IMP

Process View

Mus musculus

10 genes annotated in mouse

positive regulation of mast cell activation involved in immune response

Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mast cell activation involved in immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of mast cell activation involved in immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Inpp5d	inositol polyphosphate-5-phosphatase D	0.982
Ptprc	protein tyrosine phosphatase, receptor type, C	0.951
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.931
Il4	interleukin 4	0.778
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.659	Mouse
Mefv	Mediterranean fever	0.570
Cd247	CD247 antigen	0.506	Mouse
Grb2	growth factor receptor bound protein 2	0.484
Hcst	hematopoietic cell signal transducer	0.470
Cd19	CD19 antigen	0.356
Ikzf1	IKAROS family zinc finger 1	0.351
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.263	Mouse
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.213	Mouse
Ccr6	chemokine (C-C motif) receptor 6	0.193
Lck	lymphocyte protein tyrosine kinase	0.188	Mouse
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.184
Lat	linker for activation of T cells	0.158
Cd40	CD40 antigen	0.152
Cd22	CD22 antigen	0.146
Tyrobp	TYRO protein tyrosine kinase binding protein	0.143
Tcra	T-cell receptor alpha chain	0.109
Il2	interleukin 2	0.108
Lyz2	lysozyme 2	0.106
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.105
Met	met proto-oncogene	0.097
Was	Wiskott-Aldrich syndrome homolog (human)	0.091
Dok2	docking protein 2	0.089
Il2rg	interleukin 2 receptor, gamma chain	0.087
Cd8a	CD8 antigen, alpha chain	0.081
Clec4n	C-type lectin domain family 4, member n	0.069
Cd4	CD4 antigen	0.068
Cbl	Casitas B-lineage lymphoma	0.066
Dok1	docking protein 1	0.057
Rag1	recombination activating gene 1	0.057
Csf1r	colony stimulating factor 1 receptor	0.056
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.053
Dok3	docking protein 3	0.049
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.047
Tnf	tumor necrosis factor	0.046
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.044
Ifng	interferon gamma	0.044
Tbxas1	thromboxane A synthase 1, platelet	0.041
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.037
Nfam1	Nfat activating molecule with ITAM motif 1	0.034
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.033
Kit	kit oncogene	0.033
Cd7	CD7 antigen	0.033
Plcg2	phospholipase C, gamma 2	0.032
Msr1	macrophage scavenger receptor 1	0.032
Mb	myoglobin	0.030
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.028
Cd28	CD28 antigen	0.028
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.027
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.026
Sfpi1	SFFV proviral integration 1	0.025
Cd180	CD180 antigen	0.025
Fyn	Fyn proto-oncogene	0.024	Mouse
Plcg1	phospholipase C, gamma 1	0.023
Itgb2	integrin beta 2	0.023
4632428N05Rik	RIKEN cDNA 4632428N05 gene	0.023
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.022	Mouse
Lair1	leukocyte-associated Ig-like receptor 1	0.021
Ifngr1	interferon gamma receptor 1	0.020
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.020
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.020
BC013712	cDNA sequence BC013712	0.019
Ptk2	PTK2 protein tyrosine kinase 2	0.019
Shc1	src homology 2 domain-containing transforming protein C1	0.019
AF251705	cDNA sequence AF251705	0.019	Mouse
Prkce	protein kinase C, epsilon	0.019
Trem3	triggering receptor expressed on myeloid cells 3	0.019
Zap70	zeta-chain (TCR) associated protein kinase	0.018	Mouse
Cd68	CD68 antigen	0.018
Pou2af1	POU domain, class 2, associating factor 1	0.018
Igk	immunoglobulin kappa chain complex	0.018
Cd5	CD5 antigen	0.018
Il10ra	interleukin 10 receptor, alpha	0.017
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.017
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.017
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.017
Il2rb	interleukin 2 receptor, beta chain	0.016
Irg1	immunoresponsive gene 1	0.015
Cd300lf	CD300 antigen like family member F	0.015	Mouse
Rgs14	regulator of G-protein signaling 14	0.015
F7	coagulation factor VII	0.015
Itgax	integrin alpha X	0.015
Ptpre	protein tyrosine phosphatase, receptor type, E	0.014
Stat6	signal transducer and activator of transcription 6	0.014
Mmp8	matrix metallopeptidase 8	0.014
Ccr1	chemokine (C-C motif) receptor 1	0.014
Treml1	triggering receptor expressed on myeloid cells-like 1	0.014
Pilra	paired immunoglobin-like type 2 receptor alpha	0.013
Plek	pleckstrin	0.013
Clec4d	C-type lectin domain family 4, member d	0.013
Mcoln2	mucolipin 2	0.013
Il1b	interleukin 1 beta	0.012
Pdcd1	programmed cell death 1	0.012
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.012
C3ar1	complement component 3a receptor 1	0.012
Ccl8	chemokine (C-C motif) ligand 8	0.012
Laptm5	lysosomal-associated protein transmembrane 5	0.011
Nos2	nitric oxide synthase 2, inducible	0.011
Pou2f2	POU domain, class 2, transcription factor 2	0.011
Slamf1	signaling lymphocytic activation molecule family member 1	0.011
Il15	interleukin 15	0.011
Fasl	Fas ligand (TNF superfamily, member 6)	0.011
Grap2	GRB2-related adaptor protein 2	0.011
Cxcr3	chemokine (C-X-C motif) receptor 3	0.011
Il4ra	interleukin 4 receptor, alpha	0.011
S1pr4	sphingosine-1-phosphate receptor 4	0.011
Ebi3	Epstein-Barr virus induced gene 3	0.011
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.011
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.010
Rel	reticuloendotheliosis oncogene	0.010
Rac2	RAS-related C3 botulinum substrate 2	0.010
Cd86	CD86 antigen	0.010
Fcgr3	Fc receptor, IgG, low affinity III	0.010	Mouse
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.010
Ncf1	neutrophil cytosolic factor 1	0.010