IMP

Process View

Mus musculus

8 genes annotated in mouse

response to cadmium ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to cadmium ion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to cadmium ion" (in gray)

Name	Description	Probability	Func Analog Organism
Mt1	metallothionein 1	0.903	Zebrafish
Mt2	metallothionein 2	0.885	Zebrafish
Atf2	activating transcription factor 2	0.691
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.577	Mouse
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.541	Mouse
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.490
Cps1	carbamoyl-phosphate synthetase 1	0.430
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.414	Mouse
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.406	Rat
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.340
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.326	Mouse
Otc	ornithine transcarbamylase	0.310
Hrg	histidine-rich glycoprotein	0.304
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.282
Ccna2	cyclin A2	0.281
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.268	Mouse
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.259	Mouse
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.258
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.238
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.233
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.230	Mouse
F9	coagulation factor IX	0.228
Akr1c6	aldo-keto reductase family 1, member C6	0.185
Aadac	arylacetamide deacetylase (esterase)	0.183
Mapk14	mitogen-activated protein kinase 14	0.181	Mouse Fly
Pten	phosphatase and tensin homolog	0.171
Mapk1	mitogen-activated protein kinase 1	0.160	Fly
Mup5	major urinary protein 5	0.157
Sult1d1	sulfotransferase family 1D, member 1	0.154
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.136
Prkce	protein kinase C, epsilon	0.125
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.111
Apoh	apolipoprotein H	0.108
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.106
Tapbp	TAP binding protein	0.105
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.102
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.099	Mouse
Rdh7	retinol dehydrogenase 7	0.098
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.098
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.081	Rat
Mapk8	mitogen-activated protein kinase 8	0.081
Mbl2	mannose-binding lectin (protein C) 2	0.077
Sult1b1	sulfotransferase family 1B, member 1	0.073
G6pc	glucose-6-phosphatase, catalytic	0.070
Apoc4	apolipoprotein C-IV	0.069
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.066	Rat
Upp2	uridine phosphorylase 2	0.064
Mtap2	microtubule-associated protein 2	0.063
Pon1	paraoxonase 1	0.063
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.063	Mouse
Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	0.060	Worm
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.060
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.059	Mouse
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.058
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.056
Sult2a2	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2	0.056
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.054
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.054
Keg1	kidney expressed gene 1	0.054
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.053
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.052
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.050
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.050
Abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.046	Worm
Ces1c	carboxylesterase 1C	0.045
Tdo2	tryptophan 2,3-dioxygenase	0.045
Abcb1b	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	0.044	Worm
Mug1	murinoglobulin 1	0.043
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.042
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.041
Inmt	indolethylamine N-methyltransferase	0.041
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.041	Mouse
Bmp4	bone morphogenetic protein 4	0.041
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.040
Mup3	major urinary protein 3	0.040
Rac1	RAS-related C3 botulinum substrate 1	0.040
Ednra	endothelin receptor type A	0.039
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.038
Crp	C-reactive protein, pentraxin-related	0.038
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.037	Mouse
Klc1	kinesin light chain 1	0.037
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.036
Pea15a	phosphoprotein enriched in astrocytes 15A	0.035
Car1	carbonic anhydrase 1	0.033
Afm	afamin	0.032
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.032
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.031
Tgfbr2	transforming growth factor, beta receptor II	0.031
Akr1d1	aldo-keto reductase family 1, member D1	0.031
Ces1g	carboxylesterase 1G	0.030
Hgd	homogentisate 1, 2-dioxygenase	0.030
F13b	coagulation factor XIII, beta subunit	0.030
Trp53	transformation related protein 53	0.029
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.029	Mouse
