IMP

Process View

Rattus norvegicus

1 genes annotated in rat

Multi-species View

positive regulation of tolerance induction

GO:0002645

Any process that activates or increases the frequency, rate, or extent of tolerance induction.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of tolerance induction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of tolerance induction" (in gray)

Name	Description	Probability	Func Analog Organism
RT1-EC2	RT1 class Ib, locus EC2	1.000
RT1-CE12	RT1 class I, locus CE12	0.918
RT1-S3	RT1 class Ib, locus S3	0.676	Rat
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.575
Irf7	interferon regulatory factor 7	0.502
LOC100364500	RT1 class I, locus CE11-like	0.485
B2m	beta-2 microglobulin	0.480
Lgals9	lectin, galactoside-binding, soluble, 9	0.445
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.384
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.186
Oas1a	2'-5' oligoadenylate synthetase 1A	0.167
Met	met proto-oncogene	0.139
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.138	Rat
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.121
Ifi35	interferon-induced protein 35	0.117
Olr837	olfactory receptor 837	0.117
RT1-N3	RT1 class Ib, locus N3	0.110	Rat
Sorbs1	sorbin and SH3 domain containing 1	0.104
Olr37	olfactory receptor 37	0.094
Dock8	dedicator of cytokinesis 8	0.090
Cxcl10	chemokine (C-X-C motif) ligand 10	0.087
Calcrl	calcitonin receptor-like	0.086
RT1-CE5	RT1 class I, locus CE5	0.082	Rat
Cxcl9	chemokine (C-X-C motif) ligand 9	0.082
Irf1	interferon regulatory factor 1	0.075
RT1-Cl	RT1 class Ib, locus Cl	0.075
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.074
Capn5	calpain 5	0.071
F9	coagulation factor IX	0.068
LOC100365106	rCG32755-like	0.067
Foxc2	forkhead box C2	0.056
Rsad2	radical S-adenosyl methionine domain containing 2	0.055
Shc3	SHC (Src homology 2 domain containing) transforming protein 3	0.055
Lgals5	lectin, galactose binding, soluble 5	0.052
Cd37	CD37 molecule	0.049
Arnt	aryl hydrocarbon receptor nuclear translocator	0.049
Mx1	myxovirus (influenza virus) resistance 1	0.049
Parp14	poly (ADP-ribose) polymerase family, member 14	0.048
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.046
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.046
Anpep	alanyl (membrane) aminopeptidase	0.043
Hfe	hemochromatosis	0.042	Rat
RT1-CE16	RT1 class I, locus CE16	0.041
Stat1	signal transducer and activator of transcription 1	0.039
Gbp2	guanylate binding protein 2	0.039
Hnf4a	hepatocyte nuclear factor 4, alpha	0.038
Clic4	chloride intracellular channel 4	0.037
Trim47	tripartite motif-containing 47	0.036
Sardh	sarcosine dehydrogenase	0.036
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.036
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.036
Cyba	cytochrome b-245, alpha polypeptide	0.035
Igtp	interferon gamma induced GTPase	0.034
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.034
Ccl5	chemokine (C-C motif) ligand 5	0.033
Itga6	integrin, alpha 6	0.033
Adam10	ADAM metallopeptidase domain 10	0.032
LOC100360587	hypothetical protein LOC100360587	0.032
Sod3	superoxide dismutase 3, extracellular	0.032
Ppara	peroxisome proliferator activated receptor alpha	0.031
Otc	ornithine carbamoyltransferase	0.031
Rbm5	RNA binding motif protein 5	0.030
Bmp6	bone morphogenetic protein 6	0.030
Bst2	bone marrow stromal cell antigen 2	0.029
Man2b1	mannosidase, alpha, class 2B, member 1	0.029
Galr3	galanin receptor 3	0.029
Plbd2	phospholipase B domain containing 2	0.028
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.027
Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C	0.027
Parp9	poly (ADP-ribose) polymerase family, member 9	0.027
Tapbp	TAP binding protein	0.025
RT1-CE2	RT1 class I, locus CE2	0.024	Rat
Elf1	E74-like factor 1	0.024
