IMP

Process View

Mus musculus

5 genes annotated in mouse

regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	1.000
Shh	sonic hedgehog	0.999
Fgf8	fibroblast growth factor 8	0.990
Gli3	GLI-Kruppel family member GLI3	0.985
Fgfr2	fibroblast growth factor receptor 2	0.984
Pou5f1	POU domain, class 5, transcription factor 1	0.935
Sall4	sal-like 4 (Drosophila)	0.926	Mouse
Lhx1	LIM homeobox protein 1	0.906
Rarg	retinoic acid receptor, gamma	0.884
Wnt3a	wingless-related MMTV integration site 3A	0.830	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.790
Tbx1	T-box 1	0.755
Hoxd11	homeobox D11	0.742
Pax8	paired box gene 8	0.738
Fgf3	fibroblast growth factor 3	0.719
Sox2	SRY-box containing gene 2	0.718
Gli2	GLI-Kruppel family member GLI2	0.718
Emx2	empty spiracles homolog 2 (Drosophila)	0.713
Sall1	sal-like 1 (Drosophila)	0.707
Otx2	orthodenticle homolog 2 (Drosophila)	0.675
Foxc1	forkhead box C1	0.642
Nog	noggin	0.637
Nanog	Nanog homeobox	0.637
T	brachyury	0.545
Fgf10	fibroblast growth factor 10	0.535
Otx1	orthodenticle homolog 1 (Drosophila)	0.501
Hoxa1	homeobox A1	0.500
Wnt4	wingless-related MMTV integration site 4	0.481	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.428
Bmp7	bone morphogenetic protein 7	0.408
Foxc2	forkhead box C2	0.374
Msx1	homeobox, msh-like 1	0.370
Dlx5	distal-less homeobox 5	0.357
Pax3	paired box gene 3	0.345
Rarb	retinoic acid receptor, beta	0.295
Hoxa11	homeobox A11	0.254
Hmx3	H6 homeobox 3	0.239
Hand1	heart and neural crest derivatives expressed transcript 1	0.239
Ret	ret proto-oncogene	0.222
Gbx2	gastrulation brain homeobox 2	0.222
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.218
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.213
Tcfcp2l1	transcription factor CP2-like 1	0.210
Twist2	twist homolog 2 (Drosophila)	0.210
Alx4	aristaless-like homeobox 4	0.201
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.197
Pax1	paired box gene 1	0.197	Mouse
Smo	smoothened homolog (Drosophila)	0.195
Sox9	SRY-box containing gene 9	0.177
Esrrb	estrogen related receptor, beta	0.173
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.156
Tcfap2c	transcription factor AP-2, gamma	0.144
Gdnf	glial cell line derived neurotrophic factor	0.138
Hoxd13	homeobox D13	0.133
Sall3	sal-like 3 (Drosophila)	0.127	Mouse
Hoxa3	homeobox A3	0.121
Fgfr1	fibroblast growth factor receptor 1	0.119
Hoxa2	homeobox A2	0.118
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.117
Wnt9b	wingless-type MMTV integration site 9B	0.116
Eya1	eyes absent 1 homolog (Drosophila)	0.113
Lef1	lymphoid enhancer binding factor 1	0.110
Hoxd3	homeobox D3	0.108
Vax1	ventral anterior homeobox containing gene 1	0.104
Ptk7	PTK7 protein tyrosine kinase 7	0.103
Rxra	retinoid X receptor alpha	0.100
Tcfap2a	transcription factor AP-2, alpha	0.094
Rara	retinoic acid receptor, alpha	0.093
Wnt10b	wingless related MMTV integration site 10b	0.087	Mouse
Hmx1	H6 homeobox 1	0.086
Crlf1	cytokine receptor-like factor 1	0.081
Bnc1	basonuclin 1	0.081
Lmx1b	LIM homeobox transcription factor 1 beta	0.079
Foxi1	forkhead box I1	0.079
Msx2	homeobox, msh-like 2	0.078
Neurog1	neurogenin 1	0.078
Adra2b	adrenergic receptor, alpha 2b	0.076
Foxd2	forkhead box D2	0.076
Hoxa13	homeobox A13	0.073
Wnt6	wingless-related MMTV integration site 6	0.072	Mouse
Grhl2	grainyhead-like 2 (Drosophila)	0.071
Gpr50	G-protein-coupled receptor 50	0.070
Hoxd9	homeobox D9	0.067
Pou3f1	POU domain, class 3, transcription factor 1	0.067
Wnt1	wingless-related MMTV integration site 1	0.064	Mouse
Acan	aggrecan	0.064
Pou3f3	POU domain, class 3, transcription factor 3	0.064
Wnt2b	wingless related MMTV integration site 2b	0.061	Mouse
Wt1	Wilms tumor 1 homolog	0.061
Pitx2	paired-like homeodomain transcription factor 2	0.056
Sim2	single-minded homolog 2 (Drosophila)	0.054
Bmp4	bone morphogenetic protein 4	0.053
Trp63	transformation related protein 63	0.053
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.050
Ephb2	Eph receptor B2	0.050
Fgfr3	fibroblast growth factor receptor 3	0.049
Wnt9a	wingless-type MMTV integration site 9A	0.046	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.045
Gata3	GATA binding protein 3	0.044
En1	engrailed 1	0.043
Sox3	SRY-box containing gene 3	0.039
Hoxb3	homeobox B3	0.037
Fgf15	fibroblast growth factor 15	0.036
Alx3	aristaless-like homeobox 3	0.036
Chrd	chordin	0.035
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.035
Foxb1	forkhead box B1	0.034
Kl	klotho	0.034
Col2a1	collagen, type II, alpha 1	0.034
Uncx	UNC homeobox	0.034
Gli1	GLI-Kruppel family member GLI1	0.033
