IMP

Process View

Homo sapiens

19 genes annotated in human

Multi-species View

muscle organ morphogenesis

GO:0048644

The process in which the anatomical structures of muscle are generated and organized.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "muscle organ morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "muscle organ morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
TRIM63	tripartite motif containing 63	0.999
TNNC1	troponin C type 1 (slow)	0.996
TNNI1	troponin I type 1 (skeletal, slow)	0.991	Human Mouse
SMYD1	SET and MYND domain containing 1	0.925
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.825
TPM1	tropomyosin 1 (alpha)	0.812
ACTA1	actin, alpha 1, skeletal muscle	0.783
MYH9	myosin, heavy chain 9, non-muscle	0.773
MYOD1	myogenic differentiation 1	0.753
TPM2	tropomyosin 2 (beta)	0.625	Human
IK	IK cytokine, down-regulator of HLA II	0.581	Worm
TNNT3	troponin T type 3 (skeletal, fast)	0.575	Human
TNNT2	troponin T type 2 (cardiac)	0.548
SNW1	SNW domain containing 1	0.545
ESR2	estrogen receptor 2 (ER beta)	0.535
ESR1	estrogen receptor 1	0.525
GSK3B	glycogen synthase kinase 3 beta	0.509
TBX5	T-box 5	0.504
ACTN2	actinin, alpha 2	0.502
CKM	creatine kinase, muscle	0.492
SMAD3	SMAD family member 3	0.469
COX6A2	cytochrome c oxidase subunit VIa polypeptide 2	0.415
ACVR1B	activin A receptor, type IB	0.390
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.384
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.367
PDLIM7	PDZ and LIM domain 7 (enigma)	0.342
BMPR1A	bone morphogenetic protein receptor, type IA	0.325
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.324
TNNI2	troponin I type 2 (skeletal, fast)	0.310	Human
INADL	InaD-like (Drosophila)	0.291
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.283
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.258
MYH1	myosin, heavy chain 1, skeletal muscle, adult	0.244	Human
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.231	Human
TCAP	titin-cap (telethonin)	0.229
SETD8	SET domain containing (lysine methyltransferase) 8	0.226
MYOZ1	myozenin 1	0.223
FLNA	filamin A, alpha	0.196
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.188	Human
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.182
SKIL	SKI-like oncogene	0.170
MFAP1	microfibrillar-associated protein 1	0.161
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.159	Human
MYBPC2	myosin binding protein C, fast type	0.158
YAP1	Yes-associated protein 1	0.155
HNF4A	hepatocyte nuclear factor 4, alpha	0.152
FGF1	fibroblast growth factor 1 (acidic)	0.148
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.142
LDB3	LIM domain binding 3	0.136
CTGF	connective tissue growth factor	0.131
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.129
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.124
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.121
SMAD9	SMAD family member 9	0.117
ACTN1	actinin, alpha 1	0.116
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.114
JAG1	jagged 1	0.114
GATA4	GATA binding protein 4	0.113	Zebrafish
MYBPC1	myosin binding protein C, slow type	0.111
TTN	titin	0.107
ACTN3	actinin, alpha 3	0.103
CHD3	chromodomain helicase DNA binding protein 3	0.100
CXXC5	CXXC finger protein 5	0.098
ZNF830	zinc finger protein 830	0.086
ZYX	zyxin	0.085
MYOG	myogenin (myogenic factor 4)	0.083
MYOZ2	myozenin 2	0.082
HAP1	huntingtin-associated protein 1	0.081
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.080
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.078
SNIP1	Smad nuclear interacting protein 1	0.077
TNNC2	troponin C type 2 (fast)	0.075	Human
WNT3A	wingless-type MMTV integration site family, member 3A	0.070
KRT14	keratin 14	0.068
NEB	nebulin	0.064
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.061
COL4A2	collagen, type IV, alpha 2	0.058
CNN1	calponin 1, basic, smooth muscle	0.058
MYBPH	myosin binding protein H	0.057
TNNI3	troponin I type 3 (cardiac)	0.054
SFN	stratifin	0.051
TAL1	T-cell acute lymphocytic leukemia 1	0.051	Human
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.051
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.050	Human
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.049	Human
PAX8	paired box 8	0.048
TPM4	tropomyosin 4	0.046	Human
COL4A1	collagen, type IV, alpha 1	0.046
FGF7	fibroblast growth factor 7	0.044
JUP	junction plakoglobin	0.041
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.039
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.039
MYH2	myosin, heavy chain 2, skeletal muscle, adult	0.038	Human
TNNT1	troponin T type 1 (skeletal, slow)	0.038	Human
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.037
GATA2	GATA binding protein 2	0.037
SMPX	small muscle protein, X-linked	0.037
FOXA2	forkhead box A2	0.037
