IMP
Process View
antigen processing and presentation of peptide antigen via mhc class i
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
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Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation of peptide antigen via mhc class i"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| B2m | beta-2 microglobulin | 1.000 | ||
| Tap1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 1.000 | Human Mouse | |
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.998 | ||
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.997 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.950 | ||
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.950 | ||
| Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.839 | ||
| Tapbp | TAP binding protein | 0.814 | ||
| H2-Q7 | histocompatibility 2, Q region locus 7 | 0.733 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.685 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.611 | ||
| H2-Q6 | histocompatibility 2, Q region locus 6 | 0.354 | ||
| Psmb10 | proteasome (prosome, macropain) subunit, beta type 10 | 0.326 | ||
| Lck | lymphocyte protein tyrosine kinase | 0.310 | ||
| Lat | linker for activation of T cells | 0.243 | ||
| Psme1 | proteasome (prosome, macropain) 28 subunit, alpha | 0.117 | ||
| Il15 | interleukin 15 | 0.104 | ||
| H2-Q8 | histocompatibility 2, Q region locus 8 | 0.097 | ||
| Cd68 | CD68 antigen | 0.094 | ||
| Msr1 | macrophage scavenger receptor 1 | 0.087 | ||
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.082 | ||
| Il7r | interleukin 7 receptor | 0.079 | ||
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.078 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.077 | ||
| H2-D1 | histocompatibility 2, D region locus 1 | 0.076 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.074 | ||
| Clec4n | C-type lectin domain family 4, member n | 0.064 | ||
| Slc40a1 | solute carrier family 40 (iron-regulated transporter), member 1 | 0.057 | ||
| C3 | complement component 3 | 0.055 | ||
| Bst2 | bone marrow stromal cell antigen 2 | 0.054 | ||
| Aif1 | allograft inflammatory factor 1 | 0.051 | ||
| Psme2 | proteasome (prosome, macropain) 28 subunit, beta | 0.050 | ||
| C1qc | complement component 1, q subcomponent, C chain | 0.048 | ||
| H2-K1 | histocompatibility 2, K1, K region | 0.043 | ||
| Apoe | apolipoprotein E | 0.041 | ||
| Tnip1 | TNFAIP3 interacting protein 1 | 0.038 | ||
| Il15ra | interleukin 15 receptor, alpha chain | 0.038 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.036 | ||
| Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | 0.034 | ||
| Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.031 | ||
| AW112010 | expressed sequence AW112010 | 0.031 | ||
| Tcra | T-cell receptor alpha chain | 0.030 | ||
| Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.029 | ||
| Parp10 | poly (ADP-ribose) polymerase family, member 10 | 0.028 | ||
| Cp | ceruloplasmin | 0.026 | ||
| Hcst | hematopoietic cell signal transducer | 0.025 | ||
| Fcna | ficolin A | 0.024 | ||
| Ly6e | lymphocyte antigen 6 complex, locus E | 0.023 | ||
| Cd40 | CD40 antigen | 0.023 | ||
| Lgals9 | lectin, galactose binding, soluble 9 | 0.022 | ||
| H2-Aa | histocompatibility 2, class II antigen A, alpha | 0.022 | ||
| Gm2a | GM2 ganglioside activator protein | 0.022 | ||
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.022 | ||
| Ccr9 | chemokine (C-C motif) receptor 9 | 0.022 | ||
| Cd247 | CD247 antigen | 0.020 | Mouse | |
| Folr2 | folate receptor 2 (fetal) | 0.019 | ||
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.018 | ||
| Calcrl | calcitonin receptor-like | 0.018 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.018 | ||
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.017 | ||
| H2-Q5 | histocompatibility 2, Q region locus 5 | 0.017 | ||
| Ccl9 | chemokine (C-C motif) ligand 9 | 0.016 | ||
| Il2rb | interleukin 2 receptor, beta chain | 0.016 | ||
| Cyba | cytochrome b-245, alpha polypeptide | 0.016 | ||
| Irf1 | interferon regulatory factor 1 | 0.016 | ||
| H2-Eb1 | histocompatibility 2, class II antigen E beta | 0.015 | ||
| Hamp | hepcidin antimicrobial peptide | 0.014 | ||
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.014 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.014 | ||
| Cyp3a11 | cytochrome P450, family 3, subfamily a, polypeptide 11 | 0.014 | ||
| Cd3g | CD3 antigen, gamma polypeptide | 0.014 | ||
| P4hb | prolyl 4-hydroxylase, beta polypeptide | 0.013 | ||
| Ncstn | nicastrin | 0.012 | ||
| Fcgr3 | Fc receptor, IgG, low affinity III | 0.012 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.012 | ||
| Rhoh | ras homolog gene family, member H | 0.012 | ||
| Cd3d | CD3 antigen, delta polypeptide | 0.012 | ||
| Slc15a3 | solute carrier family 15, member 3 | 0.011 | ||
| Cd52 | CD52 antigen | 0.011 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.011 | ||
| Tapbpl | TAP binding protein-like | 0.011 | Human Mouse | |
| Lyz2 | lysozyme 2 | 0.010 |