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Process View

Danio rerio

2 genes annotated in zebrafish

regulation of wnt signaling pathway involved in heart development

Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of wnt signaling pathway involved in heart development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of wnt signaling pathway involved in heart development" (in gray)

Name	Description	Probability	Func Analog Organism
bmp4	bone morphogenetic protein 4	0.906
tbx1	T-box 1	0.867
wnt5b	wingless-type MMTV integration site family, member 5b	0.862
bmp2b	bone morphogenetic protein 2b	0.777	Human
tbx16	T-box gene 16	0.664
ved	ventrally expressed dharma/bozozok antagonist	0.498
chd	chordin	0.455
mespa	mesoderm posterior a	0.400	Mouse
dlx3b	distal-less homeobox gene 3b	0.360
pcdh8	protocadherin 8	0.358
lft1	lefty1	0.306
foxd5	forkhead box D5	0.299
eve1	even-skipped-like1	0.269
pkd2	polycystic kidney disease 2	0.197
vox	ventral homeobox	0.194
mespb	mesoderm posterior b	0.171	Mouse
sox17	SRY-box containing gene 17	0.169	Mouse
vent	ventral expressed homeobox	0.161
lamb1a	laminin, beta 1a	0.156
bmp2a	bone morphogenetic protein 2a	0.155	Human
tbx6	T-box gene 6	0.126
tll1	tolloid-like 1	0.115
her5	hairy-related 5	0.112
bmp7a	bone morphogenetic protein 7a	0.109
osr1	odd-skipped related 1 (Drosophila)	0.103
has2	hyaluronan synthase 2	0.103
sox32	SRY-box containing gene 32	0.088	Mouse
aplnra	apelin receptor a	0.087
cdh1	cadherin 1, epithelial	0.085
tp63	tumor protein p63	0.081
ntla	no tail a	0.079
her1	hairy-related 1	0.076
ihha	Indian hedgehog homolog a	0.074
drl	draculin	0.072
klf4	Kruppel-like factor 4	0.071
snai1a	snail homolog 1a (Drosophila)	0.070
wnt11	wingless-type MMTV integration site family, member 11	0.069
ndr2	nodal-related 2	0.069
gata5	GATA-binding protein 5	0.065
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.064
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.062
cdh2	cadherin 2, neuronal	0.061
msxc	muscle segment homeobox C	0.060
cd63	Cd63 antigen	0.060
admp	anti-dorsalizing morphogenic protein	0.059
fbn2b	fibrillin 2b	0.057
vasa	vasa homolog	0.057
foxi1	forkhead box I1	0.052
fgf8a	fibroblast growth factor 8 a	0.052
oep	one-eyed pinhead	0.051
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.050
mesp2	mesoderm posterior 2 homolog (mouse)	0.048
cdx4	caudal type homeo box transcription factor 4	0.045
fgf17	fibroblast growth factor 17	0.043
ripply1	ripply1	0.043
tagln2	transgelin 2	0.041
smad5	MAD homolog 5 (Drosophila)	0.041
msxd	muscle segment homeobox D	0.038
wnt10a	wingless-type MMTV integration site family, member 10a	0.038
foxa3	forkhead box A3	0.038
fgf24	fibroblast growth factor 24	0.033
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.032
perp	PERP, TP53 apoptosis effector	0.032
nkx2.5	NK2 transcription factor related 5	0.031
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.030
dlx5a	distal-less homeobox gene 5a	0.030
nrarpa	notch-regulated ankyrin repeat protein a	0.030
gata6	GATA-binding protein 6	0.030
gpc4	glypican 4	0.028
tbx24	T-box 24	0.028
fancd2	Fanconi anemia, complementation group D2	0.028
angpt2	angiopoietin 2	0.026
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.026
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.026
smo	smoothened homolog (Drosophila)	0.025
nog1	noggin 1	0.025
dlx4b	distal-less homeobox gene 4b	0.024
tbx20	T-box 20	0.024
llgl2	lethal giant larvae homolog 2 (Drosophila)	0.024
tbpl2	TATA box binding protein like 2	0.023
lft2	lefty2	0.023
gdf6b	growth differentiation factor 6b	0.021
sp7	Sp7 transcription factor	0.021
cnot1	CCR4-NOT transcription complex, subunit 1	0.021
zgc:158603	zgc:158603	0.021
tp73	tumor protein p73	0.020
ahnak	AHNAK nucleoprotein	0.020
si:dkey-21k24.2	si:dkey-21k24.2	0.020
acvr1b	activin A receptor, type IB	0.019
celf1	cugbp, Elav-like family member 1	0.019
dharma	dharma	0.018
igf1rb	insulin-like growth factor 1b receptor	0.018
apoeb	apolipoprotein Eb	0.018
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.017
her7	hairy and enhancer of split related-7	0.017
gro2	groucho 2	0.017
chsy1	chondroitin sulfate synthase 1	0.017
wls	wntless homolog (Drosophila)	0.016
fzd10	frizzled homolog 10	0.016
aplnrb	apelin receptor b	0.016
krt8	keratin 8	0.016
six4a	sine oculis homeobox homolog 4a	0.015
furina	furin (paired basic amino acid cleaving enzyme) a	0.015
hhex	hematopoietically expressed homeobox	0.015
gata4	GATA-binding protein 4	0.015
im:7163548	im:7163548	0.015
msgn1	mesogenin 1	0.015
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.015
tie1	endothelium-specific receptor tyrosine kinase 1	0.015
krt4	keratin 4	0.014
acvr1l	activin A receptor, type I like	0.014
zgc:85975	zgc:85975	0.014
frem2a	Fras1 related extracellular matrix protein 2a	0.014
dsc2l	desmocollin 2 like	0.014
mxtx1	mix-type homeobox gene 1	0.013
dusp6	dual specificity phosphatase 6	0.013
ndr1	nodal-related 1	0.013
gmds	GDP-mannose 4,6-dehydratase	0.013
hoxa9b	homeo box A9b	0.013
ncor1	nuclear receptor co-repressor 1	0.013
prdm1a	PR domain containing 1a, with ZNF domain	0.012
mmp2	matrix metalloproteinase 2	0.012
tjp2a	tight junction protein 2a (zona occludens 2)	0.012
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.012
hand2	heart and neural crest derivatives expressed transcript 2	0.012
msxb	muscle segment homeobox B	0.011
ripply2	ripply2	0.011
lama5	laminin, alpha 5	0.011
wnt8a	wingless-type MMTV integration site family, member 8a	0.011
hnf1ba	HNF1 homeobox Ba	0.011
ryk	receptor-like tyrosine kinase	0.011
igf1ra	insulin-like growth factor 1a receptor	0.011
si:ch211-235f6.2	si:ch211-235f6.2	0.011
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.011
sdprb	serum deprivation response b	0.011
comta	catechol-O-methyltransferase a	0.011
pbx4	pre-B-cell leukemia transcription factor 4	0.010
mgp	matrix Gla protein	0.010
ubr5	ubiquitin protein ligase E3 component n-recognin 5	0.010
ef1	ETS-related factor1	0.010
alcamb	activated leukocyte cell adhesion molecule b	0.010
szl	sizzled	0.010
pld1a	phospholipase D1a	0.010
gpr126	G protein-coupled receptor 126	0.010
etv2	ets variant gene 2	0.010
wnt9b	wingless-type MMTV integration site family, member 9B	0.010
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.010