRRG	estrogen-related receptor gamma	0.050
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.049
INHBA	inhibin, beta A	0.047
FGF7	fibroblast growth factor 7	0.046
SPRR1A	small proline-rich protein 1A	0.045
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.045
KRT34	keratin 34	0.044
KRT75	keratin 75	0.044	Human
FGF8	fibroblast growth factor 8 (androgen-induced)	0.044
GLIS2	GLIS family zinc finger 2	0.042
ALOX12	arachidonate 12-lipoxygenase	0.041
FGFR3	fibroblast growth factor receptor 3	0.040
HAP1	huntingtin-associated protein 1	0.039
SPRR1B	small proline-rich protein 1B	0.039
SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.039
EPS8	epidermal growth factor receptor pathway substrate 8	0.039
FGFBP1	fibroblast growth factor binding protein 1	0.038
SATB2	SATB homeobox 2	0.037
AMOTL2	angiomotin like 2	0.034
SRRM1	serine/arginine repetitive matrix 1	0.032
CABLES1	Cdk5 and Abl enzyme substrate 1	0.032
EGFR	epidermal growth factor receptor	0.031
NCOR1	nuclear receptor corepressor 1	0.030
F11R	F11 receptor	0.029
LYPD3	LY6/PLAUR domain containing 3	0.029
APC	adenomatous polyposis coli	0.029
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.029
GYPC	glycophorin C (Gerbich blood group)	0.028
FGF4	fibroblast growth factor 4	0.027	Human
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.027
HDAC1	histone deacetylase 1	0.026
PGR	progesterone receptor	0.026
KRT33B	keratin 33B	0.025
KDM1A	lysine (K)-specific demethylase 1A	0.025
SFN	stratifin	0.025	Mouse
KRT9	keratin 9	0.024
KRT16	keratin 16	0.024
S1PR5	sphingosine-1-phosphate receptor 5	0.024
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.024
BNC1	basonuclin 1	0.024
DSG3	desmoglein 3	0.023
FGF18	fibroblast growth factor 18	0.023
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.023
GJB5	gap junction protein, beta 5, 31.1kDa	0.023
WNT1	wingless-type MMTV integration site family, member 1	0.022	Human
TGFA	transforming growth factor, alpha	0.022
LY6G6C	lymphocyte antigen 6 complex, locus G6C	0.022
KIAA1377	KIAA1377	0.022
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.021
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.021
COL17A1	collagen, type XVII, alpha 1	0.020
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.020
THBS1	thrombospondin 1	0.020
TJP1	tight junction protein 1 (zona occludens 1)	0.020
TG	thyroglobulin	0.019
BCL2L1	BCL2-like 1	0.019
KRT81	keratin 81	0.019	Human
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.019	Human
PKP2	plakophilin 2	0.018
GPR87	G protein-coupled receptor 87	0.018
LOR	loricrin	0.018
DAXX	death-domain associated protein	0.018
NCK2	NCK adaptor protein 2	0.017
OSMR	oncostatin M receptor	0.017
DSC3	desmocollin 3	0.017	Human
VCAM1	vascular cell adhesion molecule 1	0.017
TP73	tumor protein p73	0.017
EP300	E1A binding protein p300	0.016
FGF2	fibroblast growth factor 2 (basic)	0.016	Human
IVL	involucrin	0.016
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.016
USP42	ubiquitin specific peptidase 42	0.016
SLURP1	secreted LY6/PLAUR domain containing 1	0.016	Mouse
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.016
SKIL	SKI-like oncogene	0.016
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.016
PAX8	paired box 8	0.016
PTHLH	parathyroid hormone-like hormone	0.015
VEGFC	vascular endothelial growth factor C	0.015
COL13A1	collagen, type XIII, alpha 1	0.015
SFRP1	secreted frizzled-related protein 1	0.015
KCNK7	potassium channel, subfamily K, member 7	0.015
LY6D	lymphocyte antigen 6 complex, locus D	0.015
SDC1	syndecan 1	0.014
GRHL2	grainyhead-like 2 (Drosophila)	0.014
FXYD3	FXYD domain containing ion transport regulator 3	0.014
SKP1	S-phase kinase-associated protein 1	0.014
KIAA1217	KIAA1217	0.014
JUB	jub, ajuba homolog (Xenopus laevis)	0.014
S100A14	S100 calcium binding protein A14	0.014
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.014
RNPS1	RNA binding protein S1, serine-rich domain	0.014
CTNNBIP1	catenin, beta interacting protein 1	0.014
PRKCA	protein kinase C, alpha	0.014
TFCP2L1	transcription factor CP2-like 1	0.013
GJA1	gap junction protein, alpha 1, 43kDa	0.013
PLK2	polo-like kinase 2	0.013
TACSTD2	tumor-associated calcium signal transducer 2	0.013
AMOTL1	angiomotin like 1	0.013
OTP	orthopedia homeobox	0.013
EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.013
FGF3	fibroblast growth factor 3	0.013	Human
WNT7A	wingless-type MMTV integration site family, member 7A	0.012	Human
CALD1	caldesmon 1	0.012
KRT2	keratin 2	0.012
TOE1	target of EGR1, member 1 (nuclear)	0.012
KRT85	keratin 85	0.012	Human
LAMC2	laminin, gamma 2	0.012
KRT4	keratin 4	0.012	Human
CAV2	caveolin 2	0.012
PTPRD	protein tyrosine phosphatase, receptor type, D	0.012	Human
KRT31	keratin 31	0.012
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.012
RHOD	ras homolog gene family, member D	0.012
DSG1	desmoglein 1	0.012
EDN2	endothelin 2	0.012
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.012
TGFB2	transforming growth factor, beta 2	0.012
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.011
USP2	ubiquitin specific peptidase 2	0.011
ITGB6	integrin, beta 6	0.011
SP1	Sp1 transcription factor	0.011
NCOA1	nuclear receptor coactivator 1	0.011
DCN	decorin	0.011
UNC119	unc-119 homolog (C. elegans)	0.011
WWTR1	WW domain containing transcription regulator 1	0.011
SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.011
VCL	vinculin	0.011
HNF1A	HNF1 homeobox A	0.011
H3F3B	H3 histone, family 3B (H3.3B)	0.011
SHH	sonic hedgehog	0.011
DDR1	discoidin domain receptor tyrosine kinase 1	0.011
PAX9	paired box 9	0.011
ESRP1	epithelial splicing regulatory protein 1	0.011
FAT2	FAT tumor suppressor homolog 2 (Drosophila)	0.011
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.011
KLK7	kallikrein-related peptidase 7	0.010
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.010
MT2A	metallothionein 2A	0.010
MEST	mesoderm specific transcript homolog (mouse)	0.010
NKD2	naked cuticle homolog 2 (Drosophila)	0.010
MAT2A	methionine adenosyltransferase II, alpha	0.010
KRT13	keratin 13	0.010
S100A4	S100 calcium binding protein A4	0.010
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.010
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.010
FZD10	frizzled homolog 10 (Drosophila)	0.010