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.023
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.023
C8b	complement component 8, beta polypeptide	0.023
Rtp4	receptor (chemosensory) transporter protein 4	0.022
Tgfbr2	transforming growth factor, beta receptor II	0.022	Mouse
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.022
Slc22a18	solute carrier family 22, member 18	0.022
Gbp5	guanylate binding protein 5	0.022
Plg	plasminogen	0.021
Il8ra	interleukin 8 receptor, alpha	0.021
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.020
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.020
Mgat1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.020
Akr1c14	aldo-keto reductase family 1, member C14	0.020
RT1-M6-2	RT1 class I, locus M6, gene 2	0.020	Rat
Ocln	occludin	0.020
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.020
Cd4	Cd4 molecule	0.020
RT1-CE4	RT1 class I, locus CE4	0.020	Rat
Itgb5	integrin, beta 5	0.019
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.019
RT1-Ba	RT1 class II, locus Ba	0.019
RT1-CE15	RT1 class I, locus CE15	0.018
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.018
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.018
Ctsh	cathepsin H	0.018
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.018
Tgfbr3	transforming growth factor, beta receptor III	0.018
C2	complement component 2	0.018
Brd4	bromodomain containing 4	0.018
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.017
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.017
RGD1559588	similar to cell surface receptor FDFACT	0.017
Casp8	caspase 8	0.017
Myo1d	myosin ID	0.017
Cdc2l6	cell division cycle 2-like 6 (CDK8-like)	0.017
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.017
Uba7	ubiquitin-like modifier activating enzyme 7	0.017
Fbln5	fibulin 5	0.017
RT1-CE1	RT1 class I, locus1	0.016	Rat
Stat5b	signal transducer and activator of transcription 5B	0.016
Parp3	poly (ADP-ribose) polymerase family, member 3	0.016
Ptch1	patched homolog 1 (Drosophila)	0.016
Akt2	v-akt murine thymoma viral oncogene homolog 2	0.016
Il1r1	interleukin 1 receptor, type I	0.016
Neurl3	neuralized homolog 3 (Drosophila)	0.016
Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.016
Asgr1	asialoglycoprotein receptor 1	0.016
B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.016
Galm	galactose mutarotase (aldose 1-epimerase)	0.016
Cmtm4	CKLF-like MARVEL transmembrane domain containing 4	0.016
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.015
Hpn	hepsin	0.015
Mycbp2	MYC binding protein 2	0.015
Cyp2b15	cytochrome P450, family 2, subfamily b, polypeptide 15	0.015
Id3	inhibitor of DNA binding 3	0.015
Tgfbr1	transforming growth factor, beta receptor 1	0.015
Nras	neuroblastoma ras oncogene	0.015
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.015
Dmgdh	dimethylglycine dehydrogenase	0.015
Gpr65	G-protein coupled receptor 65	0.014
Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	0.014
Serpinb9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.014
LOC680711	hypothetical protein LOC680711	0.014
Serpina1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.014
Chek2	CHK2 checkpoint homolog (S. pombe)	0.014
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.014
Mc3r	melanocortin 3 receptor	0.014
Fgfr2	fibroblast growth factor receptor 2	0.014
Zc3hav1l	zinc finger CCCH-type, antiviral 1-like	0.014
Mbl1	mannose-binding lectin (protein A) 1	0.013
RT1-T24-1	RT1 class I, locus T24, gene 1	0.013	Rat
Olr1082	olfactory receptor 1082	0.013
Insl3	insulin-like 3	0.013
Dnah8	dynein, axonemal, heavy chain 8	0.013
Fgf1	fibroblast growth factor 1	0.013
LOC100364485	mCG1051031-like	0.013
Slfn3	schlafen 3	0.013
Smad3	SMAD family member 3	0.013
Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.013