Gdf11	growth differentiation factor 11	0.033
Pax9	paired box gene 9	0.031	Mouse
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.030
Vangl2	vang-like 2 (van gogh, Drosophila)	0.029
Barx1	BarH-like homeobox 1	0.029
Lama5	laminin, alpha 5	0.029
Amh	anti-Mullerian hormone	0.028
Barx2	BarH-like homeobox 2	0.027
Hoxc5	homeobox C5	0.027
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.026
Foxn1	forkhead box N1	0.025
Krt15	keratin 15	0.025
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.025
Prrx2	paired related homeobox 2	0.024
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.024
Hoxb6	homeobox B6	0.024
Pitx3	paired-like homeodomain transcription factor 3	0.024
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.024
Emx1	empty spiracles homolog 1 (Drosophila)	0.023
Hes5	hairy and enhancer of split 5 (Drosophila)	0.023
Hoxa10	homeobox A10	0.023
Ctnnb1	catenin (cadherin associated protein), beta 1	0.023
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.022
Emid2	EMI domain containing 2	0.022
Efna2	ephrin A2	0.022
Ihh	Indian hedgehog	0.021
Btbd17	BTB (POZ) domain containing 17	0.021
Fgf18	fibroblast growth factor 18	0.021
Fzd10	frizzled homolog 10 (Drosophila)	0.021
Krt14	keratin 14	0.020
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.020
Igh	immunoglobulin heavy chain complex	0.020
Krtdap	keratinocyte differentiation associated protein	0.020
Gjb4	gap junction protein, beta 4	0.019
Nkx6-1	NK6 homeobox 1	0.019
Nkx2-1	NK2 homeobox 1	0.019
Grem1	gremlin 1	0.019
Lhb	luteinizing hormone beta	0.019
Fgf4	fibroblast growth factor 4	0.019
Fgf5	fibroblast growth factor 5	0.019
Efna4	ephrin A4	0.019
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.019
Efnb2	ephrin B2	0.019
Hoxa4	homeobox A4	0.018
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.018
Nodal	nodal	0.018
Dlx1	distal-less homeobox 1	0.018
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.017
Hoxb1	homeobox B1	0.017
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.017
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.017
Tbx2	T-box 2	0.017
Sox11	SRY-box containing gene 11	0.016
Zic2	zinc finger protein of the cerebellum 2	0.016
Foxn4	forkhead box N4	0.016
Col22a1	collagen, type XXII, alpha 1	0.015
Krt17	keratin 17	0.015
Crabp2	cellular retinoic acid binding protein II	0.015
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.015
Prrx1	paired related homeobox 1	0.015
Sox1	SRY-box containing gene 1	0.015
Gsc	goosecoid homeobox	0.015
Fzd8	frizzled homolog 8 (Drosophila)	0.014
Actn3	actinin alpha 3	0.014
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.014
Omp	olfactory marker protein	0.014
Tbx15	T-box 15	0.014
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.014
Zeb1	zinc finger E-box binding homeobox 1	0.014
Hand2	heart and neural crest derivatives expressed transcript 2	0.014
Dlx4	distal-less homeobox 4	0.014
Pou3f2	POU domain, class 3, transcription factor 2	0.013
Irx1	Iroquois related homeobox 1 (Drosophila)	0.013
Chd7	chromodomain helicase DNA binding protein 7	0.013
BC024139	cDNA sequence BC024139	0.013
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.013
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.013
Tacr1	tachykinin receptor 1	0.013
Lhx5	LIM homeobox protein 5	0.012
Fxyd2	FXYD domain-containing ion transport regulator 2	0.012
Nkx3-2	NK3 homeobox 2	0.012
Socs1	suppressor of cytokine signaling 1	0.012
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.012
Tead3	TEA domain family member 3	0.012
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.012
Hoxd4	homeobox D4	0.012
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.011
Tbx3	T-box 3	0.011
Cdx1	caudal type homeobox 1	0.011
Tnni1	troponin I, skeletal, slow 1	0.011
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.011
Foxe3	forkhead box E3	0.011
Shox2	short stature homeobox 2	0.011
Hmx2	H6 homeobox 2	0.011
Hoxc6	homeobox C6	0.011
Zbtb7c	zinc finger and BTB domain containing 7C	0.011
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.011
Jag1	jagged 1	0.011
Hoxb9	homeobox B9	0.011
Il11	interleukin 11	0.011
Wnt10a	wingless related MMTV integration site 10a	0.011
Sox7	SRY-box containing gene 7	0.011
Col4a3	collagen, type IV, alpha 3	0.010
Twist1	twist homolog 1 (Drosophila)	0.010
Clic3	chloride intracellular channel 3	0.010
Bdkrb2	bradykinin receptor, beta 2	0.010
Npas1	neuronal PAS domain protein 1	0.010
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.010
Hoxa7	homeobox A7	0.010
Artn	artemin	0.010	Mouse
Dmbx1	diencephalon/mesencephalon homeobox 1	0.010