IMP

Process View

Mus musculus

1 genes annotated in mouse

renal capsule development

The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal capsule development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "renal capsule development" (in gray)

Name	Description	Probability	Func Analog Organism
Tbx1	T-box 1	0.990
Pax2	paired box gene 2	0.989
Foxc1	forkhead box C1	0.989	Mouse
Foxc2	forkhead box C2	0.947	Mouse
Pax6	paired box gene 6	0.940
Chd7	chromodomain helicase DNA binding protein 7	0.928
Hoxa1	homeobox A1	0.920
Fgfr2	fibroblast growth factor receptor 2	0.913
Shh	sonic hedgehog	0.912
Eya1	eyes absent 1 homolog (Drosophila)	0.890
Fgf8	fibroblast growth factor 8	0.856
Bmp4	bone morphogenetic protein 4	0.831
Pitx2	paired-like homeodomain transcription factor 2	0.813
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.813
Tgfb2	transforming growth factor, beta 2	0.780
Jag1	jagged 1	0.731
Pax3	paired box gene 3	0.668
Gbx2	gastrulation brain homeobox 2	0.590
Otx2	orthodenticle homolog 2 (Drosophila)	0.572
Tcfap2a	transcription factor AP-2, alpha	0.555
Lmx1a	LIM homeobox transcription factor 1 alpha	0.527
Hmx3	H6 homeobox 3	0.491
Gli3	GLI-Kruppel family member GLI3	0.488
Hand2	heart and neural crest derivatives expressed transcript 2	0.487
Efnb2	ephrin B2	0.404
Otx1	orthodenticle homolog 1 (Drosophila)	0.368
Gdnf	glial cell line derived neurotrophic factor	0.363
Hoxa3	homeobox A3	0.331
Hoxd3	homeobox D3	0.308
Vangl2	vang-like 2 (van gogh, Drosophila)	0.304
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.275
Dlx5	distal-less homeobox 5	0.268
Foxa2	forkhead box A2	0.245	Mouse
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.229
Lmx1b	LIM homeobox transcription factor 1 beta	0.227
Rarb	retinoic acid receptor, beta	0.222
Pax8	paired box gene 8	0.190
Meox2	mesenchyme homeobox 2	0.165
Rarg	retinoic acid receptor, gamma	0.160
Foxg1	forkhead box G1	0.152	Mouse
Hoxa2	homeobox A2	0.142
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.140
Nog	noggin	0.130
Foxa1	forkhead box A1	0.128	Mouse
Nkx2-1	NK2 homeobox 1	0.118
Gsc	goosecoid homeobox	0.117
Tbx10	T-box 10	0.115
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.114
Hoxd11	homeobox D11	0.098
Gata4	GATA binding protein 4	0.094
Foxe3	forkhead box E3	0.093	Mouse
Gli2	GLI-Kruppel family member GLI2	0.087
T	brachyury	0.085
Emx2	empty spiracles homolog 2 (Drosophila)	0.085
En1	engrailed 1	0.083
Nkx3-2	NK3 homeobox 2	0.083
Isl1	ISL1 transcription factor, LIM/homeodomain	0.081
Lhx1	LIM homeobox protein 1	0.080
Pax9	paired box gene 9	0.074
Foxf2	forkhead box F2	0.073
Ntf3	neurotrophin 3	0.072
Sox2	SRY-box containing gene 2	0.070
Zeb1	zinc finger E-box binding homeobox 1	0.068
Hoxb3	homeobox B3	0.066
Neurog1	neurogenin 1	0.065
Hoxd9	homeobox D9	0.063
Fgf3	fibroblast growth factor 3	0.060
Vegfa	vascular endothelial growth factor A	0.057
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.055
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.055
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.054
Matn3	matrilin 3	0.054
Wnt1	wingless-related MMTV integration site 1	0.054
