IMP
Process View
antigen processing and presentation of peptide antigen via mhc class ii
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
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Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation of peptide antigen via mhc class ii"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| H2-Aa | histocompatibility 2, class II antigen A, alpha | 1.000 | ||
| Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | 0.999 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.996 | ||
| H2-DMa | histocompatibility 2, class II, locus DMa | 0.988 | ||
| H2-Eb1 | histocompatibility 2, class II antigen E beta | 0.984 | ||
| H2-DMb2 | histocompatibility 2, class II, locus Mb2 | 0.818 | ||
| Lyz2 | lysozyme 2 | 0.794 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.463 | ||
| C1qc | complement component 1, q subcomponent, C chain | 0.451 | ||
| Mavs | mitochondrial antiviral signaling protein | 0.448 | ||
| Cd40 | CD40 antigen | 0.378 | ||
| Lat | linker for activation of T cells | 0.344 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.344 | ||
| Ciita | class II transactivator | 0.212 | ||
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.145 | ||
| Cd2 | CD2 antigen | 0.134 | ||
| H2-Ob | histocompatibility 2, O region beta locus | 0.130 | Mouse | |
| Tgfb1 | transforming growth factor, beta 1 | 0.080 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.072 | ||
| Lyz1 | lysozyme 1 | 0.069 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.067 | ||
| Lamp1 | lysosomal-associated membrane protein 1 | 0.065 | ||
| Ly86 | lymphocyte antigen 86 | 0.049 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.048 | ||
| Irf5 | interferon regulatory factor 5 | 0.047 | ||
| Clec4n | C-type lectin domain family 4, member n | 0.043 | ||
| Aif1 | allograft inflammatory factor 1 | 0.042 | ||
| AF251705 | cDNA sequence AF251705 | 0.038 | ||
| Tcra | T-cell receptor alpha chain | 0.037 | ||
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.035 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.034 | ||
| Cd79b | CD79B antigen | 0.032 | ||
| Ctsb | cathepsin B | 0.032 | ||
| H2-Oa | histocompatibility 2, O region alpha locus | 0.030 | ||
| Aim2 | absent in melanoma 2 | 0.028 | ||
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.028 | ||
| Lck | lymphocyte protein tyrosine kinase | 0.028 | ||
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.027 | ||
| Cd22 | CD22 antigen | 0.027 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.025 | ||
| Blk | B lymphoid kinase | 0.025 | ||
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.024 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.024 | ||
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.022 | ||
| Ms4a1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.021 | ||
| Rhoh | ras homolog gene family, member H | 0.019 | ||
| Csf1r | colony stimulating factor 1 receptor | 0.019 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.019 | ||
| Cr2 | complement receptor 2 | 0.018 | ||
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.018 | ||
| Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.017 | ||
| Ly6d | lymphocyte antigen 6 complex, locus D | 0.017 | ||
| Napsa | napsin A aspartic peptidase | 0.016 | Mouse | |
| Il7r | interleukin 7 receptor | 0.016 | ||
| Cd3g | CD3 antigen, gamma polypeptide | 0.016 | ||
| Bank1 | B-cell scaffold protein with ankyrin repeats 1 | 0.016 | ||
| Plbd1 | phospholipase B domain containing 1 | 0.015 | ||
| Cd37 | CD37 antigen | 0.015 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.015 | ||
| Fcer2a | Fc receptor, IgE, low affinity II, alpha polypeptide | 0.015 | ||
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.014 | ||
| Rnase6 | ribonuclease, RNase A family, 6 | 0.014 | ||
| Fcrla | Fc receptor-like A | 0.014 | Mouse | |
| Cyba | cytochrome b-245, alpha polypeptide | 0.014 | ||
| Il15 | interleukin 15 | 0.014 | ||
| Cd86 | CD86 antigen | 0.013 | ||
| H2-DMb1 | histocompatibility 2, class II, locus Mb1 | 0.013 | ||
| Tnfrsf13c | tumor necrosis factor receptor superfamily, member 13c | 0.012 | ||
| Traf3ip2 | TRAF3 interacting protein 2 | 0.012 | ||
| Hck | hemopoietic cell kinase | 0.012 | ||
| Itgae | integrin alpha E, epithelial-associated | 0.012 | ||
| Irf8 | interferon regulatory factor 8 | 0.012 | ||
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.011 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.011 | ||
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.011 | ||
| Tifa | TRAF-interacting protein with forkhead-associated domain | 0.011 | ||
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.011 | ||
| Cd19 | CD19 antigen | 0.011 | ||
| Vpreb3 | pre-B lymphocyte gene 3 | 0.010 | ||
| Tnip1 | TNFAIP3 interacting protein 1 | 0.010 | ||
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.010 | ||
| Pld4 | phospholipase D family, member 4 | 0.010 |