IMP

Process View

Homo sapiens

15 genes annotated in human

Multi-species View

regulation of interleukin 12 production

GO:0032655

Any process that modulates the frequency, rate, or extent of interleukin-12 production.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 12 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 12 production" (in gray)

Name	Description	Probability	Func Analog Organism
MYD88	myeloid differentiation primary response gene (88)	0.966
B2M	beta-2-microglobulin	0.965
IRAK2	interleukin-1 receptor-associated kinase 2	0.899	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.839	Human
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.686
HLA-E	major histocompatibility complex, class I, E	0.675	Human
HLA-G	major histocompatibility complex, class I, G	0.543
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.513
HLA-B	major histocompatibility complex, class I, B	0.490
TRAF6	TNF receptor-associated factor 6	0.446	Mouse
HLA-F	major histocompatibility complex, class I, F	0.411	Human
HLA-A	major histocompatibility complex, class I, A	0.385	Human
HLA-C	major histocompatibility complex, class I, C	0.366	Human
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.341
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.341
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.288	Mouse
PILRA	paired immunoglobin-like type 2 receptor alpha	0.280
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.274	Mouse
IRAK3	interleukin-1 receptor-associated kinase 3	0.113
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.100
IL23A	interleukin 23, alpha subunit p19	0.100
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.090
IRF9	interferon regulatory factor 9	0.085
STAT2	signal transducer and activator of transcription 2, 113kDa	0.080
TAPBP	TAP binding protein (tapasin)	0.074
CD40	CD40 molecule, TNF receptor superfamily member 5	0.068	Mouse Rat
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.058
PTAFR	platelet-activating factor receptor	0.054
PELI3	pellino homolog 3 (Drosophila)	0.050
TRAF1	TNF receptor-associated factor 1	0.047
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.046
CDHR2	cadherin-related family member 2	0.040
CTSS	cathepsin S	0.040
HSPE1	heat shock 10kDa protein 1 (chaperonin 10)	0.038
PYCARD	PYD and CARD domain containing	0.037
SIGLEC7	sialic acid binding Ig-like lectin 7	0.035
LY96	lymphocyte antigen 96	0.030
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.029
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.028
IRF7	interferon regulatory factor 7	0.026
BIRC3	baculoviral IAP repeat containing 3	0.025
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.024	Human
SOCS3	suppressor of cytokine signaling 3	0.023
TICAM2	toll-like receptor adaptor molecule 2	0.023
IRAK4	interleukin-1 receptor-associated kinase 4	0.023
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.022
ICAM1	intercellular adhesion molecule 1	0.021
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.020	Human
CD14	CD14 molecule	0.020
HK3	hexokinase 3 (white cell)	0.019
TRAF3	TNF receptor-associated factor 3	0.019
TLR2	toll-like receptor 2	0.019
HFE	hemochromatosis	0.017	Human
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.015
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.015
IL2RG	interleukin 2 receptor, gamma	0.015
CXCL9	chemokine (C-X-C motif) ligand 9	0.014
SLAMF7	SLAM family member 7	0.014
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.013
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.013
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.013	Human
CMKLR1	chemokine-like receptor 1	0.013	Mouse
VNN2	vanin 2	0.013
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.013	Human
IRF1	interferon regulatory factor 1	0.013	Mouse
NLRP3	NLR family, pyrin domain containing 3	0.013
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.012
TLR4	toll-like receptor 4	0.012
TAPBPL	TAP binding protein-like	0.012
IL15RA	interleukin 15 receptor, alpha	0.012
SLAMF1	signaling lymphocytic activation molecule family member 1	0.012
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.011	Mouse
SIGLEC9	sialic acid binding Ig-like lectin 9	0.011
ARRB1	arrestin, beta 1	0.011
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.011
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.011
PLEK	pleckstrin	0.011
C1orf38	chromosome 1 open reading frame 38	0.010
TPP1	tripeptidyl peptidase I	0.010
IL2RA	interleukin 2 receptor, alpha	0.010