Fgfr3	fibroblast growth factor receptor 3	0.053
Hand1	heart and neural crest derivatives expressed transcript 1	0.051
Ednra	endothelin receptor type A	0.049
Msx1	homeobox, msh-like 1	0.048
Pou4f3	POU domain, class 4, transcription factor 3	0.048
Mesp1	mesoderm posterior 1	0.047
Pou4f2	POU domain, class 4, transcription factor 2	0.046
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.046
Cdx1	caudal type homeobox 1	0.045
Bnc1	basonuclin 1	0.045
Hoxa9	homeobox A9	0.043
Cldn3	claudin 3	0.043
Smo	smoothened homolog (Drosophila)	0.041
Hoxb6	homeobox B6	0.040
Cldn8	claudin 8	0.040
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.038
Hmx1	H6 homeobox 1	0.038
Tcf21	transcription factor 21	0.038
Msx2	homeobox, msh-like 2	0.037
Hoxb5	homeobox B5	0.037
Gata3	GATA binding protein 3	0.035
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.035
Figla	folliculogenesis specific basic helix-loop-helix	0.034
Dmrt3	doublesex and mab-3 related transcription factor 3	0.033
Vax1	ventral anterior homeobox containing gene 1	0.033
Fgfr1	fibroblast growth factor receptor 1	0.032
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.032
Pbx1	pre B-cell leukemia transcription factor 1	0.032
Tlx3	T-cell leukemia, homeobox 3	0.031
Ptk7	PTK7 protein tyrosine kinase 7	0.030
Hmx2	H6 homeobox 2	0.030
Evx2	even skipped homeotic gene 2 homolog	0.029
Wnt7a	wingless-related MMTV integration site 7A	0.029
Foxb1	forkhead box B1	0.029
Psen1	presenilin 1	0.028
Pitx3	paired-like homeodomain transcription factor 3	0.028
Hoxc6	homeobox C6	0.026
Hoxc8	homeobox C8	0.026
Slc26a4	solute carrier family 26, member 4	0.026
Hoxa4	homeobox A4	0.025
Olfr70	olfactory receptor 70	0.025
Fgfrl1	fibroblast growth factor receptor-like 1	0.025
Zfp503	zinc finger protein 503	0.024
Hoxb8	homeobox B8	0.024
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.024
Cldn2	claudin 2	0.023
Hoxa10	homeobox A10	0.023
Irx1	Iroquois related homeobox 1 (Drosophila)	0.023
Foxl2	forkhead box L2	0.023	Mouse
Myf5	myogenic factor 5	0.022
Mecom	MDS1 and EVI1 complex locus	0.022
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.021
Twist2	twist homolog 2 (Drosophila)	0.021
Emx1	empty spiracles homolog 1 (Drosophila)	0.021
Wt1	Wilms tumor 1 homolog	0.021
Pax1	paired box gene 1	0.021
Sox9	SRY-box containing gene 9	0.021
Sftpb	surfactant associated protein B	0.020
Prrx2	paired related homeobox 2	0.020
Atoh1	atonal homolog 1 (Drosophila)	0.020
Sox1	SRY-box containing gene 1	0.020
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.019
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.019
Ihh	Indian hedgehog	0.018
Hoxb1	homeobox B1	0.018
Hoxd10	homeobox D10	0.018
Phlda2	pleckstrin homology-like domain, family A, member 2	0.018
Tmem30b	transmembrane protein 30B	0.018
Amh	anti-Mullerian hormone	0.018
Fgf10	fibroblast growth factor 10	0.018
Elf3	E74-like factor 3	0.017
Wfdc2	WAP four-disulfide core domain 2	0.017
BC057022	cDNA sequence BC057022	0.017
Gata6	GATA binding protein 6	0.017
Hoxa5	homeobox A5	0.017
Cldn4	claudin 4	0.017
Fzd10	frizzled homolog 10 (Drosophila)	0.017
Rdh10	retinol dehydrogenase 10 (all-trans)	0.016