RT1-T24-4	RT1 class I, locus T24, gene 4	0.013
Spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.013
Stx2	syntaxin 2	0.013
RGD1305793	similar to hypothetical protein FLJ20154	0.013
Ifi44l	interferon-induced protein 44-like	0.013
RT1-CE3	RT1 class I, locus CE3	0.013	Rat
Prcp	prolylcarboxypeptidase (angiotensinase C)	0.013
Hyal2	hyaluronoglucosaminidase 2	0.013
Crygf	crystallin, gamma F	0.013
Ahr	aryl hydrocarbon receptor	0.012
Socs3	suppressor of cytokine signaling 3	0.012
Tspan4	tetraspanin 4	0.012
Nmi	N-myc (and STAT) interactor	0.012
Cd300lf	CD300 molecule-like family member f	0.012
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.012
Olr1362	olfactory receptor 1362	0.012
Pla2g2c	phospholipase A2, group IIC	0.012
Ifi27	interferon, alpha-inducible protein 27	0.012
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.012
Vgll2	vestigial like 2 (Drosophila)	0.012
Ly6b	lymphocyte antigen 6 complex, locus B	0.012
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.012
Artn	artemin	0.012
Lifr	leukemia inhibitory factor receptor alpha	0.012
LOC100360103	hypothetical protein LOC100360103	0.012
Phactr2	phosphatase and actin regulator 2	0.012
Gimap8	GTPase, IMAP family member 8	0.012
Smad6	SMAD family member 6	0.012
Map3k3	mitogen activated protein kinase kinase kinase 3	0.012
Apol3	apolipoprotein L, 3	0.012
Fyn	FYN oncogene related to SRC, FGR, YES	0.012
Ttc30a1	tetratricopeptide repeat domain 30A1	0.012
Fzd5	frizzled homolog 5 (Drosophila)	0.012
Aif1	allograft inflammatory factor 1	0.011
Cfb	complement factor B	0.011
Yy1	YY1 transcription factor	0.011
A1i3	alpha-1-inhibitor III	0.011
RGD1562091	similar to expressed sequence C79127	0.011
Impdh1	IMP (inosine monophosphate) dehydrogenase 1	0.011
Irf8	interferon regulatory factor 8	0.011
RT1-CE10	RT1 class I, locus CE10	0.011	Rat
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.011
Srrm2	serine/arginine repetitive matrix 2	0.011
Mical3	microtubule associated monoxygenase, calponin and LIM domain containing 3	0.011
Gsta2	glutathione S-transferase A2	0.011
Oas1i	2 ' -5 ' oligoadenylate synthetase 1I	0.011
Loh12cr1	loss of heterozygosity, 12, chromosomal region 1 homolog (human)	0.011
Glt25d1	glycosyltransferase 25 domain containing 1	0.011
Txnip	thioredoxin interacting protein	0.011
Snrk	SNF related kinase	0.011
Syt8	synaptotagmin VIII	0.011
RGD1306526	hypothetical LOC310764	0.011
Myo1a	myosin IA	0.011
Cdh8	cadherin 8	0.011
LOC688090	similar to RT1 class II histocompatibility antigen, B-1 beta chain precursor (RT1.B-beta(1))	0.011
Apoa5	apolipoprotein A-V	0.011
Ggt5	gamma-glutamyltransferase 5	0.011
Ell	elongation factor RNA polymerase II	0.011
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.011
Fam172a	family with sequence similarity 172, member A	0.011
Gstm2	glutathione S-transferase mu 2	0.011
Fgf2	fibroblast growth factor 2	0.011
Np	nucleoside phosphorylase	0.011
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.011
LOC679612	hypothetical protein LOC679612	0.011
Cradd	CASP2 and RIPK1 domain containing adaptor with death domain	0.010
Rab13	RAB13, member RAS oncogene family	0.010
Tapbpl	TAP binding protein-like	0.010
Jrkl	jerky homolog-like (mouse)	0.010
Mosc2	MOCO sulphurase C-terminal domain containing 2	0.010
B9d2	B9 protein domain 2	0.010
Cela2a	chymotrypsin-like elastase family, member 2A	0.010
Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	0.010
Toe1	target of EGR1, member 1 (nuclear)	0.010
Izumo1	izumo sperm-egg fusion 1	0.010
Rps6kb2	ribosomal protein S6 kinase, polypeptide 2	0.010
Olr592	olfactory receptor 592	0.010
Olr1346	olfactory receptor 1346	0.010
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.010
Gna13	guanine nucleotide binding protein (G protein), alpha 13	0.010
Klri1	killer cell lectin-like receptor family I member 1	0.010