IMP

Process View

Mus musculus

4 genes annotated in mouse

positive regulation of intracellular steroid hormone receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of intracellular steroid hormone receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of intracellular steroid hormone receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Esr1	estrogen receptor 1 (alpha)	0.997
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.983	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.964
Ar	androgen receptor	0.937
Lepr	leptin receptor	0.827
Kiss1r	KISS1 receptor	0.826
Ghr	growth hormone receptor	0.806
Pten	phosphatase and tensin homolog	0.767
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.753
Amhr2	anti-Mullerian hormone type 2 receptor	0.622
Fshr	follicle stimulating hormone receptor	0.611
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.571
Drd2	dopamine receptor D2	0.526
Gnrh1	gonadotropin releasing hormone 1	0.389
Gnrhr	gonadotropin releasing hormone receptor	0.381
Prlr	prolactin receptor	0.346
Pax8	paired box gene 8	0.346
Bglap	bone gamma carboxyglutamate protein	0.293
Cga	glycoprotein hormones, alpha subunit	0.286
Esr2	estrogen receptor 2 (beta)	0.264
Lep	leptin	0.179
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.157
Pgr	progesterone receptor	0.157
Duox2	dual oxidase 2	0.136
Nhlh2	nescient helix loop helix 2	0.127
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.112
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.098
Ahr	aryl-hydrocarbon receptor	0.092
Vgf	VGF nerve growth factor inducible	0.087
Inha	inhibin alpha	0.087
Bglap2	bone gamma-carboxyglutamate protein 2	0.076
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.076
Lhx3	LIM homeobox protein 3	0.074
Thrb	thyroid hormone receptor beta	0.072
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.066
Kl	klotho	0.065
Rac1	RAS-related C3 botulinum substrate 1	0.064
Egr1	early growth response 1	0.062
Bdnf	brain derived neurotrophic factor	0.054
Igf1	insulin-like growth factor 1	0.045
Apc	adenomatosis polyposis coli	0.043
Braf	Braf transforming gene	0.038
Kit	kit oncogene	0.038
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.036
Fbxo11	F-box protein 11	0.034
Fgf10	fibroblast growth factor 10	0.032
Vdr	vitamin D receptor	0.031
Lhx9	LIM homeobox protein 9	0.030
Irs2	insulin receptor substrate 2	0.030
Lhb	luteinizing hormone beta	0.029
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.029
Npc1	Niemann Pick type C1	0.028
Ctnnb1	catenin (cadherin associated protein), beta 1	0.027
Wwox	WW domain-containing oxidoreductase	0.027
Ncoa6	nuclear receptor coactivator 6	0.027
Foxa2	forkhead box A2	0.026
Inhba	inhibin beta-A	0.026
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.026
Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	0.025
Nos1	nitric oxide synthase 1, neuronal	0.025
Emx2	empty spiracles homolog 2 (Drosophila)	0.024
Hoxa10	homeobox A10	0.023
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.023
Pax2	paired box gene 2	0.022
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.022	Mouse
Adam17	a disintegrin and metallopeptidase domain 17	0.021
Ncoa1	nuclear receptor coactivator 1	0.021
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.021
Emx1	empty spiracles homolog 1 (Drosophila)	0.021
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.020
Ret	ret proto-oncogene	0.019
Prl	prolactin	0.019
Smad3	MAD homolog 3 (Drosophila)	0.018
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.018
Thra	thyroid hormone receptor alpha	0.017
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.017
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.017
Zfp326	zinc finger protein 326	0.017
Clock	circadian locomotor output cycles kaput	0.017
Btg1	B-cell translocation gene 1, anti-proliferative	0.017
Cldn8	claudin 8	0.016
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.016
Egr2	early growth response 2	0.016
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.016
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.015	Rat
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.015
Cnr1	cannabinoid receptor 1 (brain)	0.015
Wsb1	WD repeat and SOCS box-containing 1	0.015
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.014	Rat
Tgfbr1	transforming growth factor, beta receptor I	0.014
Star	steroidogenic acute regulatory protein	0.014
Mrpl28	mitochondrial ribosomal protein L28	0.014
Foxo3	forkhead box O3	0.014
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.014
Plekha5	pleckstrin homology domain containing, family A member 5	0.014
Mc2r	melanocortin 2 receptor	0.014
Myf5	myogenic factor 5	0.013
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.013
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.013
Foxf2	forkhead box F2	0.012
Nf1	neurofibromatosis 1	0.012
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.012
Fkbp4	FK506 binding protein 4	0.012
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.012
Klf5	Kruppel-like factor 5	0.012
Fam13b	family with sequence similarity 13, member B	0.012
Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	0.012
Prokr2	prokineticin receptor 2	0.012
Epas1	endothelial PAS domain protein 1	0.011
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.011
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.011
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.011
Ntf3	neurotrophin 3	0.011
Mark2	MAP/microtubule affinity-regulating kinase 2	0.011
Crhr1	corticotropin releasing hormone receptor 1	0.011
Agtr2	angiotensin II receptor, type 2	0.011
Dohh	deoxyhypusine hydroxylase/monooxygenase	0.011
Tyro3	TYRO3 protein tyrosine kinase 3	0.011
Carm1	coactivator-associated arginine methyltransferase 1	0.011
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.011
Tcfcp2l1	transcription factor CP2-like 1	0.011
Ppp1r8	protein phosphatase 1, regulatory (inhibitor) subunit 8	0.011
Hipk3	homeodomain interacting protein kinase 3	0.011
E2f1	E2F transcription factor 1	0.011
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.011
Mllt6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.011
Otx1	orthodenticle homolog 1 (Drosophila)	0.011
Ythdc1	YTH domain containing 1	0.011
Npy1r	neuropeptide Y receptor Y1	0.011
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.011
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.011
Fubp3	far upstream element (FUSE) binding protein 3	0.011
Stat3	signal transducer and activator of transcription 3	0.011
Ogt	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.010
Rictor	RPTOR independent companion of MTOR, complex 2	0.010
Rpl8	ribosomal protein L8	0.010
Gata3	GATA binding protein 3	0.010
Ctbp2	C-terminal binding protein 2	0.010
Fgfr2	fibroblast growth factor receptor 2	0.010
Stub1	STIP1 homology and U-Box containing protein 1	0.010
Vav3	vav 3 oncogene	0.010
Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	0.010
Bcl2	B-cell leukemia/lymphoma 2	0.010
Tars2	threonyl-tRNA synthetase 2, mitochondrial (putative)	0.010
Ncoa3	nuclear receptor coactivator 3	0.010