Il25	interleukin 25	0.016
Hoxd1	homeobox D1	0.016
Hoxb2	homeobox B2	0.016
Tmprss2	transmembrane protease, serine 2	0.016
Pax7	paired box gene 7	0.016
Tgfbr2	transforming growth factor, beta receptor II	0.016
Emid2	EMI domain containing 2	0.016
Epn3	epsin 3	0.015
Hes5	hairy and enhancer of split 5 (Drosophila)	0.015
Zic1	zinc finger protein of the cerebellum 1	0.015
Sox7	SRY-box containing gene 7	0.015
Pcdh12	protocadherin 12	0.015
Hmga1	high mobility group AT-hook 1	0.015
Myod1	myogenic differentiation 1	0.014
Tlx2	T-cell leukemia, homeobox 2	0.014
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.014
Hif3a	hypoxia inducible factor 3, alpha subunit	0.014
Hoxb9	homeobox B9	0.014
Mycs	myc-like oncogene, s-myc protein	0.014
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.014
Kremen2	kringle containing transmembrane protein 2	0.013
Sox3	SRY-box containing gene 3	0.013
Sox11	SRY-box containing gene 11	0.013
Hes1	hairy and enhancer of split 1 (Drosophila)	0.013
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.013
Foxh1	forkhead box H1	0.013
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.013
Evx1	even skipped homeotic gene 1 homolog	0.013
Tbx2	T-box 2	0.013
Adra2b	adrenergic receptor, alpha 2b	0.013
Cldn11	claudin 11	0.013
Cdh1	cadherin 1	0.013
1700014N06Rik	RIKEN cDNA 1700014N06 gene	0.013
Hoxd8	homeobox D8	0.013
Nccrp1	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)	0.012
Col13a1	collagen, type XIII, alpha 1	0.012
Foxd4	forkhead box D4	0.012	Mouse
Foxq1	forkhead box Q1	0.012	Mouse
Hoxd4	homeobox D4	0.012
Bmp7	bone morphogenetic protein 7	0.012
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.012
Uncx	UNC homeobox	0.012
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.012
Sall4	sal-like 4 (Drosophila)	0.012
Adcyap1	adenylate cyclase activating polypeptide 1	0.012
Ccdc96	coiled-coil domain containing 96	0.012
Bdnf	brain derived neurotrophic factor	0.011
Adam17	a disintegrin and metallopeptidase domain 17	0.011
Vgll2	vestigial like 2 homolog (Drosophila)	0.011
Hnf1b	HNF1 homeobox B	0.011
Col17a1	collagen, type XVII, alpha 1	0.011
Dhh	desert hedgehog	0.011
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.011
BC021785	cDNA sequence BC021785	0.011
Ocln	occludin	0.011
Foxa3	forkhead box A3	0.011	Mouse
Hoxa11	homeobox A11	0.011
Pthlh	parathyroid hormone-like peptide	0.011
Twist1	twist homolog 1 (Drosophila)	0.011
Ctnnb1	catenin (cadherin associated protein), beta 1	0.011
Foxi3	forkhead box I3	0.011
Gabrp	gamma-aminobutyric acid (GABA) A receptor, pi	0.011
Cckar	cholecystokinin A receptor	0.011
Zic2	zinc finger protein of the cerebellum 2	0.011
Snai1	snail homolog 1 (Drosophila)	0.011
Lefty1	left right determination factor 1	0.011
Esrp1	epithelial splicing regulatory protein 1	0.010
Dlx2	distal-less homeobox 2	0.010
Sox21	SRY-box containing gene 21	0.010
Pdx1	pancreatic and duodenal homeobox 1	0.010
Cldn23	claudin 23	0.010
Tshz1	teashirt zinc finger family member 1	0.010
Marveld3	MARVEL (membrane-associating) domain containing 3	0.010
Gsx1	GS homeobox 1	0.010
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.010