CALD1	caldesmon 1	0.036
EP300	E1A binding protein p300	0.035
EPAS1	endothelial PAS domain protein 1	0.034
ACTC1	actin, alpha, cardiac muscle 1	0.034
NOTCH3	notch 3	0.033
SP1	Sp1 transcription factor	0.033
FRMD5	FERM domain containing 5	0.033
PTRF	polymerase I and transcript release factor	0.032
HAND2	heart and neural crest derivatives expressed 2	0.031	Human
TAGLN2	transgelin 2	0.030
CORO1C	coronin, actin binding protein, 1C	0.030
MYBPC3	myosin binding protein C, cardiac	0.030
FGFR1	fibroblast growth factor receptor 1	0.030
TCF4	transcription factor 4	0.029
TAGLN	transgelin	0.028
AMOTL2	angiomotin like 2	0.028
CAV3	caveolin 3	0.027
PDX1	pancreatic and duodenal homeobox 1	0.027
CASQ2	calsequestrin 2 (cardiac muscle)	0.027
APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.026
SLN	sarcolipin	0.026
MYL7	myosin, light chain 7, regulatory	0.026	Human
KRT8	keratin 8	0.025
MB	myoglobin	0.024
MED25	mediator complex subunit 25	0.024
MAML1	mastermind-like 1 (Drosophila)	0.024
CNN2	calponin 2	0.024
DES	desmin	0.023
CTBP2	C-terminal binding protein 2	0.023
COL1A1	collagen, type I, alpha 1	0.022
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.022
WNT5A	wingless-type MMTV integration site family, member 5A	0.022	Mouse
RARA	retinoic acid receptor, alpha	0.022
PGAM2	phosphoglycerate mutase 2 (muscle)	0.022
SRPK3	SRSF protein kinase 3	0.021
TGFBR1	transforming growth factor, beta receptor 1	0.020
CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)	0.020
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.020
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.019
CTNNBL1	catenin, beta like 1	0.019
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.019
RPL3L	ribosomal protein L3-like	0.019
ARF4	ADP-ribosylation factor 4	0.018
DSG2	desmoglein 2	0.018
MARK3	MAP/microtubule affinity-regulating kinase 3	0.018
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.018
MYF6	myogenic factor 6 (herculin)	0.018	Mouse
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.018
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.018
NCOR2	nuclear receptor corepressor 2	0.017
CDX2	caudal type homeobox 2	0.017
PSEN1	presenilin 1	0.017
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.017
AKAP6	A kinase (PRKA) anchor protein 6	0.017
TBX1	T-box 1	0.017
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.017	Human
MYF5	myogenic factor 5	0.016	Mouse
SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	0.016
ATXN1L	ataxin 1-like	0.015
KRT5	keratin 5	0.015
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.015
LAD1	ladinin 1	0.015
MYH4	myosin, heavy chain 4, skeletal muscle	0.015	Human
MYL9	myosin, light chain 9, regulatory	0.015	Human
FZD1	frizzled homolog 1 (Drosophila)	0.014	Mouse
FBP2	fructose-1,6-bisphosphatase 2	0.014
MYOM1	myomesin 1, 185kDa	0.014
SOX11	SRY (sex determining region Y)-box 11	0.014
LMO1	LIM domain only 1 (rhombotin 1)	0.014
AXIN1	axin 1	0.014
TNNI3K	TNNI3 interacting kinase	0.014
PLEC	plectin	0.014
CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.014
C19orf50	chromosome 19 open reading frame 50	0.014
SIX6	SIX homeobox 6	0.014
HOXD12	homeobox D12	0.013
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.013
ITGB4	integrin, beta 4	0.013
LMOD2	leiomodin 2 (cardiac)	0.013
WDR1	WD repeat domain 1	0.013
HSPB3	heat shock 27kDa protein 3	0.013
DSP	desmoplakin	0.013	Mouse
CUEDC2	CUE domain containing 2	0.013
JUB	jub, ajuba homolog (Xenopus laevis)	0.013
MYL12B	myosin, light chain 12B, regulatory	0.013	Human
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.013
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.012
ZFPM1	zinc finger protein, multitype 1	0.012	Human Mouse
DUSP13	dual specificity phosphatase 13	0.012
RAPSN	receptor-associated protein of the synapse	0.012
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.012
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.012
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.012
PHOX2A	paired-like homeobox 2a	0.011
CD151	CD151 molecule (Raph blood group)	0.011
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.011
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.011
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.011
ITGB1BP3	integrin beta 1 binding protein 3	0.011
CSRP1	cysteine and glycine-rich protein 1	0.011
POU4F2	POU class 4 homeobox 2	0.011
LHX5	LIM homeobox 5	0.011
NPPB	natriuretic peptide B	0.011
SYNPO2L	synaptopodin 2-like	0.011
HR	hairless homolog (mouse)	0.011
NRAP	nebulin-related anchoring protein	0.011
IFITM3	interferon induced transmembrane protein 3 (1-8U)	0.011
COL5A2	collagen, type V, alpha 2	0.011
CREBBP	CREB binding protein	0.010
DSG1	desmoglein 1	0.010
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.010