IMP

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Rattus norvegicus

0 genes annotated in rat

dilated cardiomyopathy

DOID:12930

An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently and characterized by an enlarged heart.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dilated cardiomyopathy" (in gray)

Name	Description	Probability	Func Analog Organism
Myh6	myosin, heavy chain 6, cardiac muscle, alpha	0.946	Human
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.800
Actn2	actinin alpha 2	0.743
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.708
Casq2	calsequestrin 2 (cardiac muscle)	0.704
Csrp3	cysteine and glycine-rich protein 3	0.641	Human
Ckm	creatine kinase, muscle	0.604
Actc1	actin, alpha, cardiac muscle 1	0.529	Human
Cox6a2	cytochrome c oxidase, subunit VIa, polypeptide 2	0.461
Myh7	myosin, heavy chain 7, cardiac muscle, beta	0.400	Human
Myl3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.389
Myoz2	myozenin 2	0.334
Hspb1	heat shock protein 1	0.306
Mb	myoglobin	0.232
Pgam2	phosphoglycerate mutase 2 (muscle)	0.218
Smpx	small muscle protein, X-linked	0.198
Pygm	phosphorylase, glycogen, muscle	0.148
Pdlim3	PDZ and LIM domain 3	0.089
Tpm1	tropomyosin 1, alpha	0.085
Ckmt2	creatine kinase, mitochondrial 2, sarcomeric	0.078
Tnni3	troponin I type 3 (cardiac)	0.069
Des	desmin	0.063	Human
Xirp1	xin actin-binding repeat containing 1	0.060
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.056
Cox8b	cytochrome c oxidase, subunit VIIIb	0.056
Unc45b	unc-45 homolog B (C. elegans)	0.048
Rrbp1	ribosome binding protein 1	0.043
Flnc	filamin C, gamma	0.043
Asb2	ankyrin repeat and SOCS box-containing 2	0.042
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.042
Bdkrb2	bradykinin receptor B2	0.041
Obscn	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.041
Myh9	myosin, heavy chain 9, non-muscle	0.041
Cav3	caveolin 3	0.040
Plec	plectin	0.038
Flna	filamin A, alpha	0.037
Zyx	zyxin	0.037
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.034
Mybph	myosin binding protein H	0.029
Nrap	nebulin-related anchoring protein	0.028
PVR	poliovirus receptor	0.028
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.028
Hbegf	heparin-binding EGF-like growth factor	0.027
Acta1	actin, alpha 1, skeletal muscle	0.027
Lrp10	low-density lipoprotein receptor-related protein 10	0.026
Gata4	GATA binding protein 4	0.026
Myh2	myosin, heavy chain 2, skeletal muscle, adult	0.024
Cryab	crystallin, alpha B	0.022	Human
Anxa5	annexin A5	0.022
Slc25a4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	0.022
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.021
Lmod2	leiomodin 2 (cardiac)	0.021
Podxl	podocalyxin-like	0.021
Sln	sarcolipin	0.020
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.019
Eif3b	eukaryotic translation initiation factor 3, subunit B	0.019
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.019
Csda	cold shock domain protein A	0.018
Pdlim1	PDZ and LIM domain 1	0.018
Ninj1	ninjurin 1	0.018
Hspb2	heat shock protein beta 2	0.018
Tln1	talin 1	0.018
Mybpc1	myosin binding protein C, slow type	0.017
Vat1	vesicle amine transport protein 1 homolog (T californica)	0.017
Mgp	matrix Gla protein	0.017
Ehd4	EH-domain containing 4	0.017
Trim28	tripartite motif-containing 28	0.016
Fabp3	fatty acid binding protein 3, muscle and heart	0.015
Ldb3	LIM domain binding 3	0.015	Human
Art1	ADP-ribosyltransferase 1	0.015
Tnnc1	troponin C type 1 (slow)	0.015	Human
Uqcrc1	ubiquinol-cytochrome c reductase core protein I	0.015
Lrch4	leucine-rich repeats and calponin homology (CH) domain containing 4	0.015
P2rx5	purinergic receptor P2X, ligand-gated ion channel, 5	0.015
Ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.015
Jarid1a	jumonji, AT rich interactive domain 1A (Rbp2 like)	0.014
Pmepa1	prostate transmembrane protein, androgen induced 1	0.014
Has2	hyaluronan synthase 2	0.014
Asb12	ankyrin repeat and SOCS box-containing 12	0.014
Thbs4	thrombospondin 4	0.014
Fam129b	family with sequence similarity 129, member B	0.013
Gnrh1	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	0.013
Mybpc2	myosin binding protein C, fast-type	0.012
Hspb8	heat shock protein B8	0.012
Arfgap1	ADP-ribosylation factor GTPase activating protein 1	0.012
Pln	phospholamban	0.012
Slc12a4	solute carrier family 12 (potassium/chloride transporters), member 4	0.012
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.012
Emp3	epithelial membrane protein 3	0.012
Hk2	hexokinase 2	0.011
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.011
Tagln	transgelin	0.011
Cd99	CD99 antigen	0.011
Tgm2	transglutaminase 2, C polypeptide	0.011
Trim54	tripartite motif-containing 54	0.011
Hspa1a	heat shock 70kD protein 1A	0.011
Nudt8	nudix (nucleoside diphosphate linked moiety X)-type motif 8	0.011
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.011
Ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.011
Myadm	myeloid-associated differentiation marker	0.010
LOC298139	similar to RIKEN cDNA 2310003M01	0.010