Tmprss15	transmembrane protease, serine 15	0.029
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.028
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.028
Mapk9	mitogen-activated protein kinase 9	0.028
C9	complement component 9	0.028
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.026	Worm
Ces3a	carboxylesterase 3A	0.025
Ccne1	cyclin E1	0.025
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.025	Rat
Vsig4	V-set and immunoglobulin domain containing 4	0.024
Fos	FBJ osteosarcoma oncogene	0.024
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.024
Gsta4	glutathione S-transferase, alpha 4	0.024
Cfhr1	complement factor H-related 1	0.023
Lect2	leukocyte cell-derived chemotaxin 2	0.023
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.023
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.023
Tnfsf15	tumor necrosis factor (ligand) superfamily, member 15	0.022
Uox	urate oxidase	0.022
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.022
Mup4	major urinary protein 4	0.022
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.022
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.022
Azgp1	alpha-2-glycoprotein 1, zinc	0.022
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.021
Axin1	axin 1	0.021
Lipc	lipase, hepatic	0.021
Csn1s1	casein alpha s1	0.021
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.021
Atf3	activating transcription factor 3	0.020
Csn1s2b	casein alpha s2-like B	0.020
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.020
Ccnd1	cyclin D1	0.020
Nsfl1c	NSFL1 (p97) cofactor (p47)	0.020
Dlg4	discs, large homolog 4 (Drosophila)	0.020
Adh1	alcohol dehydrogenase 1 (class I)	0.020
Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	0.019	Rat
Mapkapk2	MAP kinase-activated protein kinase 2	0.019
Gstm3	glutathione S-transferase, mu 3	0.019
Cml2	camello-like 2	0.019
Ufd1l	ubiquitin fusion degradation 1 like	0.019
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.019
Aqp8	aquaporin 8	0.019
Cyp2c55	cytochrome P450, family 2, subfamily c, polypeptide 55	0.018
Vmn1r51	vomeronasal 1 receptor 51	0.018
Ep300	E1A binding protein p300	0.018
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.018
Bcl6	B-cell leukemia/lymphoma 6	0.018
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.018
Mbl1	mannose-binding lectin (protein A) 1	0.018
Cyp3a41b	cytochrome P450, family 3, subfamily a, polypeptide 41B	0.017	Rat
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.017
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.017
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.017
Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	0.016
Arc	activity regulated cytoskeletal-associated protein	0.016
Ces2a	carboxylesterase 2A	0.016
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.016	Mouse
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.016
Fbp1	fructose bisphosphatase 1	0.016
Hao2	hydroxyacid oxidase 2	0.016
Omt2b	oocyte maturation, beta	0.016
Hamp	hepcidin antimicrobial peptide	0.016
Gsk3b	glycogen synthase kinase 3 beta	0.016
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.015
Dsg1a	desmoglein 1 alpha	0.015
Gm14743	predicted gene 14743	0.015
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.015
Smad4	MAD homolog 4 (Drosophila)	0.015
Acvr1	activin A receptor, type 1	0.014
Klc2	kinesin light chain 2	0.014
Cdk4	cyclin-dependent kinase 4	0.014
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.014
Rrm2	ribonucleotide reductase M2	0.014
Rara	retinoic acid receptor, alpha	0.013
Ces1f	carboxylesterase 1F	0.013
Actn2	actinin alpha 2	0.013
Alb	albumin	0.013
Glyat	glycine-N-acyltransferase	0.013
Vnn3	vanin 3	0.013
Cstb	cystatin B	0.012
Notch2	Notch gene homolog 2 (Drosophila)	0.012
Mat1a	methionine adenosyltransferase I, alpha	0.012
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.012
Inhbc	inhibin beta-C	0.012
Fpr3	formyl peptide receptor 3	0.012
Fpr-rs4	formyl peptide receptor, related sequence 4	0.012
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.012
4930579C15Rik	RIKEN cDNA 4930579C15 gene	0.012
Mkl2	MKL/myocardin-like 2	0.012
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.012
Sqstm1	sequestosome 1	0.012
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.011
Gsta3	glutathione S-transferase, alpha 3	0.011
Klkb1	kallikrein B, plasma 1	0.011
Smr3a	submaxillary gland androgen regulated protein 3A	0.011
Tmem205	transmembrane protein 205	0.011
Aldob	aldolase B, fructose-bisphosphate	0.011
Vmn1r45	vomeronasal 1 receptor 45	0.011
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.011
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.011
Gm10228	predicted gene 10228	0.011
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.011
Foxi3	forkhead box I3	0.011
1700074P13Rik	RIKEN cDNA 1700074P13 gene	0.011
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.010
Ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.010
Hist1h1a	histone cluster 1, H1a	0.010
Agxt	alanine-glyoxylate aminotransferase	0.010
Spag9	sperm associated antigen 9	0.010