IMP

Process View

Homo sapiens

16 genes annotated in human

negative regulation of blood vessel endothelial cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of blood vessel endothelial cell migration"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of blood vessel endothelial cell migration" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.979
JAG1	jagged 1	0.933	Human
TEK	TEK tyrosine kinase, endothelial	0.921
NOTCH1	notch 1	0.835
BMP2	bone morphogenetic protein 2	0.731
TGFB1	transforming growth factor, beta 1	0.725
FKBP1A	FK506 binding protein 1A, 12kDa	0.708
ENG	endoglin	0.677
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.676	Human
FGF1	fibroblast growth factor 1 (acidic)	0.455	Human
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.421	Human
NOTCH3	notch 3	0.400	Human
FGA	fibrinogen alpha chain	0.344
A2M	alpha-2-macroglobulin	0.274
KLF4	Kruppel-like factor 4 (gut)	0.215
FGFR1	fibroblast growth factor receptor 1	0.214
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.154
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.148
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.143
MEF2C	myocyte enhancer factor 2C	0.139
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.105
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.101
GFI1B	growth factor independent 1B transcription repressor	0.089
FGF10	fibroblast growth factor 10	0.088	Human
MEF2A	myocyte enhancer factor 2A	0.076
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.062
TGFB3	transforming growth factor, beta 3	0.061
NRP1	neuropilin 1	0.047
SMAD7	SMAD family member 7	0.047
HP	haptoglobin	0.046
DLL1	delta-like 1 (Drosophila)	0.046	Human
GDF5	growth differentiation factor 5	0.046
THBS1	thrombospondin 1	0.045
NOTCH2	notch 2	0.045	Human
ANGPT2	angiopoietin 2	0.040
PRKD2	protein kinase D2	0.039
PRKG1	protein kinase, cGMP-dependent, type I	0.038
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.037
ACVR1	activin A receptor, type I	0.036	Human
CTGF	connective tissue growth factor	0.034
KLF6	Kruppel-like factor 6	0.034	Human
DCN	decorin	0.033
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.033
APOC1	apolipoprotein C-I	0.032
FOXP3	forkhead box P3	0.030
TGFBR1	transforming growth factor, beta receptor 1	0.029	Human
FGF7	fibroblast growth factor 7	0.028	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.028
SMAD1	SMAD family member 1	0.028
ANGPT1	angiopoietin 1	0.025	Human
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.025
XIAP	X-linked inhibitor of apoptosis	0.024
HDAC3	histone deacetylase 3	0.022
DUSP1	dual specificity phosphatase 1	0.022
FGF2	fibroblast growth factor 2 (basic)	0.022
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.022
FN1	fibronectin 1	0.021
SKIL	SKI-like oncogene	0.020
GABARAP	GABA(A) receptor-associated protein	0.020
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.019
RXRA	retinoid X receptor, alpha	0.018
FSTL1	follistatin-like 1	0.018
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.018
MAPK7	mitogen-activated protein kinase 7	0.017
NCOR1	nuclear receptor corepressor 1	0.017
JUN	jun proto-oncogene	0.017
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.016
BMP4	bone morphogenetic protein 4	0.016
TIMP3	TIMP metallopeptidase inhibitor 3	0.015
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.014
LCAT	lecithin-cholesterol acyltransferase	0.014
HDAC4	histone deacetylase 4	0.014	Human
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.014
ASRGL1	asparaginase like 1	0.014
CTBP1	C-terminal binding protein 1	0.013
YAP1	Yes-associated protein 1	0.013
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.013
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.013
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.013
ALB	albumin	0.013
FBLN1	fibulin 1	0.013
ACVR2B	activin A receptor, type IIB	0.013
FAF1	Fas (TNFRSF6) associated factor 1	0.012
HSPG2	heparan sulfate proteoglycan 2	0.012
WWTR1	WW domain containing transcription regulator 1	0.012
LRP1	low density lipoprotein receptor-related protein 1	0.012
ANTXR2	anthrax toxin receptor 2	0.011
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.011
COL4A1	collagen, type IV, alpha 1	0.011
EMP1	epithelial membrane protein 1	0.011
APOA1	apolipoprotein A-I	0.011	Human
VEGFC	vascular endothelial growth factor C	0.010
JAG2	jagged 2	0.010	Human
NRP2	neuropilin 2	0.010
BCL6	B-cell CLL/lymphoma 6	0.010
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.010